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All Outputs (195)

Elucidating the interactions between the adhesive and transcriptioanl functions of beta-catenin in normal and cancerous cells (2007)
Journal Article
van Leeuwen, I. M. M., Byrne, H. M., Jensen, O. E., & King, J. R. (2007). Elucidating the interactions between the adhesive and transcriptioanl functions of beta-catenin in normal and cancerous cells. Journal of Theoretical Biology, 247(1), 77-102. https://doi.org/10.1016/j.jtbi.2007.01.019

Wnt signalling is involved in a wide range of physiological and pathological processes. The presence of an extracellular Wnt stimulus induces cytoplasmic stabilisation and nuclear translocation of beta-catenin, a protein that also plays an essential... Read More about Elucidating the interactions between the adhesive and transcriptioanl functions of beta-catenin in normal and cancerous cells.

Coping with food allergy: Exploring the role of the online support group (2007)
Journal Article
Coulson, N. S., & Knibb, R. C. (2007). Coping with food allergy: Exploring the role of the online support group. Cyberpsychology and Behavior, 10(1), 145-148. https://doi.org/10.1089/cpb.2006.9978

The aims of this study were to explore the reasons for participation in an online support group for individuals affected by food allergy, its perceived advantages and disadvantages as well as impact on the relationship with healthcare providers. A to... Read More about Coping with food allergy: Exploring the role of the online support group.

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes (2007)
Journal Article
Brown, R. J., Tarr, A. W., McClure, C. P., Juttla, V. S., Tagiuri, N., Irving, W. L., & Ball, J. K. (2007). Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes. Journal of General Virology, 88(2), 458-469. https://doi.org/10.1099/vir.0.82357-0

Investigation of the mechanisms underlying hepatitis C virus (HCV) envelope glycoprotein gene evolution will greatly assist rational development of broadly neutralizing antibody-based vaccines or vaccine components. Previously, comprehensive cross-ge... Read More about Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes.

Patients’ expectations of ‘first-contact care’ consultations with nurse and general practitioners in primary care (2007)
Journal Article
Redsell, S., Jackson, C., Stokes, T., Hastings, A., & Baker, R. (2007). Patients’ expectations of ‘first-contact care’ consultations with nurse and general practitioners in primary care. Quality in Primary Care, 15(1),

Background Patients’ attending UK primary care currently receive first-contact care services from nurses as well as general practitioners (GPs). Although randomised trials have reported higher satisfaction following nurse consultations,the relati... Read More about Patients’ expectations of ‘first-contact care’ consultations with nurse and general practitioners in primary care.

Exotic dynamics in a firing rate model of neural tissue with threshold accommodation (2007)
Journal Article
Coombes, S., & Owen, M. R. (2007). Exotic dynamics in a firing rate model of neural tissue with threshold accommodation

Many of the equations describing the dynamics of neural systems are written in terms of firing rate functions, which themselves are often taken to be threshold functions of synaptic activity. Dating back to work by Hill in 1936 it has been recognize... Read More about Exotic dynamics in a firing rate model of neural tissue with threshold accommodation.

Images of Childhood in Mothers' Accounts of Contemporary Childrearing (2007)
Journal Article
Murphy, E. (2007). Images of Childhood in Mothers' Accounts of Contemporary Childrearing. Childhood, 14 (1)(1),

This article examines how a sample of first-time mothers in the UK constitute childhood in general, and their own children in particular, in and through their talk about the mundane practices of child-care. The data analysed are drawn from a longitu... Read More about Images of Childhood in Mothers' Accounts of Contemporary Childrearing.

Introgression mapping in the grasses (2007)
Journal Article
King, J., Armstead, I. P., Donnison, I. S., Harper, J. A., Roberts, L. A., Thomas, H., …King, I. P. (2007). Introgression mapping in the grasses. Chromosome Research, 15(1), 105-113. https://doi.org/10.1007/s10577-006-1103-0

The unique properties of Lolium/Festuca hybrids and their derivatives provide an ideal system for intergeneric introgression. At IGER a focus on the Lolium perenne/Festuca pratensis system is being exploited to elucidate genome organization in the gr... Read More about Introgression mapping in the grasses.

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg (2007)
Journal Article
Thomas, K. S., Cox, N. H., Savelyich, B. S., Shipley, D., Meredith, S., Nunn, A., Williams, H. C., & Reynolds, N. (2007). Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg. Trials, 8(3),

Background: This paper describes the results of a feasibility study for a randomised controlled trial (RCT). Methods: Twenty-nine members of the UK Dermatology Clinical Trials Network (UK DCTN) expressed an interest in recruiting for this study.... Read More about Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg.

Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters (2007)
Journal Article
Schuhler, S., Warner, A., Finney, N., Bennett, G. W., Ebling, F. J., & Brameld, J. M. (2007). Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters. Journal of Neuroendocrinology, 19(4), 239-249. https://doi.org/10.1111/j.1365-2826.2006.01524.x

Thyrotrophin-releasing hormone (TRH) is known to play an important role in the control of food intake and energy metabolism in addition to its actions on the pituitary-thyroid axis. We have previously shown that central administration of TRH decrease... Read More about Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters.

The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses (2007)
Journal Article
Furmonaviciene, R., Ghaemmaghami, A. M., Boyd, S. E., Jones, N. S., Bailey, K., Willis, A. C., …Shakib, F. (2007). The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses. Clinical and Experimental Allergy, 37(2), 231-242. https://doi.org/10.1111/j.1365-2222.2007.02651.x

Background: The cysteine protease Der p 1 from the house dust mite Dermatophagoides pteronyssinus is one of the most potent allergens known. An attractive mechanism for a component of Der p 1 allergenicity lies in its ability to cleave key regulatory... Read More about The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses.

Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district (2007)
Journal Article
Hall, S. (2007). Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district. Geoforum, 38(4), 710-719. https://doi.org/10.1016/j.geoforum.2006.11.023

This paper argues that the conflicts of interest cases brought against Wall Street investment banks in the early 2000s were neither geographically nor institutionally isolated events. Rather, by combining recent work on financial knowledges in both e... Read More about Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district.

Cross-Species Identification of Mendel's I Locus (2007)
Journal Article
Armstead, I., Donnison, I., Aubry, S., Harper, J., Hortensteiner, S., James, C., …King, I. (2007). Cross-Species Identification of Mendel's I Locus. Science, 315(5808), 73-73. https://doi.org/10.1126/science.1132912

A key gene involved in plant senescence, mutations of which partially disable chlorophyll catabolism and confer stay-green leaf and cotyledon phenotypes, has been identified in Pisum sativum, Arabidopsis thaliana, and Festuca pratensis by using class... Read More about Cross-Species Identification of Mendel's I Locus.

Oscillons and quasi-breathers in D+1 dimensions (2007)
Journal Article
Saffin, P. M., & Tranberg, A. (2007). Oscillons and quasi-breathers in D+1 dimensions. Journal of High Energy Physics, 2007(1), https://doi.org/10.1088/1126-6708/2007/01/030

We study oscillons in D+1 space-time dimensions using a spherically symmetric ansatz. From Gaussian initial conditions, these evolve by emitting radiation, approaching ``quasi-breathers'', near-periodic solutions to the equations of motion. Using a t... Read More about Oscillons and quasi-breathers in D+1 dimensions.

Foster Fathers: their experiences and contributions to fostering (2007)
Journal Article
Wilson, K., Fyson, R., & Newstone, S. (2007). Foster Fathers: their experiences and contributions to fostering

The paper reports some of the findings of an exploratory study which looks at foster fathers’ experiences of fostering and discusses their routes into foster care and their perspectives on their roles and tasks. The study collected quantitative and q... Read More about Foster Fathers: their experiences and contributions to fostering.

Risk, human rights and the management of a serious sex offender (2007)
Journal Article
Whitty, N. (2007). Risk, human rights and the management of a serious sex offender. Zeitschrift für Rechtssoziologie, 28(2), 265-276. https://doi.org/10.1515/zfrs-2007-0214

Risk and human rights discourses have become dominant features of the UK criminal justice arena. However, there has been little critical scrutiny of the ways in which these discourses relate to each other. In this article, I focus on different accoun... Read More about Risk, human rights and the management of a serious sex offender.

Robust recognition of planar shapes under affine transforms using principal component analysis (2007)
Journal Article
Tzimiropoulos, G., Mitianoudis, N., & Stathaki, T. (2007). Robust recognition of planar shapes under affine transforms using principal component analysis. IEEE Signal Processing Letters, 14(10), https://doi.org/10.1109/LSP.2007.896434

A scheme, based on Principal Component Analysis (PCA), is proposed that can be used for the recognition of 2D planar shapes under affine transformations. A PCA step is first used to map the object boundary to its canonical form, reducing the problem... Read More about Robust recognition of planar shapes under affine transforms using principal component analysis.

Diatom oxygen isotopes: evidence of a species effect in the sediment record (2007)
Journal Article
Swann, G. E., Leng, M. J., Sloane, H. J., Maslin, M. A., & Onodera, J. (2007). Diatom oxygen isotopes: evidence of a species effect in the sediment record. Geochemistry, Geophysics, Geosystems, 8(6), Article Q06012. https://doi.org/10.1029/2006GC001535

Diatom oxygen isotope measurements are commonly made on bulk mixed species assemblages due to the difficulty in purifying and separating individual taxa. As such, it is essential to understand processes in diatoms which may lead to isotope offsets bo... Read More about Diatom oxygen isotopes: evidence of a species effect in the sediment record.

Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes (2007)
Journal Article
Stepek, G., Curtis, R., Kerry, B., Shewry, P., Clark, S., Lowe, A., …Behnke, J. (2007). Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes. Parasitology, 134(12), https://doi.org/10.1017/S0031182007003289

Cysteine proteinases from the fruit and latex of plants, such as papaya, pineapple and fig, have previously been shown to have substantial anthelmintic efficacy, in vitro and in vivo, against a range of animal parasitic nematodes. In this paper, we d... Read More about Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes.

Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333) (2007)
Journal Article
Sprigg, N., Willmot, M., Gray, L. J., Sunderland, A., Pomeroy, V., Walker, M., & Bath, P. M. (2007). Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333). Journal of Human Hypertension, 21(8),

Amphetamine enhances recovery after experimental ischaemia and has shown promise in small clinical trials when combined with motor or sensory stimulation. Amphetamine, a sympathomimetic, might have haemodynamic effects in stroke patients, although li... Read More about Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333).