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All Outputs (434)

A refresh of the top 10 research priorities in cystic fibrosis (2023)
Journal Article
Rowbotham, N. J., Smith, S., Elliott, Z. C., Cupid, B., Allen, L. J., Cowan, K., …Smyth, A. R. (2023). A refresh of the top 10 research priorities in cystic fibrosis. Thorax, 78(8), 840-843. https://doi.org/10.1136/thorax-2023-220100

In 2018 we published the James Lind Alliance (JLA) top 10 priorities for clinical research in cystic fibrosis (CF), chosen jointly by the patient and clinical communities. These priorities have led to new research funding. To establish whether priori... Read More about A refresh of the top 10 research priorities in cystic fibrosis.

Comparison of the effectiveness of exclusively facilitated clinical teaching as an alternative to traditional practice-based primary care placements (2023)
Journal Article
Tyrrell, E. G., Knox, R., Saha, R., Berry, K., & Taggar, J. S. (2023). Comparison of the effectiveness of exclusively facilitated clinical teaching as an alternative to traditional practice-based primary care placements. Education for Primary Care, 34(3), 152-160. https://doi.org/10.1080/14739879.2023.2217795

Introduction: COVID-19 presented major challenges to undergraduate GP placement capacity and there was an increased reliance on clinical training using facilitated simulation. The authors present a novel comparison of the effectiveness and cost-effec... Read More about Comparison of the effectiveness of exclusively facilitated clinical teaching as an alternative to traditional practice-based primary care placements.

Care for older forensic mental health patients: A consensus guidance document (2023)
Journal Article
Tomlin, J., Walker, K., Yates, J., Dening, T., Goethals, K., Völlm, B., & Griffiths, C. (2023). Care for older forensic mental health patients: A consensus guidance document. European Psychiatry, 66(1), Article e44. https://doi.org/10.1192/j.eurpsy.2023.2413

Background
It is important to investigate the needs, experiences, and outcomes of older forensic mental health inpatients. In this consensus document, we offer practitioners working with older forensic inpatients recommendations to meet the unique o... Read More about Care for older forensic mental health patients: A consensus guidance document.

Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university (2023)
Journal Article
Fairbanks, E. L., Bolton, K. J., Jia, R., Figueredo, G. P., Knight, H., & Vedhara, K. (2023). Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university. Epidemics, 43, Article 100688. https://doi.org/10.1016/j.epidem.2023.100688

We survey 62 users of a university asymptomatic SARS-CoV-2 testing service on details of their activities, protective behaviours and contacts in the 7 days prior to receiving a positive or negative SARS-CoV-2 PCR test result in the period October 202... Read More about Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university.

Barriers and facilitators to Yoga for obesity, diabetes, and hypertension: a qualitative systematic review protocol (2023)
Journal Article
Chattopadhyay, K., Biswas, I., & Wang, H. (2023). Barriers and facilitators to Yoga for obesity, diabetes, and hypertension: a qualitative systematic review protocol. International Journal of Yoga - Philosophy, Psychology and Parapsychology, 16(2), 148-152. https://doi.org/10.4103/ijoy.ijoy_138_23

The global burden of obesity, diabetes, and hypertension is high and increasing. Several systematic reviews suggest Yoga, an ancient mind-body discipline from the Indian subcontinent, is safe and can be beneficial for preventing and managing obesity,... Read More about Barriers and facilitators to Yoga for obesity, diabetes, and hypertension: a qualitative systematic review protocol.

1-year survival in haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003–2018 (2023)
Journal Article
West, J., Stilwell, P., Liu, H., Ban, L., Bythell, M., Card, T., …Crooks, C. (2023). 1-year survival in haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003–2018. Journal of Hematology and Oncology, 16, Article 56. https://doi.org/10.1186/s13045-023-01434-4

Haemophagocytic lymphohistiocytosis (HLH) is a lethal syndrome of excessive immune activation. We undertook a nationwide study in England of all cases of HLH diagnosed between 2003 and 2018, using linked electronic health data from hospital admission... Read More about 1-year survival in haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003–2018.

Implementation of a diabetes prevention programme in a multi-ethnic community in primary care in England: An evaluation using constructs from the RE-AIM Framework (2023)
Journal Article
Dallosso, H., Khunti, K., Gray, L. J., Hulley, K., Ghaly, M., Patel, N., …Yates, T. (2023). Implementation of a diabetes prevention programme in a multi-ethnic community in primary care in England: An evaluation using constructs from the RE-AIM Framework. Primary Care Diabetes, 17(4), 309-313. https://doi.org/10.1016/j.pcd.2023.05.001

Aims: To implement a diabetes prevention programme in primary care Methods: The programme was implemented for 12 months in two neighbouring towns, served by eight general practices. Practices requested a referral pathway involving an external adminis... Read More about Implementation of a diabetes prevention programme in a multi-ethnic community in primary care in England: An evaluation using constructs from the RE-AIM Framework.

Correction to: Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People in India: A Multicenter Feasibility Randomized Controlled Trial (2023)
Journal Article
Chattopadhyay, K., Mishra, P., Singh, K., Singh, K., Harris, T., Hamer, M., …YOGA-DP Study Team. (2023). Correction to: Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People in India: A Multicenter Feasibility Randomized Controlled Trial. Diabetes Therapy, 14, 1155–1156. https://doi.org/10.1007/s13300-023-01420-6

The "YOGA-DP Study Team" has been added to the author group in the article PDF. The original article has been corrected.

Self-collected versus health-care professional taken swab for identification of vaginal-rectal colonisation with group B streptococcus in late pregnancy: a systematic review (2023)
Journal Article
Odubamowo, K., Garcia, M., Muriithi, F., Ogollah, R., Daniels, J. P., & Walker, K. F. (2023). Self-collected versus health-care professional taken swab for identification of vaginal-rectal colonisation with group B streptococcus in late pregnancy: a systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 286, 95-101. https://doi.org/10.1016/j.ejogrb.2023.05.027

Background
Testing for group B streptococcus (GBS) requires a vaginal-rectal swab in late pregnancy.
Objective
A systematic review of the test accuracy of a self-collected swab compared with a health-care professional collected swab in the diagnos... Read More about Self-collected versus health-care professional taken swab for identification of vaginal-rectal colonisation with group B streptococcus in late pregnancy: a systematic review.

The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study (2023)
Preprint / Working Paper
Swiderski, M., Vinogradova, Y., Knaggs, R., Harman, K., Harwood, R., Prasad, V., …Gran, S. The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study

Introduction
Bullous pemphigoid (BP) is a serious skin disease that results in large painful blisters developing over the body and occurs most commonly in older people (over 70 years). Despite several comorbidities such as stroke and a threefold inc... Read More about The association between prescription drugs and vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study.

Anaemia of acute inflammation: a higher acute systemic inflammatory response is associated with a larger decrease in blood haemoglobin levels in patients with COVID-19 infection (2023)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Anaemia of acute inflammation: a higher acute systemic inflammatory response is associated with a larger decrease in blood haemoglobin levels in patients with COVID-19 infection. Clinical Medicine, 23(3), 201-205. https://doi.org/10.7861/clinmed.2022-0436

AIMS: The study tests the hypothesis that a higher acute systemic inflammatory response was associated with a larger decrease in blood hemoglobin levels in patients with Coronavirus 2019 (COVID-19) infection. METHODS: All patients with either suspect... Read More about Anaemia of acute inflammation: a higher acute systemic inflammatory response is associated with a larger decrease in blood haemoglobin levels in patients with COVID-19 infection.

Evaluating the effect of weekly patient-reported symptom monitoring on trial outcomes: results of the Eczema Monitoring Online randomised controlled trial (2023)
Journal Article
Baker, A., Mitchell, E. J., Partlett, C., & Thomas, K. S. (2023). Evaluating the effect of weekly patient-reported symptom monitoring on trial outcomes: results of the Eczema Monitoring Online randomised controlled trial. British Journal of Dermatology, 189(2), 180–187. https://doi.org/10.1093/bjd/ljad163

BACKGROUND: Patient-reported outcome measures (PROMs) are commonly used in eczema clinical trials. Several trials have used PROMs weekly for symptom monitoring. However, the increased frequency of patient-reported symptom monitoring may prompt partic... Read More about Evaluating the effect of weekly patient-reported symptom monitoring on trial outcomes: results of the Eczema Monitoring Online randomised controlled trial.

