Professor CAMERON ALEXANDER's Outputs (2)

Redox-responsive micellar-like nanoparticles can overcome intrinsic multi-drug resistance in tumour spheroids of triple negative breast cancer (2025)
Journal Article
Monteiro, C. J., Monteiro, P. F., Travanut, A., Gulfam, M., Heery, D. M., Grabowska, A., & Alexander, C. (in press). Redox-responsive micellar-like nanoparticles can overcome intrinsic multi-drug resistance in tumour spheroids of triple negative breast cancer. RSC Pharmaceutics,

Triple negative breast cancer (TNBC) is one of the most difficult subtypes of breast cancer to treat, due its aggressiveness, high heterogeneity and lack of targeted therapies. Efforts have been made to elucidate the mechanisms by which TNBC cells be... Read More about Redox-responsive micellar-like nanoparticles can overcome intrinsic multi-drug resistance in tumour spheroids of triple negative breast cancer.

Pentablock thermoresponsive hydrogels for chemotherapeutic delivery in a pancreatic cancer model (2025)
Journal Article
Elsherbeny, A., Bayraltutan, H., Gumus, N., McCrorie, P., Garcia-Sampedro, A., Parmar, S., Ritchie, A., Meakin, M., Oz, U. C., Rahman, R., Ashworth, J. C., Grabowska, A. M., Moloney, C., & Alexander, C. (2025). Pentablock thermoresponsive hydrogels for chemotherapeutic delivery in a pancreatic cancer model. Biomaterials Science, https://doi.org/10.1039/d4bm01629g

The design of biodegradable and thermoresponsive polymeric hydrogels with tuneable properties holds immense promise for localised and sustained drug delivery. In this study, we designed and synthesised a library of novel pentablock copolymers, incorp... Read More about Pentablock thermoresponsive hydrogels for chemotherapeutic delivery in a pancreatic cancer model.