Research Repository

See what's under the surface


Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics (2007)
Journal Article
Sánchez, I. E., Dellarole, M., Gaston, K., & de Prat Gay, G. (2008). Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics. Nucleic Acids Research, 36(3), 756-69. doi:10.1093/nar/gkm1104

Mucosal human papillomaviruses (HPVs) are etiological agents of oral, anal and genital cancer. Properties of high- and low-risk HPV types cannot be reduced to discrete molecular traits. The E2 protein regulates viral replication and transcription thr... Read More

The fermion spectrum in braneworld collisions (2007)
Journal Article
Saffin, P. M., & Tranberg, A. (2007). The fermion spectrum in braneworld collisions. Journal of High Energy Physics, 2007(12), doi:10.1088/1126-6708/2007/12/053

In braneworld collisions fermions originally localised on one brane can be transferred to another brane, or to a space-time boundary. By modelling branes as scalar field kinks we bounce them off boundaries and study resulting effects according to a b... Read More

Immune system approaches to intrusion detection - a review (2007)
Journal Article
Kim, J., Bentley, P., Aickelin, U., Greensmith, J., Tedesco, G., & Twycross, J. (2007). Immune system approaches to intrusion detection - a review. Natural Computing, 6(4), 413-466

The use of artificial immune systems in intrusion detection is an appealing concept for two reasons. Firstly, the human immune system provides the human body with a high level of protection from invading pathogens, in a robust, self-organised and dis... Read More

Nuclear weapons and intergenerational exploitation (2007)
Journal Article
Rendall, M. (2007). Nuclear weapons and intergenerational exploitation. Security Studies, 16(4), doi:10.1080/09636410701741070

Nuclear weapons’ defenders claim that they lower the risk of war, at the price of devastation if war breaks out. But sooner or later, on a realist analysis, catastrophic nuclear war is almost sure to come. Nuclear deterrence thus buys us a better cha... Read More

Ontogeny and nutritional programming of mitochondrial proteins in the ovine kidney, liver and lung (2007)
Journal Article
Yakubu, D., Mostyn, A., Hyatt, M., Kurlak, L., Budge, H., Stephenson, T., & Symonds, M. E. (2007). Ontogeny and nutritional programming of mitochondrial proteins in the ovine kidney, liver and lung. Reproduction, 134, doi:10.1530/REP-07-0155

This study investigated the developmental and nutritional programming of two important mitochondrial proteins, namely voltage dependent anion channel (VDAC) and cytochrome c in the sheep kidney, liver and lung. The effect of maternal nutrient restric... Read More

Cosmology with twisted tori (2007)
Journal Article
Karthauser, J. L., Saffin, P., & Hindmarsh, M. (2007). Cosmology with twisted tori. Physical Review Letters, 76(10), doi:10.1103/PhysRevD.76.104039

We consider the cosmological role of the scalar fields generated by the compactification of 11-dimensional Einstein gravity on a 7D elliptic twisted torus, which has the attractive features of giving rise to a positive semi-definite potential, and pa... Read More

Singular manifolds, topology change and the dynamics of compactification (2007)
Journal Article
Butcher, N. A., & Saffin, P. M. (2007). Singular manifolds, topology change and the dynamics of compactification. Journal of High Energy Physics, 2007(11), doi:10.1088/1126-6708/2007/11/062

We investigate the dynamics of the geometric transitions associated to compactified spacetimes. By including the dynamics of gravity we are able to follow the evolution of collapsing cycles as they attempt to undergo a topology changing transition. R... Read More

In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents (2007)
Journal Article
Stepek, G., Lowe, A. E., Buttle, D. J., Duce, I. R., & Behnke, J. M. (2007). In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents. Journal of Helminthology, 81(4), doi:10.1017/S0022149X0786408X

Infections with gastrointestinal (GI) nematodes are amongst the most prevalent worldwide, especially in tropical climates. Control of these infections is primarily through treatment with anthelmintic drugs, but the rapid development of resistance to... Read More

Can open access repositories and peer-reviewed journals coexist? (2007)
Journal Article
Pinfield, S. (2007). Can open access repositories and peer-reviewed journals coexist?. Serials, 20(3),

It is often assumed that open access repositories and peer-reviewed journals are in competition with each other and therefore will in the long term be unable to coexist. This paper takes a critical look at that assumption. It draws on the available e... Read More

Bumps and rings in a two-dimensional neural field: splitting and rotational instabilities (2007)
Journal Article
Owen, M. R., Laing, C., & Coombes, S. (2007). Bumps and rings in a two-dimensional neural field: splitting and rotational instabilities. New Journal of Physics, 9(378), doi:10.1088/1367-2630/9/10/378

In this paper we consider instabilities of localised solutions in planar neural field firing rate models of Wilson-Cowan or Amari type. Importantly we show that angular perturbations can destabilise spatially localised solutions. For a scalar model... Read More

What Pedro could do (2007)
Book
Woodard, C. (2007). What Pedro could do. University of Nottingham

This paper discusses Bernard Williams's famous case of Jim and the Indians. It contrasts two ways of diagnosing the alleged errors of Act Utilitarianism in considering this case. One approach suggests that Act Utilitarianism fails to appreciate the i... Read More

Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep (2007)
Journal Article
Hyatt, M., Budge, H., Walker, D., Stephenson, T., & Symonds, M. E. (2007). Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep. Endocrinology, 148(10), doi:10.1210/en.2007-0303

The liver is an important metabolic and endocrine organ in the fetus but the extent to which its hormone receptor (R) sensitivity is developmentally regulated in early life is not fully established. We, therefore, examined developmental changes in mR... Read More

Flexural Behavior of Brittle RC Members Rehabilitated with Concrete Jacketing (2007)
Journal Article
Thermou, G., Pantazopoulou, S., & Elnashai, A. (2007). Flexural Behavior of Brittle RC Members Rehabilitated with Concrete Jacketing. Journal of Structural Engineering, 133(10), 1373-1384. doi:10.1061/(asce)0733-9445(2007)133:10(1373)

The composite flexural action of prismatic reinforced concrete (RC) members repaired/strengthened by RC jacketing was modeled with a dual-section approach. The model considers the relative slip at the interface between the existing member and the jac... Read More

Should data monitoring committees assess efficacy when considering safety in trails in acute stroke? (2007)
Journal Article
Bath, P. M., Gray, L. J., & Wahlgren, N. (2007). Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?. International Journal of Clinical Practice, 61(10),

The primary role of a trials Data Monitoring Committee (DMC) is to ensure the safety of enrolled patients. In stroke trials, safety is monitored typically by comparing death and stroke specific events between treatment groups. DMCs may also have the... Read More

Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs and toxicity in the developing male Wistar(Han) rat (2007)
Journal Article
Bell, D. R., Clode, S., Fan, M., Fernandes, A., Foster, P. M. D., Jiang, T., …White, S. (2007). Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs and toxicity in the developing male Wistar(Han) rat. Toxicological Sciences, 99(2),

We compared the effects of a single acute dose, or chronic fetal exposure, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the male reproductive system of the Wistar(Han) rat. Tissue samples were taken from dams on GD16 and GD21, and from offspring... Read More