All Outputs (236)

Reclaiming Academia from Post-academia (2008)
Journal Article
Moriarty, P. (2008). Reclaiming Academia from Post-academia. Nature Nanotechnology, 3,

Post-academic science, driven as it is by commercialisation and market forces, is fundamentally at odds with core academic principles. Publicly-funded academics have an obligation to carry out science for the public good, a responsibility which is in... Read More about Reclaiming Academia from Post-academia.

Enhancing productivity: the role of management practices (2008)
Journal Article
Siebers, P.-O., Aickelin, U., Battisti, G., Celia, H., Clegg, C., Fu, X., …Peixoto, A. (2008). Enhancing productivity: the role of management practices

There is no doubt that management practices are linked to the productivity and performance of a company. However, research findings are mixed. This paper provides a multi-disciplinary review of the current evidence of such a relationship and offers s... Read More about Enhancing productivity: the role of management practices.

A model for fresh produce shelf-space allocation and inventory management with freshness-condition-dependent demand (2008)
Journal Article
Bai, R., & Kendall, G. (in press). A model for fresh produce shelf-space allocation and inventory management with freshness-condition-dependent demand. INFORMS Journal on Computing, 20(1), https://doi.org/10.1287/ijoc.1070.0219

Asignificant amount of work has investigated inventory control problems associated with fresh produce. Much of this work has considered deteriorating inventory control with many models having been proposed for various situations. However, no research... Read More about A model for fresh produce shelf-space allocation and inventory management with freshness-condition-dependent demand.

A mixer design for the pigtail braid (2008)
Journal Article
Binder, B. J., & Cox, S. M. (2008). A mixer design for the pigtail braid. Fluid Dynamics Research, 40(1), 34-44. https://doi.org/10.1016/j.fluiddyn.2006.09.001

The stirring of a body of viscous fluid using multiple stirring rods is known to be particularly effective when the rods trace out a path corresponding to a nontrivial mathematical braid. The optimal braid is the so-called "pigtail braid", in which t... Read More about A mixer design for the pigtail braid.

Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach (2008)
Journal Article
Crossley, N. A., Sena, E. S., Goehler, J., Horn, J., van der Worp, H. B., Bath, P. M., …Dirnagl, U. (2008). Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach. Stroke, 39, https://doi.org/10.1161/STROKEAHA.107.498725

Background and Purpose: At least part of the failure in the transition from experimental to clinical studies in stroke has been attributed to the imprecision introduced by problems in the design of experimental stroke studies. Using a metaepidemiolog... Read More about Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach.

Effects of dietary polyphenols on gene expression in human vascular endothelial cells (2008)
Journal Article

Previous studies have shown that consumption of fruit and vegetables plays a role in preventing the onset of CVD. These beneficial effects have been linked to the presence of polyphenolic compounds in plant-derived foods and their antioxidant capacit... Read More about Effects of dietary polyphenols on gene expression in human vascular endothelial cells.

How Cold Is Cold Dark Matter? Small-Scales Constraints from the Flux Power Spectrum of the High-Redshift Lyman-α Forest (2008)
Journal Article

No resonant tunneling in standard scalar quantum field theory (2008)
Journal Article
Copeland, E. J., Padilla, A., & Saffin, P. M. (2008). No resonant tunneling in standard scalar quantum field theory. Journal of High Energy Physics, 2008(1), https://doi.org/10.1088/1126-6708/2008/01/066

We investigate the nature of resonant tunneling in Quantum Field Theory. Following the pioneering work of Banks, Bender and Wu, we describe quantum field theory in terms of infinite dimensional quantum mechanics and utilize the ``Most probable escape... Read More about No resonant tunneling in standard scalar quantum field theory.

Direct and indirect contacts between cattle farms in north-west England (2008)
Journal Article
Brennan, M. L., Kemp, R., & Christley, R. M. (in press). Direct and indirect contacts between cattle farms in north-west England. Preventive Veterinary Medicine, 84(3/4), https://doi.org/10.1016/j.prevetmed.2007.12.009

Little is known regarding the types and frequencies of contact that exist between farms and which of these may act as pathogen transmission routes; however it is likely that farms demonstrate considerable heterogeneity in such contacts. In this cross... Read More about Direct and indirect contacts between cattle farms in north-west England.

