A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling
(2011)
Journal Article
Sher, A. A., Wang, K., Wathen, A., Maybank, P. J., Mirams, G. R., Abramson, D., …Gavaghan, D. J. (2013). A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling. Future Generation Computer Systems, 29(2), 591-598. https://doi.org/10.1016/j.future.2011.09.006
Computational cardiac models provide important insights into the underlying mechanisms of heart function. Parameter estimation in these models is an ongoing challenge with many existing models being overparameterised. Sensitivity analysis presents a... Read More about A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling.