All Outputs (4613)

Exploring the current and future role of the pharmacists in osteoporosis screening and management in Malaysia (2018)
Journal Article
Toh, L., Lai, P., Othman, S., Shah, A., Dang, C., Low, B., …Anderson, C. (2018). Exploring the current and future role of the pharmacists in osteoporosis screening and management in Malaysia. International Journal of Clinical Pharmacy, 40(2), 450-457. https://doi.org/10.1007/s11096-018-0597-9

Background Several studies have found that pharmacists can assist in screening and prevention of osteoporosis by referring patients for bone mineral density scans and counselling on lifestyle changes. In Malaysia, screening osteoporosis in all elderl... Read More about Exploring the current and future role of the pharmacists in osteoporosis screening and management in Malaysia.

Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays (2018)
Journal Article
Sanna, M., Sicilia, G., Alazzo, A., Singh, N., Musumeci, F., Schenone, S., …Alexander, C. (in press). Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays. ACS Medicinal Chemistry Letters, 9(3), https://doi.org/10.1021/acsmedchemlett.7b00456

A miniaturized assay was optimized to evaluate the enhanced apparent water solubility of pyrazolo[3,4-d]pyrimidine derivatives used extensively as anticancer drug scaffolds. The applied amount of drugs used in the reported strategy ranged from 5-10 μ... Read More about Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays.

Prototypical actions with objects are more easily imagined than atypical actions (2018)
Journal Article
Madan, C. R., Ng, A., & Singhal, A. (2018). Prototypical actions with objects are more easily imagined than atypical actions. Journal of Cognitive Psychology, 30(3), 314-320. https://doi.org/10.1080/20445911.2018.1429448

© 2018 Informa UK Limited, trading as Taylor & Francis Group. Tool use is an important facet of everyday life, though sometimes it is necessary to use tools in ways that do not fit within their typical functions. Here we asked participants to imagi... Read More about Prototypical actions with objects are more easily imagined than atypical actions.

Nanopore sequencing and assembly of a human genome with ultra-long reads (2018)
Journal Article
Jain, M., Koren, S., Miga, K., Quick, J., Rand, A., Sasani, T., …Loose, M. (2018). Nanopore sequencing and assembly of a human genome with ultra-long reads. Nature Biotechnology, 36(4), 338-345. https://doi.org/10.1038/nbt.4060

© 2018 Nature Publishing Group. All rights reserved. We report the sequencing and assembly of a reference genome for the human GM12878 Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore sequencer. 91.2 Gb of sequence data, r... Read More about Nanopore sequencing and assembly of a human genome with ultra-long reads.

“There are more important things to worry about”:attitudes and behaviours towards leisure noise and use ofhearing protection in young adults (2018)
Journal Article
Hunter, A. (2018). “There are more important things to worry about”:attitudes and behaviours towards leisure noise and use ofhearing protection in young adults. International Journal of Audiology, 57(6), 449-456. https://doi.org/10.1080/14992027.2018.1430383

Objective: Noise-induced hearing problems among young adults are increasing due to participation in activities where music is played at a loud volume. This study explored attitudes towards leisure noise, hearing protection, and perceived susceptibili... Read More about “There are more important things to worry about”:attitudes and behaviours towards leisure noise and use ofhearing protection in young adults.

Social strategy to gain knowledge for innovation (2018)
Journal Article
Candi, M., Roberts, D. L., Tucker, M., & Barczak, G. (2018). Social strategy to gain knowledge for innovation. British Journal of Management, 29(4), 731-749. https://doi.org/10.1111/1467-8551.12280

Taking the knowledge-based view of the firm as its starting point, and acknowledging that knowledge can lie outside the firm, this research extends our understanding of how the growing social media trend can contribute to open innovation. We specific... Read More about Social strategy to gain knowledge for innovation.

Non-asymptotic analysis of quantum metrology protocols beyond the Cramér-Rao bound (2018)
Journal Article
Rubio Jiménez, J., Knott, P., & Dunningham, J. A. (2018). Non-asymptotic analysis of quantum metrology protocols beyond the Cramér-Rao bound. Journal of Physics Communications, 2, Article 015027. https://doi.org/10.1088/2399-6528/aaa234

Many results in the quantum metrology literature use the Cramér-Rao bound and the Fisher information to compare different quantum estimation strategies. However, there are several assumptions that go into the construction of these tools, and these li... Read More about Non-asymptotic analysis of quantum metrology protocols beyond the Cramér-Rao bound.

