All Outputs (45066)

Natural product pharmacology: the British Journal of Pharmacology perspective (2024)
Journal Article
Wang, X., Izzo, A. A., Papapetropoulos, A., Alexander, S. P. H., Cortese‐Krott, M., Kendall, D. A., Martemyanov, K. A., Mauro, C., Panettieri, R. A., Patel, H. H., Schulz, R., Stefanska, B., Stephens, G. J., Teixeira, M. M., Vergnolle, N., & Ferdinandy, P. (2024). Natural product pharmacology: the British Journal of Pharmacology perspective. British Journal of Pharmacology, https://doi.org/10.1111/bph.17300

Natural products (NPs) have long been used as a rich source of bioactive compounds for drug development. Recent technological advancements have revitalised natural products research as evidenced by increased publications in this field. In this editor... Read More about Natural product pharmacology: the British Journal of Pharmacology perspective.

‘The Song of the Innuit’: Circulating Arctic ethnographic knowledge through verse (2024)
Journal Article
Martin, P. R. (2024). ‘The Song of the Innuit’: Circulating Arctic ethnographic knowledge through verse. cultural geographies, https://doi.org/10.1177/14744740241269142

This article seeks to advance recent literatures exploring the important role of poetry in the production and circulation of geographical knowledge. It does this by critically analysing a poem that was written by the traveller and scholar Wiliam Heal... Read More about ‘The Song of the Innuit’: Circulating Arctic ethnographic knowledge through verse.

The role of the ALKBH5 RNA demethylase in invasive breast cancer (2024)
Journal Article
Woodcock, C. L., Alsaleem, M., Toss, M. S., Lothion-Roy, J., Harris, A. E., Jeyapalan, J. N., Blatt, N., Rizvanov, A. A., Miftakhova, R. R., Kariri, Y. A., Madhusudan, S., Green, A. R., Rutland, C. S., Fray, R. G., Rakha, E. A., & Mongan, N. P. (2024). The role of the ALKBH5 RNA demethylase in invasive breast cancer. Discover Oncology, 15(1), Article 343. https://doi.org/10.1007/s12672-024-01205-8

Background: N6-methyladenosine (m6A) is the most common internal RNA modification and is involved in regulation of RNA and protein expression. AlkB family member 5 (ALKBH5) is a m6A demethylase. Given the important role of m6A in biological mechanism... Read More about The role of the ALKBH5 RNA demethylase in invasive breast cancer.

Dual impacts of hydrology and damming on eutrophication: Comparison of two Ramsar wetlands in the middle Yangtze floodplain (2024)
Journal Article
Zeng, L., Engels, S., Swann, G. E., Chen, X., Huang, X., Cao, Y., & McGowan, S. (2024). Dual impacts of hydrology and damming on eutrophication: Comparison of two Ramsar wetlands in the middle Yangtze floodplain. Journal of Hydrology, 641, Article 131839. https://doi.org/10.1016/j.jhydrol.2024.131839

Dam construction for social-economic benefits has raised substantial biological and ecological concerns. However, contrasting findings have been reported regarding the role of hydrological modification in floodplain lake ecosystems. Here, we evaluate... Read More about Dual impacts of hydrology and damming on eutrophication: Comparison of two Ramsar wetlands in the middle Yangtze floodplain.

Paving the road while walking -perspectives from Flexible Assertive Community Treatment managers on preparing the implementation of peer support work in Outpatient Services (2024)
Journal Article
Johansen, K. K., Lerbaek, B., Slade, M., Castelein, S., & Jørgensen, R. (in press). Paving the road while walking -perspectives from Flexible Assertive Community Treatment managers on preparing the implementation of peer support work in Outpatient Services. Issues in Mental Health Nursing,

This qualitative study explored the perspectives of Flexible Assertive Community Treatment managers on preparation and employment of peer support workers. The study was based on semi-structured interviews with managers (n = 5) in Outpatient Services... Read More about Paving the road while walking -perspectives from Flexible Assertive Community Treatment managers on preparing the implementation of peer support work in Outpatient Services.

