All Outputs (239)

The development of a food-group, tree classification method and its use in exploring dietary associations with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) and other health-related outcomes in a UK Population (2025)
Journal Article
Alawadi, A. A., Vijay, A., Grove, J. I., Taylor, M. A., & Aithal, G. P. (2025). The development of a food-group, tree classification method and its use in exploring dietary associations with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) and other health-related outcomes in a UK Population. Metabolism Open, 100351. https://doi.org/10.1016/j.metop.2025.100351

Background
Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) affects up to one in five people in the UK, with persistent overeating and a sedentary lifestyle being significant risk factors. Exploring dietary patterns at a food level i... Read More about The development of a food-group, tree classification method and its use in exploring dietary associations with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) and other health-related outcomes in a UK Population.

Towards a common definition of hospital-acquired deconditioning in adults: a scoping review (2025)
Journal Article
Westlake, M., Cowley, A., Robinson, K., & Gordon, A. L. (2025). Towards a common definition of hospital-acquired deconditioning in adults: a scoping review. BMJ Open, 15, Article e086976. https://doi.org/10.1136/bmjopen-2024-086976

Background Hospital-acquired deconditioning is a term used in clinical practice, describing a loss of physical and/or cognitive function associated with hospitalisation. Previous reviews have addressed interventions, its prevalence in older adults an... Read More about Towards a common definition of hospital-acquired deconditioning in adults: a scoping review.

Towards a common definition of Hospital-Acquired Deconditioning in Adults: A Scoping Review (2025)
Journal Article
Westlake, M., Cowley, A., Robinson, K., & Gordon, A. L. (2025). Towards a common definition of Hospital-Acquired Deconditioning in Adults: A Scoping Review. BMJ Open, 15(1), Article e086976. https://doi.org/10.1136/bmjopen-2024-086976

Background: Hospital-acquired deconditioning is a term utilised in clinical practice, describing a loss of physical and/or cognitive function associated with hospitalisation. Previous reviews have addressed interventions, its prevalence in older adul... Read More about Towards a common definition of Hospital-Acquired Deconditioning in Adults: A Scoping Review.

Comparative effectiveness of various exercise interventions on central sensitisation indices: A systematic review and network meta-analysis (2025)
Journal Article
Ibrahim, A. A. E., McWilliams, D. F., Smith, S. L., Chaplin, W. J., Salimian, M., Georgopoulos, V., Kouraki, A., & Walsh, D. A. (2025). Comparative effectiveness of various exercise interventions on central sensitisation indices: A systematic review and network meta-analysis. Annals of Physical and Rehabilitation Medicine, 68(4), Article 101894. https://doi.org/10.1016/j.rehab.2024.101894

Background: Central sensitisation (CS) increases musculoskeletal pain. Quantitative sensory testing (QST) or self-report questionnaires might indicate CS. Indices of CS might be suppressed by exercise, although the optimal exercise regimen remains un... Read More about Comparative effectiveness of various exercise interventions on central sensitisation indices: A systematic review and network meta-analysis.

Piloting a minimum data set for older people living in care homes in England: a developmental study (2025)
Journal Article
Gordon, A. L., Rand, S., Crellin, E., Allan, S., Tracey, F., De Corte, K., Lloyd, T., Brine, R., Carroll, R. E., Towers, A.-M., Burton, J. K., Akdur, G., Hanratty, B., Webster, L., Palmer, S., Jones, L., Meyer, J., Spilsbury, K., Killett, A., Wolters, A. T., …Goodman, C. (2025). Piloting a minimum data set for older people living in care homes in England: a developmental study. Age and Ageing, 54(1), Article afaf001. https://doi.org/10.1093/ageing/afaf001

Background
We developed a prototype minimum data set (MDS) for English care homes, assessing feasibility of extracting data directly from digital care records (DCRs) with linkage to health and social care data.

Methods
Through stakeholder devel... Read More about Piloting a minimum data set for older people living in care homes in England: a developmental study.

Health care assistant and registered nurse dyads, working together and apart – a qualitative study (2024)
Journal Article
Carroll, R. E., De Vries, K., Goodman, C., & Brown, J. (2024). Health care assistant and registered nurse dyads, working together and apart – a qualitative study. BMC Nursing, 23(1), Article 954. https://doi.org/10.1186/s12912-024-02619-z

Background: This study was undertaken to understand the role of the Health Care Assistants and how they negotiate roles and responsibilities with Registered Nurses in adult acute hospitals. Methods: The qualitative approach of focused ethnography use... Read More about Health care assistant and registered nurse dyads, working together and apart – a qualitative study.

Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data (2024)
Journal Article
Cipolletta, E., Nakafero, G., McCormick, N., Yokose, C., Avery, A., Mamas, M., Choi, H., Tata, L., & Abhishek, A. (2024). Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data. The Lancet Rheumatology, https://doi.org/10.1016/S2665-9913%2824%2900248-0

Background
Initiating urate-lowering therapy can trigger gout flares. Gout flares have been associated with a temporally increased risk of cardiovascular events. Therefore, we aimed to estimate the risk of cardiovascular events in patients with gout... Read More about Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data.

Development and internal–external cross-validation of a patient-reported definition for acute calcium pyrophosphate crystal arthritis (2024)
Journal Article
Cipolletta, E., Rozza, D., Andres, M., Ottaviani, S., Pascart, T., Calvo-Aranda, E., Chiarvetto Peralta, M. V., Muto, P., Calabuig, I., Gómez-Sabater, S., Caño, R., Léger, B., Pacaud, A., Moscioni, E., Bruno, C., Caira, V., Gómez-González, C., Rosa, J. E., Nakafero, G., Filippucci, E., & Abhishek, A. (2024). Development and internal–external cross-validation of a patient-reported definition for acute calcium pyrophosphate crystal arthritis. Rheumatology, Article keae681. https://doi.org/10.1093/rheumatology/keae681

Objective
To develop and validate a patient-reported definition of acute calcium pyrophosphate (CPP) crystal arthritis in people with crystal-proven CPP deposition (CPPD) disease.

Methods
Consecutive patients with crystal-proven CPPD disease fro... Read More about Development and internal–external cross-validation of a patient-reported definition for acute calcium pyrophosphate crystal arthritis.

Cross-sectional study assessing the feasibility of measuring residents’ Quality of Life in English care homes and assessing the construct validity and internal consistency of measures completed by staff-proxy (2024)
Journal Article
Towers, A.-M., Rand, S., Allan, S., Webster, L., Palmer, S., E. Carroll, R., L Gordon, A., Akdur, G., Smith, N., Burton, J., Killett, A., Hanratty, B., Meyer, J., Spilsbury, K., & Goodman, C. (in press). Cross-sectional study assessing the feasibility of measuring residents’ Quality of Life in English care homes and assessing the construct validity and internal consistency of measures completed by staff-proxy. BMJ Open,

Objectives: To assess the feasibility of capturing older care home residents’ quality of life (QoL) in digital social care records and the construct validity (hypothesis testing) and internal consistency (Cronbach’s Alpha) of four QoL measures. Desig... Read More about Cross-sectional study assessing the feasibility of measuring residents’ Quality of Life in English care homes and assessing the construct validity and internal consistency of measures completed by staff-proxy.

The rat osteoarthritis bone score for histological pathology relevant to human bone marrow lesions and pain (2024)
Journal Article
McWilliams, D. F., Shahtaheri, M., Koushesh, S., Joseph, C., Gowler, P. R., Xu, L., Chapman, V., Sofat, N., & Walsh, D. A. (2025). The rat osteoarthritis bone score for histological pathology relevant to human bone marrow lesions and pain. Osteoarthritis and Cartilage Open, 7(1), Article 100544. https://doi.org/10.1016/j.ocarto.2024.100544

Objectives
Histological osteochondral characteristics of inflammation, fibrosis, vascularity, cartilage islands, vessels entering cartilage, thickened trabeculae and cysts are associated with bone marrow lesions (BMLs) in human knee osteoarthritis (... Read More about The rat osteoarthritis bone score for histological pathology relevant to human bone marrow lesions and pain.

