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Five years of patient and public involvement and engagement (PPIE) in the development and evaluation of the Pain-at-Work Toolkit to support employees’ self-management of chronic pain at work (2025)
Journal Article
Blake, H., Abbott-Fleming, V., Greaves, S., Somerset, S., Chaplin, W. J., Wainwright, E., & Walker-Bone, K. (2025). Five years of patient and public involvement and engagement (PPIE) in the development and evaluation of the Pain-at-Work Toolkit to support employees’ self-management of chronic pain at work. Research Involvement and Engagement, 11, Article 81. https://doi.org/10.1186/s40900-025-00757-5

Background
Patient and public involvement and engagement (PPIE) is essential for the design, delivery and dissemination of high-quality, meaningful research. However, reporting of PPIE contributions is seldom transparent or consistent. We aimed to d... Read More about Five years of patient and public involvement and engagement (PPIE) in the development and evaluation of the Pain-at-Work Toolkit to support employees’ self-management of chronic pain at work.

Trajectory of hematoma growth and functional recovery after intracerebral hemorrhage: a latent class analysis of BASC data (2025)
Journal Article
Ouyang, M., You, S., Moullaali, T. J., Delcourt, C., Sandset, E., Woodhouse, L., Kang Law, Z., Arima, H., Butcher, K., Stephen, L., Mbbs, E., Gupta, S., Jiang, W., Koch, S., Potter, J., Qureshi, A. I., Robinson, T. G., Al-Shahi, R., Phd, S., Saver, J. L., …Wang, X. (in press). Trajectory of hematoma growth and functional recovery after intracerebral hemorrhage: a latent class analysis of BASC data. Cerebrovascular Diseases,

ImproviNg Tic services in EnglaND: A multi-method study to explore existing healthcare service provision for children and young people with tics and Tourette Syndrome (2025)
Journal Article
Rattu, N. R., Hall, S. S., Hall, C. L., Murphy, T., Kilgariff, J., James, N., McNally, E., Jeayes, A., Khan, K., Rimmer, S., Thomson, L., & Groom, M. J. (2025). ImproviNg Tic services in EnglaND: A multi-method study to explore existing healthcare service provision for children and young people with tics and Tourette Syndrome. BMJ Mental Health, 28(1), Article e301599. https://doi.org/10.1136/bmjment-2025-301599

Background Timely access to diagnostic assessment and treatment is essential to improve function and mitigate the risk of poor long-term outcomes in children and young people (CYP) with tics.

Objective This study aimed to explore i) how tic servic... Read More about ImproviNg Tic services in EnglaND: A multi-method study to explore existing healthcare service provision for children and young people with tics and Tourette Syndrome.

James Lind Alliance Priority Setting Partnership in co-existing dementia and hearing conditions: a research agenda defined by people with lived experience and healthcare professionals (2025)
Journal Article
Heffernan, E., Calvert, S., Dening, T., Broome, E., Spriggs, R., Ahmad, N., Lerigo-Smith, N., & Henshaw, H. (2025). James Lind Alliance Priority Setting Partnership in co-existing dementia and hearing conditions: a research agenda defined by people with lived experience and healthcare professionals. Age and Ageing, 54(7), Article afaf191. https://doi.org/10.1093/ageing/afaf191

Background
Dementia and hearing conditions are both major public health concerns. Most people living with dementia also live with hearing conditions (e.g. hearing loss, tinnitus, vestibular disorders). Furthermore, hearing loss may be a risk factor... Read More about James Lind Alliance Priority Setting Partnership in co-existing dementia and hearing conditions: a research agenda defined by people with lived experience and healthcare professionals.

17-year trends in radiological disease burden of multiple sclerosis at presentation (2025)
Journal Article
Taylor, M., Alrawashdeh, O., Evangelou, N., & Garjani, A. (2025). 17-year trends in radiological disease burden of multiple sclerosis at presentation. Multiple Sclerosis and Related Disorders, 102, Article 106607. https://doi.org/10.1016/j.msard.2025.106607

At a population level, MS disease progression appears to have slowed in recent years. This study assessed whether earlier detection of people with potentially milder radiological disease is contributing to these observed trends in MS disease course.... Read More about 17-year trends in radiological disease burden of multiple sclerosis at presentation.

Managing Minds at Work: A Feasibility Pilot Cluster Randomised Controlled Trial of a Web-based Interactive Training for Managers to Promote Mental Health at Work (2025)
Journal Article
Hassard, J., Blake, H., Dulal-Arthur, T., Frost, A., Bartle, C., Yarker, J., Munir, F., Vaughan, B., Daly, G., Meyer, C., Russell, S., & Thomson, L. (in press). Managing Minds at Work: A Feasibility Pilot Cluster Randomised Controlled Trial of a Web-based Interactive Training for Managers to Promote Mental Health at Work. JMIR Mental Health,

Angiotensin II and Cardiovascular Disease: Balancing Pathogenic and Protective Pathways (2025)
Journal Article
Bayraktutan, U. (2025). Angiotensin II and Cardiovascular Disease: Balancing Pathogenic and Protective Pathways. Current Issues in Molecular Biology, 47(7), Article 501. https://doi.org/10.3390/cimb47070501

The renin-angiotensin-aldosterone system (RAAS) is a hormone system that controls blood pressure and fluid and electrolyte balance. Angiotensin II, a key effector, is produced from angiotensin I by angiotensin-converting enzyme (ACE) and exerts its e... Read More about Angiotensin II and Cardiovascular Disease: Balancing Pathogenic and Protective Pathways.

Pramipexole augmentation for the acute phase of treatment-resistant, unipolar depression: a placebo- controlled, double-blind, randomised trial in the UK (2025)
Journal Article
Browning, M., Cowen, P. J., Galal, U., Baldwin, A., Cleare, A. J., Evans, J., Huys, Q. J. M., Kessler, D., Kurkar, M., Nixon, N., Rastogi, A., Watson, S., Yu, L.-M., Mort, S., Simon, J., Laszewska, A., Lewis, A. C., Roberts, S. M., Fiske, V., Frending, L. M., …Geddes, J. R. (2025). Pramipexole augmentation for the acute phase of treatment-resistant, unipolar depression: a placebo- controlled, double-blind, randomised trial in the UK. Lancet Psychiatry, https://doi.org/10.1016/S2215-0366%2825%2900194-4

Background
About 30% of patients with depression treated with antidepressant medication do not respond sufficiently to the first agents used. Pramipexole might usefully augment antidepressant medication in such cases of treatment-resistant depressio... Read More about Pramipexole augmentation for the acute phase of treatment-resistant, unipolar depression: a placebo- controlled, double-blind, randomised trial in the UK.

Management of co-existing dementia and hearing loss in social care settings: a focus group study (2025)
Journal Article
Broome, E. E., & Green, A. (in press). Management of co-existing dementia and hearing loss in social care settings: a focus group study. Dementia, https://doi.org/10.1177/14713012251356010

Background and Objectives:
Dementia and hearing loss are highly prevalent and increase in prevalence and severity with age. Hearing loss is often overlooked in people living with dementia, resulting in under-diagnosis and lack of appropriate manage... Read More about Management of co-existing dementia and hearing loss in social care settings: a focus group study.

Optimising access to vocational rehabilitation through multiple sclerosis charities: Protocol for a feasibility randomised controlled trial (2025)
Journal Article
De Dios Perez, B., Kendrick, D., das Nair, R., Evangelou, N., Newsome, I., & Radford, K. (2025). Optimising access to vocational rehabilitation through multiple sclerosis charities: Protocol for a feasibility randomised controlled trial. PLoS ONE, 20(6), Article e0325570. https://doi.org/10.1371/journal.pone.0325570

Background

People with multiple sclerosis (MS) often leave the workforce prematurely due to MS symptoms and difficulties managing workplace relationships and performance. Vocational rehabilitation (VR) can improve job retention outcomes for people... Read More about Optimising access to vocational rehabilitation through multiple sclerosis charities: Protocol for a feasibility randomised controlled trial.

The acceptability and effectiveness of standardised diagnostic assessment approaches in children and young people's mental health services: An updated systematic review (2025)
Journal Article
Basheer, S., Tan, S. F., David, R., Majumder, P., & Sayal, K. (2025). The acceptability and effectiveness of standardised diagnostic assessment approaches in children and young people's mental health services: An updated systematic review. Child and Adolescent Mental Health, https://doi.org/10.1111/camh.70007

Background: Standardised Diagnostic Assessment (SDA) tools are designed to comprehensively evaluate various mental health disorders and support accurate diagnoses. While evidence for their routine use in Child and Adolescent Mental Health Services (C... Read More about The acceptability and effectiveness of standardised diagnostic assessment approaches in children and young people's mental health services: An updated systematic review.

Outcomes of patient and public involvement in the development of the Cognitive Decline after Brain Radiosurgery (CoDe B-Rad) study: refining the research question and methodology (2025)
Journal Article
Bangiri, A., Horobin, A., Baker, J., Pszczolkowski, S., Thust, S., & Morgan, P. S. (2025). Outcomes of patient and public involvement in the development of the Cognitive Decline after Brain Radiosurgery (CoDe B-Rad) study: refining the research question and methodology. BMJ Open, 15(6), Article e094788. https://doi.org/10.1136/bmjopen-2024-094788

Objectives

Patient and public involvement (PPI) was sought in the development of the protocol for the Cognitive Decline after Brain Radiosurgery (CoDe B-Rad) study, which aims to identify potential side effects of stereotactic radiosurgery (SRS).... Read More about Outcomes of patient and public involvement in the development of the Cognitive Decline after Brain Radiosurgery (CoDe B-Rad) study: refining the research question and methodology.

Macrocyclic transition-metal parashift complexes for MRI at clinical and pre-clinical magnetic fields (2025)
Journal Article
Rogers, N. J., Ashok Kumar, C., Alexander, C., Bowdery, D., Pavlovskaya, G., & Harvey, P. (2025). Macrocyclic transition-metal parashift complexes for MRI at clinical and pre-clinical magnetic fields. Dalton Transactions, 54, 11036-11046. https://doi.org/10.1039/d5dt01149c

A series of macrocyclic transition-metal complexes, including Fe(II), Co(II), Ni(II), and Cu(II) complexes, have been evaluated for parashift MRI imaging applications, by assessing their paramagnetic NMR properties, including proton chemical shifts,... Read More about Macrocyclic transition-metal parashift complexes for MRI at clinical and pre-clinical magnetic fields.

Understanding the audiological care of patients with co-existing dementia or mild cognitive impairment and hearing loss in the United Kingdom National Health Service: A qualitative study (2025)
Journal Article
Calvert, S., Chitty, A., Langdon, A., Broome, E., Henshaw, H., Somerset, S., Dening, T., & Heffernan, E. (2025). Understanding the audiological care of patients with co-existing dementia or mild cognitive impairment and hearing loss in the United Kingdom National Health Service: A qualitative study. PLoS ONE, 26(6), Article e0327248. https://doi.org/10.1371/journal.pone.0327248

Background

Hearing loss is common among people living with dementia and can exacerbate the symptoms associated with dementia. The effective management of hearing loss can positively impact quality of life and help alleviate dementia-related sympto... Read More about Understanding the audiological care of patients with co-existing dementia or mild cognitive impairment and hearing loss in the United Kingdom National Health Service: A qualitative study.

Disassociating cerebral vasomotion from low frequency spontaneous neurovascular coupling (2025)
Preprint / Working Paper
Wang, R., Patel, P., Boorman, L., Okun, M., Howarth, C., & Berwick, J. (2025). Disassociating cerebral vasomotion from low frequency spontaneous neurovascular coupling

Vasomotion, vascular oscillations at ∼0.1 Hz, may serve as a biomarker and therapeutic target for neurodegenerative diseases, but its origins, structure across brain vasculature, and correlation with neural activity remain unclear. This study examine... Read More about Disassociating cerebral vasomotion from low frequency spontaneous neurovascular coupling.

Effects of hearing loss on semantic prediction: Delayed prediction for intelligible speech when listening is demanding (2025)
Journal Article
Fernandez, L. B., Shehzad, M., & Hadley, L. V. (2025). Effects of hearing loss on semantic prediction: Delayed prediction for intelligible speech when listening is demanding. Ear and Hearing, https://doi.org/10.1097/AUD.0000000000001679

Objectives: Linguistic context can be used during speech listening to predict what a talker will say next. These predictions may be particularly useful in adverse listening conditions, since they can facilitate speech processing. In this study we inv... Read More about Effects of hearing loss on semantic prediction: Delayed prediction for intelligible speech when listening is demanding.

Quantitative and Qualitative Outcomes of Non-Violent Resistance (NVR) Interventions for Children and Adolescents with Emotional and Behavioural Difficulties and their Caregivers – A Systematic Review (2025)
Journal Article
Awoyemi, B., May, L., David, R., Majumder, P., & Sayal, K. (2025). Quantitative and Qualitative Outcomes of Non-Violent Resistance (NVR) Interventions for Children and Adolescents with Emotional and Behavioural Difficulties and their Caregivers – A Systematic Review. Adoption and Fostering, https://doi.org/10.1177/03085759251340

Background

Non-Violent Resistance (NVR) is an approach of parent training developed to respond to child behavioural difficulties including aggression and risk-taking behaviours. NVR is offered in child and adolescent mental health services across... Read More about Quantitative and Qualitative Outcomes of Non-Violent Resistance (NVR) Interventions for Children and Adolescents with Emotional and Behavioural Difficulties and their Caregivers – A Systematic Review.

Atlas-Based Templates vs. Subject-Specific Tractography: Resolving the Debate (2025)
Journal Article
Schilling, K. G., Zhang, F., Tournier, J.-D., Vergani, F., Sotiropoulos, S. N., Rokem, A., & O’Donnell, L. J. (in press). Atlas-Based Templates vs. Subject-Specific Tractography: Resolving the Debate. Brain Structure and Function,

The first annual International Society of Tractography (IST) debate in Corsica in 2024 explored key challenges and controversies in tractography. This article examines the debate sparked by the provocative statement, "Tractography cannot give us anyt... Read More about Atlas-Based Templates vs. Subject-Specific Tractography: Resolving the Debate.