Proactive integrated consultation-liaison psychiatry and time spent in hospital by older medical inpatients in England (The HOME Study): a multicentre, parallel-group, randomised controlled trial (2024)
Journal Article
Sharpe, M., Walker, J., van Niekerk, M., Toynbee, M., Magill, N., Frost, C., White, I. R., Walker, S., Duarte, A., Owens, C., Dickens, C., Price, A., Sharpe, M., Walker, J., van Niekerk, M., Toynbee, M., Magill, N., Frost, C., White, I. R., Walker, S., …Yousif, M. (2024). Proactive integrated consultation-liaison psychiatry and time spent in hospital by older medical inpatients in England (The HOME Study): a multicentre, parallel-group, randomised controlled trial. Lancet Psychiatry, 11(9), 684-695. https://doi.org/10.1016/s2215-0366%2824%2900188-3

Background: Older people admitted to hospital in an emergency often have prolonged inpatient stays that worsen their outcomes, increase health-care costs, and reduce bed availability. Growing evidence suggests that the biopsychosocial complexity of t... Read More about Proactive integrated consultation-liaison psychiatry and time spent in hospital by older medical inpatients in England (The HOME Study): a multicentre, parallel-group, randomised controlled trial.

Do neuroticism and efficacy beliefs moderate the relationship between climate change worry and mental wellbeing? (2024)
Journal Article
Ogunbode, C. A., Salmela-Aro, K., Maran, D. A., van den Broek, K., Doran, R., Lins, S., Torres-Marín, J., Navarro-Carrillo, G., Rocchi, G., & Schermer, J. A. (2024). Do neuroticism and efficacy beliefs moderate the relationship between climate change worry and mental wellbeing?. Journal of Affective Disorders, 364, 37-40. https://doi.org/10.1016/j.jad.2024.08.018

Background: Research on the nature and prevalence of phenomena like climate anxiety (or eco-anxiety) is increasing rapidly but there is little understanding of the conditions under which climate change worry becomes more or less likely to significant... Read More about Do neuroticism and efficacy beliefs moderate the relationship between climate change worry and mental wellbeing?.

Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data (2024)
Journal Article
CIPOLLETTA, E., Nakafero, G., McCormick, N., Yokose, C., Avery, A., Mamas, M., Choi, H., Tata, L., & Abhishek, A. (in press). Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data. The Lancet Rheumatology,

Background Starting urate-lowering therapy (ULT) may trigger gout flares. Gout flares have been temporally associated with an increased risk of cardiovascular events (CVEs).
Objective To estimate the risk of CVEs among patients with gout initiating... Read More about Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data.

Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance (2024)
Journal Article
Heydon, J., Chakraborty, R., Patel, V., Wood, C., Wood, M., & Bunce, C. (2024). Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance. Environmental Management, https://doi.org/10.1007/s00267-024-02014-z

Domestic combustion emissions pose a growing risk to public health, especially in the UK. Existing responses are polarised, with government advocating use of lower emission fuels and stoves while clean air campaigners call for blanket bans on burning... Read More about Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance.

Conversion of high moisture biomass to hierarchical porous carbon via molten base carbonisation and activation for electrochemical double layer capacitor (2024)
Journal Article
Egun, I. L., Akinwolemiwa, B., Yin, B., Tian, H., He, H., Fow, K. L., Zhang, H., Chen, G. Z., & Hu, D. (2024). Conversion of high moisture biomass to hierarchical porous carbon via molten base carbonisation and activation for electrochemical double layer capacitor. Bioresource Technology, 409, 131251. https://doi.org/10.1016/j.biortech.2024.131251

Biomass-derived carbon for supercapacitors faces the challenge of achieving hierarchical porous carbon with graphitic structure and specific heteroatoms through a single-stage thermal process that minimises resource input. Herein, molten base carboni... Read More about Conversion of high moisture biomass to hierarchical porous carbon via molten base carbonisation and activation for electrochemical double layer capacitor.