Predictors of care home resident conveyance to hospital or referral to community pathways by a regional ambulance service attending medical emergencies: a retrospective cross sectional study (2024)
Journal Article
Siriwardena, A. N., Botan, V., Law, G., Laparidou, D., Phung, V.-H., Curtis, F., Whitley, G. A., Akanuwe, J., Rowan, E., Fothergill, R., Bowler, S., Kordowicz, M., Palastanga, N., Wilkins, L., Spaight, R., Miller, E., & Gordon, A. (2024). Predictors of care home resident conveyance to hospital or referral to community pathways by a regional ambulance service attending medical emergencies: a retrospective cross sectional study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 32(1), Article 121. https://doi.org/10.1186/s13049-024-01294-y

Background
Care home residents are at higher risk compared with community dwelling elders for medical emergencies, often resulting in ambulance attendance and conveyance to hospital. We aimed to determine the factors predicting care home resident co... Read More about Predictors of care home resident conveyance to hospital or referral to community pathways by a regional ambulance service attending medical emergencies: a retrospective cross sectional study.

Cohort Profile: The Xiangya Osteoarthritis (XO) Study (2024)
Journal Article
Li, J., Yang, T., Zhang, Y., Zhang, W., Doherty, M., Xie, J., Wang, Y., Jiang, T., Xie, D., Li, H., Yang, Z., Li, X., Li, W., Xu, B., Zhu, Z., Wang, Y., Weng, Q., Liu, K., Yang, Y., Xu, J., …Lei, G. (2024). Cohort Profile: The Xiangya Osteoarthritis (XO) Study. International Journal of Epidemiology, 53(6), Article dyae156. https://doi.org/10.1093/ije/dyae156

Lessons from the PROTECT-CH COVID-19 platform trial in care homes (2024)
Journal Article
Bath, P. M., Ball, J., Boyd, M., Gage, H., Glover, M., Godfrey, M., Guthrie, B., Hewitt, J., Howard, R., Jaki, T., Juszczak, E., Lasserson, D., Leighton, P., Leyland, V., Shen Lim, W., Logan, P., Meakin, G., Montgomery, A., Ogollah, R., Passmore, P., …Gordon, A. L. (in press). Lessons from the PROTECT-CH COVID-19 platform trial in care homes. Health Technology Assessment,

How and why do community stakeholders participate in the national stroke audit in England? Findings from a mixed-method online survey (2024)
Journal Article
Russell, L., Chouliara, N., Lewis, S., James, M., & Fisher, R. (2024). How and why do community stakeholders participate in the national stroke audit in England? Findings from a mixed-method online survey. BMC Health Services Research, 24(1), Article 1358. https://doi.org/10.1186/s12913-024-11653-1

Background: National audit programmes are a recognised means of assessing quality of healthcare by collecting and reporting data in relation to evidence-based standards. The Sentinel Stroke National Audit Programme is a prospective audit of processes... Read More about How and why do community stakeholders participate in the national stroke audit in England? Findings from a mixed-method online survey.

Associations between biomarkers and skeletal muscle function in individuals with osteoarthritis: a systematic review and meta-analysis (2024)
Journal Article
Smith, S. L., Paul, L., Steultjens, M. P. M., & Jones, R. L. (2024). Associations between biomarkers and skeletal muscle function in individuals with osteoarthritis: a systematic review and meta-analysis. Arthritis Research and Therapy, 26, Article 189. https://doi.org/10.1186/s13075-024-03419-1

Objectives: Skeletal muscle dysfunction is the primary cause of functional limitations in osteoarthritis, associated biomarkers have the potential as targets for early disease identification, diagnosis, and prevention of osteoarthritis disability. Th... Read More about Associations between biomarkers and skeletal muscle function in individuals with osteoarthritis: a systematic review and meta-analysis.

Communities of Practice (CoP) - a public health tool for facilitating implementation of research into practice for a falls prevention exercise intervention; an ethnographic study (2024)
Preprint / Working Paper
Orton, E., Alderman, V., Carpenter, H., Coupland, C., Gladman, J., Iliffe, S., Kendrick, D., Lafond, N., Logan, P., Okereke, U., Skelton, D., Masud, T., & Timmons, S. (2024). Communities of Practice (CoP) - a public health tool for facilitating implementation of research into practice for a falls prevention exercise intervention; an ethnographic study

Introduction
In public health there is often a disconnect in translating research into practice.
The Falls Management Exercise (FaME) programme is an evidence-based exercise programme aimed at reducing falls in older adults. Whilst recommended as... Read More about Communities of Practice (CoP) - a public health tool for facilitating implementation of research into practice for a falls prevention exercise intervention; an ethnographic study.

Gut Microbiome Diversity and Composition Correlates With Time in the Therapeutic Range in Patients on Warfarin Treatment: A Pilot Study (2024)
Journal Article
Agosti, P., Kouraki, A., Dionisi, T., Addolorato, G., D’Innocenzo, L., Sorrentino, S., De Maio, F., De Candia, E., Blanco-Miguez, A., Bazzani, D., Bonadiman, A., Tonidandel, G., Bolzan, M., Gianniello, F., Passamonti, S. M., Abbattista, M., Valdes, A. M., Bucciarelli, P., Peyvandi, F., & Menni, C. (2024). Gut Microbiome Diversity and Composition Correlates With Time in the Therapeutic Range in Patients on Warfarin Treatment: A Pilot Study. Arteriosclerosis, Thrombosis, and Vascular Biology, https://doi.org/10.1161/ATVBAHA.124.321490

PRevention Intervention and Support in Mental health for people with aphasia (Aphasia PRISM): protocol and mixed methods analysis plan for two feasibility studies (2024)
Journal Article
Baker, C., Rose, M. L., Wong, D., Ryan, B., Thomas, S., Cadilhac, D., & Kneebone, I. (in press). PRevention Intervention and Support in Mental health for people with aphasia (Aphasia PRISM): protocol and mixed methods analysis plan for two feasibility studies. Discover Psychology, 4(1), Article 153. https://doi.org/10.1007/s44202-024-00210-w

Background People with aphasia commonly experience depression and anxiety. The individual therapy program, Aphasia PRevention Intervention and Support in Mental health (Aphasia PRISM) offers low intensity psychotherapeutic interventions using communi... Read More about PRevention Intervention and Support in Mental health for people with aphasia (Aphasia PRISM): protocol and mixed methods analysis plan for two feasibility studies.

FreshLanDiv: A Global Database of Freshwater Biodiversity Across Different Land Uses (2024)
Journal Article
Shen, M., van Klink, R., Sagouis, A., Petsch, D. K., Abong'o, D. A., Alahuhta, J., Al‐Shami, S. A., Armendáriz, L. C., Bae, M., Begot, T. O., Belliard, J., Benstead, J. P., Bomfim, F. F., Bredenhand, E., Budnick, W. R., Callisto, M., Calvão, L. B., Camacho‐Rozo, C. P., Cañedo‐Argüelles, M., Carvalho, F. G., …Chase, J. M. (2024). FreshLanDiv: A Global Database of Freshwater Biodiversity Across Different Land Uses. Global Ecology and Biogeography, 33(12), Article e13917. https://doi.org/10.1111/geb.13917

Motivation
Freshwater ecosystems have been heavily impacted by land-use changes, but data syntheses on these impacts are still limited. Here, we compiled a global database encompassing 241 studies with species abundance data (from multiple biologica... Read More about FreshLanDiv: A Global Database of Freshwater Biodiversity Across Different Land Uses.

Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study (2024)
Journal Article
De Dios Perez, B., Holmes, J., Elder, T., Lindley, R., Evangelou, N., das Nair, R., Senior, C., Booth, V., Hassard, J., Ford, H. L., Newsome, I., & Radford, K. (2024). Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2024.2417031

Purpose: To implement a job retention vocational rehabilitation (VR) intervention (MSVR) for people with multiple sclerosis (MS) and their employers in the UK National Health Service (NHS). Methods: Multicentre, single-arm feasibility study with post... Read More about Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study.