All Outputs (4338)

Enantiopure titanocene complexes: direct evidence for paraptosis in cancer cells (2016)
Journal Article
Cini, M., Williams, H. E. L., Fay, M. W., Searle, M., Woodward, S., & Bradshaw, T. D. (2016). Enantiopure titanocene complexes: direct evidence for paraptosis in cancer cells. Metallomics, https://doi.org/10.1039/C5MT00297D

Tolerated by normal tissues, anti-cancer therapies based on titanium compounds are limited by low efficacy/selectivity and lack of understanding of their mode(s) of action. In vitro antitumour activity and mode of cell death incurred by enantiopure T... Read More about Enantiopure titanocene complexes: direct evidence for paraptosis in cancer cells.

The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review (2016)
Journal Article
Browne, A., Ahmad, S. S.-O., Beck, C. R., & Nguyen-Van-Tam, J. (in press). The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review. Journal of Travel Medicine, 23(1), https://doi.org/10.1093/jtm/tav002

BACKGROUND: Respiratory viruses spread in humans across wide geographical areas in short periods of time, resulting in high levels of morbidity and mortality. We undertook a systematic review to assess the evidence that air, ground and sea mass trans... Read More about The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review.

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168 (2016)
Journal Article
Anjum, A., Kelly, B., Aidley, J. B., Connerton, P. L., Cummings, N. J., Parkhill, J., …Bayliss, C. D. (2016). Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168. Nucleic Acids Research, https://doi.org/10.1093/nar/gkw019

Phase-variable restriction-modification systems are a feature of a diverse range of bacterial species. Stochastic, reversible switches in expression of the methyltransferase produces variation in methylation of specific sequences. Phase-variable meth... Read More about Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168.

PlanHab: the combined and separate effects of 16 days of bed rest and normobaric hypoxic confinement on circulating lipids and indices of insulin sensitivity in healthy men (2016)
Journal Article

The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger (2016)
Journal Article
Raulo, R., Archer, D. B., & Kokolski, M. (2016). The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger. AMB Express, 6(5), https://doi.org/10.1186/s13568-016-0177-0

Genes encoding the key transcription factors (TF) XlnR, ClrA and ClrB were deleted from Aspergillus niger and the resulting strains were assessed for growth on glucose and wheat straw, transcription of genes encoding glycosyl hydrolases and saccharif... Read More about The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger.

4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies (2016)
Journal Article
Cornelio, B., Laronze-Cochard, M., Ceruso, M., Ferraroni, M., Rance, G. A., Carta, F., …Sapi, J. (2016). 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. Journal of Medicinal Chemistry, 59(2), 721-732. https://doi.org/10.1021/acs.jmedchem.5b01771

Benzenesulfonamides bearing various substituted (hetero)aryl rings in the para-position were prepared by palladium nanoparticle-catalyzed Suzuki–Miyaura cross-coupling reactions and evaluated as human carbonic anhydrase (hCA, EC 4.2.1.1) inhibitors a... Read More about 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.

Generating entanglement between two-dimensional cavities in uniform acceleration (2016)
Journal Article
Regula, B., Lee, A. R., Dragan, A., & Fuentes, I. (2016). Generating entanglement between two-dimensional cavities in uniform acceleration. Physical Review D, 93(2), Article 025034. https://doi.org/10.1103/physrevd.93.025034

Moving cavities promise to be a suitable system for relativistic quantum information processing. It has been shown that an inertial and a uniformly accelerated one-dimensional cavity can become entangled by letting an atom emit an excitation while it... Read More about Generating entanglement between two-dimensional cavities in uniform acceleration.

Effect of resistive load on the performance of an organic Rankine cycle with a scroll expander (2016)
Journal Article
Zhua, J., Chen, Z., Huang, H., & Yan, Y. (2016). Effect of resistive load on the performance of an organic Rankine cycle with a scroll expander. Energy, 95, https://doi.org/10.1016/j.energy.2015.11.048

An experimental investigation is performed for an organic Rankine cycle system with different electrical resistive loads. The test rig is set up with a small scroll expander-generator unit, a boiler and a magnetically coupled pump. R134a is used as t... Read More about Effect of resistive load on the performance of an organic Rankine cycle with a scroll expander.

Insights into the transfer of silicon isotopes into the sediment record (2016)
Journal Article
Panizzo, V. N., Swann, G. E., Mackay, A., Vologina, E., Sturm, M., Pashley, V., & Horstwood, M. (2016). Insights into the transfer of silicon isotopes into the sediment record. Biogeosciences, 13(1), 147-157. https://doi.org/10.5194/bg-13-147-2016

The first δ30Si diatom data from lacustrine sediment traps are presented from Lake Baikal, Siberia. Data are compared with March surface water (upper 180 m) δ30SiDSi compositions for which a mean value of +2.28‰ ±  0.09 (95 % confidence) is derived.... Read More about Insights into the transfer of silicon isotopes into the sediment record.

Is there a EU copyright jurisprudence?: an empirical analysis of the workings of the European Court of Justice (2016)
Journal Article
Favale, M., Kretschmer, M., & Torremans, P. (2016). Is there a EU copyright jurisprudence?: an empirical analysis of the workings of the European Court of Justice. Modern Law Review, 79(1), 31-75. https://doi.org/10.1111/1468-2230.12166

The Court of Justice of the European Union (CJEU) has been suspected of carrying out a harmonising agenda over and beyond the conventional law-interpreting function of the judiciary. In relation to the development of a EU copyright law, the Court has... Read More about Is there a EU copyright jurisprudence?: an empirical analysis of the workings of the European Court of Justice.

Uses of macro social theory: a social housing case study (2016)
Journal Article
Bevan, C., & Cowan, D. (2016). Uses of macro social theory: a social housing case study. Modern Law Review, 79(1), 76-101. https://doi.org/10.1111/1468-2230.12167

This article reflects on the use of macro social theoretical perspectives to explain micro social issues. It uses social housing allocations as a case study of the issues that arise in such explanations. There has been a number of important social th... Read More about Uses of macro social theory: a social housing case study.

Simulated consultations: a sociolinguistic perspective (2016)
Journal Article
Atkins, S., Roberts, C., Hawthorne, K., & Greenhalgh, T. (2016). Simulated consultations: a sociolinguistic perspective. BMC Medical Education, 16(16), https://doi.org/10.1186/s12909-016-0535-2

Background
Assessment of consulting skills using simulated patients is widespread in medical education. Most research into such assessment is sited in a statistical paradigm that focuses on psychometric properties or replicability of such tests. Equ... Read More about Simulated consultations: a sociolinguistic perspective.

Toward integrated historical climate research: the example of atmospheric circulation reconstructions over the earth (2016)
Journal Article
Allan, R., Endfield, G., Damodaran, V., Adamson, G., Hannaford, M., Carroll, F., …Bliuc, A.-M. (2016). Toward integrated historical climate research: the example of atmospheric circulation reconstructions over the earth. Wiley Interdisciplinary Reviews: Climate Change, 7(2), 164-174. https://doi.org/10.1002/wcc.379

Climate change has become a key environmental narrative of the 21st century. However, emphasis on the science of climate change has overshadowed studies focusing on human interpretations of climate history, of adaptation and resilience, and of explor... Read More about Toward integrated historical climate research: the example of atmospheric circulation reconstructions over the earth.

Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis (2016)
Journal Article
Schoeler, T., Monk, A., Sami, M. B., Klamerus, E., Foglia, E., Brown, R., …Bhattacharyya, S. (2016). Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis. Lancet Psychiatry, 3(3), 215-225. https://doi.org/10.1016/s2215-0366%2815%2900363-6

Background: Although the link between cannabis use and development of psychosis is well established, less is known about the effect of continued versus discontinued cannabis use after the onset of psychosis. We aimed to summarise available evidence f... Read More about Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis.

Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications (2016)
Journal Article
Alvarez, M. M., Liu, J. C., Trujillo-de Santiago, G., Cha, B. H., Vishwakarma, A., Ghaemmaghami, A. M., & Khademhosseini, A. (2016). Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications. Journal of Controlled Release, 240, 349-363. https://doi.org/10.1016/j.jconrel.2016.01.026

Macrophages are key players in many physiological scenarios including tissue homeostasis. In response to injury, typically the balance between macrophage sub-populations shifts from an M1 phenotype (pro-inflammatory) to an M2 phenotype (anti-inflamma... Read More about Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications.

When the ‘unorganizable’ organize: The collective mobilization of migrant domestic workers in London (2016)
Journal Article
Jiang, Z., & Korczynski, M. (2016). When the ‘unorganizable’ organize: The collective mobilization of migrant domestic workers in London. Human Relations, 69(3), 813-838. https://doi.org/10.1177/0018726715600229

© 2016, The Author(s) 2016. The collective mobilization of migrant workers is an important issue for analysis. Three key barriers to the mobilization of migrant workers have been identified – employment conditions, which tend to prevent migrant worke... Read More about When the ‘unorganizable’ organize: The collective mobilization of migrant domestic workers in London.

Chlorophyll fluorescence parameters allow the rapid detection and differentiation of plant responses in three different wheat pathosystems (2016)
Journal Article
Ajigboye, O. O., Bousquet, L., Murchie, E. H., & Ray, R. V. (2016). Chlorophyll fluorescence parameters allow the rapid detection and differentiation of plant responses in three different wheat pathosystems. Functional Plant Biology, 43(4), 356-369. https://doi.org/10.1071/FP15280

The present study was undertaken to identify chlorophyll fluorescence (CF) parameters that can quantify changes in PSII associated with plant responses in three different wheat pathosystems of foliar, stem-base and ear diseases. The pathosystems incl... Read More about Chlorophyll fluorescence parameters allow the rapid detection and differentiation of plant responses in three different wheat pathosystems.

Numerical study of the effects of crack location on creep crack growth in weldment (2016)
Journal Article
Saber, M., Sun, W., & Hyde, T. (2016). Numerical study of the effects of crack location on creep crack growth in weldment. Engineering Fracture Mechanics, 154, https://doi.org/10.1016/j.engfracmech.2016.01.010

A numerical study on the effects of crack location on creep crack growth, in a P91 weldment, was carried out using a finite element package (ABAQUS). Models of compact tension specimens were used. The obtained results showed that, the creep crack gro... Read More about Numerical study of the effects of crack location on creep crack growth in weldment.

Adult and adolescent exposure to tobacco and alcohol content in contemporary YouTube music videos in Great Britain: a population estimate (2016)
Journal Article
Cranwell, J., Opazo-Breton, M., & Britton, J. (2016). Adult and adolescent exposure to tobacco and alcohol content in contemporary YouTube music videos in Great Britain: a population estimate. Journal of Epidemiology and Community Health, 70(5), 488-492. https://doi.org/10.1136/jech-2015-206402

Background: We estimate exposure of British adults and adolescents to tobacco and alcohol content from a sample of popular YouTube music videos.

Methods: British viewing figures were generated from 2 representative online national surveys of adult... Read More about Adult and adolescent exposure to tobacco and alcohol content in contemporary YouTube music videos in Great Britain: a population estimate.

Three dimensional ink-jet printing of biomaterials using ionic liquids and co-solvents (2016)
Journal Article
Gunasekera, D. H., Kuek, S., Hasanaj, D., He, Y., Tuck, C., Croft, A. K., & Wildman, R. D. (2016). Three dimensional ink-jet printing of biomaterials using ionic liquids and co-solvents. Faraday Discussions, 190, 509-523. https://doi.org/10.1039/C5FD00219B

1-Ethyl-3-methylimidazolium acetate ([C2C1Im][OAc]) and 1-butyl-3-methylimidazolium acetate ([C4C1Im][OAc]) have been used as solvents for the dissolution and ink-jet printing of cellulose from 1.0 to 4.8 wt%, mixed with the co-solvents 1-butanol and... Read More about Three dimensional ink-jet printing of biomaterials using ionic liquids and co-solvents.