All Outputs (19)

Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation (2023)
Working Paper

Background Sulfasalazine induced cytopenia, nephrotoxicity, and hepatotoxicity is uncommon during long-term treatment. Some guidelines recommend three monthly monitoring blood-tests indefinitely while others recommend stopping monitoring after one ye... Read More about Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation.

Exposure to Climate Change Information on Affect and Pro‐Environmental Behavioural Intentions: A Randomised Controlled Trial (2023)
Working Paper

The study aimed to investigate the effect of climate change exposure on affect and pro-environmental behavioural intentions in a randomised controlled trial. An online survey was completed by 100 adult participants and included measures of affect and... Read More about Exposure to Climate Change Information on Affect and Pro‐Environmental Behavioural Intentions: A Randomised Controlled Trial.

Origins of polysaccharide conformation and viscoelasticity in miscible heterogeneous solvent (2023)
Working Paper

MPeat2D - A fully coupled mechanical-ecohydrological model of peatland development in two dimensions (2023)
Working Paper

Higher dimensional models of peatland development are required to analyse the influence of spatial heterogeneity and complex feedback mechanisms. However, the current models exclude the mechanical process that leads to uncertainties in simulating the... Read More about MPeat2D - A fully coupled mechanical-ecohydrological model of peatland development in two dimensions.

A time-resolved Förster resonance energy transfer assay to investigate inhibitor binding to ABCG2 (2023)
Working Paper

The human ATP-binding cassette (ABC) transporter, ABCG2 is responsible for multidrug resistance in some tumours. Detailed knowledge of its activity is crucial for understanding drug transport and resistance in cancer, and has implications for wider p... Read More about A time-resolved Förster resonance energy transfer assay to investigate inhibitor binding to ABCG2.

Understanding public perceptions of virtual reality psychological therapy: development of the attitudes towards virtual reality therapy (AVRT) Scale (Preprint) (2023)
Working Paper

Accelerated elastin degradation by age-disease interaction: a common feature in age-related diseases (2023)
Working Paper

Aging is a major driving force for many diseases but the relationship between age, aging processes and age-related diseases is not fully understood. Fragmentation and loss of ultra-long-lived elastin are key features in aging and several age-related... Read More about Accelerated elastin degradation by age-disease interaction: a common feature in age-related diseases.

Progress in lignocellulosic biomass valorization for biofuels and value‐added chemical production in the EU: A focus on thermochemical conversion processes (2023)
Working Paper

The demand for sustainable energy sources has increased owing to environmental concerns, such as climate change, rising energy demand and rapid industrialization. Biomass utilization for bioenergy and value‐added chemical production has become essent... Read More about Progress in lignocellulosic biomass valorization for biofuels and value‐added chemical production in the EU: A focus on thermochemical conversion processes.

Beyond the Bedside: Protocol for a scoping review exploring the experiences of non-practicing healthcare professionals within health professions education (2023)
Working Paper

Background: The number of healthcare professionals leaving clinical practice and transitioning to alternative careers in health professions education is increasing. Among these non-practicing healthcare professionals, concerns have been reported rega... Read More about Beyond the Bedside: Protocol for a scoping review exploring the experiences of non-practicing healthcare professionals within health professions education.

A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data (2023)
Working Paper

MicrobeMASST, a taxonomically-informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 microbial monocultures, users can search known... Read More about A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data.

Examining the Use of Autonomous Systems for Home Health Support using a Smart Mirror (2023)
Working Paper

The home is becoming a key location for healthcare delivery, including the use of technology driven by autonomous systems (AS) to monitor and support healthcare plans. Using the example of a smart mirror, this paper describes the outcomes of focus gr... Read More about Examining the Use of Autonomous Systems for Home Health Support using a Smart Mirror.

PDI-functionalised glass beads: efficient, metal-free heterogeneous photocatalysts suitable for flow photochemistry (2023)
Working Paper

Perylene diimides (PDI) have an extraordinary ability to activate both energy and electron transfer process upon light excitation, however, their extremely low solubility has hindered their wide use as photocatalysts. Here, we show a series of suppor... Read More about PDI-functionalised glass beads: efficient, metal-free heterogeneous photocatalysts suitable for flow photochemistry.

UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI) (2023)
Working Paper

The scale of the current outbreak of highly pathogenic avian influenza (HPAI) due to the A/H5N1 virus in the United Kingdom is unprecedented. In addition to its economic impact on the commercial poultry sector, the disease has devastated wild bird co... Read More about UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI).

Generative AI: Implications and Applications for Education (2023)
Working Paper

The launch of ChatGPT in November 2022 precipitated a panic among some educators while prompting qualified enthusiasm from others. Under the umbrella term Generative AI, ChatGPT is an example of a range of technologies for the delivery of computer-ge... Read More about Generative AI: Implications and Applications for Education.

Comparative Judgement Modeling to Map Forced Marriage at Local Levels (2023)
Working Paper

Forcing someone into marriage against their will is a violation of their human rights. In 2021, the county of Nottinghamshire, UK, launched a strategy to tackle forced marriage and violence against women and girls. However, accessing information abou... Read More about Comparative Judgement Modeling to Map Forced Marriage at Local Levels.

Early-Universe Model Building (2023)
Working Paper

Theoretical investigations into the evolution of the early universe are an essential part of particle physics that allow us to identify viable extensions to the Standard Model as well as motivated parameter space that can be probed by various experim... Read More about Early-Universe Model Building.

Differences between online trial participants who have used statutory mental health services and who have not: analysis of baseline data from two pragmatic trials of a digital health intervention (2023)
Working Paper

Background: Digital health interventions have become an established part of mental health service provision internationally. Regulators have positioned the best-practice standard of evidence as an interventional study with a comparator reflective of... Read More about Differences between online trial participants who have used statutory mental health services and who have not: analysis of baseline data from two pragmatic trials of a digital health intervention.

Pathways for the Valorization of Animal and Human Waste to Biofuels, Sustainable Materials and Value-Added Chemicals (2023)
Working Paper

Human and animal waste, including waste products originating from human or animal digestive systems such as urine, feces, and animal manure, have constituted a nuisance to the environment. Inappropriate disposal and poor sanitation of human and anima... Read More about Pathways for the Valorization of Animal and Human Waste to Biofuels, Sustainable Materials and Value-Added Chemicals.

Sustainability of Bioenergy – Mapping the Risks & Benefits to Inform Future Bioenergy Systems (2023)
Working Paper

Bioenergy is widely included in energy strategies for its GHG mitigation potential. Bioenergy technologies will likely have to be deployed at scale to meet decarbonisation targets, and consequently biomass will have to be increasingly grown/mobilised... Read More about Sustainability of Bioenergy – Mapping the Risks & Benefits to Inform Future Bioenergy Systems.