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Mapping the role of patient and public involvement during the different stages of healthcare innovation: A scoping review (2022)
Journal Article
Cluley, V., Ziemann, A., Feeley, C., Olander, E. K., Shamah, S., & Stavropoulou, C. (2022). Mapping the role of patient and public involvement during the different stages of healthcare innovation: A scoping review. Health Expectations, 25(3), 840-855. https://doi.org/10.1111/hex.13437

Background: Patient and public involvement (PPI) has become increasingly important in the development, delivery and improvement of healthcare. PPI is used in healthcare innovation; yet, how it is used has been under-reported. The aim of this scoping... Read More about Mapping the role of patient and public involvement during the different stages of healthcare innovation: A scoping review.

Requirements for and Challenges in Developing Improved Creep Ductility-based Constitutive Models for Tempered Martensitic CSEF Steels (2022)
Journal Article
Ragab, R., Parker, J., Li, M., Liu, T., Morris, A., & Sun, W. (2022). Requirements for and Challenges in Developing Improved Creep Ductility-based Constitutive Models for Tempered Martensitic CSEF Steels. Journal of Materials Research and Technology, 17, 3337-3360. https://doi.org/10.1016/j.jmrt.2022.02.047

Creep fracture behaviour of tempered martensitic steels is generally governed by the process of cavity nucleation, growth and coalescence into microcracks. Therefore, creep ductility, which can be treated as material resistance to damage, has a criti... Read More about Requirements for and Challenges in Developing Improved Creep Ductility-based Constitutive Models for Tempered Martensitic CSEF Steels.

Is oral lipid-based delivery for drug targeting to the brain feasible? (2022)
Journal Article
Brookes, A., Ji, L., Bradshaw, T. D., Stocks, M., Gray, D., Butler, J., & Gershkovich, P. (2022). Is oral lipid-based delivery for drug targeting to the brain feasible?. European Journal of Pharmaceutics and Biopharmaceutics, 172, 112-122. https://doi.org/10.1016/j.ejpb.2022.02.004

This review outlines the feasibility of oral lipid-based targeted delivery of drugs to the brain, including permeation of the central nervous system's (CNS) protective blood–brain barrier (BBB). The structure of the BBB and disruption caused by varyi... Read More about Is oral lipid-based delivery for drug targeting to the brain feasible?.

Sensory perception and consumer acceptance of commercial and salt-reduced potato crisps formulated using salt reduction design rules (2022)
Journal Article
Hurst, K. E., Hewson, L., & Fisk, I. D. (2022). Sensory perception and consumer acceptance of commercial and salt-reduced potato crisps formulated using salt reduction design rules. Food Research International, 155, Article 111022. https://doi.org/10.1016/j.foodres.2022.111022

Successful salt (NaCl) reduction strategies are required to reduce the salt content of snacks while maintaining saltiness perception and consumer acceptance. Previous research suggests that particle physicochemical design rules (small particle size,... Read More about Sensory perception and consumer acceptance of commercial and salt-reduced potato crisps formulated using salt reduction design rules.

Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer (2022)
Journal Article
Kurozumi, S., Kaira, K., Matsumoto, H., Kurosumi, M., Yokobori, T., Kanai, Y., …Horiguchi, J. (2022). Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer. Scientific Reports, 12(1), Article 2742. https://doi.org/10.1038/s41598-022-06615-8

L-type amino acid transporter 1 (LAT1), also referred to as SLC7A5, is believed to regulate tumor metabolism and be associated with tumor proliferation. In invasive breast cancer, we clinicopathologically investigated the utility of LAT1 expression.... Read More about Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer.

Transient Elastography in Community Alcohol Services: Can It Detect Significant Liver Disease and Impact Drinking Behaviour? (2022)
Journal Article
Subhani, M., Harman, D. J., Scott, R. A., Bennett, L., Wilkes, E. A., James, M. W., …Guha, I. N. (2022). Transient Elastography in Community Alcohol Services: Can It Detect Significant Liver Disease and Impact Drinking Behaviour?. Biomedicines, 10(2), Article 477. https://doi.org/10.3390/biomedicines10020477

Introduction: Alcohol is the leading cause of cirrhosis in Western populations. The early identification of high-risk drinkers followed by intervention is an effective way to reduce harm. We aim to assess the feasibility of integrating transient elas... Read More about Transient Elastography in Community Alcohol Services: Can It Detect Significant Liver Disease and Impact Drinking Behaviour?.

