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Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets (2005)
Journal Article
Yamada, E., Montoya, M., Schuettler, C. G., Hickling, T. P., Tarr, A. W., Vitelli, A., …Borrow, P. (2005). Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets. Journal of General Virology, 86(9), 2507-2512. https://doi.org/10.1099/vir.0.81169-0

Hepatitis C virus (HCV) binding to hepatocytes is thought to be mediated via interaction of the E2 glycoprotein with (co-)receptors including CD81 and scavenger receptor class B type I (SR-BI). Here, the expression of CD81 and SR-BI was analysed on p... Read More about Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets.

Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein (2005)
Journal Article
Owsianka, A., Tarr, A. W., Juttla, V. S., Lavillette, D., Bartosch, B., Cosset, F. L., …Patel, A. H. (2005). Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. Journal of Virology, 79(17), 11095-11104. https://doi.org/10.1128/JVI.79.17.11095-11104.2005

Hepatitis C virus (HCV) remains a significant threat to the general health of the world's population, and there is a pressing need for the development of new treatments and preventative vaccines. Here, we describe the generation of retrovirus-based p... Read More about Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein.

Suitability testing of selected wastes and natural substrates for permeable reactive barriers (PRBs) (2005)
Journal Article
Wantanaphong, J., Bailey, E. H., & Mooney, S. J. (2005). Suitability testing of selected wastes and natural substrates for permeable reactive barriers (PRBs). Iahs Publication, 110-116

Performance of barrier materials is important for the long-term success of permeable reactive barriers (PRBs). A number of selected wastes and natural materials were tested in batch experiments for their ability to remove heavy metals from synthetic... Read More about Suitability testing of selected wastes and natural substrates for permeable reactive barriers (PRBs).

Quantification of the effects of pore clogging in potential PRB substrates using image analysis (2005)
Journal Article
Wantanaphong, J., Mooney, S. J., & Bailey, E. H. (2005). Quantification of the effects of pore clogging in potential PRB substrates using image analysis. Iahs Publication, 154-159

Permeable reactive barriers (PRBs) have demonstrated a promising approach for groundwater remediation. However, one concern is the deterioration of barrier material performance due to mineral precipitation and pore clogging. This study sought to quan... Read More about Quantification of the effects of pore clogging in potential PRB substrates using image analysis.

Social work and care management (2005)
Book Chapter
Challis, D., Hughes, J., & Sutcliffe, C. (2005). Social work and care management. In A. Burns, J. O'Brien, & D. Ames (Eds.), Dementia (186-190). (Third edition). CRC Press

Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP 2/EP4 receptors and SP-1 transcription factor binding sites (2005)
Journal Article
Bradbury, D., Clarke, D., Seedhouse, C., Corbettt, L., Stocks, J., & Knox, A. (2005). Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP 2/EP4 receptors and SP-1 transcription factor binding sites. Journal of Biological Chemistry, 280(34), 29993-30000. https://doi.org/10.1074/jbc.M414530200

Prostaglandin E2 (PGE2) can increase vascular endothelial growth factor A (VEGF-A) production but the mechanisms involved are unclear. Here we characterized the transcriptional mechanisms involved in human airway smooth muscle cells (HASMC). PGE2 inc... Read More about Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP 2/EP4 receptors and SP-1 transcription factor binding sites.

Hybrid Variable Neighborhood HyperHeuristicsfor Exam Timetabling Problems (2005)
Presentation / Conference Contribution
Qu, R., & Burke, E. (2005, August). Hybrid Variable Neighborhood HyperHeuristicsfor Exam Timetabling Problems. Paper presented at The Sixth Metaheuristics International Conference 2005, Vienna, Austria

This paper presents our work on analysing the high level search within a graph based hyperheuristic. The graph based hyperheuristic solves the problem at a higher level by searching through permutations of graph heuristics rather than the actual solu... Read More about Hybrid Variable Neighborhood HyperHeuristicsfor Exam Timetabling Problems.

Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin (2005)
Journal Article
Jethwa, P. H., Small, C. J., Smith, K. L., Seth, A., Darch, S. J., Abbott, C. R., …Bloom, S. R. (2005). Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin. AJP - Endocrinology and Metabolism, 289(2), E301-E305. https://doi.org/10.1152/ajpendo.00404.2004

Intracerebroventricular (ICV) administration of Neuromedin U (NMU), a hypothalamic neuropeptide, or leptin, an adipostat hormone released from adipose tissue, reduces food intake and increases energy expenditure. Leptin stimulates the release of NMU... Read More about Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin.

Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release (2005)
Journal Article
Bewick, G. A., Dhillo, W. S., Darch, S. J., Murphy, K. G., Gardiner, J. V., Jethwa, P. H., …Bloom, S. R. (2005). Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release. Endocrinology, 146(8), 3526-3534. https://doi.org/10.1210/en.2004-1659

Nociceptin or orphanin FQ (N/OFQ) and its receptor NOP1 are expressed in hypothalamic nuclei involved in energy homeostasis. N/OFQ administered by intracerebroventricular or arcuate nucleus (ARC) injection increases food intake in satiated rats. The... Read More about Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release.

Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca (2005)
Journal Article
Atterbury, R. J., Dillon, E., Swift, C., Connerton, P. L., Frost, J., Dodd, C. E., Rees, C. E., & Connerton, I. F. (2005). Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca. Applied and Environmental Microbiology, 71(8), https://doi.org/10.1128/AEM.71.8.4885-4887.2005

Campylobacter jejuni and Campylobacter-specific bacteriophage were enumerated from broiler chicken ceca selected from 90 United Kingdom flocks (n = 205). C. jejuni counts in the presence of bacteriophage (mean log10 5.1 CFU/g) were associated with a... Read More about Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca.

Autocracy in crisis: Nicholas the last (2005)
Book Chapter
Badcock, S. (2005). Autocracy in crisis: Nicholas the last. In I. Thatcher (Ed.), Late Imperial Russia : Problems and prospects (9-27). Manchester University Press

Attenuation technique for measuring sediment displacement levels (2005)
Journal Article
Munro, R. J., & Dalziel, S. B. (2005). Attenuation technique for measuring sediment displacement levels. Experiments in Fluids, 39(3), https://doi.org/10.1007/s00348-005-0998-0

A technique for obtaining accurate, high (spatial) resolution measurements of sediment redeposition levels is described. In certain regimes, the method may also be employed to provide measurements of sediment layer thickness as a function of time. Th... Read More about Attenuation technique for measuring sediment displacement levels.

Cloning: Eight years after Dolly (2005)
Journal Article
Campbell, K. H., Alberio, R., Choi, I., Fisher, P., Kelly, R. D., Lee, J. H., & Maalouf, W. (2005). Cloning: Eight years after Dolly. Reproduction in Domestic Animals, 40(4), 256-268. https://doi.org/10.1111/j.1439-0531.2005.00591.x

It is now 8 years since the birth of Dolly, the first animal produced by nuclear transfer using a donor cell population established from an adult animal. During this time, the technique of nuclear transfer has been successfully applied to a range of... Read More about Cloning: Eight years after Dolly.

Constitutive regulation of the Insl3 gene in rat Leydig cells (2005)
Journal Article
Sadeghian, H., Anand-Ivell, R., Balvers, M., Relan, V., & Ivell, R. (2005). Constitutive regulation of the Insl3 gene in rat Leydig cells. Molecular and Cellular Endocrinology, 241(1-2), 10-20. https://doi.org/10.1016/j.mce.2005.03.017

Insulin-like factor 3 (Insl3) is a major new product of the Leydig cells in all mammalian species so far examined. The rat Insl3 gene is encoded by two exons in close juxtaposition to the Jak3 gene. Using RT-PCR analysis we now show that in the rat t... Read More about Constitutive regulation of the Insl3 gene in rat Leydig cells.

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development (2005)
Journal Article
Nateri, A. S., Spencer-Dene, B., & Behrens, A. (2005). Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development. Nature, 437(7056), 281-285. https://doi.org/10.1038/nature03914

The proto-oncoprotein c-Jun is a component of the AP-1 transcription factor, the activity of which is augmented in many tumour types. An important mechanism in the stimulation of AP-1 function is amino-terminal phosphorylation of c-Jun by the c-Jun N... Read More about Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development.

Xanthine Oxidase Activity in Vitro:  Effects of Food Extracts and Components (2005)
Journal Article
Dew, T. P., Day, A. J., & Morgan, M. R. A. (2005). Xanthine Oxidase Activity in Vitro:  Effects of Food Extracts and Components. Journal of Agricultural and Food Chemistry, 53(16), 6510-6515. https://doi.org/10.1021/jf050716j

There is significant interest in the direct antioxidant activities of dietary polyphenols, due to associations between consumption of polyphenol-rich foods, such as fruits and vegetables, and decreased incidence of oxidative-stress related disease. H... Read More about Xanthine Oxidase Activity in Vitro:  Effects of Food Extracts and Components.

The geochemistry of fluids from an active shallow submarine hydrothermal system: Milos island, Hellenic Volcanic Arc (2005)
Journal Article
Valsami-Jones, E., Baltatzis, E., Bailey, E. H., Boyce, A. J., Alexander, J. L., Magganas, A., …Ragnarsdottir, K. V. (2005). The geochemistry of fluids from an active shallow submarine hydrothermal system: Milos island, Hellenic Volcanic Arc. Journal of Volcanology and Geothermal Research, 148(1-2), 130-151. https://doi.org/10.1016/j.jvolgeores.2005.03.018

Geothermal activity in the Aegean island of Milos (Greece), associated with island-arc volcanism, is abundant both on-and off-shore. Hydrothermal fluids venting from several sites, mainly shallow submarine (up to 10 m), but also just above seawater l... Read More about The geochemistry of fluids from an active shallow submarine hydrothermal system: Milos island, Hellenic Volcanic Arc.