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Fossilized records of past seas (2002)
Journal Article
Wade, C., & Darling, K. (2002). Fossilized records of past seas. Microbiology Today, 29, 183-184

The planktonic foraminifera are an important part of the zooplankton, and their calcific shells, preserved in the ocean sediments, form one of the most complete fossil records on earth. Chris Wade and Kate Darling explain how they can be used as indi... Read More about Fossilized records of past seas.

Purification of the proline-rich homeodomain protein (2002)
Journal Article
Butcher, A. J., Gaston, K., & Jayaraman, P. (2003). Purification of the proline-rich homeodomain protein. Journal of Chromatography B, 786(1-2), 3-6. https://doi.org/10.1016/S1570-0232%2802%2900740-7

The proline-rich homeodomain protein (PRH), also known as Hex, is a transcriptional repressor expressed in a variety of cell types. The PRH protein contains a proline-rich N-terminal domain that can repress transcription when attached to a heterologo... Read More about Purification of the proline-rich homeodomain protein.

The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: Allergen-induced Th2 bias determined at the dendritic cell level (2002)
Journal Article
Ghaemmaghami, A. M., Gough, L., Sewell, H. F., & Shakib, F. (2002). The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: Allergen-induced Th2 bias determined at the dendritic cell level. Clinical and Experimental Allergy, 32(10), 1468-1475. https://doi.org/10.1046/j.1365-2745.2002.01504.x

Background: The proteolytic activity of the house dust mite allergen Der p 1 has recently been shown to bias Th cell subset development in favour of Th2. Apart from its direct effect on T cells, it is conceivable that the proteolytic activity of Der... Read More about The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: Allergen-induced Th2 bias determined at the dendritic cell level.

Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial (2002)
Journal Article
Thomas, K., Muir, K., Doherty, M., Jones, A., O'Reilly, S., & Bassey, E. (2002). Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial

Objectives To determine whether a home based
exercise programme can improve outcomes in
patients with knee pain.
Design Pragmatic, factorial randomised controlled
trial of two years' duration.
Setting Two general practices in Nottingham.
Partic... Read More about Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial.

Comparing Postcolonial Literatures: Dislocations. (review) (2002)
Journal Article
Newman, J. (2002). Comparing Postcolonial Literatures: Dislocations. (review). Modern Language Review, 97(4),

Review of book edited by Ashok Berry and Patricia Murray.

Copyright 2002 MHRA, and included in the repository with permission.

The danger theory and its application to Artificial Immune Systems (2002)
Presentation / Conference Contribution
Aickelin, U., & Cayzer, S. (2002). The danger theory and its application to Artificial Immune Systems. In J. Timmis, & P. J. Bentley (Eds.), ICARIS 2002: 1st International Conference on Artificial Immune Systems (141-148)

Over the last decade, a new idea challenging the classical self-non-self viewpoint has become popular amongst immunologists. It is called the Danger Theory. In this conceptual paper, we look at this theory from the perspective of Artificial Immune Sy... Read More about The danger theory and its application to Artificial Immune Systems.

Hypothalamic Interactions Between Neuropeptide Y, Agouti-Related Protein, Cocaine- and Amphetamine-Regulated Transcript and Alpha-Melanocyte-Stimulating Hormone In Vitro in Male Rats (2002)
Journal Article
Dhillo, W. S., Small, C. J., Stanley, S. A., Jethwa, P. H., Seal, L. J., Murphy, K. G., …Bloom, S. R. (2002). Hypothalamic Interactions Between Neuropeptide Y, Agouti-Related Protein, Cocaine- and Amphetamine-Regulated Transcript and Alpha-Melanocyte-Stimulating Hormone In Vitro in Male Rats. Journal of Neuroendocrinology, 14(9), 725-730. https://doi.org/10.1046/j.1365-2826.2002.00832.x

A number of neuropeptides implicated in the hypothalamic regulation of appetite are synthesized in the arcuate nucleus (Arc). Neuropeptide Y (NPY) and agouti-related protein (Agrp) are orexigenic. The pro-opiomelanocortin (POMC) product alpha-melanoc... Read More about Hypothalamic Interactions Between Neuropeptide Y, Agouti-Related Protein, Cocaine- and Amphetamine-Regulated Transcript and Alpha-Melanocyte-Stimulating Hormone In Vitro in Male Rats.

Poverty, caring and older age (2002)
Journal Article
Argyle, E. (2002). Poverty, caring and older age

Due to the high incidence of disability amongst their contemporaries, older people are likely to be involved in informal caring relationships. Due to the limited nature of post-retirement incomes, such carers are also likely to be relatively poor. In... Read More about Poverty, caring and older age.

Inferring the phylogeny of disjunct populations of the azure-winged magpie Cyanopica cyanus from mitochondrial control region sequences (2002)
Journal Article
Koon, W. F., Wade, C. M., & Parkin, D. T. (2002). Inferring the phylogeny of disjunct populations of the azure-winged magpie Cyanopica cyanus from mitochondrial control region sequences. Proceedings of the Royal Society B: Biological Sciences, 269(1501), 1671-1679. https://doi.org/10.1098/rspb.2002.2057

The azure-winged magpie (AWM), Cyanopica cyanus, is found in Asia and Iberia. This remarkable disjunct distribution has been variously explained by either the sixteenth-century introduction of birds into Iberia from the Far East, or by the loss of in... Read More about Inferring the phylogeny of disjunct populations of the azure-winged magpie Cyanopica cyanus from mitochondrial control region sequences.

Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-Site: Structural variants of the C-Terminal Phe (2002)
Journal Article
Atkinson, G. E., Cowan, A., McInnes, C., Zheleva, D. I., Fischer, P. M., & Chan, W. C. (2002). Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-Site: Structural variants of the C-Terminal Phe. Bioorganic and Medicinal Chemistry Letters, 12(18), 2501-2505. https://doi.org/10.1016/S0960-894X%2802%2900508-5

A focused series of octapeptides based on the lead compound H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-NH2 1, in which the C-terminal phenylalanine residue was replaced by α and/or β-modified variants, was synthesized using solid-phase chemistry. Both the L-t... Read More about Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-Site: Structural variants of the C-Terminal Phe.

Vaccines against human enteric bacterial pathogens (2002)
Journal Article
Dougan, G., Huett, A., & Clare, S. (2002). Vaccines against human enteric bacterial pathogens. British Medical Bulletin, 62(1), 113-123. https://doi.org/10.1093/bmb/62.1.113

The development of vaccines against enteric bacterial pathogens presents a challenge because of the large number of pathogens capable of causing disease and the requirement to induce immunity that is effective in the gut. A new generation of enteric... Read More about Vaccines against human enteric bacterial pathogens.

Host/pathogen interactions at mucosal surfaces: Immune consequences (2002)
Journal Article
Clare, S., Huett, A., & Dougan, G. (2002). Host/pathogen interactions at mucosal surfaces: Immune consequences. Research in Microbiology, 153(7), 455-459. https://doi.org/10.1016/S0923-2508%2802%2901345-1

The mucosal immune system has evolved to protect the host against the establishment of infections at or through the mucosal surfaces of the body. Protective immunity must be activated to specific pathogenic agents or their products but inappropriate... Read More about Host/pathogen interactions at mucosal surfaces: Immune consequences.

Inferring the phylogeny of disjunct populations of the azure–winged magpie Cyanopica cyanus from mitochondrial control region sequences (2002)
Presentation / Conference Contribution
Koon Wah, F., Christopher M, W., & David, P. Inferring the phylogeny of disjunct populations of the azure–winged magpie Cyanopica cyanus from mitochondrial control region sequences

The azure–winged magpie (AWM), Cyanopica cyanus, is found in Asia and Iberia. This remarkable disjunct distribution has been variously explained by either the sixteenth–century introduction of birds into Iberia from the Far East, or by the loss of in... Read More about Inferring the phylogeny of disjunct populations of the azure–winged magpie Cyanopica cyanus from mitochondrial control region sequences.

The design and characterisation of an optical VLSI processor for real time centroid detection (2002)
Journal Article
Pui, B. H., Hayes-Gill, B., Clark, M., Somekh, M., See, C., Piéri, J. F., …Ng, A. (2002). The design and characterisation of an optical VLSI processor for real time centroid detection. Analog Integrated Circuits and Signal Processing, 32(1), 67-75. https://doi.org/10.1023/A%3A1016075825331

The integration of photo-detectors onto a standard CMOS integrated circuit is presented. This device provides the optical front end for a real time centroid detection system to be used as part of a larger system for implementing a Shack-Hartmann wave... Read More about The design and characterisation of an optical VLSI processor for real time centroid detection.

Missverständnisse, Rollenspiele, Double Binds: Kommunikation und Bewusstsein im Werk Birgit Vanderbekes (2002)
Journal Article
Uecker, M. (2002). Missverständnisse, Rollenspiele, Double Binds: Kommunikation und Bewusstsein im Werk Birgit Vanderbekes. German Life and Letters, 5(3), https://doi.org/10.1111/1468-0483.00232

Abweichend von der dominierenden Strategie der Literaturkritik, die das Werk Birgit Vanderbekes in erster Linie auf seine soziologische Repräsentativität für Entwicklungen der deutschen Gesellschaft seit den fünfziger Jahren untersucht hat, konzentri... Read More about Missverständnisse, Rollenspiele, Double Binds: Kommunikation und Bewusstsein im Werk Birgit Vanderbekes.

New treatments for atopic dermatitis (2002)
Journal Article
Williams, H. (2002). New treatments for atopic dermatitis. British medical journal, 324,

Atopic dermatitis now affects 15% to 20% of chil­dren in developed countries, and prevalence in cities in developing countries undergoingrapid demographic changes is quickly following suit. [1] Most cases of atopic dermatitis in a given communityare... Read More about New treatments for atopic dermatitis.

The Design of a Real Time VLSI Optical Centroid Processor (2002)
Presentation / Conference Contribution
Pui, B. H., Hayes-Gill, B., Clark, M., Somekh, M., See, C., Morgan, S., & Ng, A. (2002). The Design of a Real Time VLSI Optical Centroid Processor. In IEEE Sensors 2002 : first IEEE International Conference on Sensors. https://doi.org/10.1109/ICSENS.2002.1036977

A real time VLSI optical centroid processor has been developed as part of a larger Shack-Hartmann wavefront sensor system for applications in adaptive optics. The implementation of the optical centroid detection system was demonstrated successfully u... Read More about The Design of a Real Time VLSI Optical Centroid Processor.