Professor Ruman Rahman's Outputs (2)

Evolution of Preclinical Models for Glioblastoma Modelling and Drug Screening (2025)
Journal Article
Thomas, G., & Rahman, R. (2025). Evolution of Preclinical Models for Glioblastoma Modelling and Drug Screening. Current Oncology Reports, https://doi.org/10.1007/s11912-025-01672-4

Purpose of Review

Isocitrate dehydrogenase wild-type glioblastoma is an extremely aggressive and fatal primary brain tumour, characterised by extensive heterogeneity and diffuse infiltration of brain parenchyma. Despite multimodal treatment and di... Read More about Evolution of Preclinical Models for Glioblastoma Modelling and Drug Screening.

Pentablock thermoresponsive hydrogels for chemotherapeutic delivery in a pancreatic cancer model (2025)
Journal Article
Elsherbeny, A., Bayraltutan, H., Gumus, N., McCrorie, P., Garcia-Sampedro, A., Parmar, S., Ritchie, A., Meakin, M., Oz, U. C., Rahman, R., Ashworth, J. C., Grabowska, A. M., Moloney, C., & Alexander, C. (2025). Pentablock thermoresponsive hydrogels for chemotherapeutic delivery in a pancreatic cancer model. Biomaterials Science, 13(7), 1831-1848. https://doi.org/10.1039/d4bm01629g

The design of biodegradable and thermoresponsive polymeric hydrogels with tuneable properties holds immense promise for localised and sustained drug delivery. In this study, we designed and synthesised a library of novel pentablock copolymers, incorp... Read More about Pentablock thermoresponsive hydrogels for chemotherapeutic delivery in a pancreatic cancer model.