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Unusual and tunable negative linear compressibility in the metal–organic framework MFM-133(M)(M = Zr, Hf) (2018)
Journal Article
Yan, Y., O'Connor, A. E., Kanthasamy, G., Atkinson, G., Allan, D. R., Blake, A. J., & Schröder, M. (in press). Unusual and tunable negative linear compressibility in the metal–organic framework MFM-133(M)(M = Zr, Hf). Journal of the American Chemical Society, https://doi.org/10.1021/jacs.7b11747

High pressure single-crystal X-ray structural analyses of isostructural MFM-133(M) (M = Zr, Hf) of flu topology and incorporating the tetracarboxylate ligand TCHB4– [H4TCHB = 3,3',5,5'-tetrakis(4-carboxyphenyl)-2,2',4,4',6,6'-hexamethyl-1,1'-biphenyl... Read More about Unusual and tunable negative linear compressibility in the metal–organic framework MFM-133(M)(M = Zr, Hf).

Evaluating attitudes to safety leadership within rail construction projects (2018)
Journal Article
Stiles, S., Ryan, B., & Golightly, D. (2018). Evaluating attitudes to safety leadership within rail construction projects. Safety Science, 110(B), 134-144. https://doi.org/10.1016/j.ssci.2017.12.030

© 2018 Elsevier Ltd Safety leadership is widely discussed, commonly relating to improving safety performance within an occupational environment. Whilst there is considerable research on the characteristics of positive and negative safety leadership b... Read More about Evaluating attitudes to safety leadership within rail construction projects.

Mendelian adult-onset leukodystrophy genes in Alzheimer´s disease. Critical influence of CSF1R and NOTCH3 (2018)
Journal Article
Sassi, C., Nalls, M., Ridge, P., Gibbs, R., Lupton, M., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K., Medway, C., Lord, J., Turton, J., Bras, J., Blumenau, S., Thielke, M., Josties, C., Freyer, D., Dietrich, A., Hammer, M., Baier, M., …Hardy, J. (in press). Mendelian adult-onset leukodystrophy genes in Alzheimer´s disease. Critical influence of CSF1R and NOTCH3. Neurobiology of Aging, 66, Article 179.e17-179.e29. https://doi.org/10.1016/j.neurobiolaging.2018.01.015

Mendelian adult-onset leukodystrophies are a spectrum of rare inherited progressive neurodegenerative disorders affecting the white matter of the central nervous system. Among these, Cerebral Autosomal Dominant and Recessive Arteriopathy with Subcort... Read More about Mendelian adult-onset leukodystrophy genes in Alzheimer´s disease. Critical influence of CSF1R and NOTCH3.

The history of language learning and teaching in Britain (2018)
Journal Article
McLelland, N. (2018). The history of language learning and teaching in Britain. Language Learning Journal, 46(1), 6-16. https://doi.org/10.1080/09571736.2017.1382052

This article provides an overview, based on the most recent research available, of the history of language learning and teaching (HoLLT) in Britain. After an overview of the state of research, we consider which languages have been learnt, why, and ho... Read More about The history of language learning and teaching in Britain.

Bayesian nonparametrics for stochastic epidemic models (2018)
Journal Article
Kypraios, T., & O'Neill, P. D. (2018). Bayesian nonparametrics for stochastic epidemic models. Statistical Science, 33(1), https://doi.org/10.1214/17-STS617

The vast majority of models for the spread of communicable diseases are parametric in nature and involve underlying assumptions about how the disease spreads through a population. In this article we consider the use of Bayesian nonparametric approach... Read More about Bayesian nonparametrics for stochastic epidemic models.

Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC (2018)
Journal Article
Kaewkangsadan, V., Verma, C., Eremin, J. M., Cowley, G. P., Ilyas, M., & Eremin, O. (2018). Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC. BMC Cancer, 18, Article 123. https://doi.org/10.1186/s12885-018-4044-z

Background

The tumour microenvironment consists of malignant cells, stroma and immune cells. In women with large and locally advanced breast cancers (LLABCs) undergoing neoadjuvant chemotherapy (NAC), tumour-infiltrating lymphocytes (TILs), variou... Read More about Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC.

Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis (2018)
Journal Article
Herrod, P. J., Doleman, B., Blackwell, J. E., O’Boyle, F., Williams, J. P., Lund, J. N., & Phillips, B. E. (in press). Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis. Journal of the American Society of Hypertension, 12(4), https://doi.org/10.1016/j.jash.2018.01.008

The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from st... Read More about Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis.

Imperial careering and enslavement in the long eighteenth-century: the Bentinck family, 1710-1830s (2018)
Journal Article
Haggerty, S., & Seymour, S. (2018). Imperial careering and enslavement in the long eighteenth-century: the Bentinck family, 1710-1830s. Slavery and Abolition, 39(4), 642-662. https://doi.org/10.1080/0144039X.2018.1429190

This paper examines the claims of Eric Williams and the more recent Legacies of British Slave-Ownership projects regarding the influence of enslavement in the building of Britain and its empire through a multi-generational study of a leading British... Read More about Imperial careering and enslavement in the long eighteenth-century: the Bentinck family, 1710-1830s.

BQ323636.1, a novel splice variant to NCOR2, as a predictor for tamoxifen resistant breast cancer (2018)
Journal Article
Gong, C., Man, E. P., Tsoi, H., Lee, T. K., Paul, L., Mak, S.-T., …Khoo, U.-S. (2018). BQ323636.1, a novel splice variant to NCOR2, as a predictor for tamoxifen resistant breast cancer. Clinical Cancer Research, 24(15), 3681-3691. https://doi.org/10.1158/1078-0432.CCR-17-2259

Purpose: Adjuvant tamoxifen treatment revolutionized the management of estrogen receptor (ER) positive breast cancers to prevent cancer recurrence; however drug resistance compromises its clinical efficacy. The mechanisms underlying tamoxifen resista... Read More about BQ323636.1, a novel splice variant to NCOR2, as a predictor for tamoxifen resistant breast cancer.

