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Characteristics of positive feedback provided by UK health service users: content analysis of examples from two databases (2024)
Journal Article
Lloyd, R., Slade, M., Byng, R., Russell, A., Ng, F., Stirzaker, A., & Rennick-Egglestone, S. (2024). Characteristics of positive feedback provided by UK health service users: content analysis of examples from two databases. BMJ Health & Care Informatics, 31(1), Article e101113. https://doi.org/10.1136/bmjhci-2024-101113

Background Most feedback received by health services is positive. Our systematic scoping review mapped all available empirical evidence for how positive patient feedback creates healthcare change. Most included papers did not provide specific details... Read More about Characteristics of positive feedback provided by UK health service users: content analysis of examples from two databases.

Digital wound monitoring with artificial intelligence to prioritise surgcial wounds in cardiac surgery: protocol for a randomised feasibility trial (WISDOM) (2024)
Journal Article
Tanner, J., Melissa, R., Roy, H., Jacqueline, B., James, J., Lara, M., Janet, B., Sarah, B., Jon, D., Kieth, W., Luxmi, D., & Karen, C. (2024). Digital wound monitoring with artificial intelligence to prioritise surgcial wounds in cardiac surgery: protocol for a randomised feasibility trial (WISDOM). BMJ Open, 14(9), Article e086486. https://doi.org/10.1136/bmjopen-2024-086486

Introduction: Digital surgical wound monitoring for patients at home is becoming an increasingly common method of wound follow-up. This regular monitoring improves patient outcomes by detecting wound complications early and enabling treatment to star... Read More about Digital wound monitoring with artificial intelligence to prioritise surgcial wounds in cardiac surgery: protocol for a randomised feasibility trial (WISDOM).

Deep learning the intergalactic medium using lyman-alpha forest at 4 ≤ z ≤ 5 (2024)
Journal Article
Nasir, F., Gaikwad, P., Davies, F. B., Bolton, J. S., Puchwein, E., & Bosman, S. E. I. (2024). Deep learning the intergalactic medium using lyman-alpha forest at 4 ≤ z ≤ 5. Monthly Notices of the Royal Astronomical Society, 534(2), 1299–1316. https://doi.org/10.1093/mnras/stae2153

Unveiling the thermal history of the intergalactic medium (IGM) at 4 ≤z ≤5 holds the potential to reveal early onset He II reionization or lingering thermal fluctuations from H I reionization. We set out to reconstruct the IGM gas properties along si... Read More about Deep learning the intergalactic medium using lyman-alpha forest at 4 ≤ z ≤ 5.

A Qualitative Study of the Views of Ethnic Minority Healthcare Workers Towards COVID-19 Vaccine Education (CoVE) to Support Vaccine Promotion and Uptake (2024)
Journal Article
Blake, H., Premakumar, V., Premakumar, A., Fecowycz, A., Kamkosi Khulumula, S., Jones, W., & Somerset, S. (2024). A Qualitative Study of the Views of Ethnic Minority Healthcare Workers Towards COVID-19 Vaccine Education (CoVE) to Support Vaccine Promotion and Uptake. New Solutions: A Journal of Environmental and Occupational Health Policy, 34(3), 198-212. https://doi.org/10.1177/10482911241273914

Ethnic minority healthcare workers (EMHCW) are at high risk of COVID-19 infection and adverse health outcomes, but vaccine uptake is low among ethnic minority communities, including EMHCW. We explored the views of EMHCW towards COVID-19 Vaccine Educa... Read More about A Qualitative Study of the Views of Ethnic Minority Healthcare Workers Towards COVID-19 Vaccine Education (CoVE) to Support Vaccine Promotion and Uptake.

A stereodivergent multicomponent approach for the synthesis of C–N atropisomeric peptide analogues (2024)
Journal Article
Roper, N. J., Campbell, A. D. G., Waddell, P. G., Brown, A. K., Ermanis, K., & Armstrong, R. J. (2024). A stereodivergent multicomponent approach for the synthesis of C–N atropisomeric peptide analogues. Chemical Science, 15(40), 16743-16751. https://doi.org/10.1039/d4sc04700a

A four-component Ugi reaction is described for the stereoselective synthesis of novel C–N atropisomeric peptide analogues. Using this approach, a combination of simple, readily available starting materials (ortho-substituted anilines, aldehydes, carb... Read More about A stereodivergent multicomponent approach for the synthesis of C–N atropisomeric peptide analogues.

Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice (2024)
Journal Article
Morgan, H. L., Eid, N., Holmes, N., Henson, S., Wright, V., Coveney, C., Winder, C., O’Neil, D. M., Dunn, W. B., Boocock, D. J., & Watkins, A. J. (2024). Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice. BMC Biology, 22, Article 207. https://doi.org/10.1186/s12915-024-01992-0

Background: The importance of parental diet in relation to eventual offspring health is increasing in prominence due to the increased frequency of parents of reproductive age consuming poor diets. Whilst maternal health and offspring outcome have bee... Read More about Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice.

The effects of modal value and imperative mood on self-predicted compliance to health guidance: the case of COVID-19 (2024)
Journal Article
Vilar-Lluch, S., McClaughlin, E., Adolphs, S., Knight, D., & Nichele, E. (2024). The effects of modal value and imperative mood on self-predicted compliance to health guidance: the case of COVID-19. Text and Talk - An Interdisciplinary Journal of Language, Discourse and Communication Studies, https://doi.org/10.1515/text-2023-0125

Health messaging is effective if it is to achieve audience adherence to guidance. Through the lens of Systemic Functional Linguistics, we examine the expression of obligation in poster-based health campaigns (4 posters) employed during the COVID-19 p... Read More about The effects of modal value and imperative mood on self-predicted compliance to health guidance: the case of COVID-19.

Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial (2024)
Journal Article
Sheehan, L., Woodward, A., Adamson, J., Archer, M., Drummond, A., Hewison, A., Jordan, C., Keding, A., Kottam, L., Madan, I., Martland, M., McDaid, C., McDonald, D. A., Parkinson, G., Reed, M., Sinclair, L., Smith, T. O., Thomson, L., Watkins, L., Wu, Q., & Baker, P. (2024). Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial. BMJ Open, 14(9), Article e085962. https://doi.org/10.1136/bmjopen-2024-085962

Background: In the UK, one in four patients are in work at the time of their hip or knee replacement surgery. These patients receive little support about their return to work (RTW). There is a need for an occupational support intervention that encour... Read More about Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial.

John Stuart Mill, Socialism, Pluralism and Competition (2024)
Journal Article
MCCABE, H. (in press). John Stuart Mill, Socialism, Pluralism and Competition. British Journal for the History of Philosophy,

Most work on John Stuart Mill focuses on his account of liberty, but as Bruce Baum rightly argues, Mill’s commitment to “the free development of individuality” applied in the economic sphere as well as the political. Mill was a socialist, and as part... Read More about John Stuart Mill, Socialism, Pluralism and Competition.

Enhanced 4-hydroxybutyrate incorporation into the PHA terpolymer of Haloferax mediterranei by heterologous expression of 4-hydroxybutyrate-CoA transferases/synthetases (2024)
Journal Article
Zheng, X., Chacón, M., Allers, T., Dixon, N., & Winterburn, J. (2024). Enhanced 4-hydroxybutyrate incorporation into the PHA terpolymer of Haloferax mediterranei by heterologous expression of 4-hydroxybutyrate-CoA transferases/synthetases. Biochemical Engineering Journal, 212, Article 109498. https://doi.org/10.1016/j.bej.2024.109498

The polyhydroxyalkanoate terpolymer, P[(3HB)-co-(3HV)-co-(4HB)], is a promising plastic alternative for specialized applications, notably in medical and pharmaceutical sectors. Haloferax mediterranei (Hfx), an extreme halophile arch... Read More about Enhanced 4-hydroxybutyrate incorporation into the PHA terpolymer of Haloferax mediterranei by heterologous expression of 4-hydroxybutyrate-CoA transferases/synthetases.

