All Outputs (3353)

The Sherwood-Relics simulations: overview and impact of patchy reionization and pressure smoothing on the intergalactic medium (2022)
Journal Article
Puchwein, E., Bolton, J. S., Keating, L. C., Molaro, M., Gaikwad, P., Kulkarni, G., Haehnelt, M. G., Iršič, V., Šoltinský, T., Viel, M., Aubert, D., Becker, G. D., & Meiksin, A. (2023). The Sherwood-Relics simulations: overview and impact of patchy reionization and pressure smoothing on the intergalactic medium. Monthly Notices of the Royal Astronomical Society, 519(4), 6162-6183. https://doi.org/10.1093/mnras/stac3761

We present the Sherwood-Relics simulations, a new suite of large cosmological hydrodynamical simulations aimed at modelling the intergalactic medium (IGM) during and after the cosmic reionization of hydrogen. The suite consists of over 200 simulation... Read More about The Sherwood-Relics simulations: overview and impact of patchy reionization and pressure smoothing on the intergalactic medium.

Arable soil nitrogen dynamics reflect organic inputs via the extended composite phenotype (2022)
Journal Article
Neal, A. L., Barrat, H. A., Bacq-Lebreuil, A., Qin, Y., Zhang, X., Takahashi, T., …Crawford, J. W. (2023). Arable soil nitrogen dynamics reflect organic inputs via the extended composite phenotype. Nature Food, 4, 51-60. https://doi.org/10.1038/s43016-022-00671-z

Achieving food security requires resilient agricultural systems with improved nutrient-use efficiency, optimized water and nutrient storage in soils, and reduced gaseous emissions. Success relies on understanding coupled nitrogen and carbon metabolis... Read More about Arable soil nitrogen dynamics reflect organic inputs via the extended composite phenotype.

Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization (2022)
Journal Article
Damaskinaki, F. N., Jooss, N. J., Martin, E. M., Clark, J. C., Thomas, M. R., Poulter, N. S., …Slater, A. (2023). Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization. Journal of Thrombosis and Haemostasis, 21(2), 317-328. https://doi.org/10.1016/j.jtha.2022.11.002

Background: The platelet–signaling receptor glycoprotein VI (GPVI) is a promising antithrombotic target. We have previously raised a series of high-affinity nanobodies (Nbs) against GPVI and identified Nb2, Nb21, and Nb35 as potent GPVI inhibitors. T... Read More about Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial (2022)
Journal Article
Butler, C. C., Hobbs, F. D. R., Gbinigie, O. A., Rahman, N. M., Hayward, G., Richards, D. B., …Zafar, A. (2023). Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial. Lancet, 401(10373), 281-293. https://doi.org/10.1016/s0140-6736%2822%2902597-1

Background: The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19. W... Read More about Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.

Impact of Initial Population Density of the Dubas Bug, Ommatissus lybicus (Hemiptera: Tropiduchidae), on Oviposition Behaviour, Chlorophyll, Biomass and Nutritional Response of Date Palm (Phoenix dactylifera) (2022)
Journal Article
Al-Abri, N., Al-Raqami, S., Al-Hashemi, M., Al-Shidi, R., Al-Khatri, S., & Ray, R. V. (2022). Impact of Initial Population Density of the Dubas Bug, Ommatissus lybicus (Hemiptera: Tropiduchidae), on Oviposition Behaviour, Chlorophyll, Biomass and Nutritional Response of Date Palm (Phoenix dactylifera). Insects, 14(1), Article 12. https://doi.org/10.3390/insects14010012

The Dubas bug (Ommatissus lybicus) is an economically significant pest of date palms. In this study, the effect of the population density of O. lybicus on chlorophyll, measured by the soil plant analysis development (SPAD) chlorophyll meter, palm bio... Read More about Impact of Initial Population Density of the Dubas Bug, Ommatissus lybicus (Hemiptera: Tropiduchidae), on Oviposition Behaviour, Chlorophyll, Biomass and Nutritional Response of Date Palm (Phoenix dactylifera).

A Comprehensive Review of Machine-Integrated Electric Vehicle Chargers (2022)
Journal Article
Mustafa, U., Ahmed, R., Watson, A., Wheeler, P., Ahmed, N., & Dahele, P. (2023). A Comprehensive Review of Machine-Integrated Electric Vehicle Chargers. Energies, 16(1), Article 129. https://doi.org/10.3390/en16010129

Electric Vehicles are becoming increasingly popular due to their environment friendly operation. As the demand for electric vehicles increases, it has become quite important to explore their charging strategies. Since charging and traction do not nor... Read More about A Comprehensive Review of Machine-Integrated Electric Vehicle Chargers.

Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells (2022)
Journal Article
Lay, C. S., Kilpatrick, L. E., Craggs, P. D., & Hill, S. J. (2023). Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells. British Journal of Pharmacology, 180(11), 1444-1459. https://doi.org/10.1111/bph.16018

Background and Purpose: Interleukin-23 (IL-23) and its receptor are important drug targets for the treatment of auto-inflammatory diseases. IL-23 binds to a receptor complex composed of two single transmembrane spanning proteins IL23R and IL12Rβ1. In... Read More about Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells.

In-the-moment video feedback for online counselling students' role play assessment: A research note (2022)
Journal Article
Kotera, Y., Mills, D., & Taynton, K. (2022). In-the-moment video feedback for online counselling students' role play assessment: A research note. Journal of Concurrent Disorders, 15(2), 96-101. https://doi.org/10.54127/xgxs5388

Although the importance of feedback has been highlighted in education, innovative practices to improve the quality of feedback remain to be reported. Moreover, traditional text-based feedback often misses the emotional tone of feedback, therefore is... Read More about In-the-moment video feedback for online counselling students' role play assessment: A research note.

A hybrid transient CFD-thermoelectric numerical model for automobile thermoelectric generator systems (2022)
Journal Article
Luo, D., Yan, Y., Li, Y., Wang, R., Cheng, S., Yang, X., & Ji, D. (2023). A hybrid transient CFD-thermoelectric numerical model for automobile thermoelectric generator systems. Applied Energy, 332, Article 120502. https://doi.org/10.1016/j.apenergy.2022.120502

Dynamic performance prediction of the automobile thermoelectric generator system is one of the research hotspots in the field of thermoelectric technology. In this work, a hybrid transient CFD-thermoelectric numerical model is proposed for the first... Read More about A hybrid transient CFD-thermoelectric numerical model for automobile thermoelectric generator systems.

Development of a novel COMPAssion focused online psyChoTherapy for bereaved informal caregivers: the COMPACT feasibility trial protocol (2022)
Journal Article
Uneno, Y., Kotera, Y., Fujisawa, D., Kataoka, Y., Kosugi, K., Murata, N., Kessoku, T., Ozaki, A., Miyatake, H., & Muto, M. (2022). Development of a novel COMPAssion focused online psyChoTherapy for bereaved informal caregivers: the COMPACT feasibility trial protocol. BMJ Open, 12(12), e067187. https://doi.org/10.1136/bmjopen-2022-067187

Introduction An easy-to-access and effective psychotherapy for bereaved informal caregivers has not been established. People with higher self-compassion status tend to have lower bereavement related grief, psychotherapy focused on self-compassion can... Read More about Development of a novel COMPAssion focused online psyChoTherapy for bereaved informal caregivers: the COMPACT feasibility trial protocol.

Assessment of the accuracy of low-cost multi-GNSS receivers in monitoring dynamic response of structures (2022)
Journal Article
Xue, C., Psimoulis, P., Horsfall, A., Zhang, Q., & Meng, X. (2022). Assessment of the accuracy of low-cost multi-GNSS receivers in monitoring dynamic response of structures. Applied Geomatics, https://doi.org/10.1007/s12518-022-00482-8

The monitoring of bridges is a crucial operation for their structural health examination and maintenance. GNSS technology is one of the methods which are applied with the main advantage that the direct measurement of the bridge displacement is conduc... Read More about Assessment of the accuracy of low-cost multi-GNSS receivers in monitoring dynamic response of structures.

Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration (2022)
Journal Article
Suzuki, A., Tillmann, H., Williams, J., Hauser, R. G., Frund, J., Suzuki, M., Prior, F., Aithal, G. P., Lucena, M. I., Andrade, R. J., Tong, W., & Hunt, C. M. (2023). Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration. Drug Safety, 46(2), 129-143. https://doi.org/10.1007/s40264-022-01255-3

Introduction
Drug-induced liver injury is a significant health issue, yet the exposure-based incidence remains to be characterized.

Objective
We aimed to assess the frequency, phenotypes, and outcomes of acute liver injury associated with amoxi... Read More about Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration.

Tasering Twin Soft Robot: A Multimodal Soft Robot Capable of Passive Flight and Wall Climbing (2022)
Journal Article
Sriratanasak, N., Axinte, D., Dong, X., Mohammad, A., Russo, M., & Raimondi, L. (2022). Tasering Twin Soft Robot: A Multimodal Soft Robot Capable of Passive Flight and Wall Climbing. Advanced Intelligent Systems, 4(12), Article 2200223. https://doi.org/10.1002/aisy.202200223

The application of Soft Crawling Robots (SCRs) to real-world scenarios remains a grand challenge due to their limited deployment time to reach the target and accessibility to difficult-to-reach environments by any obstacles. To overcome these limitat... Read More about Tasering Twin Soft Robot: A Multimodal Soft Robot Capable of Passive Flight and Wall Climbing.

Autism, Attachment, and Alexithymia: Investigating Emoji Comprehension (2022)
Journal Article
Taylor, H., Hand, C. J., Howman, H., & Filik, R. (2024). Autism, Attachment, and Alexithymia: Investigating Emoji Comprehension. International Journal of Human-Computer Interaction, 40(9), 2211-2224. https://doi.org/10.1080/10447318.2022.2154890

Emoji are often misinterpreted. This study investigated whether individual differences known to impact facial emotion recognition would also affect emoji recognition. Participants completed an online emoji classification task, and then completed ques... Read More about Autism, Attachment, and Alexithymia: Investigating Emoji Comprehension.

Prisoner Death Investigations: Setting the Agenda for Change (2022)
Journal Article
Tomczak, P., & McAllister, S. (2022). Prisoner Death Investigations: Setting the Agenda for Change. Prison Service Journal, 32-38

Development of two transient models for predicting dynamic response characteristics of an automobile thermoelectric generator system (2022)
Journal Article
Luo, D., Zhao, Y., Yan, Y., Chen, H., Chen, W.-H., Wang, R., …Yang, X. (2023). Development of two transient models for predicting dynamic response characteristics of an automobile thermoelectric generator system. Applied Thermal Engineering, 221, Article 119793. https://doi.org/10.1016/j.applthermaleng.2022.119793

In this work, two transient models, including a transient fluid-thermal-electric multiphysics numerical model and a hybrid transient CFD-analytical model, are proposed to predict the dynamic performance of the automobile thermoelectric generator syst... Read More about Development of two transient models for predicting dynamic response characteristics of an automobile thermoelectric generator system.

Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study (2022)
Journal Article
Labree, B., Hoare, D. J., Fackrell, K., Hall, D. A., Gascoyne, L. E., & Sereda, M. (2022). Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study. Trials, 23(1), Article 1039. https://doi.org/10.1186/s13063-022-07020-2

Background: Tinnitus is the awareness of a sound in the ear or head in the absence of an external source. It affects around 10–15% of people and current treatment options are limited. Experimental treatments include various forms of electrical stimul... Read More about Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study.

Immersive, Creative, Inclusive: Areas of cross-fertilization between accessible captions for D/deaf audiences for the stage and for the screen (2022)
Journal Article
Mével, P. A., Robinson, J., & Tennent, P. (2022). Immersive, Creative, Inclusive: Areas of cross-fertilization between accessible captions for D/deaf audiences for the stage and for the screen. Journal of Audiovisual Translation, 5(2), 176-193. https://doi.org/10.47476/jat.v5i2.2022.227

In a deliberate and valiant effort to adapt to the conditions created by the recent pandemic, many theatre companies across the globe shifted their activities from the stage to online video platforms. But in releasing large portions of their back-cat... Read More about Immersive, Creative, Inclusive: Areas of cross-fertilization between accessible captions for D/deaf audiences for the stage and for the screen.

A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation (2022)
Journal Article
Huggett, Z. J., Smith, A., De Vivo, N., Gomez, D., Jethwa, P., Brameld, J. M., …Salter, A. M. (2022). A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation. Nutrients, 15(1), Article 40. https://doi.org/10.3390/nu15010040

Non-alcoholic fatty liver disease (NAFLD) begins with lipid accumulation within hepatocytes, but the relative contributions of different macronutrients is still unclear. We investigated the impact of fatty acids, glucose and fructose on lipid accumul... Read More about A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation.

Genome Reference Assembly for Bottlenecked Southern Australian Koalas (2022)
Journal Article
Blanchard, A. M., Emes, R. D., Greenwood, A. D., Holmes, N., Loose, M. W., McEwen, G. K., …Tarlinton, R. E. (2023). Genome Reference Assembly for Bottlenecked Southern Australian Koalas. Genome Biology and Evolution, 15(1), Article evac176. https://doi.org/10.1093/gbe/evac176

Koala populations show marked differences in inbreeding levels and in the presence or absence of the endogenous Koala retrovirus (KoRV). These genetic differences among populations may lead to severe disease impacts threatening koala population viabi... Read More about Genome Reference Assembly for Bottlenecked Southern Australian Koalas.