All Outputs (2545)

Effects of Microenvironment and Dosing on Efficiency of Enhanced Cell Penetrating Peptide Nonviral Gene Delivery (2024)
Journal Article
Dixon, J. E., Wellington, V., Elnima, A., & Eltaher, H. M. (2024). Effects of Microenvironment and Dosing on Efficiency of Enhanced Cell Penetrating Peptide Nonviral Gene Delivery. ACS Omega, 9(4), 5014-5023. https://doi.org/10.1021/acsomega.3c09306

Transfection, defined as functional delivery of cell-internalized nucleic acids, is dependent on many factors linked to formulation, vector, cell type, and microenvironmental culture conditions. We previously developed a technology termed glycosamino... Read More about Effects of Microenvironment and Dosing on Efficiency of Enhanced Cell Penetrating Peptide Nonviral Gene Delivery.

When Vegas comes to Wall Street: Associations between stock price volatility and trading frequency among gamblers (2024)
Journal Article
Weiss-Cohen, L., Newall, P., Bart, Y., Zloteanu, M., Peacey, M., Ayton, P., & Clacher, I. (2024). When Vegas comes to Wall Street: Associations between stock price volatility and trading frequency among gamblers. International Journal of Mental Health and Addiction, https://doi.org/10.1007/s11469-023-01229-1

Both gambling and trading involve risk-taking in exchange for potential financial gains. In particular, speculative high-risk high-frequency trading closely resembles disordered gambling behaviour by attracting the same individuals who tend to be ove... Read More about When Vegas comes to Wall Street: Associations between stock price volatility and trading frequency among gamblers.

De Systematibus Civitatum: Pufendorf on Confederations and Composite Kingdoms (2024)
Book Chapter
Holland, B. (2024). De Systematibus Civitatum: Pufendorf on Confederations and Composite Kingdoms. In P. Schröder (Ed.), Concepts and Contexts of Pufendorf's International Legal and Political Thought (41-58). Oxford University Press (OUP)

This chapter investigates Pufendorf’s concept of systema civitatum or ‘system of states’. The chapter illuminates the concept by excavating it in several contexts. First, it examines the evolution of the term in Pufendorf’s own writings, from his ear... Read More about De Systematibus Civitatum: Pufendorf on Confederations and Composite Kingdoms.

Template‐Directed Synthesis of Strained meso‐meso‐Linked Porphyrin Nanorings (2024)
Journal Article
Van Raden, J. M., Deng, J., Gotfredsen, H., Hergenhahn, J., Clarke, M., Edmondson, M., …Anderson, H. L. (2024). Template‐Directed Synthesis of Strained meso‐meso‐Linked Porphyrin Nanorings. Angewandte Chemie International Edition, Article e202400103. https://doi.org/10.1002/anie.202400103

Strained macrocycles display interesting properties, such as conformational rigidity, often resulting in enhance π‐conjugation or enhanced affinity for non‐covalent guest binding, yet they can be difficult to synthesize. Here we use computational mod... Read More about Template‐Directed Synthesis of Strained meso‐meso‐Linked Porphyrin Nanorings.

Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study (2024)
Journal Article
Azam, A. S., Tsang, Y., Thirlwall, J., Kimani, P. K., Sah, S., Gopalakrishnan, K., …Snead, D. R. J. (2024). Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study. Histopathology, 84(5), 847-862. https://doi.org/10.1111/his.15129

Aims: To conduct a definitive multicentre comparison of digital pathology (DP) with light microscopy (LM) for reporting histopathology slides including breast and bowel cancer screening samples.
Methods: A total of 2024 cases (608 breast, 607 GI, 6... Read More about Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study.

The Hepatokine Leukocyte Cell-Derived Chemotaxin-2 Is Elevated in People with Impaired Glycaemic Regulation and Augmented by Acute Exercise (2024)
Journal Article
Engin, B., Willis, S. A., Malaikah, S., Sargeant, J. A., Stensel, D. J., Jelleyman, C., …King, J. A. (2024). The Hepatokine Leukocyte Cell-Derived Chemotaxin-2 Is Elevated in People with Impaired Glycaemic Regulation and Augmented by Acute Exercise. Livers, 4(1), 51-62. https://doi.org/10.3390/livers4010005

The hepatokine leukocyte cell-derived chemotaxin-2 (LECT2) promotes insulin resistance and hepatic fibrogenesis. In rodents, acute exercise suppresses circulating LECT2; however, human data are lacking. This study compared circulating LECT2 across po... Read More about The Hepatokine Leukocyte Cell-Derived Chemotaxin-2 Is Elevated in People with Impaired Glycaemic Regulation and Augmented by Acute Exercise.

Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial (2024)
Journal Article
Pesola, F., Smith, K. M., Phillips‐Waller, A., Przulj, D., Griffiths, C., Walton, R., …Hajek, P. (2024). Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial. Addiction, 119(5), 875-884. https://doi.org/10.1111/add.16422

Aims: The aim of this study was to examine the safety of e-cigarettes (EC) and nicotine patches (NRT) when used to help pregnant smokers quit. Design: A recent trial of EC versus NRT reported safety outcomes in the randomized arms. We conducted a fur... Read More about Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial.

Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK (2024)
Journal Article
Jewitt, S., McClaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK. Veterinary Record, 195(5), Article e3713. https://doi.org/10.1002/vetr.3713

Background
The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented.

Methods
An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK.

Multi-agent cooperative swarm learning for dynamic layout optimisation of reconfigurable robotic assembly cells based on digital twin (2024)
Journal Article
Wang, L., Wang, Z., Gumma, K., Turner, A., & Ratchev, S. (in press). Multi-agent cooperative swarm learning for dynamic layout optimisation of reconfigurable robotic assembly cells based on digital twin. Journal of Intelligent Manufacturing, https://doi.org/10.1007/s10845-023-02229-7

To meet the requirement of product variety and short production cycle, reconfigurable manufacturing system is considered as an effective solution in addressing current challenges, such as increasing customisation, high flexibility and dynamic market... Read More about Multi-agent cooperative swarm learning for dynamic layout optimisation of reconfigurable robotic assembly cells based on digital twin.

Vacua in locally de Sitter cosmologies, and how to distinguish them (2024)
Journal Article
Toussaint, V., & Louko, J. (2024). Vacua in locally de Sitter cosmologies, and how to distinguish them. Physical Review D, 109(2), Article 025007. https://doi.org/10.1103/physrevd.109.025007

(1 + 1)-dimensional locally de Sitter–Friedmann-Robertson-Walker cosmologies with compact spatial sections allow cosh, sinh, and exponential evolution laws, each with a freely specifiable spatial circumference parameter, and the value of this paramet... Read More about Vacua in locally de Sitter cosmologies, and how to distinguish them.

Assessing spontaneous sensory neuron activity usingin vivocalcium imaging (2024)
Preprint / Working Paper
Ingram, S. L., Chisholm, K. I., Wang, F., De Koninck, Y., Denk, F., & Goodwin, G. L. Assessing spontaneous sensory neuron activity usingin vivocalcium imaging

Heightened spontaneous activity in sensory neurons is often reported in individuals living with chronic pain. It is possible to study this activity in rodents using electrophysiology, but these experiments require great skill and can be prone to bias... Read More about Assessing spontaneous sensory neuron activity usingin vivocalcium imaging.

Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomised controlled trial (2024)
Journal Article
Pesola, F., Smith, K. M., Phillips-Waller, A., Przulj, D., Griffiths, C., Walton, R., …Hajek, P. (2024). Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomised controlled trial. Addiction, 119(5), 875-884. https://doi.org/10.1111/add.16422

Aims

To examine safety of e-cigarettes (EC) and nicotine patches (NRT) when used to help pregnant smokers quit.

Design

A recent trial of EC versus NRT reported safety outcomes in the randomised arms. We conducted a further analysis based... Read More about Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomised controlled trial.

The best of times, the worst of times: Continuities in school leaders' work in uncertain times (2024)
Journal Article
Thomson, P., & Greany, T. (in press). The best of times, the worst of times: Continuities in school leaders' work in uncertain times. Educational Management Administration and Leadership, https://doi.org/10.1177/17411432231218544

The COVID 19 pandemic created new challenges for school leaders. They worked very long hours in difficult circumstances. Improvising and responding quickly to poorly timed central guidelines had an adverse effect on their health and wellbeing. Our mi... Read More about The best of times, the worst of times: Continuities in school leaders' work in uncertain times.

Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom (2024)
Journal Article
Jewitt, S., Mcclaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom. Veterinary Record, 195(5), Article e3713. https://doi.org/10.1002/vetr.3713

Background
The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented.

