Asymmetric reduction of α, β-unsaturated ketone to (R) allylic alcohol by Candida chilensis
(2006)
Journal Article
Pollard, D. J., Telari, K., Lane, J., Humphrey, G., McWilliams, C., Nidositko, S., Salmon, P., & Moore, J. (2006). Asymmetric reduction of α, β-unsaturated ketone to (R) allylic alcohol by Candida chilensis. Biotechnology and Bioengineering, 93(4), 674-686. https://doi.org/10.1002/bit.20751
A pilot scale whole cell process was developed for the enantioselective 1,2‐reduction of prochiral α,β‐unsaturated ketone to (R) allylic alcohol using Candida chilensis. Initial development showed high enantiomeric excess (EE > 95%) but low product y... Read More about Asymmetric reduction of α, β-unsaturated ketone to (R) allylic alcohol by Candida chilensis.