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Outputs (119)

Service dogs (2019)
Book Chapter
Harvey, N. (2019). Service dogs. In J. Vonk, & T. K. Shackelford (Eds.), Encyclopedia of Animal Cognition and Behavior

Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits (2019)
Journal Article
Tsoleridis, T., Chappell, J. G., Monchatre-Leroy, E., Umhang, G., Shi, M., Bennett, M., …Ball, J. K. (2019). Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits. Viruses, 12(1), Article 47. https://doi.org/10.3390/v12010047

The advent of unbiased metagenomic virus discovery has revolutionized studies of virus biodiversity and evolution. Despite this, our knowledge of the virosphere, including in mammalian species, remains limited. We used unbiased metagenomic sequencing... Read More about Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits.

Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys (2019)
Journal Article
El-Gendy, S. A., Alsafy, M. A., Rutland, C. S., EL-Khamary, A. N., Abu-Ahmed, H. M., & El-Kammar, M. H. (2020). Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys. Journal of Equine Veterinary Science, 88, Article 102904. https://doi.org/10.1016/j.jevs.2019.102904

The donkey is of socio-economic value yet imaging techniques in both healthy and abnormal limbs are a limiting factor in research and medicine. The objective was to determine anatomical features of both healthy and clinically abnormal donkey metacarp... Read More about Morphological and imaging evaluation of the metacarpophalangeal and metatarsophalangeal joints in healthy and lame donkeys.

Environmental and field characteristics associated with lameness in sheep: a study using a smartphone lameness app for data recording (2019)
Journal Article
Vittis, Y., & Kaler, J. (2019). Environmental and field characteristics associated with lameness in sheep: a study using a smartphone lameness app for data recording. Veterinary Record, https://doi.org/10.1136/vr.105476

Background: Sheep lameness is a major concern among farmers and policymakers with significant impacts on animal welfare standards as well as financial and production performance. The present study attempts to identify the relative importance of envir... Read More about Environmental and field characteristics associated with lameness in sheep: a study using a smartphone lameness app for data recording.

Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica (2019)
Journal Article
Elsheikha, H. M., Aziz, N., & Butt, A. (2020). Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica. Ecotoxicology and Environmental Safety, 190, Article 110054. https://doi.org/10.1016/j.ecoenv.2019.110054

© 2019 Elsevier Inc. Heavy metal exposure induces oxidative stress in terrestrial organisms, which they counteract via activation of antioxidant biomarkers. The present study investigated the effects of copper (Cu) and lead (Pb) on the total antioxid... Read More about Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica.

N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells (2019)
Journal Article
Abakir, A., Giles, T. C., Cristini, A., Foster, J. M., Dai, N., Starczak, M., …Ruzov, A. (2020). N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells. Nature Genetics, 52(1), 48-55. https://doi.org/10.1038/s41588-019-0549-x

© 2019, The Author(s), under exclusive licence to Springer Nature America, Inc. R-loops are nucleic acid structures formed by an RNA:DNA hybrid and unpaired single-stranded DNA that represent a source of genomic instability in mammalian cells1–4. Her... Read More about N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.

Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes (2019)
Journal Article
Aziz, N., Butt, A., & Elsheikha, H. M. (2020). Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes. Environmental Science and Pollution Research, 27, 3309–3319. https://doi.org/10.1007/s11356-019-07055-0

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Major concerns exist regarding the environmental and human health risks caused by exposure to heavy metals. Spiders are often used as a model in ecotoxicological studies to assess soil po... Read More about Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes.

Veterinary use of bacteriophage therapy in intensively-reared livestock (2019)
Journal Article
Gigante, A., & Atterbury, R. J. (2019). Veterinary use of bacteriophage therapy in intensively-reared livestock. Virology Journal, 16(1), Article 155. https://doi.org/10.1186/s12985-019-1260-3

Zoonoses are infectious diseases transmitted directly or indirectly between animals and humans. Several important zoonotic pathogens colonize farm animals asymptomatically, which may lead to contamination of the food chain and public health hazards.... Read More about Veterinary use of bacteriophage therapy in intensively-reared livestock.

Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia (2019)
Journal Article
Parry, H. M., Mirajkar, N., Cutmore, N., Zuo, J., Long, H., Kwok, M., …Moss, P. (2019). Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia. Frontiers in Immunology, 10, 1-7. https://doi.org/10.3389/fimmu.2019.02832

Chronic Lymphocytic Leukaemia (CLL) is associated with immune suppression and susceptibility to infection. CD8+ T cell numbers are increased and demonstrate elevated expression of PD-1 and impaired function. The mechanisms driving these features of e... Read More about Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia.

The ‘dark matter’ of ubiquitin-mediated processes: opportunities and challenges in the identification of ubiquitin-binding domains (2019)
Journal Article
Radley, E., Long, J., Gough, K., & Layfield, R. (2019). The ‘dark matter’ of ubiquitin-mediated processes: opportunities and challenges in the identification of ubiquitin-binding domains. Biochemical Society Transactions, 47(6), 1949-1962. https://doi.org/10.1042/bst20190869

Ubiquitin modifications of target proteins act to localise, direct and specify a diverse range of cellular processes, many of which are biomedically relevant. To allow this diversity, ubiquitin modifications exhibit remarkable complexity, determined... Read More about The ‘dark matter’ of ubiquitin-mediated processes: opportunities and challenges in the identification of ubiquitin-binding domains.