Neither Hide Nor Hair: The Difficulty of Identifying Useful Disease Biomarkers

Huett, Alan; Xavier, Ramnik J.

Abstract

Robert Koch was the first to propose a series of definitive tests to determine the agents of infectious disease. Koch's postulates, first published in 1890, were subsequently updated for the molecular era in 1988 by Stanley Falkow1 and continue to form the cornerstone of molecular pathogenesis. Indeed, detection of pathogen-associated molecules are widely used in diagnostic clinical tests,2, 3, 4 especially in cases where alternative methods are both slow and expensive [...]

Citation

Huett, A., & Xavier, R. J. (2008). Neither Hide Nor Hair: The Difficulty of Identifying Useful Disease Biomarkers. Gastroenterology, 134(7), 2164-2168. https://doi.org/10.1053/j.gastro.2008.04.013

• Journal Article Type: Editorial
• Online Publication Date: May 20, 2008
• Publication Date: Jun 1, 2008
• Deposit Date: Aug 15, 2022
• Journal: Gastroenterology
• Print ISSN: 0016-5085
• Electronic ISSN: 1528-0012
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 134
• Issue: 7
• Pages: 2164-2168
• DOI: https://doi.org/10.1053/j.gastro.2008.04.013
• Public URL: https://nottingham-repository.worktribe.com/output/3181839
• Publisher URL: https://www.gastrojournal.org/article/S0016-5085(08)00664-1/fulltext?referrer=https%3A%2F%2Fwww.gastrojournal.org%2F