Outputs (4)

Peptide YY (PYY) And Neuromedin U (NMU): Effects On Ingestive Behavior (2006)
Book Chapter
Small, C. J., Jethwa, P. H., & Bloom, S. R. (2006). Peptide YY (PYY) And Neuromedin U (NMU): Effects On Ingestive Behavior. In A. J. Kastin (Ed.), Handbook of Biologically Active Peptides (945-952). Academic Press. https://doi.org/10.1016/B978-012369442-3/50132-X

This chapter discusses the effects of Neuromedin U (NMU) and Peptide YY (PYY) on ingestive behavior and their potential as anti-obesity agents. Many peptides are synthesized and released from the gastrointestinal (GI) tract and the central nervous sy... Read More about Peptide YY (PYY) And Neuromedin U (NMU): Effects On Ingestive Behavior.

Neuromedin U (NMU): Brain Peptide (2006)
Book Chapter
Jethwa, P. H., Small, C. J., & Bloom, S. R. (2006). Neuromedin U (NMU): Brain Peptide. In A. J. Kastin (Ed.), Handbook of Biologically Active Peptides (745-751). Academic Press. https://doi.org/10.1016/B978-012369442-3/50106-9

Neuromedin U (NMU) is one of the most abundant neuropeptides and has been found in significant concentrations in both the gastrointestinal (GI) tract and the central nervous system (CNS). There are two molecular forms of NMU; an icosapentapeptide (NM... Read More about Neuromedin U (NMU): Brain Peptide.

Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats (2006)
Journal Article
Thompson, E. L., Murphy, K. G., Patterson, M., Bewick, G. A., Stamp, G. W., Curtis, A. E., …Bloom, S. R. (2006). Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats. AJP - Endocrinology and Metabolism, 291(5), https://doi.org/10.1152/ajpendo.00040.2006

The kisspeptins are KiSS-1 gene-derived peptides that signal through the G protein-coupled receptor-54 (GPR54) and have recently been shown to be critical regulators of reproduction. Acute intracerebroventricular or peripheral administration of kissp... Read More about Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats.

Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat (2006)
Journal Article
Jethwa, P. H., Smith, K. L., Small, C. J., Abbott, C. R., Darch, S. J., Murphy, K. G., …Bloom, S. R. (2006). Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat. Endocrinology, 147(6), 2886-2892. https://doi.org/10.1210/en.2005-0983

Intracerebroventricular (ICV) administration of the hypothalamic neuropeptide neuromedin U (NMU) or the adipostat hormone leptin increases plasma ACTH and corticosterone. The relationship between leptin and NMU in the regulation of the hypothalamo-pi... Read More about Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat.