All Outputs (480)

Scalable reinforcement learning through hierarchical decompositions for weakly-coupled problems (2011)
Conference Proceeding

Reinforcement Learning, or Reward-Dependent Learning, has been very successful at describing how animals and humans adjust their actions so as to increase their gains and reduce their losses in a wide variety of tasks. Empirical studies have furtherm... Read More about Scalable reinforcement learning through hierarchical decompositions for weakly-coupled problems.

Correlation of central and peripheral corneal thickness in healthy corneas (2011)
Journal Article
Fares, U., Otri, A. M., Al-Aqaba, M. A., & Dua, H. S. (2012). Correlation of central and peripheral corneal thickness in healthy corneas. Contact Lens and Anterior Eye, 35(1), 39-45. https://doi.org/10.1016/j.clae.2011.07.004

Purpose To study the thickness profile of the normal cornea in order to establish any correlation between central and peripheral points. Methods Sixty-seven eyes of 40 patients were subjected to central corneal thickness measurement (CCT) with a... Read More about Correlation of central and peripheral corneal thickness in healthy corneas.

Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome (2011)
Journal Article
Stöger, R., Genereux, D. P., Hagerman, R. J., Hagerman, P. J., Tassone, F., & Laird, C. D. (2011). Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome. PLoS ONE, 6(8), Article e23648. https://doi.org/10.1371/journal.pone.0023648

Variability among individuals in the severity of fragile X syndrome (FXS) is influenced by epigenetic methylation mosaicism, which may also be common in other complex disorders. The epigenetic signal of dense promoter DNA methylation is usually assoc... Read More about Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome.

What factors influence smoking prevalence and smoke free policy enactment across the European Union Member States (2011)
Journal Article
Bogdanovica, I., McNeill, A., Murray, R., & Britton, J. (2011). What factors influence smoking prevalence and smoke free policy enactment across the European Union Member States. PLoS ONE, 6(8), Article e23889. https://doi.org/10.1371/journal.pone.0023889

Background Smoking prevention should be a primary public health priority for all governments, and effective preventive policies have been identified for decades. The heterogeneity of smoking prevalence between European Union (EU) Member States the... Read More about What factors influence smoking prevalence and smoke free policy enactment across the European Union Member States.

Active control of series connected, voltage driven power devices using a single gate drive (2011)
Conference Proceeding

A novel approach for controlling series strings of voltage driven devices (e.g. JFET, MOSFET, IGBT) is presented that allows high voltage switches to be constructed from lower voltage devices. The approach allows controlled voltage sharing under stea... Read More about Active control of series connected, voltage driven power devices using a single gate drive.

Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors (2011)
Journal Article
Baker, J. G., Adams, L. A., Salchow, K., Mistry, S. N., Middleton, R. J., Hill, S. J., & Kellam, B. (2011). Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors. Journal of Medicinal Chemistry, 54(19), 6874-6887. https://doi.org/10.1021/jm2008562

The growing practice of exploiting noninvasive fluorescence-based techniques to study G protein-coupled receptor pharmacology at the single cell and single molecule level demands the availability of high-quality fluorescent ligands. To this end, this... Read More about Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors.

The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization (2011)
Journal Article

Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucida... Read More about The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.

Can human amblyopia be treated in adulthood? (2011)
Journal Article
Astle, A. T., McGraw, P. V., & Webb, B. S. (in press). Can human amblyopia be treated in adulthood?. Strabismus, 19(3), https://doi.org/10.3109/09273972.2011.600420

Amblyopia is a common visual disorder that results in a spatial acuity deficit in the affected eye. Orthodox treatment is to occlude the unaffected eye for lengthy periods, largely determined by the severity of the visual deficit at diagnosis. Althou... Read More about Can human amblyopia be treated in adulthood?.

Drawing to learn in science (2011)
Journal Article
Ainsworth, S. E., Prain, V., & Tytler, R. (2011). Drawing to learn in science. Science, 333(6046), https://doi.org/10.1126/science.1204153

Carbon nanotube/titanium dioxide (CNT/TiO2) core-shell nanocomposites with tailored shell thickness, CNT content and photocatalytic/photoelectrocatalytic properties (2011)
Journal Article

Combining carbon nanotubes (CNTs) with TiO2 at the nano-scale level can promote the separation of the electron-hole charges generated upon irradiation. However, charge separation capability depends on the quality of the interfacial contact between CN... Read More about Carbon nanotube/titanium dioxide (CNT/TiO2) core-shell nanocomposites with tailored shell thickness, CNT content and photocatalytic/photoelectrocatalytic properties.

A technology selection framework for integrating manufacturing within a supply chain (2011)
Journal Article
Farooq, S., & O’Brien, C. (2012). A technology selection framework for integrating manufacturing within a supply chain. International Journal of Production Research, 50(11), https://doi.org/10.1080/00207543.2011.588265

This paper describes a structured analytical approach for selecting a manufacturing technology. A framework consisting of six integrated steps is proposed by considering the growing importance of supply chains in manufacturing organisations. The fram... Read More about A technology selection framework for integrating manufacturing within a supply chain.

Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS): Study protocol for a randomised controlled trial (2011)
Journal Article

Background Many older people presenting to Acute Medical Units (AMU) are discharged after only a short stay (< 72 hours), yet many re-present to hospital or die within 1 year. Comprehensive Geriatric Assessment may improve patient outcomes for this... Read More about Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS): Study protocol for a randomised controlled trial.

Variation in surgical resection for lung cancer in relation to survival: Population-based study in England 2004-2006 (2011)
Journal Article

Background: Compared with some European countries, England has low lung cancer survival and low use of surgical resection for lung cancer. The use of surgical resection varies within England. We assessed the relationship between surgical resection ra... Read More about Variation in surgical resection for lung cancer in relation to survival: Population-based study in England 2004-2006.

Ergonomically sound (2011)
Other

Medical devices are used by a multiplicity of users and in a variety of environments. Manufacturers of these devices will therefore need to be aware of differences in skills, needs, abilities and preferences among users, as well as the requirements t... Read More about Ergonomically sound.

Maize grain and soil surveys reveal suboptimal dietary selenium intake is widespread in Malawi (2011)
Journal Article
Chilimba, A. D. C., Young, S. D., Black, C. R., Rogerson, K. B., Ander, E. L., Watts, M. J., …Broadley, M. R. (2011). Maize grain and soil surveys reveal suboptimal dietary selenium intake is widespread in Malawi. Scientific Reports, 1(72), https://doi.org/10.1038/srep00072

Selenium is an essential element in human diets but the risk of suboptimal intake increases where food choices are narrow. Here we show that suboptimal dietary intake (i.e. 20–30 mg Se person21 d21) is widespread in Malawi, based on a spatial integra... Read More about Maize grain and soil surveys reveal suboptimal dietary selenium intake is widespread in Malawi.

Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin (2011)
Journal Article
Hooton, S. P., Atterbury, R. J., & Connerton, I. F. (2011). Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin. International Journal of Food Microbiology, 151(2), https://doi.org/10.1016/j.ijfoodmicro.2011.08.015

Multidrug-resistant Salmonella Typhimurium U288 is a significant pathogen of pigs, accounting for over half of all outbreaks on UK pig production premises. The potential of this serovar, and other salmonellae, to enter the food chain during the slaug... Read More about Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin.

Influence of Combined Biotic and Abiotic Stress on Nutritional Quality Parameters in Tomato (Solanum lycopersicum) (2011)
Journal Article

Induction of abiotic stress in tomato plants has been proposed as a mechanism for improving the nutritional quality of fruits. However, the occurrence of biotic stress can interfere with normal abiotic stress responses. In this study, the combined ef... Read More about Influence of Combined Biotic and Abiotic Stress on Nutritional Quality Parameters in Tomato (Solanum lycopersicum).

Developing a model for online support group use, empowering processes and psychosocial outcomes for individuals living with HIV/AIDS (2011)
Journal Article

This study examined the mechanism through which online support group (OSG) participation may promote patient empowerment among 340 individuals living with HIV/AIDS. Results from structural equation modelling revealed that greater use of OSGs was asso... Read More about Developing a model for online support group use, empowering processes and psychosocial outcomes for individuals living with HIV/AIDS.

Servicing the super-rich: new financial elites and the rise of the private wealth management retail ecology (2011)
Journal Article
Beaverstock, J. V., Hall, S., & Wainwright, T. (2011). Servicing the super-rich: new financial elites and the rise of the private wealth management retail ecology. Regional Studies, 47(6), https://doi.org/10.1080/00343404.2011.587795

The ways in which individuals' everyday lives have become increasingly tied into the international financial system has become a widely studied dimension of research on financialization. However, the ways in which financial elites consume financial s... Read More about Servicing the super-rich: new financial elites and the rise of the private wealth management retail ecology.

A song and dance: Branded entertainment and mobile promotion (2011)
Journal Article
Grainge, P. (2012). A song and dance: Branded entertainment and mobile promotion. International Journal of Cultural Studies, 15(2), 165-180. https://doi.org/10.1177/1367877911416887

This article considers the rise of branded entertainment within the contemporary marketing and media environment. Specifically, it examines how mobile phone marketing in the UK has sought to engage consumers and perform the social use of mobile techn... Read More about A song and dance: Branded entertainment and mobile promotion.