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Stromule formation is dependent upon plastid size, plastid differentiation status and the density of plastids within the cell (2004)
Journal Article
Waters, M., Fray, R., & Pyke, K. (2004). Stromule formation is dependent upon plastid size, plastid differentiation status and the density of plastids within the cell. The Plant Journal, 39(4),

Stromules are motile extensions of the plastid envelope membrane, whose roles are not fully understood. They are present on all plastid types but are more common and extensive on non-green plastids that are sparsely distributed within the cell. Durin... Read More about Stromule formation is dependent upon plastid size, plastid differentiation status and the density of plastids within the cell.

Second Language Instructors and CALL: A Multidisciplinary Research Framework (2004)
Journal Article
Zapata, G. (2004). Second Language Instructors and CALL: A Multidisciplinary Research Framework. Computer Assisted Language Learning, 17(3-4), 339-356. https://doi.org/10.1080/0958822042000319610

The increasing importance of computer assisted language learning (CALL) in second language (L2) classes has added a new dimension to L2 research, and it has challenged scholars to find valid research methods and theoretical frameworks that can be app... Read More about Second Language Instructors and CALL: A Multidisciplinary Research Framework.

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration (2004)
Journal Article
Raivich, G., Bohatschek, M., Da Costa, C., Iwata, O., Galiano, M., Hristova, M., Nateri, A. S., Makwana, M., Riera-Sans, L., Wolfer, D. P., Lipp, H. P., Aguzzi, A., Wagner, E. F., & Behrens, A. (2004). The AP-1 transcription factor c-Jun is required for efficient axonal regeneration. Neuron, 43(1), 57-67. https://doi.org/10.1016/j.neuron.2004.06.005

Nerve injury triggers numerous changes in the injured neurons and surrounding nonneuronal cells that ultimately result in successful target reinnervation or cell death. c-Jun is a component of the heterodimeric AP-1 transcription factor, and c-Jun is... Read More about The AP-1 transcription factor c-Jun is required for efficient axonal regeneration.

A pattern matching technique for measuring sediment displacement levels (2004)
Journal Article
Munro, R. J., Dalziel, S. B., & Jehan, H. (2004). A pattern matching technique for measuring sediment displacement levels. Experiments in Fluids, 37(3), https://doi.org/10.1007/s00348-004-0829-8

This paper describes a novel technique for obtaining accurate, high (spatial) resolution measurements of sediment redeposition levels. A sequence of different random patterns are projected onto a sediment layer and captured using a high-resolution ca... Read More about A pattern matching technique for measuring sediment displacement levels.

Mucosal vaccination against serogroup B meningococci: Induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin (2004)
Journal Article
Bowe, F., Lavelle, E. C., McNeela, E. A., Hale, C., Clare, S., Arico, B., Giuliani, M. M., Rae, A., Huett, A., Rappuoli, R., Dougan, G., & Mills, K. H. (2004). Mucosal vaccination against serogroup B meningococci: Induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin. Infection and Immunity, 72(7), 4052-4060. https://doi.org/10.1128/IAI.72.7.4052-4060.2004

Conjugated polysaccharide vaccines protect against serogroup C meningococci. However, this approach cannot be applied to serogroup B, which is still a major cause of meningitis. We evaluated the immunogenicity of three surface-exposed proteins from s... Read More about Mucosal vaccination against serogroup B meningococci: Induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin.

Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium (2004)
Journal Article
Wiles, S., Clare, S., Harker, J., Huett, A., Young, D., Dougan, G., & Frankel, G. (2004). Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium. Cellular Microbiology, 6(10), 963-972. https://doi.org/10.1111/j.1462-5822.2004.00414.x

Citrobacter rodentium belongs to a family of human and animal enteric pathogens that includes the clinically significant enterohaemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli (EPEC). These pathogens use attaching and effacing (A/E)... Read More about Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium.

Effects of fungicides on eyespot, caused predominantly by Oculimacula acuformis, and yield of early-drilled winter wheat (2004)
Journal Article
Ray, R. V., Jenkinson, P., & Edwards, S. G. (2004). Effects of fungicides on eyespot, caused predominantly by Oculimacula acuformis, and yield of early-drilled winter wheat. Crop Protection, 23(12), 1199-1207. https://doi.org/10.1016/j.cropro.2004.05.003

The effectiveness against eyespot of nine fungicide treatments, applied at GS 31, was evaluated in early-drilled winter wheat crops. Visual assessments of stem-base diseases were made before fungicide application and at GS 39/55 and 69/70 of cultivar... Read More about Effects of fungicides on eyespot, caused predominantly by Oculimacula acuformis, and yield of early-drilled winter wheat.

Virtual-Build-to-Order as a Mass Customization Order Fulfilment Model (2004)
Journal Article
Brabazon, P. G., & MacCarthy, B. L. (2004). Virtual-Build-to-Order as a Mass Customization Order Fulfilment Model

Virtual-build-to-order (VBTO) is a form of order fulfilment system in which the producer has the ability to search across the entire pipeline of finished stock, products in production and those in the production plan, in order to find the best produc... Read More about Virtual-Build-to-Order as a Mass Customization Order Fulfilment Model.

DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings (2004)
Journal Article
Thirlway, J., Turner, I. J., Gibson, C. T., Gardiner, L., Brady, K., Allen, S., Roberts, C. J., & Soultanas, P. (2004). DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings. Nucleic Acids Research, 32(10),

Loading of the replicative ring helicase onto the origin of replication (oriC) is the final outcome of a well coordinated series of events that collectively constitute a primosomal cascade. Once the ring helicase is loaded, it recruits the primase an... Read More about DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings.

Advances in the understanding of susceptibility to treatment-related acute myeloid leukaemia (2004)
Journal Article
Seedhouse, C., & Russell, N. (2004). Advances in the understanding of susceptibility to treatment-related acute myeloid leukaemia. British Journal of Haematology, 137(6), 513-529. https://doi.org/10.1111/j.1365-2141.2007.06613.x

Treatment-related acute myeloid leukaemia (t-AML) is a devastating complication following exposure to the cytotoxic and genotoxic agents used to treat a primary malignancy. Whilst the incidence of t-AML is rising, it still only occurs in a minority o... Read More about Advances in the understanding of susceptibility to treatment-related acute myeloid leukaemia.

Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible mechanisms leading to an increased risk of t-AML/MDS (2004)
Journal Article
Fern, L., Pallis, M., Carter, G. I., Seedhouse, C., Russell, N., & Byrne, J. (2004). Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible mechanisms leading to an increased risk of t-AML/MDS. British Journal of Haematology, 126(1), 63-71. https://doi.org/10.1111/j.1365-2141.2004.05006.x

The molecular pathogenesis of therapy-related acute myeloid leukaemia/myelodysplastic syndrome (t-AML/MDS) remains uncertain. However, clonal haemopoiesis may develop following stem cell transplantation and precede the development of t-AML/MDS. Moreo... Read More about Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible mechanisms leading to an increased risk of t-AML/MDS.

A randomised controlled trial of a care home rehabilitation service to reduce long-term institutionalisation for elderly people (2004)
Journal Article
Fleming, S. A., Blake, H., Gladman, J. R., Hart, E., Lymbery, M., Dewey, M. E., McCloughry, H., Walker, M. F., & Miller, P. (in press). A randomised controlled trial of a care home rehabilitation service to reduce long-term institutionalisation for elderly people. Age and Ageing, 33(4), https://doi.org/10.1093/ageing/afh126

Objectives: to evaluate the effect of a care home rehabilitation service on institutionalisation, health outcomes and service use.

Design: randomised controlled trial, stratified by Barthel ADL index, social service sector and whether living alone... Read More about A randomised controlled trial of a care home rehabilitation service to reduce long-term institutionalisation for elderly people.

Molecular evidence links cryptic diversification in polar planktonic protists to Quaternary climate dynamics (2004)
Journal Article
Darling, K. F., Kucera, M., Pudsey, C. J., & Wade, C. M. (2004). Molecular evidence links cryptic diversification in polar planktonic protists to Quaternary climate dynamics. Proceedings of the National Academy of Sciences, 101(20), 7657-7662. https://doi.org/10.1073/pnas.0402401101

It is unknown how pelagic marine protists undergo diversification and speciation. Superficially, the open ocean appears homogeneous, with few clear barriers to gene flow, allowing extensive, even global, dispersal. Yet, despite the apparent lack of o... Read More about Molecular evidence links cryptic diversification in polar planktonic protists to Quaternary climate dynamics.

Expression of calpastatin isoforms in muscle and functionality of multiple calpastatin promoters (2004)
Journal Article
Parr, T., Jewell, K. K., Sensky, P. L., Brameld, J. M., Bardsley, R. G., & Buttery, P. J. (2004). Expression of calpastatin isoforms in muscle and functionality of multiple calpastatin promoters. Archives of Biochemistry and Biophysics, 427(1), 8-15. https://doi.org/10.1016/j.abb.2004.04.001

Calpastatin is the specific endogenous inhibitor of calpain proteinase that is encoded by a single gene. Transient transfection assays in both a non-fusing skeletal muscle and non-muscle cell-line demonstrated that the putative porcine calpastatin pr... Read More about Expression of calpastatin isoforms in muscle and functionality of multiple calpastatin promoters.

Vitamin A regulation of stearoyl-CoA desaturase mRNA levels and fatty acid composition in sheep tissues (2004)
Journal Article
Daniel, Z. C., Salter, A. M., & Buttery, P. J. (2004). Vitamin A regulation of stearoyl-CoA desaturase mRNA levels and fatty acid composition in sheep tissues. Animal Science, 78(2), 237-243. https://doi.org/10.1017/s1357729800054023

The effect of vitamin A (retinol) on ovine stearoyl-CoA desaturase (SCD) mRNA levels and fatty acid composition was investigated. Sheep adipose tissue explants were maintained in culture for 24 h in the presence of all-trans retinoic acid (RA). Tissu... Read More about Vitamin A regulation of stearoyl-CoA desaturase mRNA levels and fatty acid composition in sheep tissues.

Polymorphisms in Genes Involved in Homologous Recombination Repair Interact to Increase the Risk of Developing Acute Myeloid Leukemia (2004)
Journal Article
Seedhouse, C., Faulkner, R., Ashraf, N., Das-Gupta, E., & Russell, N. (2004). Polymorphisms in Genes Involved in Homologous Recombination Repair Interact to Increase the Risk of Developing Acute Myeloid Leukemia. Clinical Cancer Research, 10(8), 2675–2680. https://doi.org/10.1158/1078-0432.CCR-03-0372

Purpose: Double-strand break repair via homologous recombination is essential in maintaining genetic integrity. RAD51 and XRCC3 are involved in the repair of DNA by this pathway, and polymorphisms have been identified in both the RAD51 (RAD51-G135C)... Read More about Polymorphisms in Genes Involved in Homologous Recombination Repair Interact to Increase the Risk of Developing Acute Myeloid Leukemia.

Uranyl acetate speciation in aqueous solutions-An XAS study between 25°C and 250°C (2004)
Journal Article
Bailey, E. H., Mosselmans, J. F., & Schofield, P. F. (2004). Uranyl acetate speciation in aqueous solutions-An XAS study between 25°C and 250°C. Geochimica et Cosmochimica Acta, 68(8), 1711-1722. https://doi.org/10.1016/j.gca.2003.08.024

Speciation of uranium (VI) in acetate solutions between 25 and 250°C, at pH values between 1.8 and 3.8 and acetate/uranium (Ac/U) ratios of 0.5 to 100 has been investigated using uranium LIII-edge X-ray absorption spectroscopy. With increasing pH the... Read More about Uranyl acetate speciation in aqueous solutions-An XAS study between 25°C and 250°C.

Uranium biosorption by the lichen trapelia involuta at a uranium mine (2004)
Journal Article
Purvis, O. W., Bailey, E. H., McLean, J., Kasama, T., & Williamson, B. J. (2004). Uranium biosorption by the lichen trapelia involuta at a uranium mine. Geomicrobiology Journal, 21(3), 159-167. https://doi.org/10.1080/01490450490275398

Metal localisation was investigated in the lichenised ascomycete Trapelia involuta growing on a range of uraniferous minerals including metazeunerite [Cu(UO2)2(AsO42·8H2O], metatorbernite [Cu(UO22(PO4)2·8H2O], autunite [Ca(UO2)2(PO42·10H2O] and urani... Read More about Uranium biosorption by the lichen trapelia involuta at a uranium mine.