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Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial (2024)
Journal Article
Hirschfield, G. M., Arndtz, K., Kirkham, A., Chen, Y.-Y., Fox, R., Rowe, A., Douglas-Pugh, J., Thorburn, D., Barnes, E., Aithal, G. P., Hull, D., Bhandal, K., Olsen, K., Woodward, P., Lax, S., Newsome, P., Smith, D. J., Kallio, A., Adams, D. H., Homer, V., & Weston, C. J. (2024). Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial. Hepatology Communications, 8(5), Article e0426. https://doi.org/10.1097/hc9.0000000000000426

Background:
Primary sclerosing cholangitis is a progressive inflammatory liver disease characterized by biliary and liver fibrosis. Vascular adhesion protein-1 (VAP-1) is important in the inflammatory process driving liver fibrosis. We evaluated th... Read More about Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial.

‘Take Back Control’: The implications of Brexit uncertainty on investor perception of ESG reputational events (2024)
Journal Article
Akyildirim, E., Conlon, T., Corbet, S., & Oxley, L. (2024). ‘Take Back Control’: The implications of Brexit uncertainty on investor perception of ESG reputational events. European Financial Management, https://doi.org/10.1111/eufm.12490

This study examines the impact of Brexit on investor reactions to Environmental, Social, and Governance (ESG) events in UK companies. Post-Brexit, investors show reduced sensitivity to ESG incidents, suggesting relaxed corporate accountability for ES... Read More about ‘Take Back Control’: The implications of Brexit uncertainty on investor perception of ESG reputational events.

Is breathing frequency a potential means for monitoring exercise intensity in people with atrial fibrillation and coronary heart disease when heart rate is mitigated? (2024)
Journal Article
Buckley, J. P., Terada, T., Lion, A., & Reed, J. L. (2024). Is breathing frequency a potential means for monitoring exercise intensity in people with atrial fibrillation and coronary heart disease when heart rate is mitigated?. European Journal of Applied Physiology, 124, 2881–2891. https://doi.org/10.1007/s00421-024-05487-2

Purpose: Moderate-intensity aerobic exercise is safe and beneficial in atrial fibrillation (AF) and coronary heart disease (CHD). Irregular or rapid heart rates (HR) in AF and other heart conditions create a challenge to using HR to monitor exercise... Read More about Is breathing frequency a potential means for monitoring exercise intensity in people with atrial fibrillation and coronary heart disease when heart rate is mitigated?.

Mobilizing Metaphors in Criminological Analysis: A Case Study of Emotions in the Penal Voluntary Sector (2024)
Journal Article
Quinn, K., Buck, G., & Tomczak, P. (2024). Mobilizing Metaphors in Criminological Analysis: A Case Study of Emotions in the Penal Voluntary Sector. British Journal of Criminology, 64(6), 1239-1258. https://doi.org/10.1093/bjc/azae027

Metaphors pervade media and political constructions of crime and justice, provoking responses and shaping actions. Scholarship in adjacent disciplines illustrates that emotion-metaphors offer unique insight into emotional and interpretive processes,... Read More about Mobilizing Metaphors in Criminological Analysis: A Case Study of Emotions in the Penal Voluntary Sector.

Importance of FDA-Integrated Continuous Glucose Monitors to Ensure Accuracy of Continuous Glucose Monitoring (2024)
Journal Article
Klonoff, D. C., Gabbay, M., Moon, S. J., & Wilmot, E. G. (2024). Importance of FDA-Integrated Continuous Glucose Monitors to Ensure Accuracy of Continuous Glucose Monitoring. Journal of Diabetes Science and Technology, https://doi.org/10.1177/19322968241250357

Continuous glucose monitoring (CGM) has been shown to improve glycemic control and self-monitoring, as well as to reduce the risk of hypoglycemia. Integrated CGM (iCGM) FDA-cleared systems with published performance data are established nonadjunctive... Read More about Importance of FDA-Integrated Continuous Glucose Monitors to Ensure Accuracy of Continuous Glucose Monitoring.

Multiple drug-delivery strategies to enhance the pharmacological and toxicological properties of Mefenamic acid (2024)
Journal Article
Cristiano, C., Cavanagh, R. J., Cuzzucoli Crucitti, V., Moloney, C., Axioti, E., Dixon, E., …Rimoli, M. G. (2024). Multiple drug-delivery strategies to enhance the pharmacological and toxicological properties of Mefenamic acid. Biomedicine and Pharmacotherapy, 175, Article 116647. https://doi.org/10.1016/j.biopha.2024.116647

Objective: To improve the biological and toxicological properties of Mefenamic acid (MA), the galactosylated prodrug of MA named MefeGAL was included in polymeric solid dispersions (PSs) composed of poly(glycerol adipate) (PGA) and Pluronic® F68 (Mef... Read More about Multiple drug-delivery strategies to enhance the pharmacological and toxicological properties of Mefenamic acid.

Microwave thermal pre-treatment and calcination of biomineralised sorbents for calcium looping (2024)
Journal Article
Erans, M., Durán-Jimenez, G., Rodríguez, J. M., Stevens, L., & Dodds, C. (2024). Microwave thermal pre-treatment and calcination of biomineralised sorbents for calcium looping. Journal of Co2 Utilization, 83, Article 102794. https://doi.org/10.1016/j.jcou.2024.102794

Waste eggshells have been investigated as biomineralised CO2 sorbents for the calcium looping cycle due to their high Ca content, low cost, availability, and high CO2 uptake. This work investigates a novel heat-pre-treatment using eggshells as raw ma... Read More about Microwave thermal pre-treatment and calcination of biomineralised sorbents for calcium looping.

Predicting the risk of pancreatic cancer in adults with new-onset diabetes: development and internal–external validation of a clinical risk prediction model (2024)
Journal Article
Clift, A. K., Tan, P. S., Patone, M., Liao, W., Coupland, C., Bashford-Rogers, R., Sivakumar, S., & Hippisley-Cox, J. (2024). Predicting the risk of pancreatic cancer in adults with new-onset diabetes: development and internal–external validation of a clinical risk prediction model. British Journal of Cancer, 130, 1969-1978. https://doi.org/10.1038/s41416-024-02693-9

Background: The National Institute for Health and Care Excellence (NICE) recommends that people aged 60+ years with newly diagnosed diabetes and weight loss undergo abdominal imaging to assess for pancreatic cancer. More nuanced stratification could... Read More about Predicting the risk of pancreatic cancer in adults with new-onset diabetes: development and internal–external validation of a clinical risk prediction model.

A method for the ethical analysis of brain-inspired AI (2024)
Journal Article
Farisco, M., Baldassarre, G., Cartoni, E., Leach, A., Petrovici, M. A., Rosemann, A., Salles, A., Stahl, B., & van Albada, S. J. (2024). A method for the ethical analysis of brain-inspired AI. Artificial Intelligence Review, 57(6), Article 133. https://doi.org/10.1007/s10462-024-10769-4

Despite its successes, to date Artificial Intelligence (AI) is still characterized by a number of shortcomings with regards to different application domains and goals. These limitations are arguably both conceptual (e.g., related to the underlying th... Read More about A method for the ethical analysis of brain-inspired AI.

Beyond the Walls: Patterns of Child Labour, Forced Labour, and Exploitation in a New Domestic Workers Dataset (2024)
Journal Article
Trodd, Z., Waite, C., Goulding, J., & Boyd, D. S. (2024). Beyond the Walls: Patterns of Child Labour, Forced Labour, and Exploitation in a New Domestic Workers Dataset. Societies, 14(5), Article 62. https://doi.org/10.3390/soc14050062

The new Domestic Workers Dataset is the largest single set of surveys (n = 11,759) of domestic workers to date. Our analysis of this dataset reveals features about the lives and work of this “hard-to-find” population in India—a country estimated to h... Read More about Beyond the Walls: Patterns of Child Labour, Forced Labour, and Exploitation in a New Domestic Workers Dataset.

The separate effect of halo mass and stellar mass on the evolution of massive disc galaxies (2024)
Journal Article
Zhou, S., Aragón-Salamanca, A., & Merrifield, M. (2024). The separate effect of halo mass and stellar mass on the evolution of massive disc galaxies. Monthly Notices of the Royal Astronomical Society, 530(4), 4082-4093. https://doi.org/10.1093/mnras/stae1127

We analyse a sample of massive disc galaxies selected from the fourth-generation Sloan Digital Sky Survey/Mapping Nearby Galaxies at Apache Point Observatory survey to investigate how the evolution of these galaxies depends on their stellar and halo... Read More about The separate effect of halo mass and stellar mass on the evolution of massive disc galaxies.

Post-discharge surgical site infection surveillance using patient smartphones: a single-centre experience in cardiac surgery (2024)
Journal Article
Rochon, M., Tanner, J., Cariaga, K., Ingusan, S. D., Jawarchan, A., Morais, C., Odattil, B., & Dizon, R. (2024). Post-discharge surgical site infection surveillance using patient smartphones: a single-centre experience in cardiac surgery. British Journal of Cardiac Nursing, 19(5), 1-11. https://doi.org/10.12968/bjca.2023.0099

Background/Aims Surgical site infections following cardiac surgery pose significant risks and financial burdens to both patients and healthcare systems. This study aimed to explore the implementation and outcomes of a novel surgical wound monitoring... Read More about Post-discharge surgical site infection surveillance using patient smartphones: a single-centre experience in cardiac surgery.

Metformin for endometrial hyperplasia (2024)
Journal Article
Shiwani, H., Clement, N. S., Daniels, J. P., & Atiomo, W. (2024). Metformin for endometrial hyperplasia. Cochrane Database of Systematic Reviews, 2024(5), Article CD012214. https://doi.org/10.1002/14651858.cd012214.pub3

Background
Endometrial cancer is one of the most common gynaecological cancers in the world. Rates of endometrial cancer are rising, in part because of rising obesity rates. Endometrial hyperplasia is a precancerous condition in women that can lead... Read More about Metformin for endometrial hyperplasia.

Health professional attitudes and perceptions of prehabilitation and nutrition before haematopoietic cell transplantation (2024)
Journal Article
Miller, L. J., Halliday, V., Snowden, J. A., Aithal, G. P., Lee, J., & Greenfield, D. M. (2024). Health professional attitudes and perceptions of prehabilitation and nutrition before haematopoietic cell transplantation. Journal of Human Nutrition and Dietetics, 37(4), 1007-1021. https://doi.org/10.1111/jhn.13315

Background
Nutritional prehabilitation may improve haematopoietic cell transplantation (HCT) outcomes, although little evidence exists. The present study aimed to understand healthcare professional (HCP) perceptions of prehabilitation and nutritiona... Read More about Health professional attitudes and perceptions of prehabilitation and nutrition before haematopoietic cell transplantation.

The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact (2024)
Journal Article
Kalaria, R., Maestre, G., Mahinrad, S., Acosta, D. M., Akinyemi, R. O., Alladi, S., Allegri, R. F., Arshad, F., Babalola, D. O., Baiyewu, O., Bak, T. H., Bellaj, T., Brodie‐Mends, D. K., Carrillo, M. C., Celestin, K., Damasceno, A., de Silva, R. K., de Silva, R., Djibuti, M., Dreyer, A. J., …Ismail, O. (2024). The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(6), 4290-4314. https://doi.org/10.1002/alz.13836

Two of every three persons living with dementia reside in low‐ and middle‐income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs oc... Read More about The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact.

Prevalence and distributions of severely elevated low-density lipoprotein cholesterol (LDL-c) according to age, gender and clinic location among patients in the Malaysian primary care (2024)
Journal Article
Kanchau, J. D., Akyea, R. K., Baharudin, N., Mohamed-Yassin, M., Kamal, A., Chua, Y., …Ramli, A. S. (2024). Prevalence and distributions of severely elevated low-density lipoprotein cholesterol (LDL-c) according to age, gender and clinic location among patients in the Malaysian primary care. Clinical Epidemiology and Global Health, 27, Article 101619. https://doi.org/10.1016/j.cegh.2024.101619

Background
Adults with severely elevated low-density lipoprotein cholesterol (LDL-c) may have familial hypercholesterolaemia (FH) and are at high risk of atherosclerotic cardiovascular disease (ASCVD). The prevalence of elevated LDL-c in primary car... Read More about Prevalence and distributions of severely elevated low-density lipoprotein cholesterol (LDL-c) according to age, gender and clinic location among patients in the Malaysian primary care.

End of life decision making when home mechanical ventilation is used to sustain breathing in Motor Neurone Disease: patient and family perspectives (2024)
Journal Article
Wilson, E., Palmer, J., Armstrong, A., Messer, B., Presswood, E., & Faull, C. (2024). End of life decision making when home mechanical ventilation is used to sustain breathing in Motor Neurone Disease: patient and family perspectives. BMC Palliative Care, 23(1), Article 115. https://doi.org/10.1186/s12904-024-01443-1

Background
Motor Neurone Disease (MND) leads to muscle weakening, affecting movement, speech, and breathing. Home mechanical ventilation, particularly non-invasive ventilation (NIV), is used to alleviate symptoms and support breathing in people livi... Read More about End of life decision making when home mechanical ventilation is used to sustain breathing in Motor Neurone Disease: patient and family perspectives.

Iterative solution methods for high-order/hp–DGFEM approximation of the linear Boltzmann transport equation (2024)
Journal Article
Houston, P., Hubbard, M. E., & Radley, T. J. (2024). Iterative solution methods for high-order/hp–DGFEM approximation of the linear Boltzmann transport equation. Computers and Mathematics with Applications, 166, 37-49. https://doi.org/10.1016/j.camwa.2024.04.011

In this article we consider the iterative solution of the linear system of equations arising from the discretisation of the poly-energetic linear Boltzmann transport equation using a high-order/hp–version discontinuous Galerkin finite element approxi... Read More about Iterative solution methods for high-order/hp–DGFEM approximation of the linear Boltzmann transport equation.