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Outputs (174)

Scoping systematic review of treatments for eczema (2016)
Journal Article
Nankervis, H., Thomas, K., Delamere, F. M., Barbarot, S., Rogers, N. K., & Williams, H. C. (2016). Scoping systematic review of treatments for eczema. Programme Grants for Applied Research, 4(7), https://doi.org/10.3310/pgfar04070

Background: Eczema is a very common chronic inflammatory skin condition.
Objectives: To update the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) systematic review of treatments for atopic eczema, published in 2000,... Read More about Scoping systematic review of treatments for eczema.

Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men (2016)
Journal Article
Atherton, P. J., Kumar, V., Selby, A. L., Rankin, D., Hildebrandt, W., Phillips, B. E., Williams, J. P., Hiscock, N., & Smith, K. (2017). Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men. Clinical Nutrition, 36(3), 888-895. https://doi.org/10.1016/j.clnu.2016.04.025

Maximizing anabolic responses to feeding and exercise is crucial for muscle maintenance and adaptation to exercise training. We hypothesized that enriching a protein drink with leucine would improve anabolic responses to resistance exercise (RE: 6×8... Read More about Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men.

Development and clinical acceptability of a pre-operative risk stratification tool of cerebellar mutism syndrome in children with posterior fossa tumour (2016)
Presentation / Conference Contribution
Dineen, R. A., Avula, S., Chambers, T., Dutta, M., Liu, J., Soria, D., …Walker, D. (2016). Development and clinical acceptability of a pre-operative risk stratification tool of cerebellar mutism syndrome in children with posterior fossa tumour.

Aims: Despite identification of numerous pre-operative cerebellar mutism syndrome (CMS) clinical and radiological predictors, a unifying pre-operative risk stratification model for use during surgical consent is currently lacking. The aims of the pro... Read More about Development and clinical acceptability of a pre-operative risk stratification tool of cerebellar mutism syndrome in children with posterior fossa tumour.

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing (2016)
Journal Article
Dhami, S. P. S., Kappala, S. S., Thompson, A., & Szegezdi, E. (in press). Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing. Drug Discovery Today, 21(9), https://doi.org/10.1016/j.drudis.2016.04.019

Acute myeloid leukaemia (AML) is a hierarchically structured malignancy in which aberrant leukemic stem cells drive the production of leukaemic blast cell clones. AML cells strictly depend on the bone marrow microenvironment (BMM) in which they resid... Read More about Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing.

Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer (2016)
Journal Article
Green, A. R., Soria, D., Powe, D. G., Nolan, C. C., Aleskandarany, M. A., Szász, M., …Ellis, I. O. (2016). Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer. Breast Cancer Research and Treatment, 157(1), 65-75. https://doi.org/10.1007/s10549-016-3804-1

The Nottingham prognostic index plus (NPI+) is based on the assessment of biological class combined with established clinicopathologic prognostic variables providing improved patient outcome stratification for breast cancer superior to the traditiona... Read More about Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer.

Choosing which ear to implant in adult candidates with functional residual hearing (2016)
Journal Article
Fielden, C. A., Mehta, R. L., & Kitterick, P. T. (in press). Choosing which ear to implant in adult candidates with functional residual hearing. Cochlear Implants International, 17(sup1), https://doi.org/10.1080/14670100.2016.1155805

This study examined whether audiologists consider the potential benefits of contralateral hearing aid use following cochlear implantation when recommending which ear to implant in UK adult candidates with residual hearing. Thirty-four audiologists fr... Read More about Choosing which ear to implant in adult candidates with functional residual hearing.

Predicting speech perception outcomes following cochlear implantation in adults with unilateral deafness or highly asymmetric hearing loss (2016)
Journal Article
Kitterick, P. T., & Lucas, L. (in press). Predicting speech perception outcomes following cochlear implantation in adults with unilateral deafness or highly asymmetric hearing loss. Cochlear Implants International, 17(sup 1), https://doi.org/10.1080/14670100.2016.1155806

Unilateral deafness and highly-asymmetric hearing loss can impair listening abilities in everyday situations, create substantial audiological handicap, and reduce overall quality of life. Preliminary evidence from early-phase studies in adults sugges... Read More about Predicting speech perception outcomes following cochlear implantation in adults with unilateral deafness or highly asymmetric hearing loss.

Preliminary assessment of the feasibility of using AB words to assess candidacy in adults (2016)
Journal Article
Vickers, D. A., Riley, A., Ricaud, R., Verschuur, C., Cooper, S., Nunn, T., …Kitterick, P. T. (in press). Preliminary assessment of the feasibility of using AB words to assess candidacy in adults. Cochlear Implants International, 17(sup 1), https://doi.org/10.1080/14670100.2016.1161143

Background: Adult cochlear implant (CI) candidacy is assessed in part by the use of speech perception measures. In the United Kingdom the current cut-off point to fall within the CI candidacy range is a score of less than 50% on the BKB sentences pre... Read More about Preliminary assessment of the feasibility of using AB words to assess candidacy in adults.

Access to aidable residual hearing in adult candidates for cochlear implantation in the UK (2016)
Journal Article
Fielden, C. A., Hampton, R., Smith, S., & Kitterick, P. T. (in press). Access to aidable residual hearing in adult candidates for cochlear implantation in the UK. Cochlear Implants International, 17(sup 1), https://doi.org/10.1080/14670100.2016.1153836

Guidance from the National Institute for Health and Care Excellence (NICE) permits candidates to receive a cochlear implant provided they only hear sounds louder than 90 dB HL at 2 and 4 kHz. In some patients, their level of residual hearing may be s... Read More about Access to aidable residual hearing in adult candidates for cochlear implantation in the UK.