Outputs (174)

Relative efficacy of different types of exercise for treatment of knee and hip osteoarthritis: Protocol for network meta-analysis of randomised controlled trials (2016)
Journal Article
Goh, S., Persson, M., Bhattacharya, A., Hall, M. C., Doherty, M., & Zhang, W. (2016). Relative efficacy of different types of exercise for treatment of knee and hip osteoarthritis: Protocol for network meta-analysis of randomised controlled trials. Systematic Reviews, 5(147), https://doi.org/10.1186/s13643-016-0321-6

Background: “Exercise” is universally recommended as a core treatment for knee and hip osteoarthritis (OA). However, there are very few head-to-head comparative trials to determine the relative efficacy between different types of exercise. The aim of... Read More about Relative efficacy of different types of exercise for treatment of knee and hip osteoarthritis: Protocol for network meta-analysis of randomised controlled trials.

Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches (2016)
Journal Article
Onyido, E. K., Sweeney, E., & Nateri, A. S. (2016). Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches. Molecular Cancer, 15(56), https://doi.org/10.1186/s12943-016-0541-3

Over the past few years, microRNAs (miRNAs) have not only emerged as integral regulators of gene expression at the post-transcriptional level but also respond to signalling molecules to affect cell function(s). miRNAs crosstalk with a variety of the... Read More about Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches.

Qualitative exploration of the benefits of group-based memory rehabilitation for people with neurological disabilities: implications for rehabilitation delivery and evaluation (2016)
Journal Article
Chouliara, N., & Lincoln, N. (2016). Qualitative exploration of the benefits of group-based memory rehabilitation for people with neurological disabilities: implications for rehabilitation delivery and evaluation. BMJ Open, 6(9), 1-11. https://doi.org/10.1136/bmjopen-2016-011225

Objective: To identify patient-perceived benefits of memory rehabilitation and draw transferrable lessons for the delivery and evaluation of similar interventions for people with neurological disabilities.

Methods: A qualitative study was conducte... Read More about Qualitative exploration of the benefits of group-based memory rehabilitation for people with neurological disabilities: implications for rehabilitation delivery and evaluation.

Heritability of non-speech auditory processing skills (2016)
Journal Article
Brewer, C. C., Zalewski, C. K., King, K. A., Zobay, O., Riley, A., Ferguson, M. A., …Moore, D. R. (2016). Heritability of non-speech auditory processing skills. European Journal of Human Genetics, 24(8), https://doi.org/10.1038/ejhg.2015.277

Recent insight into the genetic bases for autism spectrum disorder, dyslexia, stuttering, and language disorders suggest that neurogenetic approaches may also reveal at least one etiology of auditory processing disorder (APD). A person with an APD ty... Read More about Heritability of non-speech auditory processing skills.

The Human Connectome Project's neuroimaging approach (2016)
Journal Article
Glasser, M. F., Smith, S. M., Marcus, D. S., Andersson, J. L., Auerbach, E. J., Behrens, T. E., …Van Essen, D. C. (2016). The Human Connectome Project's neuroimaging approach. Nature Neuroscience, 19(9), https://doi.org/10.1038/nn.4361

Noninvasive human neuroimaging has yielded many discoveries about the brain. Numerous methodological advances have also occurred, though inertia has slowed their adoption. This paper presents an integrated approach to data acquisition, analysis and s... Read More about The Human Connectome Project's neuroimaging approach.

Hearing instruments for unilateral severe-to-profound sensorineural hearing loss in adults (2016)
Journal Article
Kitterick, P. T., Smith, S. N., & Lucas, L. (2016). Hearing instruments for unilateral severe-to-profound sensorineural hearing loss in adults. Ear and Hearing, 37(5), https://doi.org/10.1097/AUD.0000000000000313

Objectives: A systematic review of the literature and meta-analysis was conducted to assess the nature and quality of the evidence for the use of hearing instruments in adults with a unilateral severe-to-profound sensorineural hearing loss.
Design:... Read More about Hearing instruments for unilateral severe-to-profound sensorineural hearing loss in adults.

Expression and regulation of immune-modulatory enzyme Indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation (2016)
Journal Article
Aldajani, W. A., Salazar, F., Sewell, H. F., Knox, A., & Ghaemmaghami, A. M. (2016). Expression and regulation of immune-modulatory enzyme Indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation. Oncotarget, 7(36), https://doi.org/10.18632/oncotarget.11586

Indoleamine 2,3-dioxygenase (IDO) catalyzes the degradation of tryptophan, which plays a critical role in immune suppression through regulating the production of a series of metabolites that are generally referred to as kynurenines. It has become inc... Read More about Expression and regulation of immune-modulatory enzyme Indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation.

Effect of contralateral medial olivocochlear feedback on perceptual estimates of cochlear gain and compression (2016)
Journal Article
Fletcher, M. D., Krumbholz, K., & de Boer, J. (2016). Effect of contralateral medial olivocochlear feedback on perceptual estimates of cochlear gain and compression. Journal of the Association for Research in Otolaryngology, 17(6), 559-575. https://doi.org/10.1007/s10162-016-0574-8

The active cochlear mechanism amplifies responses to low-intensity sounds, compresses the range of input sound intensities to a smaller output range, and increases cochlear frequency selectivity. The gain of the active mechanism can be modulated by t... Read More about Effect of contralateral medial olivocochlear feedback on perceptual estimates of cochlear gain and compression.

What is the evidence-base for atopic eczema treatments? A summary of published randomised controlled trials (2016)
Journal Article
Nankervis, H., Thomas, K., Delamere, F. M., Barbarot, S., Smith, S., Rogers, N. K., & Williams, H. C. (in press). What is the evidence-base for atopic eczema treatments? A summary of published randomised controlled trials. British Journal of Dermatology, 176(4), https://doi.org/10.1111/bjd.14999

Atopic eczema (AE) is a common chronic inflammatory skin condition. Whilst many AE treatment options are available, the evidence to support their efficacy varies in depth and quality. In 2000, an NIHR HTA systematic review identified and evaluated ex... Read More about What is the evidence-base for atopic eczema treatments? A summary of published randomised controlled trials.

Running and knee osteoarthritis: a systematic review and meta-analysis (2016)
Journal Article
Timmins, K. A., Batt, M. E., & Edwards, K. L. (2017). Running and knee osteoarthritis: a systematic review and meta-analysis. American Journal of Sports Medicine, 45(6), https://doi.org/10.1177/0363546516657531

Background:
Osteoarthritis (OA) is a chronic condition characterized by pain, impaired function, and reduced quality of life. A number of risk factors for knee OA have been identified, such as obesity, occupation, and injury. The association between... Read More about Running and knee osteoarthritis: a systematic review and meta-analysis.