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Sonifying the Scene: re-framing and manipulating meaning through audio augmentation (2015)
Presentation / Conference Contribution
Chamberlain, A., & Hazzard, A. (2015). Sonifying the Scene: re-framing and manipulating meaning through audio augmentation.

Digital locative music technologies are transforming the ways in which we are able to manipulate and re-frame the meaning of architecture, landscape and art. In this note we explore and outline some of the key features that are associated with this.... Read More about Sonifying the Scene: re-framing and manipulating meaning through audio augmentation.

Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils (2015)
Journal Article
Berwick, M. R., Slope, L. N., Smith, C. F., King, S. M., Newton, S. L., Gillis, R. B., …Peacock, A. F. A. (in press). Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils. Chemical Science, 7(3), https://doi.org/10.1039/c5sc04101e

Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding... Read More about Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils.

An ancestral host defence peptide within human beta-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule (2015)
Journal Article

Host defence peptides (HDPs) are critical components of innate immunity. Despite their diversity, they share common features including a structural signature, designated “γ-core motif”. We reasoned that for each HDPs evolved from an ancestral γ-core,... Read More about An ancestral host defence peptide within human beta-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule.

Russell-names: an introduction to Millian descriptivism (2015)
Journal Article
Predelli, S. (2016). Russell-names: an introduction to Millian descriptivism. Journal of Philosophical Logic, 45(5), https://doi.org/10.1007/s10992-015-9390-6

This essay studies the semantic properties of what I call Russell-names. Russell-names bear intimate semantic relations with descriptive conditions, in consonance with the main tenets of descriptivism. Yet, they are endowed with the semantic properti... Read More about Russell-names: an introduction to Millian descriptivism.

Measuring the immune system of the three-spined stickleback: investigating natural variation by quantifying immune expression in the laboratory and the wild (2015)
Journal Article
Robertson, S., Bradley, J. E., & MacColl, A. D. (2016). Measuring the immune system of the three-spined stickleback: investigating natural variation by quantifying immune expression in the laboratory and the wild. Molecular Ecology Resources, 16(3), https://doi.org/10.1111/1755-0998.12497

Current understanding of the immune system comes primarily from lab-based studies. There has been substantial interest in examining how it functions in the wild, but studies have been limited by a lack of appropriate assays and study species. The thr... Read More about Measuring the immune system of the three-spined stickleback: investigating natural variation by quantifying immune expression in the laboratory and the wild.

Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium (2015)
Journal Article
Humphreys, C. M., McLean, S., Schatschneider, S., Millat, T., Henstra, A. M., Annan, F. J., …Minton, N. P. (2015). Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium. BMC Genomics, 16(1), Article 1085. https://doi.org/10.1186/s12864-015-2287-5

© 2015 Humphreys et al. Background: Clostridium autoethanogenum is an acetogenic bacterium capable of producing high value commodity chemicals and biofuels from the C1 gases present in synthesis gas. This common industrial waste gas can act as the so... Read More about Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium.

Self-consistent solitons for vacuum decay in radiatively generated potentials (2015)
Journal Article
Garbrecht, B., & Millington, P. (2015). Self-consistent solitons for vacuum decay in radiatively generated potentials. Physical Review D, 92(12), https://doi.org/10.1103/PhysRevD.92.125022

We use a Green’s function approach in order to develop a method for calculating the tunneling rate between radiatively generated nondegenerate vacua. We apply this to a model that exhibits spontaneous symmetry breaking via the Coleman-Weinberg mechan... Read More about Self-consistent solitons for vacuum decay in radiatively generated potentials.

A correspondence of modular forms and applications to values of L-series (2015)
Journal Article
Diamantis, N., Neururer, M., & Strömberg, F. (in press). A correspondence of modular forms and applications to values of L-series. Research in Number Theory, 1(27), https://doi.org/10.1007/s40993-015-0029-z

An interpretation of the Rogers–Zudilin approach to the Boyd conjectures is established. This is based on a correspondence of modular forms which is of independent interest. We use the reinterpretation for two applications to values of L-series and v... Read More about A correspondence of modular forms and applications to values of L-series.

Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation (2015)
Journal Article
Mansor, L. S., Mehta, K., Aksentijevic, D., Carr, C. A., Lund, T., Cole, M. A., …Heather, L. C. (2016). Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation. Journal of Physiology, 594(2), 307-320. https://doi.org/10.1113/JP271242

Hypoxia activates the hypoxia-inducible factor (HIF), promoting glycolysis and suppressing mitochondrial respiration. In the type 2 diabetic heart, glycolysis is suppressed whereas fatty acid metabolism is promoted. The diabetic heart experiences chr... Read More about Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation.

Clostridium difficile-mediated effects on human intestinal epithelia: Modelling host-pathogen interactions in a vertical diffusion chamber (2015)
Journal Article
Jafari, N. V., Kuehne, S. A., Minton, N. P., Allan, E., & Bajaj-Elliott, M. (2016). Clostridium difficile-mediated effects on human intestinal epithelia: Modelling host-pathogen interactions in a vertical diffusion chamber. Anaerobe, 37, 96-102. https://doi.org/10.1016/j.anaerobe.2015.12.007

Clostridium difficile infection is one of the leading causes of healthcare associated diarrhoea in the developed world. Although the contribution of C. difficile toxins to disease pathogenesis is now well understood, many facets of host-pathogen inte... Read More about Clostridium difficile-mediated effects on human intestinal epithelia: Modelling host-pathogen interactions in a vertical diffusion chamber.

Controlling for the use of extreme weights in bank efficiency assessments during the financial crisis (2015)
Journal Article
Asmild, M., & Zhu, M. (2016). Controlling for the use of extreme weights in bank efficiency assessments during the financial crisis. European Journal of Operational Research, 251(3), 999-1015. https://doi.org/10.1016/j.ejor.2015.12.021

© 2016 We propose a method for bank efficiency assessment, based on weight restricted DEA, that limits banks’ abilities to use extreme weights, corresponding to extreme judgements of the risk adjusted prices on funding sources and assets. Based on a... Read More about Controlling for the use of extreme weights in bank efficiency assessments during the financial crisis.

Dietary mineral supplies in Malawi: spatial and socioeconomic assessment (2015)
Journal Article
Joy, E. J., Kumssa, D. B., Broadley, M. R., Watts, M. J., Young, S. D., Chilimba, A. D. C., & Ander, E. L. (2015). Dietary mineral supplies in Malawi: spatial and socioeconomic assessment. BMC Nutrition, 1, Article 42. https://doi.org/10.1186/s40795-015-0036-4

Background
Dietary mineral deficiencies are widespread globally causing a large disease burden. However, estimates of deficiency prevalence are often only available at national scales or for small population sub-groups with limited relevance for pol... Read More about Dietary mineral supplies in Malawi: spatial and socioeconomic assessment.

Structure–function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family (2015)
Journal Article
Yin, D., Urresti, S., Lafond, M., Johnston, E. M., Derikvand, F., Ciano, L., …Brumer, H. (2015). Structure–function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family. Nature Communications, 6(1), Article 10197. https://doi.org/10.1038/ncomms10197

Alcohol oxidases, including carbohydrate oxidases, have a long history of research that has generated fundamental biological understanding and biotechnological applications. Despite a long history of study, the galactose 6-oxidase/glyoxal oxidase fam... Read More about Structure–function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family.

Reinventing Westminster Abbey 1642-1660: a house of kings from revolution to restoration (2015)
Journal Article
Merritt, J. (2016). Reinventing Westminster Abbey 1642-1660: a house of kings from revolution to restoration. Journal of Ecclesiastical History, 67(1), 122-138. https://doi.org/10.1017/S0022046914002000

While historians are familiar with the destruction wrought on the nation's cathedrals during the Civil War, the rather different fate experienced by Westminster Abbey--an important symbolic building that tied together royal and religious authority--h... Read More about Reinventing Westminster Abbey 1642-1660: a house of kings from revolution to restoration.

Soot-in-oil 3D volume reconstruction through the use of electron tomography: an introductory study (2015)
Journal Article
La Rocca, A., Campbell, J., Fay, M., & Orhan, O. (2016). Soot-in-oil 3D volume reconstruction through the use of electron tomography: an introductory study. Tribology Letters, 61(1), Article 8. https://doi.org/10.1007/s11249-015-0625-z

Understanding soot nanoparticle interaction with oil additives and the causes of soot-induced thickening would assist in lubricant formulation, prolonging engine life and improving engine efficiency. Three-dimensional measurement of soot structures i... Read More about Soot-in-oil 3D volume reconstruction through the use of electron tomography: an introductory study.

Social efficiency of entry in a vertically related industry (2015)
Journal Article
Basak, D., & Mukherjee, A. (2016). Social efficiency of entry in a vertically related industry. Economics Letters, 139, https://doi.org/10.1016/j.econlet.2015.12.003

We provide a new perspective to the literature on social desirability of entry by showing that, if the input supplier has market power, social desirability of entry of the final goods producers depends on returns to scale. Entry in the final goods ma... Read More about Social efficiency of entry in a vertically related industry.

Defining the intrinsically disordered C-terminal domain of SSB reveals DNA-mediated compaction (2015)
Journal Article
Green, M., Hatter, L., Brookes, E., Soultanas, P., & Scott, D. (2016). Defining the intrinsically disordered C-terminal domain of SSB reveals DNA-mediated compaction. Journal of Molecular Biology, 428(2), 357-364. https://doi.org/10.1016/j.jmb.2015.12.007

The bacterial single-stranded DNA (ssDNA) binding protein SSB is a strictly conserved and essential protein involved in diverse functions of DNA metabolism, including replication and repair. SSB comprises a well-characterized tetrameric core of N-ter... Read More about Defining the intrinsically disordered C-terminal domain of SSB reveals DNA-mediated compaction.

Economic Evaluation of a General Hospital Unit for Older People with Delirium and Dementia (TEAM Randomised Controlled Trial) (2015)
Journal Article
Bradshaw, L. E., Tanajewski, L., Franklin, M., Gkountouras, G., Berdunov, V., Harwood, R. H., …Elliott, R. A. (2015). Economic Evaluation of a General Hospital Unit for Older People with Delirium and Dementia (TEAM Randomised Controlled Trial). PLoS ONE, 10(12), e0140662. https://doi.org/10.1371/journal.pone.0140662

Background

One in three hospital acute medical admissions is of an older person with cognitive impairment. Their outcomes are poor and the quality of their care in hospital has been criticised. A specialist unit to care for older people with delir... Read More about Economic Evaluation of a General Hospital Unit for Older People with Delirium and Dementia (TEAM Randomised Controlled Trial).

Staphylococcus aureus forms spreading dendrites that have characteristics of active motility (2015)
Journal Article
Pollitt, E. J. G., Crusz, S. A., & Diggle, S. P. (2015). Staphylococcus aureus forms spreading dendrites that have characteristics of active motility. Scientific Reports, 5(1), Article 17698. https://doi.org/10.1038/srep17698

Staphylococcus aureus is historically regarded as a non-motile organism. More recently it has been shown that S. aureus can passively move across agar surfaces in a process called spreading. We re-analysed spreading motility using a modified assay an... Read More about Staphylococcus aureus forms spreading dendrites that have characteristics of active motility.