The influence of multinational enterprises on subsidiaries: context matters (2018)
Journal Article
Egbe, I., Adegbite, E., & Yekini, K. C. (2018). The influence of multinational enterprises on subsidiaries: context matters. Accounting, Auditing and Accountability Journal, 31(2), https://doi.org/10.1108/AAAJ-06-2016-2608

Purpose: This paper examines how differences in the institutional environment of a multinational enterprise (MNE) shape the role of management control systems (MCSs) and social capital in the headquarters-subsidiary relationship of an emerging econom... Read More about The influence of multinational enterprises on subsidiaries: context matters.

A Genome-Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos (2018)
Journal Article
Burkart, K. M., Sofer, T., London, S. J., Manichaikul, A., Hartwig, F. P., Yan, Q., …Barr, R. G. (2018). A Genome-Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos. American Journal of Respiratory and Critical Care Medicine, 198(2), 208-219. https://doi.org/10.1164/rccm.201707-1493OC

Rationale: Lung function and chronic obstructive pulmonary disease (COPD) are heritable traits. Genome-wide association studies (GWAS) have identified numerous pulmonary function and COPD loci, primarily in cohorts of European ancestry.
Objectives:... Read More about A Genome-Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.

On the complexity of resource-bounded logics (2018)
Journal Article
Alechina, N., Bulling, N., Demri, S., & Logan, B. S. (2018). On the complexity of resource-bounded logics. Theoretical Computer Science, 750, 69-100. https://doi.org/10.1016/j.tcs.2018.01.019

We revisit decidability results for resource-bounded logics and use decision problems on vector addition systems with states (VASS) in order to establish complexity characterisations of (decidable) model checking problems. We show that the model chec... Read More about On the complexity of resource-bounded logics.

Targeting ataxia telangiectasia mutated and Rad3 related kinase (ATR) in PTEN deficient breast cancers for personalized therapy (2018)
Journal Article
Al-Subhi, N., Ali, R., Abdel-Fatah, T., Moseley, P. M., Chan, S. Y., Green, A. R., Ellis, I. O., Rakha, E., & Madhusudan, S. (2018). Targeting ataxia telangiectasia mutated and Rad3 related kinase (ATR) in PTEN deficient breast cancers for personalized therapy. Breast Cancer Research and Treatment, 169(2), 277–286. https://doi.org/10.1007/s10549-018-4683-4

Purpose: PTEN, a negative regulator of PI3K signaling, is involved in DNA repair. ATR is a key sensor of DNA damage and replication stress. We evaluated whether ATR signaling has clinical significance and could be targeted by synthetic lethality in P... Read More about Targeting ataxia telangiectasia mutated and Rad3 related kinase (ATR) in PTEN deficient breast cancers for personalized therapy.

Fuzzy C-means-based scenario bundling for stochastic service network design (2018)
Presentation / Conference Contribution
Jiang, X., Bai, R., Landa-Silva, D., & Aickelin, U. (2018). Fuzzy C-means-based scenario bundling for stochastic service network design. In 2017 IEEE Symposium Series on Computational Intelligence, SSCI 2017 - Proceedings (1-8). https://doi.org/10.1109/SSCI.2017.8280905

Stochastic service network designs with uncertain demand represented by a set of scenarios can be modelled as a large-scale two-stage stochastic mixed-integer program (SMIP). The progressive hedging algorithm (PHA) is a decomposition method for solvi... Read More about Fuzzy C-means-based scenario bundling for stochastic service network design.

“World Community Interest” Approach to Interim Measures on “Robot Weapons”: Revisiting the Nuclear Test Cases (2018)
Journal Article
Ulgen, O. (2018). “World Community Interest” Approach to Interim Measures on “Robot Weapons”: Revisiting the Nuclear Test Cases. New Zealand Yearbook of International Law, 14(2016), 3-34. https://doi.org/10.1163/9789004345911_002

Forty-four years after the ICJ provisional measures orders in the Nuclear Test Cases requesting France stop atmospheric nuclear weapons testing in the South Pacific, we are facing another deadly threat from the use and development of "robot weapons".... Read More about “World Community Interest” Approach to Interim Measures on “Robot Weapons”: Revisiting the Nuclear Test Cases.

Oral green tea catechins do not provide photoprotection from direct DNA damage induced by higher dose solar simulated radiation: A randomized controlled trial (2018)
Journal Article
Farrar, M. D., Huq, R., Mason, S., Nicolaou, A., Clarke, K. A., Dew, T. P., …Rhodes, L. E. (2018). Oral green tea catechins do not provide photoprotection from direct DNA damage induced by higher dose solar simulated radiation: A randomized controlled trial. Journal of The American Academy of Dermatology, 78(2), 414-416. https://doi.org/10.1016/j.jaad.2017.08.021

Enhancing the potential of enantioselective organocatalysis with light (2018)
Journal Article
Melchiorre, P., & Silvi, M. (2018). Enhancing the potential of enantioselective organocatalysis with light. Nature, 554(7690), 41-49. https://doi.org/10.1038/nature25175

© 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Organocatalysis - catalysis mediated by small chiral organic molecules - is a powerful technology for enantioselective synthesis, and has extensive applications in tra... Read More about Enhancing the potential of enantioselective organocatalysis with light.