Telomeric 3′-overhang length is associated with the size of telomeres (2008)
Journal Article
Rahman, R., Forsyth, N. R., & Cui, W. (2008). Telomeric 3′-overhang length is associated with the size of telomeres. Experimental Gerontology, 43(4), 258-265. https://doi.org/10.1016/j.exger.2008.01.005

Telomeres are specialized DNA/protein complexes that cap eukaryotic chromosome ends as T-loop structures and maintain genomic integrity. Vertebrate telomeric DNA consists of tandem double-strand repeats which terminate in a 3 0 single-strand G-rich o... Read More about Telomeric 3′-overhang length is associated with the size of telomeres.

Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic (2008)
Journal Article

The increasing resistance of human pathogens to conventional antibiotics presents a growing threat to the chemotherapeutic management of infectious diseases. The lanthionine antibiotics, still unused as therapeutic agents, have recently attracted sig... Read More about Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic.

Panel discussion [of paper: Thyroid disrupting chemicals: mechanisms and mixtures] (2008)
Journal Article

This is a panel discussion (pages 222-223) of Kevin M. Crofton's paper Thyroid disrupting chemicals: mechanisms and mixtures. Summary of main paper: Environmental contaminants are known to act as thyroid disrupting chemicals (TDCs). Broadly def... Read More about Panel discussion [of paper: Thyroid disrupting chemicals: mechanisms and mixtures].

Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease (2008)
Journal Article

Hepatitis C virus (HCV) causes acute and chronic liver diseases in humans. Its two envelope glycoproteins, E1 and E2, provide a target for host immune recognition. HCV genotypes are classified into six genetic groups. To study the role of anti-HCV E1... Read More about Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease.

Acceptability of blood and blood substitutes (2008)
Journal Article

Alternatives to donor blood have been developed in part to meet increasing demand. However, new biotechnologies are often associated with increased perceptions of risk and low acceptance. This paper reviews developments of alternatives and presents d... Read More about Acceptability of blood and blood substitutes.

Antibodies that identify only the active conformation of G(i) family G protein alpha subunits (2008)
Journal Article
Lane, J. R., Henderson, D., Powney, B., Wise, A., Rees, S., Daniels, D., …Milligan, G. (2008). Antibodies that identify only the active conformation of G(i) family G protein alpha subunits. FASEB Journal, 22(6), 1924-1932. https://doi.org/10.1096/fj.07-100388

Production of antisera able to recognize individual heterotrimeric G protein alpha subunits resulted in rapid expansion of information on their distribution and function. However, no antibodies that specifically recognize the active state have been a... Read More about Antibodies that identify only the active conformation of G(i) family G protein alpha subunits.

Stroke outcome in clinical trial patients deriving from different countries (2008)
Journal Article
Ali, M., Atula, S., Bath, P. M., Grotta, J., Hacke, W., Lyden, P. D., …Lees, K. R. (2008). Stroke outcome in clinical trial patients deriving from different countries. Stroke, 40(1), https://doi.org/10.1161/STROKEAHA.108.518035

Background and Purpose—Stroke incidence and outcome vary widely within and across geographical locations. We examined whether differences in index stroke severity, stroke risk factors, mortality, and stroke outcome across geographical locations rem... Read More about Stroke outcome in clinical trial patients deriving from different countries.

p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein (2008)
Journal Article
Brown, C., Kowalczyk, A. M., Taylor, E. R., Morgan, I. M., & Gaston, K. (2008). p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein. Virology Journal, 5, Article 5. https://doi.org/10.1186/1743-422X-5-5

Background. Human papillomavirus (HPV) DNA replication can be inhibited by the cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits viral replication and the role that this might play in the HPV life cycle are not... Read More about p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein.

Effectiveness of memory rehabilitation after stroke (2008)
Journal Article
das Nair, R., & Lincoln, N. (2008). Effectiveness of memory rehabilitation after stroke. Stroke, 39(2), https://doi.org/10.1161/STROKEAHA.107.496935

Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos (2008)
Journal Article

The oocyte is remarkable in its ability to remodel parental genomes following fertilization and to reprogram somatic nuclei after nuclear transfer (NT). To characterize the patterns of histone H4 acetylation and DNA methylation during development of... Read More about Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos.

Panel discussion [of paper: Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat] (2008)
Journal Article

This is a panel discussion of: Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat / S. Christiansen, M. Scholze, M. Axelstad, J. Boberg, A. Kortenkamp, U. Hass. Summary of main paper: The incidence... Read More about Panel discussion [of paper: Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat].