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All Outputs (233)

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes (2007)
Journal Article
Brown, R. J., Tarr, A. W., McClure, C. P., Juttla, V. S., Tagiuri, N., Irving, W. L., & Ball, J. K. (2007). Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes. Journal of General Virology, 88(2), 458-469. https://doi.org/10.1099/vir.0.82357-0

Investigation of the mechanisms underlying hepatitis C virus (HCV) envelope glycoprotein gene evolution will greatly assist rational development of broadly neutralizing antibody-based vaccines or vaccine components. Previously, comprehensive cross-ge... Read More about Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes.

Patients’ expectations of ‘first-contact care’ consultations with nurse and general practitioners in primary care (2007)
Journal Article
Redsell, S., Jackson, C., Stokes, T., Hastings, A., & Baker, R. (2007). Patients’ expectations of ‘first-contact care’ consultations with nurse and general practitioners in primary care. Quality in Primary Care, 15(1),

Background Patients’ attending UK primary care
currently receive first-contact care services from
nurses as well as general practitioners (GPs). Although
randomised trials have reported higher
satisfaction following nurse consultations,the relati... Read More about Patients’ expectations of ‘first-contact care’ consultations with nurse and general practitioners in primary care.

Exotic dynamics in a firing rate model of neural tissue with threshold accommodation (2007)
Journal Article
Coombes, S., & Owen, M. R. (2007). Exotic dynamics in a firing rate model of neural tissue with threshold accommodation. https://doi.org/10.1090/conm/440/08480

Many of the equations describing the dynamics of neural systems are written in terms of firing rate functions, which themselves are often taken to be threshold functions of synaptic activity. Dating back to work by Hill in 1936 it has been recognize... Read More about Exotic dynamics in a firing rate model of neural tissue with threshold accommodation.

Images of Childhood in Mothers' Accounts of Contemporary Childrearing (2007)
Journal Article
Murphy, E. (2007). Images of Childhood in Mothers' Accounts of Contemporary Childrearing. Childhood, 14 (1)(1),

This article examines how a sample of first-time mothers in the UK constitute childhood in general, and their own children in particular, in and through their talk about the mundane practices of child-care. The data analysed are drawn from a longitu... Read More about Images of Childhood in Mothers' Accounts of Contemporary Childrearing.

Introgression mapping in the grasses (2007)
Journal Article
King, J., Armstead, I. P., Donnison, I. S., Harper, J. A., Roberts, L. A., Thomas, H., …King, I. P. (2007). Introgression mapping in the grasses. Chromosome Research, 15(1), 105-113. https://doi.org/10.1007/s10577-006-1103-0

The unique properties of Lolium/Festuca hybrids and their derivatives provide an ideal system for intergeneric introgression. At IGER a focus on the Lolium perenne/Festuca pratensis system is being exploited to elucidate genome organization in the gr... Read More about Introgression mapping in the grasses.

Building oscillations bottom up: Elemental time scales of intracellular calcium dynamics (2007)
Book Chapter
Thul, R., & Falcke, M. (2007). Building oscillations bottom up: Elemental time scales of intracellular calcium dynamics. In L. Schimansky-Geier, B. Fiedler, J. Kurths, & E. Schöll (Eds.), Analysis and control of complex nonlinear processes in physics, chemistry and biology (293-324). World Scientific. https://doi.org/10.1142/9789812706911_0011

We analyze the elemental time scale of intracellular calcium dynamics. It is determined by the time course of Ca2+ puffs, which represent the fundamental quantum of Ca2+ release from intracellular storage compartments. Since Ca2+ puffs are truly rand... Read More about Building oscillations bottom up: Elemental time scales of intracellular calcium dynamics.

Enabling rapid and cost-effective creation of massive pervasive games in very unstable environments (2007)
Presentation / Conference Contribution
Wietrzyk, B., & Radenkovic, M. Enabling rapid and cost-effective creation of massive pervasive games in very unstable environments. Presented at 2007 Fourth Annual Conference on Wireless on Demand Network Systems and Services

Pervasive gaming is a new form of multimedia entertainment that extends the traditional computer gaming experience out into the real world. Through a combination of personal devices, positioning systems and other sensors, combined with wireless netwo... Read More about Enabling rapid and cost-effective creation of massive pervasive games in very unstable environments.

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg (2007)
Journal Article
Thomas, K. S., Cox, N. H., Savelyich, B. S., Shipley, D., Meredith, S., Nunn, A., Williams, H. C., & Reynolds, N. (2007). Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg. Trials, 8(3),

Background: This paper describes the results of a feasibility study for a randomised controlled trial (RCT).

Methods: Twenty-nine members of the UK Dermatology Clinical Trials Network (UK DCTN) expressed an interest in recruiting for this study.... Read More about Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg.

Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters (2007)
Journal Article
Schuhler, S., Warner, A., Finney, N., Bennett, G. W., Ebling, F. J., & Brameld, J. M. (2007). Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters. Journal of Neuroendocrinology, 19(4), 239-249. https://doi.org/10.1111/j.1365-2826.2006.01524.x

Thyrotrophin-releasing hormone (TRH) is known to play an important role in the control of food intake and energy metabolism in addition to its actions on the pituitary-thyroid axis. We have previously shown that central administration of TRH decrease... Read More about Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters.

The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses (2007)
Journal Article
Furmonaviciene, R., Ghaemmaghami, A. M., Boyd, S. E., Jones, N. S., Bailey, K., Willis, A. C., …Shakib, F. (2007). The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses. Clinical and Experimental Allergy, 37(2), 231-242. https://doi.org/10.1111/j.1365-2222.2007.02651.x

Background: The cysteine protease Der p 1 from the house dust mite Dermatophagoides pteronyssinus is one of the most potent allergens known. An attractive mechanism for a component of Der p 1 allergenicity lies in its ability to cleave key regulatory... Read More about The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses.

Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district (2007)
Journal Article
Hall, S. (2007). Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district. Geoforum, 38(4), 710-719. https://doi.org/10.1016/j.geoforum.2006.11.023

This paper argues that the conflicts of interest cases brought against Wall Street investment banks in the early 2000s were neither geographically nor institutionally isolated events. Rather, by combining recent work on financial knowledges in both e... Read More about Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district.

Cross-Species Identification of Mendel's I Locus (2007)
Journal Article
Armstead, I., Donnison, I., Aubry, S., Harper, J., Hortensteiner, S., James, C., …King, I. (2007). Cross-Species Identification of Mendel's I Locus. Science, 315(5808), 73-73. https://doi.org/10.1126/science.1132912

A key gene involved in plant senescence, mutations of which partially disable chlorophyll catabolism and confer stay-green leaf and cotyledon phenotypes, has been identified in Pisum sativum, Arabidopsis thaliana, and Festuca pratensis by using class... Read More about Cross-Species Identification of Mendel's I Locus.

Oscillons and quasi-breathers in D+1 dimensions (2007)
Journal Article
Saffin, P. M., & Tranberg, A. (2007). Oscillons and quasi-breathers in D+1 dimensions. Journal of High Energy Physics, 2007(1), https://doi.org/10.1088/1126-6708/2007/01/030

We study oscillons in D+1 space-time dimensions using a spherically symmetric ansatz. From Gaussian initial conditions, these evolve by emitting radiation, approaching quasi-breathers'', near-periodic solutions to the equations of motion. Using a tru... Read More about Oscillons and quasi-breathers in D+1 dimensions.

Depression and mood changes (2007)
Book Chapter
Cullum, S., Tucker, S., & Dening, T. R. (2007). Depression and mood changes. In M. Rees, & L. Keith (Eds.), Medical Problems in Women over 70: When Normative Treatment Plans do not Apply (77-92). Taylor & Francis

Depression is the most common mental health problem experienced by older women. Although everyone may feel sad or lonely at times, depressive illness in later life is qualitatively and quantitatively different. True depression is a serious and disabl... Read More about Depression and mood changes.

Foster Fathers: their experiences and contributions to fostering (2007)
Journal Article
Wilson, K., Fyson, R., & Newstone, S. (2007). Foster Fathers: their experiences and contributions to fostering

The paper reports some of the findings of an exploratory study which looks at foster fathers’ experiences of fostering and discusses their routes into foster care and their perspectives on their roles and tasks. The study collected quantitative and q... Read More about Foster Fathers: their experiences and contributions to fostering.

Risk, human rights and the management of a serious sex offender (2007)
Journal Article
Whitty, N. (2007). Risk, human rights and the management of a serious sex offender. Zeitschrift für Rechtssoziologie, 28(2), 265-276. https://doi.org/10.1515/zfrs-2007-0214

Risk and human rights discourses have become dominant features of the UK criminal justice arena. However, there has been little critical scrutiny of the ways in which these discourses relate to each other. In this article, I focus on different accoun... Read More about Risk, human rights and the management of a serious sex offender.

Robust recognition of planar shapes under affine transforms using principal component analysis (2007)
Journal Article
Tzimiropoulos, G., Mitianoudis, N., & Stathaki, T. (2007). Robust recognition of planar shapes under affine transforms using principal component analysis. IEEE Signal Processing Letters, 14(10), https://doi.org/10.1109/LSP.2007.896434

A scheme, based on Principal Component Analysis (PCA), is proposed that can be used for the recognition of 2D planar shapes under affine transformations. A PCA step is first used to map the object boundary to its canonical form, reducing the problem... Read More about Robust recognition of planar shapes under affine transforms using principal component analysis.

An affine invariant function using PCA bases with an application to within-class object recognition (2007)
Presentation / Conference Contribution
Tzimiropoulos, G., Mitianoudis, N., & Stathaki, T. (2007). An affine invariant function using PCA bases with an application to within-class object recognition.

The problem of shape-based recognition of objects under affine transformations is considered. We focus on the construction of a robust and highly discriminative affine invariant function that can be used for within-class object recognition applicatio... Read More about An affine invariant function using PCA bases with an application to within-class object recognition.

Calcium oscillations (2007)
Book Chapter
Thul, R., Bellamy, T., Roderick, L., Bootman, M., & Coombes, S. (2007). Calcium oscillations. In M. Maroto, & N. Monk (Eds.), Cellular Oscillatory Mechanisms. Springer

Changes in cellular calcium concentration control a wide range of physiological processes, from the subsecond release of synaptic neurotransmitters, to the regulation of gene expression over months or years. Calcium can also trigger cell death throu... Read More about Calcium oscillations.