All Outputs (33)

On Using Genetic Algorithm for Initialising Semi-supervised Fuzzy c-Means Clustering (2016)
Journal Article
Lai, D. T. C., & Garibaldi, J. M. (2017). On Using Genetic Algorithm for Initialising Semi-supervised Fuzzy c-Means Clustering. Advances in Intelligent Systems and Computing, 532, 3-14. https://doi.org/10.1007/978-3-319-48517-1_1

In a previous work, suitable initialisation techniques were incorporated with semi-supervised Fuzzy c-Means clustering (ssFCM) to improve clustering results on a trial and error basis. In this work, we present a single fully-automatic version of an e... Read More about On Using Genetic Algorithm for Initialising Semi-supervised Fuzzy c-Means Clustering.

A multi-cycled sequential memetic computing approach for constrained optimisation (2016)
Journal Article
Sun, J., Garibaldi, J. M., Zhang, Y., & Al-Shawabkeh, A. (2016). A multi-cycled sequential memetic computing approach for constrained optimisation. Information Sciences, 340-341, 175-190. https://doi.org/10.1016/j.ins.2016.01.003

In this paper, we propose a multi-cycled sequential memetic computing structure for constrained optimisation. The structure is composed of multiple evolutionary cycles. At each cycle, an evolutionary algorithm is considered as an operator, and connec... Read More about A multi-cycled sequential memetic computing approach for constrained optimisation.

A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations (2015)
Journal Article
Reps, J. M., Garibaldi, J. M., Aickelin, U., Gibson, J. E., & Hubbard, R. B. (2015). A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations. Journal of Biomedical Informatics, 56, https://doi.org/10.1016/j.jbi.2015.06.011

Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunately there are many complexities and underlying issues when analysing l... Read More about A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations.

From Interval-Valued Data to General Type-2 Fuzzy Sets (2014)
Journal Article
Wagner, C., Miller, S., Garibaldi, J. M., Anderson, D. T., & Havens, T. C. (2015). From Interval-Valued Data to General Type-2 Fuzzy Sets. IEEE Transactions on Fuzzy Systems, 23(2), 248-269. https://doi.org/10.1109/tfuzz.2014.2310734

In this paper, a new approach is presented to model interval-based data using fuzzy sets (FSs). Specifically, we show how both crisp and uncertain intervals (where there is uncertainty about the endpoints of intervals) collected from individual or mu... Read More about From Interval-Valued Data to General Type-2 Fuzzy Sets.

Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs (2014)
Journal Article
Reps, J., M. Garibaldi, J., Aickelin, U., Soria, D., E. Gibson, J., & B. Hubbard, R. (2014). Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs. Drug Safety, 37(3), 163-170. https://doi.org/10.1007/s40264-014-0137-z

Background: Children are frequently prescribed medication `o-label', meaning there has not been sucient testing of the medication to determine its safety or eectiveness. The main reason this safety knowledge is lacking is due to
ethical restrictions... Read More about Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs.

A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery (2013)
Journal Article
Reps, J. M., Garibaldi, J. M., Aickelin, U., Soria, D., Gibson, J. E., & Hubbard, R. B. (2014). A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery. IEEE Journal of Biomedical and Health Informatics, 18(2), 537-547. https://doi.org/10.1109/JBHI.2013.2281505

Drugs are frequently prescribed to patients with the aim of improving each patient's medical state, but an unfortunate consequence of most prescription drugs is the occurrence of undesirable side effects. Side effects that occur in more than one in a... Read More about A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery.

A methodology for automatic classification of breast cancer immunohistochemical data using semi-supervised Fuzzy c-means (2013)
Journal Article
Lai, D. T. C., Garibaldi, J. M., Soria, D., & Roadknight, C. M. (2014). A methodology for automatic classification of breast cancer immunohistochemical data using semi-supervised Fuzzy c-means. Central European Journal of Operations Research, 22(3), 475-499. https://doi.org/10.1007/s10100-013-0318-3

Previously, a semi-manual method was used to identify six novel and clinically useful classes in the Nottingham Tenovus Breast Cancer dataset. 663 out of 1,076 patients were classified. The objectives of our work is three folds. Firstly, our primary... Read More about A methodology for automatic classification of breast cancer immunohistochemical data using semi-supervised Fuzzy c-means.

A quantifier-based fuzzy classification system for breast cancer patients (2013)
Journal Article
Soria, D., Garibaldi, J. M., Green, A. R., Powe, D. G., Nolan, C. C., Lemetre, C., …Ellis, I. O. (2013). A quantifier-based fuzzy classification system for breast cancer patients. Artificial Intelligence in Medicine, 58(3), https://doi.org/10.1016/j.artmed.2013.04.006

Objectives:Recent studies of breast cancer data have identified seven distinct clinical phenotypes (groups) using immunohistochemical analysis and a range of different clustering techniques. Consensus between unsupervised classification algorithms ha... Read More about A quantifier-based fuzzy classification system for breast cancer patients.

Using rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression data (2012)
Journal Article
Glaab, E., Bacardit, J., Garibaldi, J. M., & Krasnogor, N. (2012). Using rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression data. PLoS ONE, 7(7), Article e39932. https://doi.org/10.1371/journal.pone.0039932

Microarray data analysis has been shown to provide an effective tool for studying cancer and genetic diseases. Although classical machine learning techniques have successfully been applied to find informative genes and to predict class labels for new... Read More about Using rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression data.

MysiRNA-designer: a workflow for efficient siRNA design (2011)
Journal Article
Mysara, M., Garibaldi, J. M., & ElHefnawi, M. (2011). MysiRNA-designer: a workflow for efficient siRNA design. PLoS ONE, 6(10), Article e25642. https://doi.org/10.1371/journal.pone.0025642

The design of small interfering RNA (siRNA) is a multi factorial problem that has gained the attention of many researchers in the area of therapeutic and functional genomics. MysiRNA score was previously introduced that improves the correlation of si... Read More about MysiRNA-designer: a workflow for efficient siRNA design.

A "non-parametric" version of the naive Bayes classifier (2011)
Journal Article
Soria, D., Garibaldi, J. M., Ambrogi, F., Biganzoli, E. M., & Ellis, I. O. (2011). A "non-parametric" version of the naive Bayes classifier. Knowledge-Based Systems, 24(6), https://doi.org/10.1016/j.knosys.2011.02.014

Many algorithms have been proposed for the machine learning task of classication. One of the simplest methods, the naive Bayes classifyer, has often been found to give good performance despite the fact that its underlying assumptions (of independence... Read More about A "non-parametric" version of the naive Bayes classifier.

A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients (2010)
Journal Article
Soria, D., Garibaldi, J. M., Ambrogi, F., Green, A. R., Powe, D., Rakha, E., …Ellis, I. O. (2010). A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients. Computers in Biology and Medicine, 40(3), https://doi.org/10.1016/j.compbiomed.2010.01.003

Single clustering methods have often been used to elucidate clusters in high dimensional medical data, even though reliance on a single algorithm is known to be problematic. In this paper, we present a methodology to determine a set of ‘core classes’... Read More about A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients.

Cancer profiles by Affinity Propagation (2009)
Journal Article
Soria, D., Garibaldi, J. M., Ambrogi, F., Boracchi, P., Raimondi, E., & Biganzoli, E. M. (2009). Cancer profiles by Affinity Propagation. International Journal of Knowledge Engineering and Soft Data Paradigms, 1(3), https://doi.org/10.1504/IJKESDP.2009.028814

The Affinity Propagation algorithm is applied to various problems of breast and cutaneous tumours subtyping using traditional biologic markers. The algorithm provides a procedure to determine the number of profiles to be considered. Well know breast... Read More about Cancer profiles by Affinity Propagation.