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Enhancing the potential of enantioselective organocatalysis with light (2018)
Journal Article
Melchiorre, P., & Silvi, M. (2018). Enhancing the potential of enantioselective organocatalysis with light. Nature, 554(7690), 41-49. https://doi.org/10.1038/nature25175

© 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Organocatalysis - catalysis mediated by small chiral organic molecules - is a powerful technology for enantioselective synthesis, and has extensive applications in tra... Read More about Enhancing the potential of enantioselective organocatalysis with light.

Preface (2018)
Journal Article
Hanzalek, Z., Kendall, G., McCollum, B., Sucha, P., & Berghe, G. V. (2018). Preface. Journal of Scheduling, 21, 129-130. https://doi.org/10.1007/s10951-018-0557-1

This is a Preface to a special of the journal that contains 8 selected papers from the 2015 Multidisciplinary International Scheduling Conference: Theory and Applications (MISTA) that was held in Prague, Czech Republic (25–28 August 2015).

Hyperacusis: major research questions (2018)
Journal Article
Baguley, D. M., & Hoare, D. J. (2018). Hyperacusis: major research questions. HNO, 66(5), 358-363. https://doi.org/10.1007/s00106-017-0464-3

Background: Hyperacusis is a troublesome symptom that can have a marked negative impact on quality of life. Objectives: To identify major research questions in hyperacusis. Materials and methods: Review of gaps in knowledge regarding hyperacusis, a... Read More about Hyperacusis: major research questions.

Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial (2018)
Journal Article
Dineen, R. A., Pszczolkowski, S., Flaherty, K., Law, Z. K., Morgan, P. S., Roberts, I., …Sprigg, N. (in press). Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial. BMJ Open, 8(2), Article e019930. https://doi.org/10.1136/bmjopen-2017-019930

Objectives: To test whether administration of the antifibrinolytic drug tranexamic acid (TXA) in patients with spontaneous intracerebral haemorrhage (SICH) leads to increased prevalence of diffusion-weighted MRI defined hyperintense ischaemic lesions... Read More about Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial.

Creep behaviour of inconel 718 processed by laser powder bed fusion (2018)
Journal Article
Xu, Z., Hyde, C., Tuck, C., & Clare, A. (2018). Creep behaviour of inconel 718 processed by laser powder bed fusion. Journal of Materials Processing Technology, 256, https://doi.org/10.1016/j.jmatprotec.2018.01.040

Additive manufacturing lends itself well to the manufacture of aerospace parts due to the high complexity and small volume of many components found in modern aero engines. By exploiting additive manufacturing design freedoms, enhanced part functional... Read More about Creep behaviour of inconel 718 processed by laser powder bed fusion.

γ-rays irradiation effects on dielectric properties of Ti/Au/GaAsN Schottky diodes with 1.2%N (2018)
Journal Article
Teffahi, A., Hamri, D., Djeghlouf, A., Abboun Abid, M., Saidane, A., Al Saqri, N., …henini, M. (2018). γ-rays irradiation effects on dielectric properties of Ti/Au/GaAsN Schottky diodes with 1.2%N. Radiation Physics and Chemistry, 147, https://doi.org/10.1016/j.radphyschem.2018.01.029

Dielectric properties of As grown and irradiated Ti /Au/GaAsN Schottky diodes with 1.2%N are investigated using capacitance/conductance-voltage measurements in 90–290 K temperature range and 50–2000 kHz frequency range. Extracted parameters are inter... Read More about γ-rays irradiation effects on dielectric properties of Ti/Au/GaAsN Schottky diodes with 1.2%N.

Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’ (2018)
Journal Article
Scutt, P., Appleton, J. P., Dixon, M., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., …Bath, P. M. (2018). Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’. European Stroke Journal, 3(2), 193-196. https://doi.org/10.1177/2396987318756696

Rationale: Glyceryl trinitrate, a nitric oxide donor, is a candidate treatment for acute stroke; it lowers blood pressure, does not alter cerebral blood flow or platelet function and is neuroprotective in experimental stroke. The ongoing rapid interv... Read More about Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’.