2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy (2024)
Journal Article
Das, S., McIvor, C., Greener, A., Suwita, C., Argent, S. P., & O'Duill, M. L. (2024). 2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy. Angewandte Chemie, https://doi.org/10.1002/anie.202410954

The 2,2-difluoroethyl group is an important lipophilic hydrogen bond donor in medicinal chemistry, but its incorporation into small molecules is often challenging. Herein, we demonstrate electrophilic 2,2-difluoroethylation of thiol, amine and alcoho... Read More about 2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy.

Synergistic state governance of labour standards in global value chains: Forced labour in the Malaysia–Nepal–UK medical gloves supply chain (2024)
Journal Article
Brown, J. A., Hughes, A., Bhutta, M. F., Trautrims, A., & Trueba, M. L. (2024). Synergistic state governance of labour standards in global value chains: Forced labour in the Malaysia–Nepal–UK medical gloves supply chain. Competition and Change, https://doi.org/10.1177/10245294241272190

Drawing on research into medical gloves global value chains (GVCs), this article examines the interacting roles that states differently positioned in GVCs have played in preventing and eliminating forced labour. Our case study, based on a worker surv... Read More about Synergistic state governance of labour standards in global value chains: Forced labour in the Malaysia–Nepal–UK medical gloves supply chain.

Bringing the voice of social housing tenants into shaping the health and care research agenda (2024)
Journal Article
Phillips, O. R., Mardell, D., Stephenson, K., Hussain, S., Burton, D., Bernard, B., Stevenson, S., & Morling, J. R. (2024). Bringing the voice of social housing tenants into shaping the health and care research agenda. Research Involvement and Engagement, 10, Article 85. https://doi.org/10.1186/s40900-024-00613-y

Background: A larger percentage of social housing tenants have poorer physical and mental health outcomes compared to private renters and homeowners. They are also at a greater risk of respiratory conditions, cardiovascular disease, communicable dise... Read More about Bringing the voice of social housing tenants into shaping the health and care research agenda.

Understanding how nurses can effectively utilise social media for increasing public involvement, recruitment, and impact dissemination of Clinical Research Trials (2024)
Journal Article
Jackson, J., Moreton, J., Barnett, N., & Hurst, M. (2024). Understanding how nurses can effectively utilise social media for increasing public involvement, recruitment, and impact dissemination of Clinical Research Trials. Journal of Research in Nursing,

Background
The methodologies for clinical research trials are evolving to greater usage of social media platforms, providing opportunities to incorporate smart technologies in their delivery. Research Nurses should consider how they can utilise pla... Read More about Understanding how nurses can effectively utilise social media for increasing public involvement, recruitment, and impact dissemination of Clinical Research Trials.

Comparing self-perceptions, meta-perceptions, and peer judgments of the academic experience of autistic and non-autistic university students (2024)
Journal Article
Alhusayni, A., Sheppard, E., & Marsh, L. (in press). Comparing self-perceptions, meta-perceptions, and peer judgments of the academic experience of autistic and non-autistic university students. Autism in Adulthood,

Background. Previous research has shown that, when presented with brief samples of behaviour, non-autistic university students judge autistic peers less favourably than non-autistic peers on measures of academic experience (e.g. motivation to study,... Read More about Comparing self-perceptions, meta-perceptions, and peer judgments of the academic experience of autistic and non-autistic university students.

Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement (2024)
Journal Article
Ball, J. D., Hills, E., Altaf, A., Ramesh, P., Green, M., Surti, F. B., Minhas, J. S., Robinson, T. G., Bond, B., Lester, A., Hoiland, R., Klein, T., Liu, J., Nasr, N., Junejo, R. T., Müller, M., Lecchini-Visintini, A., Mitsis, G., Burma, J. S., Smirl, J. D., …Beishon, L. . C. (2024). Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement. Journal of Cerebral Blood Flow and Metabolism, https://doi.org/10.1177/0271678x241270452

Neurovascular coupling (NVC) is the perturbation of cerebral blood flow (CBF) to meet varying metabolic demands induced by various levels of neural activity. NVC may be assessed by Transcranial Doppler ultrasonography (TCD), using task activation pro... Read More about Neurovascular coupling methods in healthy individuals using transcranial doppler ultrasonography: A systematic review and consensus agreement.

Pollutant cross-transmission in courtyard buildings: Wind tunnel experiments and computational fluid dynamics (CFD) evaluation (2024)
Journal Article
Sun, H., Owen, J. S., Almazmumi, S., Liu, C., Mohammadi, M., Dik, A., Jimenez-Bescos, C., & Calautit, J. K. (2024). Pollutant cross-transmission in courtyard buildings: Wind tunnel experiments and computational fluid dynamics (CFD) evaluation. Building and Environment, 264, Article 111919. https://doi.org/10.1016/j.buildenv.2024.111919

Courtyards, a historical architectural feature surrounded by buildings, are common in urban housing and residential complexes. These spaces, often open-air and with rooms facing them, are crucial for daylight and natural ventilation. While courtyards... Read More about Pollutant cross-transmission in courtyard buildings: Wind tunnel experiments and computational fluid dynamics (CFD) evaluation.

The PI3Kδ inhibitor zandelisib on intermittent dosing in relapsed/refractory follicular lymphoma: Results from a global phase 2 study (2024)
Journal Article
Zelenetz, A. D., Jurczak, W., Ribrag, V., Linton, K., Collins, G. P., Jiménez, J. L., Bishton, M., Dholaria, B., Mengarelli, A., Phillips, T. J., Sungala, N., Musuraca, G., Sheehy, O., Van Den Neste, E., Odera, M., Miao, L., Gold, D. P., Ghalie, R. G., & Zinzani, P. L. (2024). The PI3Kδ inhibitor zandelisib on intermittent dosing in relapsed/refractory follicular lymphoma: Results from a global phase 2 study. HemaSphere, 8(8), Article e138. https://doi.org/10.1002/hem3.138

In this global phase 2 study in patients with relapsed/refractory follicular lymphoma (FL), zandelisib was administered on intermittent dosing to mitigate immune‐related adverse events and infections that have been reported with oral PI3Kδ inhibitors... Read More about The PI3Kδ inhibitor zandelisib on intermittent dosing in relapsed/refractory follicular lymphoma: Results from a global phase 2 study.

Visual Management in Collaboration (2024)
Book Chapter
Tezel, A., Demirkesen, S., Pedó, B., & Brandalise, . F. (2024). Visual Management in Collaboration. In S. Moradi, K. Kahkonen, L. Koskela, O. Jonny Klakegg, & K. Aaltonen (Eds.), Routledge Handbook of Collaboration in Construction. Taylor & Francis (Routledge). https://doi.org/10.1201/9781003379553

Collaboration is of utmost importance for dynamic and complex environments with multiple interfaces and interdependencies between system elements and humans. Collaboration enables effectively working systems where many people provide timely feedback,... Read More about Visual Management in Collaboration.

Topical anti-inflammatory treatments for eczema: network meta-analysis (2024)
Journal Article
Lax, S. J., Van Vogt, E., Candy, B., Steele, L., Reynolds, C., Stuart, B., Parker, R., Axon, E., Roberts, A., Doyle, M., Chu, D. K., Futamura, M., Santer, M., Williams, H. C., Cro, S., Drucker, A. M., & Boyle, R. J. (2024). Topical anti-inflammatory treatments for eczema: network meta-analysis. Cochrane Database of Systematic Reviews, 2024(8), Article CD015064. https://doi.org/10.1002/14651858.CD015064.pub2

BackgroundEczema (atopic dermatitis) is the most burdensome skin condition worldwide and cannot currently be prevented or cured. Topical anti-inflammatory treatments are used to control eczema symptoms, but there is uncertainty about the relative eff... Read More about Topical anti-inflammatory treatments for eczema: network meta-analysis.