All Outputs (3501)

Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study (2022)
Journal Article
Swain, S., Coupland, C., Strauss, V., Mallen, C., Kuo, C. F., Sarmanova, A., …Zhang, W. (2022). Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study. Osteoarthritis and Cartilage, 30(5), 702-713. https://doi.org/10.1016/j.joca.2021.12.013

Objective: To examine the clusters of chronic conditions present in people with osteoarthritis and the associated risk factors and health outcomes. Methods: Clinical Practice Research Datalink (CPRD) GOLD was used to identify people diagnosed with in... Read More about Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study.

Imitation learning for coordinated human–robot collaboration based on hidden state-space models (2022)
Journal Article
Wang, L., Wang, G., Jia, S., Turner, A., & Ratchev, S. (2022). Imitation learning for coordinated human–robot collaboration based on hidden state-space models. Robotics and Computer-Integrated Manufacturing, 76, Article 102310. https://doi.org/10.1016/j.rcim.2021.102310

This paper proposes a novel coordinated human–robot collaboration framework based on the hidden state-space model, which probabilistically clones the human behaviour and presents dynamic features in a nonparametric form. Derived from the filter predi... Read More about Imitation learning for coordinated human–robot collaboration based on hidden state-space models.

Systematic review of pharmacological interventions for people with Lewy body dementia (2022)
Journal Article
Watts, K. E., Storr, N. J., Barr, P. G., & Rajkumar, A. P. (2022). Systematic review of pharmacological interventions for people with Lewy body dementia. Aging and Mental Health, 27(2), 203-216. https://doi.org/10.1080/13607863.2022.2032601

Objective: Lewy body dementia (LBD) is the second most common neurodegenerative dementia, and it causes earlier mortality and more morbidity than Alzheimer’s disease. Reviewing current evidence on its pharmacological management is essential for devel... Read More about Systematic review of pharmacological interventions for people with Lewy body dementia.

Torque Limiters for Aerospace Actuator Application (2022)
Journal Article
Shahjahan Ahmad, S., Tom, L., La Rocca, A., La Rocca, S., Vakil, G., Gerada, C., & Benarous, M. (2022). Torque Limiters for Aerospace Actuator Application. Energies, 15(4), Article 1467. https://doi.org/10.3390/en15041467

Safety and reliability of electrical actuators are essential for success of all electric and more electric aircrafts (MEA). Torque limiters improve the reliability of electromechanical actuators (EMA) by restricting the amount of force experienced by... Read More about Torque Limiters for Aerospace Actuator Application.

Human, Organisational and Societal Factors in Robotic Rail Infrastructure Maintenance (2022)
Journal Article
Golightly, D., Chan-Pensley, J., Dadashi, N., Jundi, S., Ryan, B., & Hall, A. (2022). Human, Organisational and Societal Factors in Robotic Rail Infrastructure Maintenance. Sustainability, 14(4), 1-28. https://doi.org/10.3390/su14042123

Robotics are set to play a significant role in the maintenance of rail infrastructure. However, the introduction of robotics in this environment requires new ways of working for individuals, teams and organisations and needs to reflect societal attit... Read More about Human, Organisational and Societal Factors in Robotic Rail Infrastructure Maintenance.

Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers” (2022)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., …Wildman, R. D. (2022). Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers”. ACS Applied Materials and Interfaces, 14(6), 8654. https://doi.org/10.1021/acsami.2c00035

The chemical structure of the drug trandolapril has been corrected in Figure 4c. The conclusions of the work have not been affected by this correction. (Figure present).

A Simple Whole-Plasmid PCR Method to Construct High-Diversity Synthetic Phage Display Libraries (2022)
Journal Article
Tsoumpeli, M. T., Gray, A., Parsons, A. L., Spiliotopoulos, A., Owen, J. P., Bishop, K., …Gough, K. C. (2022). A Simple Whole-Plasmid PCR Method to Construct High-Diversity Synthetic Phage Display Libraries. Molecular Biotechnology, 64, 791-803. https://doi.org/10.1007/s12033-021-00442-4

Phage display technology utilises peptide and antibody libraries with very high diversities to select ligands with specific binding properties. The production of such libraries can be labour intensive and technically challenging and whilst there are... Read More about A Simple Whole-Plasmid PCR Method to Construct High-Diversity Synthetic Phage Display Libraries.

The effect of environmental temperature on average daily gain in preweaned calves: A randomized controlled trial and Bayesian analysis (2022)
Journal Article
Hyde, R. M., Green, M. J., Hudson, C., & Down, P. M. (2022). The effect of environmental temperature on average daily gain in preweaned calves: A randomized controlled trial and Bayesian analysis. Journal of Dairy Science, 105(4), 3430-3439. https://doi.org/10.3168/jds.2021-21199

Neonatal calves are relatively susceptible to heat loss, and previous research suggests that reduced environmental temperatures are associated with reduced average daily gain (ADG) during the preweaning phase. Current methods of mitigating negative e... Read More about The effect of environmental temperature on average daily gain in preweaned calves: A randomized controlled trial and Bayesian analysis.

Characterisation of fatigue damage in asphalt mixtures using X-ray computed tomography (2022)
Journal Article
Chen, A., Airey, G., Thom, N., & Li, Y. (2023). Characterisation of fatigue damage in asphalt mixtures using X-ray computed tomography. Road Materials and Pavement Design, 24(3), 653-671. https://doi.org/10.1080/14680629.2022.2029756

The high-resolution X-ray CT was applied to investigate the fatigue damage evolution of asphalt mixtures. The detailed Xray CT images in the centre of the samples were used to characterise the fatigue cracking and air voids increase at different vert... Read More about Characterisation of fatigue damage in asphalt mixtures using X-ray computed tomography.

Spatial Growth Rate of Emerging SARS-CoV-2 Lineages in England, September 2020–December 2021 (2022)
Preprint / Working Paper
The COVID-19 Genomics UK (COG-UK) Consortium, Smallman-Raynor, M., & Cliff, A. D. Spatial Growth Rate of Emerging SARS-CoV-2 Lineages in England, September 2020–December 2021

This paper uses a robust method of spatial epidemiological analysis to assess the spatial growth rate of multiple lineages of SARS-CoV-2 in the local authority areas of England, September 2020-December 2021. Using the genomic surveillance records of... Read More about Spatial Growth Rate of Emerging SARS-CoV-2 Lineages in England, September 2020–December 2021.

Quadratic curvature corrections to stringy effective actions and the absence of de Sitter vacua (2022)
Journal Article
Cunillera, F., Emond, W. T., Lehébel, A., & Padilla, A. (2022). Quadratic curvature corrections to stringy effective actions and the absence of de Sitter vacua. Journal of High Energy Physics, 2022(2), Article 12. https://doi.org/10.1007/jhep02%282022%29012

We investigate the combined effect of fluxes and higher-order curvature corrections, in the form of the Gauss-Bonnet term, on the existence of de Sitter vacua in a heterotic string inspired framework, compactified on spheres and tori. We first gain s... Read More about Quadratic curvature corrections to stringy effective actions and the absence of de Sitter vacua.

Current status and future development of hybrid PV/T system with PCM module: 4E (energy, exergy, economic and environmental) assessments (2022)
Journal Article
Cui, Y., Zhu, J., Zhang, F., Shao, Y., & Xue, Y. (2022). Current status and future development of hybrid PV/T system with PCM module: 4E (energy, exergy, economic and environmental) assessments. Renewable and Sustainable Energy Reviews, 158, Article 112147. https://doi.org/10.1016/j.rser.2022.112147

Solar photovoltaic thermal (PV/T) with phase change material (PCM) technology is one of the incentive research areas in renewable energy application aspect, which attracts increasingly attention in the globalized market to tackle climate change. The... Read More about Current status and future development of hybrid PV/T system with PCM module: 4E (energy, exergy, economic and environmental) assessments.

A Novel Bacteriophage with Broad Host Range against Clostridioides difficile Ribotype 078 Supports SlpA as the Likely Phage Receptor (2022)
Journal Article
Whittle, M. J., Bilverstone, T. W., Van Esveld, R. J., Lücke, A. C., Lister, M. M., Kuehne, S. A., & Minton, N. P. (2022). A Novel Bacteriophage with Broad Host Range against Clostridioides difficile Ribotype 078 Supports SlpA as the Likely Phage Receptor. Microbiology Spectrum, 10(1), Article e02295-21. https://doi.org/10.1128/spectrum.02295-21

Bacteriophages represent a promising option for the treatment of Clostridioides difficile (formerly Clostridium difficile) infection (CDI), which at present relies on conventional antibiotic therapy. The specificity of bacteriophages should prevent d... Read More about A Novel Bacteriophage with Broad Host Range against Clostridioides difficile Ribotype 078 Supports SlpA as the Likely Phage Receptor.

Fluid dynamics and cell-bound Psl polysaccharide allows microplastic capture, aggregation and subsequent sedimentation by Pseudomonas aeruginosa in water (2022)
Journal Article
Romero, M., Carabelli, A., Swift, M., & Smith, M. (2022). Fluid dynamics and cell-bound Psl polysaccharide allows microplastic capture, aggregation and subsequent sedimentation by Pseudomonas aeruginosa in water. Environmental Microbiology, 24(3), 1560-1572. https://doi.org/10.1111/1462-2920.15916

Decades after incorporating plastics into consumer markets, research shows that these polymers have spread worldwide. Fragmentation of large debris leads to smaller particles, collectively called microplastics (MPs), which have become ubiquitous in a... Read More about Fluid dynamics and cell-bound Psl polysaccharide allows microplastic capture, aggregation and subsequent sedimentation by Pseudomonas aeruginosa in water.

The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records (2022)
Journal Article
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Butler, D., Hollis, C., …Coupland, C. (2022). The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records. BMC Medicine, 20(1), Article 43. https://doi.org/10.1186/s12916-022-02247-x

Background
Studies have reported an increased risk of mortality among people prescribed mirtazapine compared to other antidepressants. The study aimed to compare all-cause and cause-specific mortality between adults prescribed mirtazapine or other s... Read More about The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records.

Mitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway (2022)
Journal Article
Barreto, P., Dambire, C., Sharma, G., Vicente, J., Osborne, R., De Carvalho, J. E., …Arruda, P. (2022). Mitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway. Current Biology, 32(6), 1403-1411.e4. https://doi.org/10.1016/j.cub.2022.01.037

Mitochondrial retrograde signaling is an important component of intracellular stress signaling in eukaryotes. UNCOUPLING PROTEIN (UCP)1 is an abundant plant inner-mitochondrial membrane protein with multiple functions including uncoupled respiration... Read More about Mitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway.

Long-Term Connectome Analysis Reveals Reshaping of Visual, Spatial Networks in a Model With Vascular Dementia Features (2022)
Journal Article
Hall, G. R., Boehm-Sturm, P., Dirnagl, U., Finke, C., Foddis, M., Harms, C., …Farr, T. D. (2022). Long-Term Connectome Analysis Reveals Reshaping of Visual, Spatial Networks in a Model With Vascular Dementia Features. Stroke, 53(5), 1735-1745. https://doi.org/10.1161/STROKEAHA.121.036997

Background: Connectome analysis of neuroimaging data is a rapidly expanding field that offers the potential to diagnose, characterize, and predict neurological disease. Animal models provide insight into biological mechanisms that underpin disease, b... Read More about Long-Term Connectome Analysis Reveals Reshaping of Visual, Spatial Networks in a Model With Vascular Dementia Features.

Filtration performance of non- woven geotextiles with internally-stable and -unstable soils under dynamic loading (2022)
Journal Article
Khan, M. W., Dawson, A. R., & Marshall, A. M. (2022). Filtration performance of non- woven geotextiles with internally-stable and -unstable soils under dynamic loading. Geotextiles and Geomembranes, 50(2), 293-311. https://doi.org/10.1016/j.geotexmem.2021.11.007

In many applications, geotextiles are subjected to dynamic loading conditions, for example, below roads and railways, for which a Gradient Ratio (GR) test is often used to assess filtration compatibility of soil-geotextile systems. This paper present... Read More about Filtration performance of non- woven geotextiles with internally-stable and -unstable soils under dynamic loading.

Search for magnetic monopoles produced via the Schwinger mechanism (2022)
Journal Article
Acharya, B., Alexandre, J., Benes, P., Bergmann, B., Bertolucci, S., Bevan, A., …Vives, O. (2022). Search for magnetic monopoles produced via the Schwinger mechanism. Nature, 602(7895), 63-67. https://doi.org/10.1038/s41586-021-04298-1

Electrically charged particles can be created by the decay of strong enough electric fields, a phenomenon known as the Schwinger mechanism1. By electromagnetic duality, a sufficiently strong magnetic field would similarly produce magnetic monopoles,... Read More about Search for magnetic monopoles produced via the Schwinger mechanism.

Organisational development programmes and employees’ career development: the moderating role of gender (2022)
Journal Article
Pinnington, A., Aldabbas, H., Mirshahi, F., & Pirie, T. (2022). Organisational development programmes and employees’ career development: the moderating role of gender. Journal of Workplace Learning, 34(5), 466-496. https://doi.org/10.1108/JWL-08-2021-0103

Purpose:
This study aims to investigate the relationship between different organisational development programmes (360-degree feedback; Coaching; Job assignment; Employee assistance programmes; On-the-job training; Web-based career information; Cont... Read More about Organisational development programmes and employees’ career development: the moderating role of gender.