Methods
An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom.

The impact of emotional valence on generalization gradients (2024)
Journal Article
Alcalá, J. A., Martínez-Tomás, C., Urcelay, G. P., & Hinojosa, J. A. (2024). The impact of emotional valence on generalization gradients. Psychonomic Bulletin and Review, 31, 1670-1679. https://doi.org/10.3758/s13423-023-02450-8

Generalization enables individuals to respond to novel stimuli based on previous experiences. The degree to which organisms respond is determined by their physical resemblance to the original conditioned stimulus (CS+), with a stronger response elici... Read More about The impact of emotional valence on generalization gradients.

Speed‐current single‐loop control of PMSM based on model‐assisted cascaded extended state observer and sliding mode control (2024)
Journal Article
Wang, M., Liu, Y., Wang, Q., Liao, Y., & Wheeler, P. (2024). Speed‐current single‐loop control of PMSM based on model‐assisted cascaded extended state observer and sliding mode control. International Journal of Circuit Theory and Applications, 52(7), 3558-3583. https://doi.org/10.1002/cta.3929

This paper proposes a novel speed‐current single‐loop speed regulation controller for permanent magnet synchronous motor (PMSM) based on model‐assisted cascaded extended state observer (ESO) and sliding mode control (SMC), aimed at simplifying the co... Read More about Speed‐current single‐loop control of PMSM based on model‐assisted cascaded extended state observer and sliding mode control.

Silicon Carbide n-IGBTs: Structure Optimization for Ruggedness Enhancement (2024)
Journal Article
Almpanis, I., Antoniou, M., Evans, P., Empringham, L., Gammon, P., Undrea, F., …Lophitis, N. (2024). Silicon Carbide n-IGBTs: Structure Optimization for Ruggedness Enhancement. IEEE Transactions on Industry Applications, 60(3), 4251-4263. https://doi.org/10.1109/tia.2024.3354870

In recent years, silicon carbide (SiC) based devices are increasingly replacing their silicon counterparts in power conversion applications due to their performance superiority. SiC insulated-gate bipolar transistors are particularly interesting as t... Read More about Silicon Carbide n-IGBTs: Structure Optimization for Ruggedness Enhancement.

Author Response: Glutaredoxin regulation of primary root growth is associated with early drought stress tolerance in pearl millet (2024)
Preprint / Working Paper
de la Fuente, C., Grondin, A., Sine, B., Debieu, M., Belin, C., Hajjarpoor, A., …Laplaze, L. Author Response: Glutaredoxin regulation of primary root growth is associated with early drought stress tolerance in pearl millet

Seedling root traits impact plant establishment under challenging environments. Pearl millet is one of the most heat and drought tolerant cereal crops that provides a vital food source across the sub-Saharan Sahel region. Pearl millet’s early root sy... Read More about Author Response: Glutaredoxin regulation of primary root growth is associated with early drought stress tolerance in pearl millet.

Social understanding of inattention: An examination of the representation of inattentive behaviour in clinical, educational and family textual contexts (2024)
Journal Article
Vilar-Lluch, S. (2024). Social understanding of inattention: An examination of the representation of inattentive behaviour in clinical, educational and family textual contexts. Communication and Medicine, 19(1), 26-41. https://doi.org/10.1558/cam.22379

Inattention, one of the defining traits of Attention Deficit Hyperactivity-Impulsivity Disorder (ADHD), is occasionally perceived as less worrying than hyperactivity and impulsivity. However, those individuals who manifest it are often targets of neg... Read More about Social understanding of inattention: An examination of the representation of inattentive behaviour in clinical, educational and family textual contexts.

Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial (2024)
Journal Article
Morriss, R., Briley, P. M., Webster, L., Abdelghani, M., Barber, S., Bates, P., …Auer, D. P. (2024). Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial. Nature Medicine, 30(2), 403–413. https://doi.org/10.1038/s41591-023-02764-z

Disruption in reciprocal connectivity between the right anterior insula and the left dorsolateral prefrontal cortex is associated with depression and may be a target for neuromodulation. In a five-center, parallel, double-blind, randomized controlled... Read More about Connectivity-guided intermittent theta burst versus repetitive transcranial magnetic stimulation for treatment-resistant depression: a randomized controlled trial.