The Earth, Brain, Health Commission: how to preserve mental health in a changing environment (2024)
Journal Article
Schumann, G., Barciela, R., Benegal, V., Bernard, A., Desrivieres, S., Feng, J., Gong, P., Heinz, A., Hunt, X., Jin, L., Luterbacher, J., Marquand, A., Meyer-Lindenberg, A., Salomon, J., Schwalber, A., Shetty, S., Stahl, B., & Thompson, P. (2024). The Earth, Brain, Health Commission: how to preserve mental health in a changing environment. nature mental health, 2, 1121–1123. https://doi.org/10.1038/s44220-024-00314-1

Diatom silicon isotope ratios in Quaternary research: Where do we stand? (2024)
Journal Article
Frings, P. J., Panizzo, V. N., Sutton, J. N., & Ehlert, C. (2024). Diatom silicon isotope ratios in Quaternary research: Where do we stand?. Quaternary Science Reviews, 344, Article 108966. https://doi.org/10.1016/j.quascirev.2024.108966

Silicon stable isotope ratios (expressed as δ30Si) in biogenic silica have been widely used as a proxy for past and present biogeochemical cycling in both marine and lacustrine settings, in particular for nutrient utilization reconstructions. Yet an... Read More about Diatom silicon isotope ratios in Quaternary research: Where do we stand?.

Perceived negativity in British general election communications (2024)
Journal Article
Milazzo, C., & Ryan, J. B. (2024). Perceived negativity in British general election communications. Electoral Studies, 92, Article 102863. https://doi.org/10.1016/j.electstud.2024.102863

British parties – and their candidates – frequently engage in the use of negative messaging. While previous studies shed light on the frequency and source of such messages, we know less about how negative messages are received. In this research note,... Read More about Perceived negativity in British general election communications.

Structuring white rice with gellan gum reduces the glycemic response in healthy humans (2024)
Journal Article
Alshammari, N. A., Riches, K., Muttakin, S., Hoad, C. L., Strkalj, L., Gouseti, O., Bakalis, S., Lovegrove, A., Spiller, R. C., Gowland, P. A., Aithal, G. P., Yakubov, G. E., Taylor, M. A., & Marciani, L. (2024). Structuring white rice with gellan gum reduces the glycemic response in healthy humans. Food Research International, 196, Article 115090. https://doi.org/10.1016/j.foodres.2024.115090

White rice has a high glycemic index and its consumption has been linked to an increased risk of developing type-2 diabetes mellitus, increased diabetes associated complications and obesity. In recent in vitro studies we have shown that addition of f... Read More about Structuring white rice with gellan gum reduces the glycemic response in healthy humans.

Comparative judgement modeling to map forced marriage at local levels (2024)
Journal Article
Seymour, R., Nyarko-Agyei, A., Mccabe, H., Severn, K., Sirl, D., Kypraios, T., & Taylor, A. (in press). Comparative judgement modeling to map forced marriage at local levels. Annals of Applied Statistics,

Forcing someone into marriage against their will is a violation of their human rights. In 2021, the county of Nottinghamshire, UK, launched a strategy to tackle forced marriage and violence against women and girls. We set out to map the risk of force... Read More about Comparative judgement modeling to map forced marriage at local levels.

A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter (2024)
Journal Article
Ding, Q., Cai, J., Jin, L., Hu, W., Song, W., Rose, P., Tang, Z., Zhan, Y., Bao, L., Lei, W., & Zhu, Y. Z. (2024). A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter. MedComm, 5(10), Article e711. https://doi.org/10.1002/mco2.711

SMYD3 (SET and MYND domain-containing 3) is a histone lysine methyltransferase highly expressed in different types of cancer(s) and is a promising epigenetic target for developing novel antitumor therapeutics. No selective inhibitors for this protein... Read More about A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter.

Short-term risk of cardiovascular events in people newly diagnosed with gout (2024)
Journal Article
Cipolletta, E., Nakafero, G., Richette, P., Avery, A. J., Mamas, M. A., Tata, L. J., & Abhishek, A. (2024). Short-term risk of cardiovascular events in people newly diagnosed with gout. Arthritis and Rheumatology, https://doi.org/10.1002/art.42986

Objectives
To investigate the temporal association between first diagnosis of gout and cardiovascular events in the short-term.

Methods
We performed a self-controlled case series analysis and a cohort study using data from linked primary care, h... Read More about Short-term risk of cardiovascular events in people newly diagnosed with gout.