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Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells (2015)
Journal Article
Sidney, L. E., McIntosh, O. D., & Hopkinson, A. (2015). Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells. Investigative Ophthalmology & Visual Science, 56(12), https://doi.org/10.1167/iovs.15-17810

Purpose: Cells of the corneal epithelium and stroma can be distinguished in vivo by different intermediate filaments, cytokeratins for corneal epithelial cells (CEC) and vimentin for keratocytes. Isolated and cultured keratocytes change phenotype, lo... Read More about Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells.

Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform (2015)
Journal Article
Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S., George, V., Kalra, S., …Young, L. E. (2016). Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform. BBA - Biochimica et Biophysica Acta, 1863(7), https://doi.org/10.1016/j.bbamcr.2015.10.014

Cardiomyocytes from human pluripotent stem cells (hPSCs-CMs) could revolutionise biomedicine. Global burden of heart failure will soon reach USD $90bn, while unexpected cardiotoxicity underlies 28% of drug withdrawals. Advances in hPSC isolation, Cas... Read More about Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform.

Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma (2015)
Journal Article
Lilburn, D. M., Tatler, A. L., Six, J. S., Lesbats, C., Habgood, A., Porte, J., …Meersmann, T. (2015). Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma. Magnetic Resonance in Medicine, 76(4), 1224-1235. https://doi.org/10.1002/mrm.26003

© 2015 The Authors. Wiley Periodicals, Inc. Purpose: Asthma is a disease of increasing worldwide importance that calls for new investigative methods. Ex vivo lung tissue is being increasingly used to study functional respiratory parameters independen... Read More about Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma.

Measuring macroscopic brain connections in vivo (2015)
Journal Article
Jbabdi, S., Sotiropoulos, S. N., Haber, S. N., Van Essen, D. C., & Behrens, T. E. (2015). Measuring macroscopic brain connections in vivo. Nature Neuroscience, 18(11), https://doi.org/10.1038/nn.4134

Decades of detailed anatomical tracer studies in non-human animals point to a rich and complex organization of long-range white matter connections in the brain. State-of-the art in vivo imaging techniques are striving to achieve a similar level of de... Read More about Measuring macroscopic brain connections in vivo.

Nottingham Prognostic Index Plus: validation of a clinical decision making tool in breast cancer in an independent series (2015)
Journal Article
Green, A. R., Soria, D., Stephen, J., Powe, D. G., Nolan, C. C., Kunkler, I., Thomas, J., Kerr, G. R., Jack, W., Cameron, D., Piper, T., Ball, G. R., Garibaldi, J. M., Rakha, E., Bartlett, J. M., & Ellis, I. O. (2016). Nottingham Prognostic Index Plus: validation of a clinical decision making tool in breast cancer in an independent series. Journal of Pathology: Clinical Research, 2, https://doi.org/10.1002/cjp2.32

The Nottingham Prognostic Index Plus (NPI+)is a clinical decision making tool in breast cancer (BC) that aims to provide improved patient outcome stratification superior to the traditional NPI. This study aimed to validate the NPI+ in an independent... Read More about Nottingham Prognostic Index Plus: validation of a clinical decision making tool in breast cancer in an independent series.

How does auditory training work? Joined up thinking and listening (2015)
Journal Article
Ferguson, M. A., & Henshaw, H. (in press). How does auditory training work? Joined up thinking and listening. Seminars in Hearing, 36(4), https://doi.org/10.1055/s-0035-1568985

Auditory training aims to compensate for degradation in the auditory signal and is offered as an intervention to help alleviate the most common complaint in people with hearing loss, understanding speech in a background noise. Yet there remain many u... Read More about How does auditory training work? Joined up thinking and listening.

An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging (2015)
Journal Article
Andersson, J. L., & Sotiropoulos, S. N. (2016). An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. NeuroImage, 125, https://doi.org/10.1016/j.neuroimage.2015.10.019

In this paper we describe a method for retrospective estimation and correction of eddy current (EC)-induced distortions and subject movement in diffusion imaging. In addition a susceptibility-induced field can be supplied and will be incorporated int... Read More about An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging.

Hyperacusis Questionnaire as a Tool for Measuring Hypersensitivity to Sound in a Tinnitus Research Population (2015)
Journal Article
Fackrell, K., Fearnley, C., Hoare, D. J., & Sereda, M. (2015). Hyperacusis Questionnaire as a Tool for Measuring Hypersensitivity to Sound in a Tinnitus Research Population. BioMed Research International, 2015, 1-12. https://doi.org/10.1155/2015/290425

Hypersensitivity to external sounds is often comorbid with tinnitus and may be significant for adherence to certain types of tinnitus management. Therefore, a clear measure of sensitivity to sound is important. The aim of this study was to evaluate t... Read More about Hyperacusis Questionnaire as a Tool for Measuring Hypersensitivity to Sound in a Tinnitus Research Population.

The feasibility of psychomotor therapy in acute mental health services for adults with intellectual disability (2015)
Journal Article
Kay, J. J., Clegg, J. A., Emck, C., & Standen, P. J. (2016). The feasibility of psychomotor therapy in acute mental health services for adults with intellectual disability. Journal of Intellectual and Developmental Disability, 41(1), 54-60. https://doi.org/10.3109/13668250.2015.1094037

Background. Psychomotor therapy enables people to reflect on the relationship between experiences and feelings by starting from awareness of bodily responses rather than from awareness of emotion. In this study we examine PsyMot (ID), an assessment t... Read More about The feasibility of psychomotor therapy in acute mental health services for adults with intellectual disability.