Generation of a localised microwave magnetic field by coherent phonons in a ferromagnetic grating (2018)
Journal Article
Salasyuk, A., Rudkovskaya, A., Danilov, A., Glavin, B., Kukhtaruk, S., Wang, M., …Scherbakov, A. (2018). Generation of a localised microwave magnetic field by coherent phonons in a ferromagnetic grating. Physical Review B, 97(6), Article 060404. https://doi.org/10.1103/PhysRevB.97.060404

A high-amplitude microwave magnetic field localized at the nanoscale is a desirable tool for various applications within the rapidly developing field of nanomagnetism. Here, we drive magnetization precession by coherent phonons in a metal ferromagnet... Read More about Generation of a localised microwave magnetic field by coherent phonons in a ferromagnetic grating.

Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells (2018)
Journal Article
Petrova, R. S., Webb, K. F., Vaghefi, E., Walker, K., Schey, K. L., & Donaldson, P. J. (2018). Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells. American Journal of Physiology - Cell Physiology, 314(2), C191-C201. https://doi.org/10.1152/ajpcell.00214.2017

Although the functionality of the lens water channels aquaporin 1 (AQP1; epithelium) and AQP0 (fiber cells) is well established, less is known about the role of AQP5 in the lens. Since in other tissues AQP5 functions as a regulated water channel with... Read More about Dynamic functional contribution of the water channel AQP5 to the water permeability of peripheral lens fiber cells.

Targeting gp100 and TRP-2 with a DNA vaccine: incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial (2018)
Journal Article
Patel, P. M., Ottensmeier, C. H., Mulatero, C., Lorigan, P., Plummer, R., Pandha, H. S., …Durrant, L. (2018). Targeting gp100 and TRP-2 with a DNA vaccine: incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial. OncoImmunology, 7(6), Article e1433516. https://doi.org/10.1080/2162402X.2018.1433516

A DNA vaccine, SCIB1, incorporating two CD8 and two CD4 epitopes from TRP-2/gp100 was evaluated in patients with metastatic melanoma. Each patient received SCIB1 via intramuscular injection with electroporation. The trial was designed to find the saf... Read More about Targeting gp100 and TRP-2 with a DNA vaccine: incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical outcome in a phase I/II trial.

Active search for computer-aided drug design (2018)
Journal Article
Oglic, D., Oatley, S. A., Macdonald, S. J., McInally, T., Garnett, R., Hirst, J. D., & Gärtner, T. (in press). Active search for computer-aided drug design. Molecular Informatics, 37, https://doi.org/10.1002/minf.201700130

We consider lead discovery as active search in a space of labelled graphs. In particular, we extend our recent data-driven adaptive Markov chain approach, and evaluate it on a focused drug design problem, where we search for an antagonist of an av in... Read More about Active search for computer-aided drug design.

Expansion of the 'Antibiotic Guardian' one health behavioural campaign across Europe to tackle antibiotic resistance: pilot phase and analysis of AMR knowledge (2018)
Journal Article
Newitt, S., Anthierens, S., Coenen, S., Lo Fo Wong, D., Salvi, C., Puleston, R., & Ashiru-Oredope, D. (2018). Expansion of the 'Antibiotic Guardian' one health behavioural campaign across Europe to tackle antibiotic resistance: pilot phase and analysis of AMR knowledge. European Journal of Public Health, 28(3), 437-439. https://doi.org/10.1093/eurpub/ckx239

Antimicrobial resistance (AMR) is a major public health threat. The UK Antibiotic Guardian (AG) behavioural change campaign developed to tackle AMR was expanded across Europe through translation into Russian, Dutch and French. Demographics and knowle... Read More about Expansion of the 'Antibiotic Guardian' one health behavioural campaign across Europe to tackle antibiotic resistance: pilot phase and analysis of AMR knowledge.

Sheep farmers’ attitudes to farm inspections and the role of sanctions and rewards as motivation to reduce the prevalence of lameness (2018)
Journal Article
Liu, N. L., Kaler, J., Ferguson, E., O’Kane, H., & Green, L. E. (2018). Sheep farmers’ attitudes to farm inspections and the role of sanctions and rewards as motivation to reduce the prevalence of lameness. Animal Welfare Journal, 27(1), https://doi.org/10.7120/09627286.27.1.067

The Welfare of Farmed Animals (England) Regulations 2007 make it an offence to allow unnecessary suffering to animals, highlighting that farmers have a duty of care for their animals. Despite this, the current global mean prevalence of lameness in sh... Read More about Sheep farmers’ attitudes to farm inspections and the role of sanctions and rewards as motivation to reduce the prevalence of lameness.

Supersolidity of lattice bosons immersed in strongly correlated Rydberg dressed atoms (2018)
Journal Article
Li, Y., Geiβler, A., Hofstetter, W., & Li, W. (2018). Supersolidity of lattice bosons immersed in strongly correlated Rydberg dressed atoms. Physical Review A, 97(2), Article 023619. https://doi.org/10.1103/PhysRevA.97.023619

Recent experiments have illustrated that long range two-body interactions can be induced by laser coupling atoms to highly excited Rydberg states. Stimulated by this achievement, we study supersolidity of lattice bosons in an experimentally relevant... Read More about Supersolidity of lattice bosons immersed in strongly correlated Rydberg dressed atoms.

Risk, networks and privateering in Liverpool during the Seven Years War, 1756-1763 (2018)
Journal Article
Haggerty, S. (2018). Risk, networks and privateering in Liverpool during the Seven Years War, 1756-1763. International Journal of Maritime History, 30(1), 30-51. https://doi.org/10.1177/0843871417745742

Privateering has often been portrayed as a particularly risky business. Some historians have posited that it was undertaken only by disreputable merchants, whilst others have argued that profits would not have been made if systems of control had been... Read More about Risk, networks and privateering in Liverpool during the Seven Years War, 1756-1763.

Firm Dynamics and Residual Inequality in Open Economies (2018)
Journal Article
Felbermayr, G., Impullitti, G., & Prat, J. (2018). Firm Dynamics and Residual Inequality in Open Economies. Journal of European Economic Association, 16(5), 1476-1539. https://doi.org/10.1093/jeea/jvx049

© The Author(s) 2018. Published by Oxford University Press on behalf of European Economic Association. All rights reserved. Wage inequality between similar workers has been on the rise in many rich countries. Recent empirical research suggests that h... Read More about Firm Dynamics and Residual Inequality in Open Economies.

Safety of antiepileptic drugs in children and young people: a prospective cohort study (2018)
Journal Article
Egunsola, O., Choonara, I., Sammons, H. M., & Whitehouse, W. P. (2018). Safety of antiepileptic drugs in children and young people: a prospective cohort study. Seizure - European Journal of Epilepsy, 56, https://doi.org/10.1016/j.seizure.2018.01.018

Purpose: This study aims to describe the incidence of adverse drug reactions (ADRs) in children receiving antiepileptic drugs (AEDs) and compare ADRs to the individual drugs when given as monotherapy. Method: Paediatric patients (≤18 years old) we... Read More about Safety of antiepileptic drugs in children and young people: a prospective cohort study.

Community based treatment for chronic oedema: an effective service model (2018)
Journal Article
Moffatt, C. J., Doherty, D., Franks, P. J., & Mortimer, P. (2018). Community based treatment for chronic oedema: an effective service model. Lymphatic Research and Biology, 16(1), 92-99. https://doi.org/10.1089/lrb.2017.0021

BACKGROUND: Chronic oedema care is patchy and of variable quality internationally. This study was undertaken to develop and evaluate a system of care that would provide for patients within a geographical area of London (Wandsworth), UK. METHODS AND... Read More about Community based treatment for chronic oedema: an effective service model.