All Outputs (183)

Digital technology to facilitate Proactive Assessment of Obesity Risk during Infancy (ProAsk): a feasibility study (2017)
Journal Article
Redsell, S. A., Rose, J., Weng, S., Ablewhite, J., Swift, J. A., Siriwardena, A. N., Nathan, D., Wharrad, H. J., Atkinson, P., Watson, V., McMaster, F., Lakshman, R., & Glazebrook, C. (2017). Digital technology to facilitate Proactive Assessment of Obesity Risk during Infancy (ProAsk): a feasibility study. BMJ Open, 7(9), Article e017694. https://doi.org/10.1136/bmjopen-2017-017694

Objective: To assess the feasibility and acceptability of using digital technology for Proactive Assessment of Obesity Risk during Infancy (ProAsk) with the UK health visitors (HVs) and parents.

Design: Multicentre, pre- and post-intervention feas... Read More about Digital technology to facilitate Proactive Assessment of Obesity Risk during Infancy (ProAsk): a feasibility study.

Identification and characterization of the proteins bound by specific phage-displayed recombinant antibodies (scFv) obtained against Brazil nut and almond extracts (2017)
Journal Article
de la Cruz, S., Madrid, R., García, A., Alcocer, M., Martín, R., González, I., & García, T. (in press). Identification and characterization of the proteins bound by specific phage-displayed recombinant antibodies (scFv) obtained against Brazil nut and almond extracts. Journal of the Science of Food and Agriculture, 30(6), https://doi.org/10.1002/jsfa.8640

BACKGROUND

Almonds and Brazil nuts are widely consumed allergenic nuts whose presence must be declared according to food labelling regulations. Their detection in food products has been recently achieved by ELISA methods with recombinant antibodie... Read More about Identification and characterization of the proteins bound by specific phage-displayed recombinant antibodies (scFv) obtained against Brazil nut and almond extracts.

Proline as a Formic Acid Stress Protectant During Fermentation of Glucose to Ethanol by Saccharomyces spp. (2017)
Journal Article
Oshoma, C. E., Phister, T. G., Powell, C. D., Smart, K. A., & Du, C. (2017). Proline as a Formic Acid Stress Protectant During Fermentation of Glucose to Ethanol by Saccharomyces spp. Industrial Biotechnology, 13(4), 209-216. https://doi.org/10.1089/ind.2017.0017

During bioethanol production from lignocellulosic hydrolysates, yeasts are frequently exposed to various forms of fermentation stress. These include nutritional starvation, metabolites production, and fermentation inhibiting compounds produced during... Read More about Proline as a Formic Acid Stress Protectant During Fermentation of Glucose to Ethanol by Saccharomyces spp..

LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development (2017)
Journal Article
Sparrow, A. J., Sweetman, D., & Welham, S. J. (2017). LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development. Life Sciences, 186, 17-24. https://doi.org/10.1016/j.lfs.2017.07.034

Aims

Maternal dietary restriction during pregnancy impairs nephron development and results in offspring with fewer nephrons. Cell turnover in the early developing kidney is altered by exposure to maternal dietary restriction and may be regulated b... Read More about LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development.

The effects of probiotics and symbiotics on risk factors for hepatic encephalopathy (2017)
Journal Article
Viramontes Hörner, D., Avery, A., & Stow, R. (2017). The effects of probiotics and symbiotics on risk factors for hepatic encephalopathy. Journal of Clinical Gastroenterology, 51(4), 312-323. https://doi.org/10.1097/MCG.0000000000000789

Alterations in the levels of intestinal microbiota, endotoxemia, and inflammation are novel areas of interest in the pathogenesis of hepatic encephalopathy (HE). Probiotics and symbiotics are a promising treatment option for HE due to possible benefi... Read More about The effects of probiotics and symbiotics on risk factors for hepatic encephalopathy.

Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women (2017)
Journal Article
Alshammari, G., Khan, R., Brameld, J. M., Amer, S. A., & Lomax, M. A. (2017). Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women. European Review for Medical and Pharmacological Sciences, 21(5),

OBJECTIVE: The pathogenesis of polycystic ovary syndrome (PCOS), a common endocrine disease and metabolic disturbance, is still unknown. The aim of the study was to investigate whether patients with PCOS display increased expression of inflammatory m... Read More about Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women.

Associations between children's diet quality and watching television during meal or snack consumption: a systematic review (2017)
Journal Article
Avery, A., Anderson, C., & McCullough, F. (2017). Associations between children's diet quality and watching television during meal or snack consumption: a systematic review. Maternal and Child Nutrition, 13(4), Article e12428. https://doi.org/10.1111/mcn.12428

Studies have identified an association between watching television (TV) and childhood obesity. This review adds context to existing research by examining the associations between TV viewing, whilst eating, and children's diet quality. Web of Science... Read More about Associations between children's diet quality and watching television during meal or snack consumption: a systematic review.

Fetal and neonatal exposure to trans fatty acids impacts on susceptibility to atherosclerosis in apolipoprotein E*3 Leiden mice (2017)
Journal Article
Salter, A. M., Langley-Evans, S. C., Gates, L., Lock, A. L., & Kraft, J. (2017). Fetal and neonatal exposure to trans fatty acids impacts on susceptibility to atherosclerosis in apolipoprotein E*3 Leiden mice. British Journal of Nutrition, 117(3), 377-385. https://doi.org/10.1017/S0007114517000137

Nutrition during pregnancy can impact on the susceptibility of the offspring to cardiovascular disease. Postnatal consumption of trans fatty acids (TFA), associated with partially hydrogenated vegetable oil (PHVO), increases the risk of atheroscleros... Read More about Fetal and neonatal exposure to trans fatty acids impacts on susceptibility to atherosclerosis in apolipoprotein E*3 Leiden mice.

Factors associated with universal infant free school meal take up and refusal in a multicultural urban community (2017)
Journal Article
Goodchild, G., Faulks, J., Swift, J., Mhesuria, J., Jethwa, P., & Pearce, J. (2017). Factors associated with universal infant free school meal take up and refusal in a multicultural urban community. Journal of Human Nutrition and Dietetics, 30(4), 417-428. https://doi.org/10.1111/jhn.12442

Background

Universal infant free school meals (UIFSM) were introduced in September 2014 and are available to all key stage 1 (4–7 years) children attending state-maintained infant and primary schools in England. The present study aimed to investig... Read More about Factors associated with universal infant free school meal take up and refusal in a multicultural urban community.

Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism (2017)
Journal Article
Welham, S. J., Sparrow, A. J., Gardner, D. S., & Elmes, M. J. (2017). Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism. World Journal of Nephrology, 6(1), https://doi.org/10.5527/WJN.v6.i1.21

AIM: To evaluate the effects of the non-selective, non-steroidal anti-inflammatory drug (NSAID) acetylsalicylic acid (ASA), on ex vivo embryonic kidney growth and development.
METHODS: Pairs of fetal mouse kidneys at embryonic day 12.5 were cultured... Read More about Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism.

Factors influencing engagement in postnatal weight management and subsequent weight and well-being outcomes (2016)
Journal Article
Avery, A., Hillier, S., Pallister, C., Barber, J., & Lavin, J. (in press). Factors influencing engagement in postnatal weight management and subsequent weight and well-being outcomes. British Journal of Midwifery, 24(11), https://doi.org/10.12968/bjom.2016.24.11.806

Many women exceed gestational weight gain recommendations. Successful postnatal weight management decreases the risk of entering further pregnancies obese. This service evaluation investigates women’s motivations to lose weight postnatally, the weigh... Read More about Factors influencing engagement in postnatal weight management and subsequent weight and well-being outcomes.

Dietitians' practice in giving carbohydrate advice in the management of type 2 diabetes: a mixed methods study (2016)
Journal Article
McArdle, P. D., Greenfield, S. M., Avery, A., Adams, G. G., & Gill, P. S. (in press). Dietitians' practice in giving carbohydrate advice in the management of type 2 diabetes: a mixed methods study. Journal of Human Nutrition and Dietetics, 30(3), https://doi.org/10.1111/jhn.12436

Background: Carbohydrate is accepted as the principal nutrient affecting blood glucose in diabetes; however, current guidelines are unable to specify the optimal quantity of carbohydrate for glycaemic control. No studies exist that describe current p... Read More about Dietitians' practice in giving carbohydrate advice in the management of type 2 diabetes: a mixed methods study.

Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS) (2016)
Journal Article
Perkins, S. J., Wright, D. W., Zhang, H., Brookes, E. H., Chen, J., Irving, T. C., Krueger, S., Barlow, D. J., Edler, K. J., Scott, D. J., Terrill, N. J., King, S. M., Butler, P. D., & Curtis, J. E. (2016). Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS). Journal of Applied Crystallography, 49(6), 1861-1875. https://doi.org/10.1107/S160057671601517X

The capabilities of current computer simulations provide a unique opportunity to model small-angle scattering (SAS) data at the atomistic level, and to include other structural constraints ranging from molecular and atomistic energetics to crystallog... Read More about Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS).

Antenatal weight management: women’s experiences, behaviours, and expectations of weighing in early pregnancy (2016)
Journal Article
Swift, J. A., Pearce, J., Jethwa, P., Taylor, M. A., Avery, A., Ellis, S., Langley-Evans, S. . C., & McMullen, S. (2016). Antenatal weight management: women’s experiences, behaviours, and expectations of weighing in early pregnancy. Journal of Pregnancy, Article 8454759. https://doi.org/10.1155/2016/8454759

The current emphasis on obstetric risk management helps to frame gestational weight gain as problematic and encourages intervention by healthcare professionals. However pregnant women have reported confusion, distrust, and negative affect associated... Read More about Antenatal weight management: women’s experiences, behaviours, and expectations of weighing in early pregnancy.

Transcription of the apicoplast genome (2016)
Journal Article
Nisbet, R., & McKenzie, J. (2016). Transcription of the apicoplast genome. Molecular and Biochemical Parasitology, 210(1-2), 5-9. https://doi.org/10.1016/j.molbiopara.2016.07.004

Many members of the Apicomplexa contain a remnant chloroplast, known as an apicoplast. The apicoplast encodes numerous genes, and loss of the organelle is lethal. Here, we present a summary of what is known about apicoplast transcription. Unlike plan... Read More about Transcription of the apicoplast genome.

Improving the sustainability of global meat and milk production (2016)
Journal Article
Salter, A. M. (2017). Improving the sustainability of global meat and milk production. Proceedings of the Nutrition Society, 76(1), https://doi.org/10.1017/S0029665116000276

Global demand for meat and dairy products has increased dramatically in recent decades and, through a combination of global population growth, increased lifespan and improved economic prosperity in the developing world will inevitably continue to inc... Read More about Improving the sustainability of global meat and milk production.

Transcripts in the Plasmodium Apicoplast Undergo Cleavage at tRNAs and Editing, and Include Antisense Sequences (2016)
Journal Article
Nisbet, R. E. R., Kurniawan, D. P., Bowers, H. D., & Howe, C. J. (2016). Transcripts in the Plasmodium Apicoplast Undergo Cleavage at tRNAs and Editing, and Include Antisense Sequences. Protist, 167(4), 377-388. https://doi.org/10.1016/j.protis.2016.06.003

The apicoplast, an organelle found in Plasmodium and many other parasitic apicomplexan species, is a remnant chloroplast that is no longer able to carry out photosynthesis. Very little is known about primary transcripts and RNA processing in the Plas... Read More about Transcripts in the Plasmodium Apicoplast Undergo Cleavage at tRNAs and Editing, and Include Antisense Sequences.

Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes (2016)
Journal Article
Murton, A. J., Maddocks, M., Stephens, F. B., Marimuthu, K., England, R., & Wilcock, A. (in press). Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes. Clinical Lung Cancer, https://doi.org/10.1016/j.cllc.2016.06.003

Introduction: Loss of muscle is common in patients with advanced non-small cell lung cancer (NSCLC), and contributes to the high morbidity and mortality of this group. The exact mechanisms behind the loss of muscle are unclear.
Patients and methods... Read More about Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes.

Setting targets leads to greater long-term weight losses and ‘unrealistic’ targets increase the effect in a large community-based commercial weight management group (2016)
Journal Article
Avery, A., Langley-Evans, S. . C., Harrington, M., & Swift, J. A. (2016). Setting targets leads to greater long-term weight losses and ‘unrealistic’ targets increase the effect in a large community-based commercial weight management group. Journal of Human Nutrition and Dietetics, 29(6), 687-696. https://doi.org/10.1111/jhn.12390

Background. Setting personal targets is an important behavioural component in weight management programmes. Normal practice is to encourage ‘realistic’ weight loss but the under-pinning evidence base for this is limited and controversial. This study... Read More about Setting targets leads to greater long-term weight losses and ‘unrealistic’ targets increase the effect in a large community-based commercial weight management group.

Improving efficiency in meat production (2016)
Journal Article
Brameld, J. M., & Parr, T. (in press). Improving efficiency in meat production. Proceedings of the Nutrition Society, https://doi.org/10.1017/S0029665116000161

Selective breeding and improved nutritional management over the past 20–30 years has resulted in dramatic improvements in growth efficiency for pigs and poultry, particularly lean tissue growth. However, this has been achieved using high-quality feed... Read More about Improving efficiency in meat production.