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Enhanced variant neutralization through glycan masking of SARS-CoV-2 XBB1.5 RBD (2025)
Journal Article
Olivier, J., George, C., Qingzhou Huang, C., Sujit, S. B., Tonks, P., Cantoni, D., Grove, J., O’Reilly, L., Geiger, J., Dohmen, C., Mummert, V., Rosalind Samuel, A., Plank, C., Kinsley, R., Temperton, N., Pfranger, M., Wagner, R., Heeney, J. L., Vishwanath, S., & Carnell, G. W. (2025). Enhanced variant neutralization through glycan masking of SARS-CoV-2 XBB1.5 RBD. Emerging Microbes & Infections, 14(1), Article 2502011. https://doi.org/10.1080/22221751.2025.2502011

Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network (2025)
Journal Article
Becker, Y., Eichner, C., Paquette, M., Bock, C., Girard-Buttoz, C., Jäger, C., Gräßle, T., Deschner, T., Zuberbühler, K., Wood, K., Wibbelt, G., Weiskopf, N., Walker, S., Unwin, S., Ulrich, R., Tanga, T., Szentiks, C. A., Southern, L., Stidworthy, M. F., Steiner, J., …Anwander, A. (2025). Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network. Nature Communications, 16(1), Article 4485. https://doi.org/10.1038/s41467-025-59254-8

The arcuate fascicle (AF) is the main fibre tract in the brain for human language. It connects frontal and temporal language areas in the superior and middle temporal gyrus (MTG). The AF’s connection to the MTG was considered unique to humans and has... Read More about Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network.

Efficiency of isoflurane capture from anaesthetised veterinary patients: a single-centre study of a volatile capture device (2025)
Journal Article
White, K., West, E., Yarnall, H., & Sparks, T. (2025). Efficiency of isoflurane capture from anaesthetised veterinary patients: a single-centre study of a volatile capture device. British Journal of Anaesthesia, 135(1), 276-278. https://doi.org/10.1016/j.bja.2025.03.034

Medical healthcare has been forward in acknowledging its greenhouse gas emissions, which contribute to the existential risk from climate change.1,2 There is similar concern in veterinary healthcare.3,4 An estimated 21% of the carbon emissions for a c... Read More about Efficiency of isoflurane capture from anaesthetised veterinary patients: a single-centre study of a volatile capture device.

AP2X-8 Is Important for Tachyzoite Growth and Bradyzoite Differentiation of Toxoplasma gondii (2025)
Journal Article
Sun, L.-X., Wang, M., Elsheikha, H. M., Xie, S.-C., Fu, B.-Q., Zhu, X.-Q., & Liu, G.-H. (2025). AP2X-8 Is Important for Tachyzoite Growth and Bradyzoite Differentiation of Toxoplasma gondii. Animals, 15(9), Article 1349. https://doi.org/10.3390/ani15091349

Toxoplasma gondii is a protozoan parasite capable of establishing chronic infections, with potential reactivation in immunocompromised individuals. However, the molecular mechanisms governing tachyzoite-to-bradyzoite differentiation remain incomplete... Read More about AP2X-8 Is Important for Tachyzoite Growth and Bradyzoite Differentiation of Toxoplasma gondii.

Anti-Müllerian hormone, antral follicle count, and progesterone evaluation in Italian Mediterranean buffalo heifers (2025)
Journal Article
Monti, S., la Spisa, M., Capuzzello, G., di Giorgio, S., Arfuso, F., & Marino, G. (2025). Anti-Müllerian hormone, antral follicle count, and progesterone evaluation in Italian Mediterranean buffalo heifers. Large Animal Review, 31(2), 67-70

Anti-Müllerian hormone (AMH) has been used as a molecular marker of the ovarian follicular pool and follicular responsiveness to superovulation treatments in cattle and other species. Early studies in buffalo cows indicated that circulating AMH level... Read More about Anti-Müllerian hormone, antral follicle count, and progesterone evaluation in Italian Mediterranean buffalo heifers.

Widespread pesticide pollution in two English river catchments of contrasting land-use: from sediments to fish (2025)
Journal Article
Ramage, C. I., Alfama Lopes dos Santos, R., Yon, L., Johnson, M. F., & Vane, C. H. (2025). Widespread pesticide pollution in two English river catchments of contrasting land-use: from sediments to fish. Environmental Pollution, 375, Article 126371. https://doi.org/10.1016/j.envpol.2025.126371

Water, sediments, fish and invertebrates were collected along two English rivers (R. Tone, Sommerset and R. Wensum, Norfolk) and analysed for 52 pesticides to assess source to sea spatial distribution and track bioaccumulation within wildlife. Chemic... Read More about Widespread pesticide pollution in two English river catchments of contrasting land-use: from sediments to fish.

In Silico–Based Investigation of the Immunogenicity and Biochemical Attributes of Toxoplasma gondii Apical Membrane Antigen 1 (TgAMA1) (2025)
Journal Article
Foroutan, M., Ghaffari, A. D., Ghaffarifar, F., Karimipour-Saryazdi, A., Birgani, A. A., Majidiani, H., Cortes, H., & Elsheikha, H. M. (2025). In Silico–Based Investigation of the Immunogenicity and Biochemical Attributes of Toxoplasma gondii Apical Membrane Antigen 1 (TgAMA1). Journal of Parasitology Research, https://doi.org/10.1155/japr/3514414

Background: Apical membrane antigen 1 (AMA1) is a highly conserved microneme protein in apicomplexan parasites. In this study, immunoinformatics tools and in silico protein structure prediction were used to characterize the structure, physicochemical... Read More about In Silico–Based Investigation of the Immunogenicity and Biochemical Attributes of Toxoplasma gondii Apical Membrane Antigen 1 (TgAMA1).

Environmental interference and declining male fertility (2025)
Journal Article
Lea, R. G. (2025). Environmental interference and declining male fertility. Reproduction, Fertility and Development, 37(7), Article RD25047. https://doi.org/10.1071/rd25047

Declining human male ‘fertility’ has been equated with a temporal decline in sperm counts, with reports collectively spanning the period between 1934 and 2018. Although sperm quality is impacted by adult male lifestyle choices, e.g. diet, stress and... Read More about Environmental interference and declining male fertility.

Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens (2025)
Journal Article
Hu, Z., Ai, H., Wang, Z., Huang, S., Sun, H., Xuan, X., Chen, M., Wang, J., Yan, W., Sun, J., Pu, J., Brooke, C. B., Chang, K.-C., Sun, Y., & Liu, J. (2025). Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens. npj Vaccines, 10(1), Article 67. https://doi.org/10.1038/s41541-025-01115-y

H9N2 avian influenza virus (AIV) is endemic in poultry worldwide and increasingly zoonotic. Despite the long-term widespread use of inactivated vaccines, H9N2 AIVs remain dominant in chicken flocks. We demonstrated that inactivated vaccines did not p... Read More about Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens.

Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes—An In Vitro Approach (2025)
Journal Article
Castanheira, C. I. G. D., Anderson, J. R., Clarke, E. J., Hackl, M., James, V., Clegg, P. D., & Peffers, M. J. (2025). Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes—An In Vitro Approach. International Journal of Molecular Sciences, 26(7), Article 3353. https://doi.org/10.3390/ijms26073353

This study describes a novel technique to analyze the extracellular vesicle (EV)-derived microRNA (miRNA) crosstalk between equine chondrocytes and synoviocytes. Donor cells (chon- drocytes, n=8; synoviocytes, n=9) were labelled with 5-ethynyl uridin... Read More about Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes—An In Vitro Approach.

Future crop breeding needs to consider future soils (2025)
Journal Article
Raza, S., Pandey, B. K., Hawkesford, M. J., Griffiths, S., Bennett, M. J., & Mooney, S. J. (2025). Future crop breeding needs to consider future soils. Nature Plants, 11, 939-941. https://doi.org/10.1038/s41477-025-01977-z

Modern crop breeding and seed certification agencies ignore the known spatial heterogeneity of soils and develop cultivars to thrive in a ‘one-size-fits-all’ soil environment. Neglecting the evolving dynamics of soils substantially undermines the cap... Read More about Future crop breeding needs to consider future soils.

Anatomy, Histology, Aetiology, Development and Functions of Cartilago Cordis: A Systematic Review (2025)
Journal Article
Kubale, V., Best, A., Mai, S., Smale, T., Alibhai, A., Perez, W., El-Gendy, S. A., Alsafy, M. A., Sturrock, C. J., & Rutland, C. S. (2025). Anatomy, Histology, Aetiology, Development and Functions of Cartilago Cordis: A Systematic Review. Cells Tissues Organs, https://doi.org/10.1159/000544776

Introduction:
The cartilago cordis is a structure present within the cardiac skeleton of some, but not all, vertebrate species. This systematic review compared the presence, structure, and function of the cartilago cordis from published works cover... Read More about Anatomy, Histology, Aetiology, Development and Functions of Cartilago Cordis: A Systematic Review.

Investigation of the genetic diversity of gut mycobiota of the wild and laboratory mice (2025)
Journal Article
Zhao, J.-X., Elsheikha, H. M., Shang, K.-M., Su, J.-W., Wei, Y.-J., Qin, Y., Zhao, Z.-Y., Ma, H., & Zhang, X.-X. (2025). Investigation of the genetic diversity of gut mycobiota of the wild and laboratory mice. Microbiology Spectrum, 13(5), Article e02840-24. https://doi.org/10.1128/spectrum.02840-24

Mice are colonized by diverse gut fungi, known as the mycobiota, which have received much less attention than bacterial microbiota. Here, we studied the diversities and structures of cecal fungal communities in wild (Lasiopodomys brandtii, Apodemus a... Read More about Investigation of the genetic diversity of gut mycobiota of the wild and laboratory mice.

