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All Outputs (7)

Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review (2019)
Journal Article
Essat, M., Archer, R., Williams, I., Zarotti, N., Coates, E., Clowes, M., Beever, D., Hackney, G., White, S., Stavroulakis, T., White, D., Norman, P., & McDermott, C. (2020). Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review. Clinical Nutrition, 39(8), 2547-2556. https://doi.org/10.1016/j.clnu.2019.11.015

Background & aims
Weight loss is common in people with neurodegenerative diseases of the motor system (NDMS), such as Parkinson's disease and Amyotrophic Lateral Sclerosis, and is associated with reduced quality of life, functional ability and survi... Read More about Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review.

An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units (2019)
Journal Article
Beever, D., & Swaby, L. (2019). An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units. Trials, 20(1), Article 556. https://doi.org/10.1186/s13063-019-3619-6

Background
Good Clinical Practice guidelines issued in 2016 encourage risk-based approaches to monitoring clinical trials. This study compared current risk assessment and monitoring approaches in UK Clinical Trials Units (CTUs) with the published gu... Read More about An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units.

ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol (2019)
Journal Article
van Berkel, D., Ong, T., Drummond, A., Hendrick, P., Leighton, P., Jones, M., Salem, K., Quraishi, N., Brookes, C., Suazo Di Paola, A., Edwards, S., & Sahota, O. (2019). ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol. BMJ Open, 9(7), Article 032111. https://doi.org/10.1136/bmjopen-2019-032111

Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study (2019)
Journal Article
Coupland, C. A., Hill, T., Dening, T., Morriss, R., Moore, M., & Hippisley-Cox, J. (2019). Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Internal Medicine, 179(8), 1084-1093. https://doi.org/10.1001/jamainternmed.2019.0677

IMPORTANCE Anticholinergic medicines have short-term cognitive adverse effects, but it
is uncertain whether long-term use of these drugs is associated with an increased risk of dementia.

OBJECTIVE To assess associations between anticholinergic dr... Read More about Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study.

Interventions for hand eczema (2019)
Journal Article
Christoffers, W., Coenraads, P.-J., Svensson, Å., Diepgen, T., Dickinson-Blok, J., Xia, J., & Williams, H. (2019). Interventions for hand eczema. Cochrane Database of Systematic Reviews, 2019(4), Article CD004055. https://doi.org/10.1002/14651858.CD004055.pub2

Background
Hand eczema is an inflammation of the skin of the hands that tends to run a chronic, relapsing course. This common condition is often associated with itch, social stigma, and impairment in employment. Many different interventions of unkno... Read More about Interventions for hand eczema.