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Rank-based model selection for multiple ions quantum tomography (2012)
Journal Article
Guţă, M., Kypraios, T., & Dryden, I. (2012). Rank-based model selection for multiple ions quantum tomography. New Journal of Physics, 14(105002), https://doi.org/10.1088/1367-2630/14/10/105002

The statistical analysis of measurement data has become a key component of many quantum engineering experiments. As standard full state tomography becomes unfeasible for large dimensional quantum systems, one needs to exploit prior information and th... Read More about Rank-based model selection for multiple ions quantum tomography.

A randomised trial of primary tamoxifen versus mastectomy plus adjuvant tamoxifen in fit elderly women with invasive breast carcinoma of high oestrogen receptor content: long-term results at 20 years of follow-up (2012)
Journal Article

Background Long-term analysis of a randomised trial in Nottingham comparing tamoxifen versus surgery as initial treatment demonstrated that in oestrogen receptor (ER)-unselected cases, surgery achieved better local control, with no difference in ove... Read More about A randomised trial of primary tamoxifen versus mastectomy plus adjuvant tamoxifen in fit elderly women with invasive breast carcinoma of high oestrogen receptor content: long-term results at 20 years of follow-up.

A new model and a hyper-heuristic approach for two-dimensional shelf space allocation (2012)
Journal Article
Bai, R., Van Woensel, T., Kendall, G., & Burke, E. K. (in press). A new model and a hyper-heuristic approach for two-dimensional shelf space allocation. 4OR: A Quarterly Journal of Operations Research, 11(1), https://doi.org/10.1007/s10288-012-0211-2

In this paper, we propose a two-dimensional shelf space allocation model. The second dimension stems from the height of the shelf. This results in an integer nonlinear programming model with a complex form of objective function. We propose a multiple... Read More about A new model and a hyper-heuristic approach for two-dimensional shelf space allocation.

The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article
Tarlinton, R., Daly, J. M., Dunham, S. P., & Kydd, J. M. (2012). The challenge of Schmallenberg virus emergence in Europe. Veterinary Journal, 194(1), 10-18. https://doi.org/10.1016/j.tvjl.2012.08.017

The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in technology and collaboration between veterinary... Read More about The challenge of Schmallenberg virus emergence in Europe.

Cost effectiveness of epidural steroid injections to manage chronic lower back pain (2012)
Journal Article
Whynes, D. K., McCahon, R. A., Ravenscroft, A., & Hardman, J. (2012). Cost effectiveness of epidural steroid injections to manage chronic lower back pain. BMC Anesthesiology, 12(26), Article 26. https://doi.org/10.1186/1471-2253-12-26

Background The efficacy of epidural steroid injections in the management of chronic low back pain is disputed, yet the technique remains popular amongst physicians and patients alike. This study assesses the cost effectiveness of injections administ... Read More about Cost effectiveness of epidural steroid injections to manage chronic lower back pain.

Reliability of quantitative echocardiography in adult sheep and goats (2012)
Journal Article
Hallowell, G. D., Potter, T. J., & Bowen, I. M. (2012). Reliability of quantitative echocardiography in adult sheep and goats. BMC Veterinary Research, 8(Septem), Article 11. https://doi.org/10.1186/1746-6148-8-181

Background Echocardiography is a non-invasive method for assessment of the ovine and caprine heart. Complete reference ranges for cardiac dimensions and time indices for both species are not currently available and reliability of these measurements... Read More about Reliability of quantitative echocardiography in adult sheep and goats.

Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in acute Myeloid Leukaemia (2012)
Journal Article

Background The CD34+CD38- subset of AML cells is enriched for resistance to current chemotherapeutic agents and considered to contribute to disease progression and relapse in Acute Myeloid Leukaemia (AML) patients following initial treatment. Met... Read More about Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in acute Myeloid Leukaemia.

Perceptual learning reconfigures the effects of visual adaptation (2012)
Journal Article
McGovern, D. P., Roach, N. W., & Webb, B. S. (2012). Perceptual learning reconfigures the effects of visual adaptation. Journal of Neuroscience, 32(39), https://doi.org/10.1523/JNEUROSCI.1363-12.2012

Our sensory experiences over a range of different timescales shape our perception of the environment. Two particularly striking short-term forms of plasticity with manifestly different time courses and perceptual consequences are those caused by visu... Read More about Perceptual learning reconfigures the effects of visual adaptation.

Cognitive control over motor output in Tourette syndrome (2012)
Journal Article
Jung, J., Jackson, S. R., Parkinson, A., & Jackson, G. M. (2013). Cognitive control over motor output in Tourette syndrome. Neuroscience and Biobehavioral Reviews, 37(6), https://doi.org/10.1016/j.neubiorev.2012.08.009

Tourette syndrome [TS] is a neurodevelopmental disorder characterised by chronic vocal and motor tics. TS has been associated with dysfunctional cognitive (inhibitory) control of behaviour, however the evidence for this, beyond the occurrence of tics... Read More about Cognitive control over motor output in Tourette syndrome.

WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma (2012)
Journal Article
Rogers, H., Sousa, S., Salto, C., Arenas, E., Coyle, B., & Grundy, R. G. (2012). WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma. British Journal of Cancer, 107, https://doi.org/10.1038/bjc.2012.377

Background: Medulloblastoma is the most common malignant childhood brain tumour. Aberrant activation of the WNT/β-catenin pathway occurs in approximately 25% of medulloblastomas. However, its role in medulloblastoma pathogenesis is not understood.... Read More about WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.

Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2 (2012)
Journal Article
Abouseada, N. M., Assafi, M. S. A., Mahdavi, J., Oldfield, N. J., Wheldon, L. M., Wooldridge, K. G., & Ala'Aldeen, D. A. (2012). Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2. PLoS ONE, 7(9), Article 10. https://doi.org/10.1371/journal.pone.0046233

Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are major bacterial agents of meningitis. They each bind the 37/67-kDa laminin receptor (LamR) via the surface protein adhesins: meningococcal PilQ and PorA, H. influenzae Om... Read More about Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2.

Why are family carers of people with dementia dissatisfied with general hospital care?: a qualitative study (2012)
Journal Article
Jurgens, F. J., Clissett, P., Gladman, J. R., & Harwood, R. H. (2012). Why are family carers of people with dementia dissatisfied with general hospital care?: a qualitative study. BMC Geriatrics, 12(57), Article 1. https://doi.org/10.1186/1471-2318-12-57

Background Families and other carers report widespread dissatisfaction with general hospital care for confused older people. Methods We undertook a qualitative interviews study of 35 family carers of 34 confused older patients to ascertain their... Read More about Why are family carers of people with dementia dissatisfied with general hospital care?: a qualitative study.

Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives (2012)
Journal Article
Freemantle, A., & Seymour, J. (2012). Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives. BMC Research Notes, 5(524), https://doi.org/10.1186/1756-0500-5-524

Background: Despite evidence suggesting that the Liverpool Care Pathway for the Dying Patient is a structured and proficient means of supporting care delivery in the last hours or days of life, discrepancies in uptake are widespread. This explorator... Read More about Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives.

A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion (2012)
Journal Article
Guttery, D. S., Poulin, B., Ferguson, D. J. P., Szöőr, B., Wickstead, B., Carroll, P. L., …Tewari, R. (2012). A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion. PLoS Pathogens, 8(9), Article e1002948. https://doi.org/10.1371/journal.ppat.1002948

Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in many eukaryotic signalling pathways, and are often deregulated in a number of pathological... Read More about A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion.

A cooperative instinct (2012)
Journal Article
Gaechter, S. (2012). A cooperative instinct. Nature, 489(7416), https://doi.org/10.1038/489374a

Acting on a gut feeling may sometimes lead to poor decisions, but it will usually support the common good, according to a study showing that human intuition favours cooperative, rather than selfish, behaviour.

Coping with and factors impacting upon the experience of lung cancer in patients and primary carers (2012)
Journal Article
Ellis, J., Lloyd-williams, M., Wagland, R., Bailey, C., & Molassiotis, A. (in press). Coping with and factors impacting upon the experience of lung cancer in patients and primary carers. European Journal of Cancer Care, 22(1), https://doi.org/10.1111/ecc.12003

There is a paucity of research exploring patients' and their informal carers' experience of coping with and factors impacting on the lung cancer experience. This study aims to explore how patients and their informal carers cope with a diagnosis of lu... Read More about Coping with and factors impacting upon the experience of lung cancer in patients and primary carers.