Using Patient and Public Involvement to Elicit Opinion on Cognitive Training Games and Assessment Technologies for Dementia (2022)
Preprint / Working Paper
Harrington, K., Craven, M. P., Wilson, M. L., & Landowska, A. Using Patient and Public Involvement to Elicit Opinion on Cognitive Training Games and Assessment Technologies for Dementia

Background:

Cognitive training and assessment technologies offer the promise of dementia risk reduction and more timely diagnosis of dementia respectively. Cognitive training technologies may help to reduce the lifetime risk of dementia by helping... Read More about Using Patient and Public Involvement to Elicit Opinion on Cognitive Training Games and Assessment Technologies for Dementia.

Therapeutic potential of miRNAs in Clostridioides difficile infection (2022)
Journal Article
Monaghan, T. M., Polytarchou, C., Kao, D., Alexander, C., & Gurnani, P. (2022). Therapeutic potential of miRNAs in Clostridioides difficile infection. Future Microbiology, 17(5), 315-318. https://doi.org/10.2217/fmb-2021-0311

Treating Clostridioides difficile infection with miRNAs alone or combined with live biotherapeutic products may augment therapeutic efficacy and help counteract drug resistance in the future.

Validation of modified GLIM criteria to predict adverse clinical outcome and response to nutritional treatment: A secondary analysis of a randomized clinical trial (2022)
Journal Article
Kaegi-Braun, N., Boesiger, F., Tribolet, P., Gomes, F., Kutz, A., Hoess, C., …Schuetz, P. (2022). Validation of modified GLIM criteria to predict adverse clinical outcome and response to nutritional treatment: A secondary analysis of a randomized clinical trial. Clinical Nutrition, 41(4), 795-804. https://doi.org/10.1016/j.clnu.2022.02.009

Background & aims: The Global Leadership Initiative on Malnutrition (GLIM) recently suggested specific criteria to standardize the diagnosis of malnutrition. There is need for validation of these criteria regarding response to nutrition treatment. Ou... Read More about Validation of modified GLIM criteria to predict adverse clinical outcome and response to nutritional treatment: A secondary analysis of a randomized clinical trial.

Non-Hermiticity: a new paradigm for model building in particle physics (2022)
Presentation / Conference Contribution
Millington, P. (2022). Non-Hermiticity: a new paradigm for model building in particle physics. Proceedings of Science, 398, Article 735. https://doi.org/10.22323/1.398.0735

Non-Hermitian quantum theories have been applied in many other areas of physics. In this note, I will briefly review recent developments in the formulation of non-Hermitian quantum field theories, highlighting features that are unique compared to Her... Read More about Non-Hermiticity: a new paradigm for model building in particle physics.

Numerical and experimental investigation of formability in incremental sheet forming of particle-reinforced metal matrix composite sheets (2022)
Journal Article
Gatea, S., Tawfiq, T. A. S., & Ou, H. (2022). Numerical and experimental investigation of formability in incremental sheet forming of particle-reinforced metal matrix composite sheets. International Journal of Advanced Manufacturing Technology, 120(3-4), 1889-1900. https://doi.org/10.1007/s00170-022-08881-2

Aluminium matrix composites (AMCs) have a high strength-to-weight ratio, high stiffness, and good damage resistance under a wide range of operating conditions, making them a viable alternative to traditional materials in a variety of technical applic... Read More about Numerical and experimental investigation of formability in incremental sheet forming of particle-reinforced metal matrix composite sheets.

Science of Learning Strategy Series: Article 3, Interleaving (2022)
Journal Article
Van Hoof, T., Sumeracki, M., & Madan, C. (2022). Science of Learning Strategy Series: Article 3, Interleaving. Journal of Continuing Education in the Health Professions, 42(4), 265-268. https://doi.org/10.1097/CEH.0000000000000418

Interleaving is an evidence-based, learning-science strategy that is relevant to the planning and implementation of continuing professional development (CPD). Mixing related but different areas of study forces the brain to reconcile the relationship... Read More about Science of Learning Strategy Series: Article 3, Interleaving.

A Geography of Infection: Spatial Processes and Patterns in Epidemics and Pandemics (2022)
Book
Smallman-Raynor, M., Cliff, A., Ord, K., & Haggett, P. (2022). A Geography of Infection: Spatial Processes and Patterns in Epidemics and Pandemics. (2nd). Oxford: Oxford University Press (OUP)

The last half century has witnessed two landmark events in medical history. The 1970s saw euphoria about the defeat of one of humankind’s oldest disease scourges with the global eradication of smallpox. To set against this, the 2020s are experiencing... Read More about A Geography of Infection: Spatial Processes and Patterns in Epidemics and Pandemics.

Rate and severity of radiological features of physical abuse in children during the first UK-wide COVID-19 enforced national lockdown (2022)
Journal Article
Stivaros, S. M., Paddock, M., Rajai, A., Cliffe, H., Connolly, D. J., Dineen, R. A., …Offiah, A. C. (2022). Rate and severity of radiological features of physical abuse in children during the first UK-wide COVID-19 enforced national lockdown. Archives of Disease in Childhood, 107(6), 575-581. https://doi.org/10.1136/archdischild-2021-323444

Objective To assess the number, type and outcome of radiological investigations for children presenting to hospital with suspected physical abuse (SPA; including abusive head trauma) during the first national COVID-19 enforced lockdown compared with... Read More about Rate and severity of radiological features of physical abuse in children during the first UK-wide COVID-19 enforced national lockdown.

The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure (2022)
Journal Article
Gordon, A. L., Rick, C., Juszczak, E., Montgomery, A., Howard, R., Guthrie, B., …Tate, V. (2022). The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure. Age and Ageing, 51(3), Article afac052. https://doi.org/10.1093/ageing/afac052

The COVID-19 pandemic resulted in catastrophic levels of morbidity and mortality for care home residents. Despite this, research platforms for COVID-19 in care homes arrived late in the pandemic compared with other care settings. The Prophylactic The... Read More about The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure.

Tract-specific statistics based on diffusion-weighted probabilistic tractography (2022)
Journal Article
Reid, A. T., Camilleri, J. A., Hoffstaedter, F., & Eickhoff, S. B. (2022). Tract-specific statistics based on diffusion-weighted probabilistic tractography. Communications Biology, 5(1), Article 138. https://doi.org/10.1038/s42003-022-03073-w

Diffusion-weighted neuroimaging approaches provide rich evidence for estimating the structural integrity of white matter in vivo, but typically do not assess white matter integrity for connections between two specific regions of the brain. Here, we p... Read More about Tract-specific statistics based on diffusion-weighted probabilistic tractography.

Terror as justice, justice as terror: counterterrorism and anti-Black racism in the United States (2022)
Journal Article
Meier, A. A. (2022). Terror as justice, justice as terror: counterterrorism and anti-Black racism in the United States. Critical Studies on Terrorism, 15(1), 83-101. https://doi.org/10.1080/17539153.2022.2031132

How do counterterrorism policies in the United States reproduce anti-Black racism? Research on U.S. domestic counterterrorism post-9/11 has largely focused on the experiences of Muslim Americans while marginalising both overlapping and separate effec... Read More about Terror as justice, justice as terror: counterterrorism and anti-Black racism in the United States.

Is it possible to implement a rare disease case-finding tool in primary care? A UK-based pilot study (2022)
Journal Article
Buendia, O., Shankar, S., Mahon, H., Toal, C., Menzies, L., Ravichandran, P., …Evans, W. (2022). Is it possible to implement a rare disease case-finding tool in primary care? A UK-based pilot study. Orphanet Journal of Rare Diseases, 17, Article 54. https://doi.org/10.1186/s13023-022-02216-w

Introduction: This study implemented MendelScan, a primary care rare disease case-finding tool, into a UK National Health Service population. Rare disease diagnosis is challenging due to disease complexity and low physician awareness. The 2021 UK Rar... Read More about Is it possible to implement a rare disease case-finding tool in primary care? A UK-based pilot study.