Prevalence of Pentatrichomonas hominis infection in wild rodents (2025)
Journal Article
Tang, Y., Wang, H. T., Li, J. H., Hou, Q. Y., Qin, S. Y., Ma, H., Qin, Y., Zhao, Q., Elsheikha, H. M., & Liu, S. (2025). Prevalence of Pentatrichomonas hominis infection in wild rodents. BMC Veterinary Research, 21(1), Article 218. https://doi.org/10.1186/s12917-025-04604-3

Background
Pentatrichomonas hominis is a zoonotic pathogen linked to gastrointestinal diseases in various animal species and humans. However, its prevalence of in wild rodents remains unexplored. Therefore, investigating the prevalence and molecular... Read More about Prevalence of Pentatrichomonas hominis infection in wild rodents.

Progressive evolution of Streptococcus equi from Streptococcus equi subsp. zooepidemicus and adaption to equine hosts (2025)
Journal Article
Wilson, H. J., Dong, J., van Tonder, A. J., Ruis, C., Lefrancq, N., McGlennon, A., Bustos, C., Frosth, S., Léon, A., Blanchard, A. M., Holden, M., Waller, A. S., & Parkhill, J. (2025). Progressive evolution of Streptococcus equi from Streptococcus equi subsp. zooepidemicus and adaption to equine hosts. Microbial Genomics, 11(3), Article 001366. https://doi.org/10.1099/mgen.0.001366

Streptococcus equi subsp. equi causes the equine respiratory disease ‘strangles’, which is highly contagious, debilitating and costly to the equine industry. S. equi emerged from the ancestral Streptococcus equi subsp. zooepidemicus and continues to... Read More about Progressive evolution of Streptococcus equi from Streptococcus equi subsp. zooepidemicus and adaption to equine hosts.

Tuberculosis in found dead badgers at the edge of the expanding bovine tuberculosis epidemic (2025)
Journal Article
Powell, S. M., Dessi, N., Bennett, M., Wang, B., Robertson, A., Waller, E., Smith, G. C., & Delahay, R. J. (2025). Tuberculosis in found dead badgers at the edge of the expanding bovine tuberculosis epidemic. Scientific Reports, 15(1), Article 10547. https://doi.org/10.1038/s41598-025-86930-y

Bovine tuberculosis (bTB) is a major disease of cattle in the UK, placing a significant economic burden on the taxpayer. The causative agent, Mycobacterium bovis, has a wide host range, including the European badger (Meles meles). While badgers have... Read More about Tuberculosis in found dead badgers at the edge of the expanding bovine tuberculosis epidemic.

Neuroinflammation and schizophrenia: The role of Toxoplasma gondii infection and astrocytic dysfunction (2025)
Journal Article
Everett, A., & Elsheikha, H. M. (2025). Neuroinflammation and schizophrenia: The role of Toxoplasma gondii infection and astrocytic dysfunction. Journal of Neuroimmunology, 403, Article 578588. https://doi.org/10.1016/j.jneuroim.2025.578588

Obligate intracellular pathogens such as the protozoan Toxoplasma gondii exploit host cell mechanisms to facilitate their survival and replication. While T. gondii can infect any nucleated mammalian cell, it exhibits a particular affinity for central... Read More about Neuroinflammation and schizophrenia: The role of Toxoplasma gondii infection and astrocytic dysfunction.

Stakeholders' perspectives on communicating biosecurity to encourage behavior change in farmers (2025)
Journal Article
Moya, S., Lamont, K., Brennan, M. L., Ciavarino, G., Costa, M., Allepuz, A., Tamminen, L.-M., Correia-Gomes, C., De Carvalho Ferreira, H., Dogusan, M. M., Imperial, T., De Meneghi, D., Kjosevski, M., Chantziaras, I., & Burrell, A. (2025). Stakeholders' perspectives on communicating biosecurity to encourage behavior change in farmers. Frontiers in Veterinary Science, 12, Article 1562648. https://doi.org/10.3389/fvets.2025.1562648

Effective communication is crucial for strengthening collaboration and ensuring the successful implementation of biosecurity measures against infectious diseases. A collaborative approach, where farmers and veterinarians play a central role in decisi... Read More about Stakeholders' perspectives on communicating biosecurity to encourage behavior change in farmers.

Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity (2025)
Journal Article
Bingham, K., Zahrani, Y. A., Stewart, I., Portelli, M. A., Fogarty, A., McKeever, T. M., Singapuri, A., Heaney, L. G., Mansur, A. H., Chaudhuri, R., Thomson, N. C., Holloway, J. W., Howarth, P. H., Djukanovic, R., Blakey, J. D., Chauhan, A., Brightling, C. E., Pogson, Z. E., Hall, I. P., Martinez-Pomares, L., …Sayers, I. (2025). Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity. Immunity, Inflammation and Disease, 13(3), Article e70116. https://doi.org/10.1002/iid3.70116

Background:

Asthma is a heterogeneous disease characterized by overlapping clinical and inflammatory features.

Objective:

This study aimed to provide insight into the systemic inflammatory profile in asthma, greater understanding of asthma... Read More about Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity.