Skip to main content

Research Repository

Advanced Search

All Outputs (516)

Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris (2011)
Journal Article
Whyteside, G., Alcocer, M. J., Kumita, J. R., Dobson, C. M., Lazarou, M., Pleass, R. J., & Archer, D. B. (2011). Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris. PLoS ONE, 6(7), Article e22692. https://doi.org/10.1371/journal.pone.0022692

We have investigated the relationship between the stability and secreted yield of a series of mutational variants of human lysozyme (HuL) in Pichia pastoris. We show that genes directly involved in the unfolded protein response (UPR), ER-associated d... Read More about Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris.

Personality is of central concern to understand health: towards a theoretical model for health psychology (2011)
Journal Article
Eamonn, F. (2013). Personality is of central concern to understand health: towards a theoretical model for health psychology. Health Psychology Review, 7(Suppl1), S32-S70. https://doi.org/10.1080/17437199.2010.547985

This paper sets out the case that personality traits are central to health psychology. To achieve this, three aims need to be addressed. First, it is necessary to show that personality influences a broad range of health outcomes and mechanisms. Secon... Read More about Personality is of central concern to understand health: towards a theoretical model for health psychology.

Modelling electricity consumption in office buildings: an agent based approach (2011)
Journal Article
Zhang, T., Siebers, P.-O., & Aickelin, U. (2011). Modelling electricity consumption in office buildings: an agent based approach. Energy and Buildings, 43(10), https://doi.org/10.1016/j.enbuild.2011.07.007

In this paper, we develop an agent-based model which integrates four important elements, i.e. organisational energy management policies/regulations, energy management technologies, electric appliances and equipment, and human behaviour, to simulate t... Read More about Modelling electricity consumption in office buildings: an agent based approach.

Real-time fermions for baryogenesis simulations (2011)
Journal Article
Saffin, P. M., & Tranberg, A. (2011). Real-time fermions for baryogenesis simulations. Journal of High Energy Physics, 2011(7), https://doi.org/10.1007/JHEP07%282011%29066

We study how to numerically simulate quantum fermions out of thermal equilibrium, in the context of electroweak baryogenesis. We find that by combining the lattice implementation of Aarts and Smit [1] with the "low cost" fermions of Borsanyi and Hind... Read More about Real-time fermions for baryogenesis simulations.

Widefield ultrastable heterodyne interferometry using a custom CMOS modulated light camera (2011)
Presentation / Conference Contribution
Patel, R., Clark, M., & Achamfuo-Yeboah, S. Widefield ultrastable heterodyne interferometry using a custom CMOS modulated light camera. Presented at Applied Industrial Optics: Spectroscopy, Imaging and Metrology 2011

A method of detecting optical heterodyne interference fringes using a custom CMOS modulated light camera array has been developed. Widefield phase images are generated using quadrature demodulation and are kept stable using a feedback system.
© 2011... Read More about Widefield ultrastable heterodyne interferometry using a custom CMOS modulated light camera.

CHOTs optical transducers (2011)
Journal Article
Arca, A., Aylott, J., Marques, L., Clark, M., Somekh, M., Smith, R., Sharples, S., Stratoudaki, T., & Chen, X. (2011). CHOTs optical transducers. Nondestructive Testing and Evaluation, 26(3-4), 353-366. https://doi.org/10.1080/10589759.2011.573555

Laser ultrasonics conventionally use direct absorption in the sample to generate ultrasound and monitor the sample to detect the ultrasound. However, in some circumstances there are significant advantages to using an optical transducer - a device to... Read More about CHOTs optical transducers.

International trends in HRM in the public sector: Reform attempts in the Republic of Georgia (2011)
Journal Article
Common, R. (2011). International trends in HRM in the public sector: Reform attempts in the Republic of Georgia. International Journal of Public Sector Management, 24(5), 421-434. https://doi.org/10.1108/09513551111147150

Purpose
The overall purpose of this paper is to explore the limits of HRM in public sector organisations, within the context of international public management. The cultural basis of HRM, derived chiefly from North America and Western Europe continu... Read More about International trends in HRM in the public sector: Reform attempts in the Republic of Georgia.

Implementing Consumer Choice Long-term Care: The Impact of Individual Budgets on Social Care Providers England (2011)
Journal Article
Wilberforce, M., Glendinning, C., Challis, D., Fernandez, J. L., Jacobs, S., Jones, K., Knapp, M., Manthorpe, J., Moran, N., Netten, A., & Stevens, M. (2011). Implementing Consumer Choice Long-term Care: The Impact of Individual Budgets on Social Care Providers England. Social Policy and Administration, 45(5), 593-612. https://doi.org/10.1111/j.1467-9515.2011.00788.x

common with many advanced welfare states, England has increasingly relied on consumerist principles to deliver both greater quality and improved efficiency the long-term care system. The Individual Budget (IB) pilots marked the next step this process... Read More about Implementing Consumer Choice Long-term Care: The Impact of Individual Budgets on Social Care Providers England.

The personalization of care services and the early impact on staff activity patterns (2011)
Journal Article
Jacobs, S., Abell, J., Stevens, M., Wilberforce, M., Challis, D., Manthorpe, J., Fernandez, J. L., Glendinning, C., Jones, K., Knapp, M., Moran, N., & Netten, A. (2013). The personalization of care services and the early impact on staff activity patterns. Journal of Social Work, 13(2), 141-163. https://doi.org/10.1177/1468017311410681

• Summary: This study examines the early impact on care coordinators' (care managers') work activity patterns of implementing the current personalization agenda within English local authorities. The Individual Budget (IB) pilots operated between 2005... Read More about The personalization of care services and the early impact on staff activity patterns.

Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray (2011)
Journal Article
Hook, A. L., Yang, J., Chen, X., Roberts, C. J., Mei, Y., Anderson, D. G., Langer, R., Alexander, M. R., & Davies, M. C. (2011). Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray. Soft Matter, 7, https://doi.org/10.1039/c1sm06063e

Atomic force microscopy has been applied to an acrylate polymer microarray to achieve a full topographic characterisation. This process discovered a small number of hydro-responsive materials created from monomers with disparate hydrophilicities that... Read More about Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray.

Tinnitus referral pathways within the National Health Service in England: a survey of their perceived effectiveness among audiology staff (2011)
Journal Article
Gander, P. E., Hoare, D. J., Collins, L. C., Smith, S., & Hall, D. A. (2011). Tinnitus referral pathways within the National Health Service in England: a survey of their perceived effectiveness among audiology staff. BMC Health Services Research, 11(162), https://doi.org/10.1186/1472-6963-11-162

Background: In the UK, audiology services deliver the majority of tinnitus patient care, but not all patients experience the same level of service. In 2009, the Department of Health released a Good Practice Guide to inform commissioners about key asp... Read More about Tinnitus referral pathways within the National Health Service in England: a survey of their perceived effectiveness among audiology staff.

The auxin signalling network translates dynamic input into robust patterning at the shoot apex (2011)
Journal Article
Vernoux, T., Brunoud, G., Farcot, E., Morin, V., Van Den Daele, H., Legrand, J., Oliva, M., Das, P., Larrieu, A., Wells, D., Guédon, Y., Armitage, L., Picard, F., Guyomarc'H, S., Cellier, C., Parry, G., Koumproglou, R., Doonan, J. H., Estelle, M., Godin, C., …Traas, J. (2011). The auxin signalling network translates dynamic input into robust patterning at the shoot apex. Molecular Systems Biology, 7(1), Article 508. https://doi.org/10.1038/msb.2011.39

The plant hormone auxin is thought to provide positional information for patterning during development. It is still unclear, however, precisely how auxin is distributed across tissues and how the hormone is sensed in space and time. The control of ge... Read More about The auxin signalling network translates dynamic input into robust patterning at the shoot apex.

Personalizing the theme park: psychometric profiling and physiological monitoring (2011)
Book Chapter
Rennick-Egglestone, S., Whitbrook, A., Leygue, C., Greensmith, J., Walker, B., Benford, S., Schnädelbach, H., Reeves, S., Marshall, J., Kirk, D., Tennent, P., Irune, A., & Rowland, D. (2011). Personalizing the theme park: psychometric profiling and physiological monitoring. In J. A. Konstan, R. Conejo, J. L. Marzo, & N. Oliver (Eds.), User modeling, adaption, and personalization: 19th international conference, UMAP 2011, Girona, Spain, July 11-15, 2011: proceedings. Springer. https://doi.org/10.1007/978-3-642-22362-4_24

Theme parks are important and complex forms of entertainment, with a broad user-base, and with a substantial economic impact. In this paper, we present a case study of an existing theme park, and use this to motivate two research challenges in relati... Read More about Personalizing the theme park: psychometric profiling and physiological monitoring.

Molecular dynamics simulations using graphics processing units (2011)
Journal Article
Baker, J., & Hirst, J. (2011). Molecular dynamics simulations using graphics processing units. Molecular Informatics, 30(6-7), https://doi.org/10.1002/minf.201100042

It is increasingly easy to develop software that exploits Graphics Processing Units (GPUs). The molecular dynamics simulation community has embraced this recent opportunity. Herein, we outline the current approaches that exploit this technology. In t... Read More about Molecular dynamics simulations using graphics processing units.

Revealing the genetic structure of a trait by sequencing a population under selection (2011)
Journal Article
Parts, L., Cubillos, F. A., Warringer, J., Jain, K., Salinas, F., Bumpstead, S. J., Molin, M., Zia, A., Simpson, J. T., Quail, M. A., Moses, A., Louis, E. J., Durbin, R., & Liti, G. (2011). Revealing the genetic structure of a trait by sequencing a population under selection. Genome Research, 21(7), https://doi.org/10.1101/gr.116731.110

One approach to understanding the genetic basis of traits is to study their pattern of inheritance among offspring of phenotypically different parents. Previously, such analysis has been limited by low mapping resolution, high labor costs, and large... Read More about Revealing the genetic structure of a trait by sequencing a population under selection.

Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate (2011)
Journal Article
Liddle, E. B., Hollis, C., Batty, M. J., Groom, M. J., Totman, J. J., Liotti, M., Scerif, G., & Liddle, P. F. (2011). Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate. Journal of Child Psychology and Psychiatry, 52(7), 761-771. https://doi.org/10.1111/j.1469-7610.2010.02333.x

Background: Deficits characteristic of Attention Deficit/Hyperactivity Disorder (ADHD), including poor attention and inhibitory control, are at least partially alleviated by factors that increase engagement of attention, suggesting a hypodopaminergic... Read More about Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate.