Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition
(2021)
Journal Article
Steketee, P. C., Dickie, E. A., Iremonger, J., Crouch, K., Paxton, E., Jayaraman, S., Alfituri, O. A., Awuah-Mensah, G., Ritchie, R., Schnaufer, A., Rowan, T., de Koning, H. P., Gadelha, C., Wickstead, B., Barrett, M. P., & Morrison, L. J. (2021). Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition. PLoS Pathogens, 17(7), Article e1009734. https://doi.org/10.1371/journal.ppat.1009734
Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma congolense. In comparison to the well-studied T. brucei, there is a major paucit... Read More about Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.