Space vectors and pseudo inverse matrix methods for the radial force control in bearingless multi-sector permanent magnet machines (2018)
Journal Article
Sala, G., Valente, G., Formentini, A., Papini, L., Gerada, D., Zanchetta, P., …Gerada, C. (2018). Space vectors and pseudo inverse matrix methods for the radial force control in bearingless multi-sector permanent magnet machines. IEEE Transactions on Industrial Electronics, 65(9), 6912-6922. https://doi.org/10.1109/TIE.2018.2795590

Two different approaches to characterize the torque and radial force production in a Bearingless Multi-Sector Permanent Magnet (BMSPM) machine are presented in this work. The first method consists of modelling the motor in terms of torque and force p... Read More about Space vectors and pseudo inverse matrix methods for the radial force control in bearingless multi-sector permanent magnet machines.

Alien honeybees increase pollination risks for range-restricted plants (2018)
Journal Article
Norfolk, O., Gilbert, F., & Eichhorn, M. P. (2018). Alien honeybees increase pollination risks for range-restricted plants. Diversity and Distributions, 24(5), 705-713. https://doi.org/10.1111/ddi.12715

Aim:Range-restricted species are of high conservation concern and the way in which they interact with more widespread species has implications for their persistence. Here we determine how the specialisation of mutualistic interactions varies with res... Read More about Alien honeybees increase pollination risks for range-restricted plants.

Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor (2018)
Journal Article
Whittaker, S. R., Barlow, C., Martin, M. P., Mancusi, C., Wagner, S., Self, A., …Workman, P. (in press). Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor. Molecular Oncology, 12(3), https://doi.org/10.1002/1878-0261.12148

Deregulation of the cyclin-dependent kinases (CDKs) has been implicated in the pathogenesis of multiple cancer types. Consequently, CDKs have garnered intense interest as therapeutic targets for the treatment of cancer. We describe herein the molecul... Read More about Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa (2018)
Journal Article
Soukarieh, F., Vico Oton, E., Dubern, J.-F., Gomes, J., Halliday, N., de Pilar Crespo, M., …Cámara, M. (2018). In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa. Molecules, 23(2), 1-15. https://doi.org/10.3390/molecules23020257

Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis, wound and nosocomial infections, posing a serious burden to public health, due to its antibiotic resistance. The P. aeruginosa Pseudomonas Quinolone System (pqs) quorum sens... Read More about In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa.

Impact of mechanical bowel preparation in elective colorectal surgery: a meta-analysis (2018)
Journal Article
Rollins, K. E., Javanmard-Emamghissi, H., & Lobo, D. N. (in press). Impact of mechanical bowel preparation in elective colorectal surgery: a meta-analysis. World Journal of Gastroenterology, 24(4), https://doi.org/10.3748/wjg.v24.i4.519

AIM: To analyse the effect of mechanical bowel preparation vs no mechanical bowel preparation on outcome in patients undergoing elective colorectal surgery.
METHODS: Meta-analysis of randomised controlled trials and observational studies comparing a... Read More about Impact of mechanical bowel preparation in elective colorectal surgery: a meta-analysis.

Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia (2018)
Journal Article
O'Sullivan, S. A., O'Sullivan, C., Healy, L. M., Dev, K. K., & Sheridan, G. K. (2018). Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia. Journal of Neurochemistry, 144(6), 736-747. https://doi.org/10.1111/jnc.14313

© 2018 International Society for Neurochemistry. Sphingosine 1-phosphate receptors (S1PR) are G protein-coupled and compose a family with five subtypes, S1P1R–S1P5R. The drug Gilenya ® (Novartis, Basel, Switzerland) (Fingolimod; FTY720) targets S1PRs... Read More about Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia.

Allowance for boundary sharpening in the determination of diffusion coefficients by sedimentation velocity: a historical perspective. (2018)
Journal Article

This review summarizes endeavors undertaken in the middle of last century to employ the Lamm equation for quantitative analysis of boundary spreading in sedimentation velocity experiments on globular proteins, thereby illustrating the ingenuity requi... Read More about Allowance for boundary sharpening in the determination of diffusion coefficients by sedimentation velocity: a historical perspective..

Building accountability into the Internet of Things: the IoT Databox model (2018)
Journal Article
Crabtree, A., Lodge, T., Colley, J., Greenhalgh, C., Glover, K., Haddadi, H., …McAuley, D. (2018). Building accountability into the Internet of Things: the IoT Databox model. Journal of Reliable Intelligent Environments, 4(1), 39-55. https://doi.org/10.1007/s40860-018-0054-5

© 2018, The Author(s). This paper outlines the IoT Databox model as a means of making the Internet of Things (IoT) accountable to individuals. Accountability is a key to building consumer trust and is mandated by the European Union’s general data pro... Read More about Building accountability into the Internet of Things: the IoT Databox model.

Price adjustment in currency unions: another dimension to the endogeneity of the optimum currency area criteria? (2018)
Journal Article
Bleaney, M., & Yin, L. (2018). Price adjustment in currency unions: another dimension to the endogeneity of the optimum currency area criteria?. Oxford Bulletin of Economics and Statistics, 80(4), 788-803. https://doi.org/10.1111/obes.12235

In a rational expectations model, wages and prices should respond more to shocks in currency unions than under adjustable pegs because of the absence of exchange rate adjustment. This is an aspect of the endogeneity of the optimum currency area crite... Read More about Price adjustment in currency unions: another dimension to the endogeneity of the optimum currency area criteria?.

Investigation of a Surface PM Machine With Segmented-Eccentric Magnet Poles (2018)
Journal Article
Jing, L., Luo, Z., Qu, R., Kong, W., Gao, Y., Huang, H., & Shah, M. R. (2018). Investigation of a Surface PM Machine With Segmented-Eccentric Magnet Poles. IEEE Transactions on Applied Superconductivity, 28(3), 1-5. https://doi.org/10.1109/TASC.2018.2798601

This paper proposes a novel machine with segmented permanent magnets (PM) poles and optimized Halbach array having different eccentricities, i.e., the inner and outer arcs of the segmented PM have different centers. The electromagnetic property of th... Read More about Investigation of a Surface PM Machine With Segmented-Eccentric Magnet Poles.

Introduction (2018)
Book Chapter
Spence, L. J., Frynas, J. G., Muthuri, J. N., & Navare, J. (2018). Introduction. In L. J. Spence, J. G. Frynas, J. N. Muthuri, & J. Navare (Eds.), Research Handbook on Small Business Social Responsibility: Global Perspectives (1-19). Cheltenham, UK: Edward Elgar Publishing

Commutativity of the strain energy density expression for the benefit of the FEM implementation of Koiter's initial postbuckling theory (2018)
Journal Article
Li, S., Yan, J., Zhang, G., & Duan, S. (2018). Commutativity of the strain energy density expression for the benefit of the FEM implementation of Koiter's initial postbuckling theory. International Journal for Numerical Methods in Engineering, 114(9), 955-974. https://doi.org/10.1002/nme.5772

Copyright © 2018 John Wiley & Sons, Ltd. The concept of full commutativity of displacements in the expression for strain energy density for the geometrically nonlinear problem has been introduced for the first time and fully established in this pap... Read More about Commutativity of the strain energy density expression for the benefit of the FEM implementation of Koiter's initial postbuckling theory.

Vascular endothelial growth factor-A165b restores normal glomerular water permeability in a diphtheria-toxin mouse model of glomerular injury (2018)
Journal Article
Stevens, M., Neal, C. R., Salmon, A. H., Bates, D. O., Harper, S. J., & Oltean, S. (in press). Vascular endothelial growth factor-A165b restores normal glomerular water permeability in a diphtheria-toxin mouse model of glomerular injury. Nephron, https://doi.org/10.1159/000485664

BACKGROUND/AIMS:Genetic cell ablation using the human diphtheria toxin receptor (hDTR) is a new strategy used for analysing cellular function. Diphtheria toxin (DT) is a cytotoxic protein that leaves mouse cells relatively unaffected, but upon bindin... Read More about Vascular endothelial growth factor-A165b restores normal glomerular water permeability in a diphtheria-toxin mouse model of glomerular injury.