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Outputs (2235)

Phylogenetic insights into the terrestrial snails Helicoidei (Gastropoda: Stylommatophora) with special emphasis on the Camaenidae (2024)
Journal Article
Zhang, G., Naggs, F., Andrus, P. S., & Wade, C. M. (in press). Phylogenetic insights into the terrestrial snails Helicoidei (Gastropoda: Stylommatophora) with special emphasis on the Camaenidae. Zoological Journal of the Linnean Society, https://doi.org/10.1093/zoolinnean/zlae027

The superfamily Helicoidei are a widely distributed and diverse infraorder of land snails and slugs. Here, we constructed a phylogenetic tree based on sequences of the large subunit ribosomal RNA gene to investigate the relationships within the Helic... Read More about Phylogenetic insights into the terrestrial snails Helicoidei (Gastropoda: Stylommatophora) with special emphasis on the Camaenidae.

CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans (2024)
Journal Article
White, C. W., Platt, S., Kilpatrick, L. E., Dale, N., Abhayawardana, R. S., Dekkers, S., …Hill, S. J. (2024). CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans. Science Signaling, 17(828), Article abl3758. https://doi.org/10.1126/scisignal.abl3758

CXCL17 is a chemokine principally expressed by mucosal tissues, where it facilitates chemotaxis of monocytes, dendritic cells, and macrophages and has antimicrobial properties. CXCL17 is also implicated in the pathology of inflammatory disorders and... Read More about CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans.

Differentiation of Bulinussenegalensis and Bulinusforskalii Snails in West Africa Using Morphometric Analysis (2024)
Journal Article
Andrus, P. S., Joof, E., & Wade, C. M. (2024). Differentiation of Bulinussenegalensis and Bulinusforskalii Snails in West Africa Using Morphometric Analysis. Acta Parasitologica, https://doi.org/10.1007/s11686-024-00830-1

Purpose: Accurate identification of medically important intermediate host and vector species is crucial for understanding disease transmission and control. Identifying Bulinus snails which act as intermediate host species for the transmission of schi... Read More about Differentiation of Bulinussenegalensis and Bulinusforskalii Snails in West Africa Using Morphometric Analysis.

Characterising the stimulus-response function of mouse C-Low threshold mechanoreceptors to mechanical stimuliin vivo (2024)
Working Paper
Semizoglou, E., Lo Re, L., Middleton, S. J., Perez-Sanchez, J., Tufarelli, T., Bennett, D. L., & Chisholm, K. I. Characterising the stimulus-response function of mouse C-Low threshold mechanoreceptors to mechanical stimuliin vivo

C-low threshold mechanoreceptors (C-LTMRs) in animals (termed C-tactile (CT) fibres in humans) are a subgroup of C-fibre primary afferents, which innervate hairy skin and respond to low threshold punctate indentations and brush stimuli. These afferen... Read More about Characterising the stimulus-response function of mouse C-Low threshold mechanoreceptors to mechanical stimuliin vivo.

Sustained morphine exposure alters spinal NMDA receptor and astrocyte expression and exacerbates chronic pain behavior in female rats (2024)
Journal Article
Gonçalves, S. V., Woodhams, S. G., Li, L., Hathway, G. J., & Chapman, V. (2024). Sustained morphine exposure alters spinal NMDA receptor and astrocyte expression and exacerbates chronic pain behavior in female rats. PAIN Reports, 9(2), Article e1145. https://doi.org/10.1097/pr9.0000000000001145

IntroductionSustained opioid use has long-term negative impacts on future pain experience, particularly in women. This study aimed to investigate the underlying spinal neurobiology of this clinical observation in an experimental model of joint pain.O... Read More about Sustained morphine exposure alters spinal NMDA receptor and astrocyte expression and exacerbates chronic pain behavior in female rats.

Rising water temperature in rivers: Ecological impacts and future resilience (2024)
Journal Article
Johnson, M. F., Albertson, L. K., Algar, A. C., Dugdale, S. J., Edwards, P., England, J., …Wood, P. J. (2024). Rising water temperature in rivers: Ecological impacts and future resilience. Wiley Interdisciplinary Reviews: Water, Article e1724. https://doi.org/10.1002/wat2.1724

Rising water temperatures in rivers due to climate change are already having observable impacts on river ecosystems. Warming water has both direct and indirect impacts on aquatic life, and further aggravates pervasive issues such as eutrophication, p... Read More about Rising water temperature in rivers: Ecological impacts and future resilience.

Two novel species of arctic-alpine lichen-forming fungi (Ascomycota, Megasporaceae) from the Deosai Plains, Pakistan (2024)
Journal Article
Usman, M., Dyer, P. S., Brock, M., Wade, C. M., & Khalid, A. N. (2024). Two novel species of arctic-alpine lichen-forming fungi (Ascomycota, Megasporaceae) from the Deosai Plains, Pakistan. MycoKeys, 102, 285-299. https://doi.org/10.3897/mycokeys.102.113310

Members of the lichen-forming fungal genus Oxneriaria are known to occur in cold polar and high altitudinal environments. Two new species, Oxneriaria crittendenii and O. deosaiensis, are now described from the high altitude Deosai Plains, Pakistan, b... Read More about Two novel species of arctic-alpine lichen-forming fungi (Ascomycota, Megasporaceae) from the Deosai Plains, Pakistan.

A genomic toolkit for winged bean Psophocarpus tetragonolobus (2024)
Journal Article
Ho, W. K., Tanzi, A. S., Sang, F., Tsoutsoura, N., Shah, N., Moore, C., …Mayes, S. (2024). A genomic toolkit for winged bean Psophocarpus tetragonolobus. Nature Communications, 15(1), Article 1901. https://doi.org/10.1038/s41467-024-45048-x

A sustainable supply of plant protein is critical for future generations and needs to be achieved while reducing green house gas emissions from agriculture and increasing agricultural resilience in the face of climate volatility. Agricultural diversi... Read More about A genomic toolkit for winged bean Psophocarpus tetragonolobus.

Blood donation screening for hepatitis B virus core antibodies: The importance of confirmatory testing and initial implication for rare blood donor groups (2024)
Journal Article
Fu, M. X., Ingram, J., Roberts, C., Nurmi, V., Watkins, E., Dempsey, N., …Harvala, H. (2024). Blood donation screening for hepatitis B virus core antibodies: The importance of confirmatory testing and initial implication for rare blood donor groups. Vox Sanguinis, https://doi.org/10.1111/vox.13608

Background and Objectives Exclusion of blood donors with hepatitis B virus (HBV) core antibodies (anti-HBc) prevents transfusion-transmitted HBV infection but can lead to significant donor loss. As isolated anti-HBc positivity does not always indica... Read More about Blood donation screening for hepatitis B virus core antibodies: The importance of confirmatory testing and initial implication for rare blood donor groups.

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart (2024)
Journal Article
Waheed‐Ullah, Q., Wilsdon, A., Abbad, A., Rochette, S., Bu'Lock, F., Hitz, M., …Loughna, S. (2024). Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart. Journal of Anatomy, https://doi.org/10.1111/joa.14033

Congenital heart disease (CHD) is the most common congenital anomaly, with an overall incidence of approximately 1% in the United Kingdom. Exome sequencing in large CHD cohorts has been performed to provide insights into the genetic aetiology of CHD.... Read More about Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.