Patient safety in prisons: a multi-method analysis of reported incidents in England (2023)
Journal Article
McFadzean, I. J., Davies, K., Purchase, T., Edwards, A., Hellard, S., Ashcroft, D. M., …Carson-Stevens, A. (2023). Patient safety in prisons: a multi-method analysis of reported incidents in England. Journal of the Royal Society of Medicine, 116(7), 236-245. https://doi.org/10.1177/01410768231166138

Objectives
Prisoners use healthcare services three times more frequently than the general population with poorer health outcomes. Their distinct healthcare needs often pose challenges to safe healthcare provision. This study aimed to characterise pa... Read More about Patient safety in prisons: a multi-method analysis of reported incidents in England.

Parental experiences of eczema advice in online parenting forums: a qualitative interview study (2023)
Journal Article
Treadgold, B. M., Muller, I., Teasdale, E., Coulson, N., Roberts, A., & Santer, M. (2023). Parental experiences of eczema advice in online parenting forums: a qualitative interview study. BJGP Open, 7(2), Article BJGPO.2022.0155. https://doi.org/10.3399/bjgpo.2022.0155

Background: Parents of children with eczema are increasingly turning to online parenting forums for advice about how to manage it. Little is known about how parents make sense of advice about eczema treatments in online forums, and how it affects the... Read More about Parental experiences of eczema advice in online parenting forums: a qualitative interview study.

The Classification of Movement in Infants for the Autonomous Monitoring of Neurological Development (2023)
Journal Article
Turner, A., Hayes, S., & Sharkey, D. (2023). The Classification of Movement in Infants for the Autonomous Monitoring of Neurological Development. Sensors, 23(10), Article 4800. https://doi.org/10.3390/s23104800

Neurodevelopmental delay following extremely preterm birth or birth asphyxia is common but diagnosis is often delayed as early milder signs are not recognised by parents or clinicians. Early interventions have been shown to improve outcomes. Automati... Read More about The Classification of Movement in Infants for the Autonomous Monitoring of Neurological Development.

Delivering yoga to people with hypertension in the UK: A qualitative study to explore yoga providers' knowledge, experiences, and attitudes (2023)
Journal Article
Nalbant, G., Hassanein, Z. M., Lewis, S., & Chattopadhyay, K. (2023). Delivering yoga to people with hypertension in the UK: A qualitative study to explore yoga providers' knowledge, experiences, and attitudes. Health Science Reports, 6(5), Article 1260. https://doi.org/10.1002/hsr2.1260

Background and Aims: Yoga has become increasingly popular in the world and the UK for improving health and well‐being. A growing body of research suggests that yoga could be used to improve the management of hypertension in addition to current manage... Read More about Delivering yoga to people with hypertension in the UK: A qualitative study to explore yoga providers' knowledge, experiences, and attitudes.

‘It’s just a finger isn’t it…’: patients’ perspectives of recovery following finger fractures and participation in surgical trials – a qualitative interview study (2023)
Journal Article
Mousoulis, C., Karantana, A., Trickett, R. W., Thomas, K. S., & Leighton, P. (2023). ‘It’s just a finger isn’t it…’: patients’ perspectives of recovery following finger fractures and participation in surgical trials – a qualitative interview study. BMJ Open, 13(5), Article e065185. https://doi.org/10.1136/bmjopen-2022-065185

Objectives: To (1) generate detailed, person-centred data about the experience of finger injury and treatment and (2) understand the patients’ perspectives of research involvement with a view to informing better designed future studies in hand injury... Read More about ‘It’s just a finger isn’t it…’: patients’ perspectives of recovery following finger fractures and participation in surgical trials – a qualitative interview study.

A modelling approach to studying variations in newborn life support procedure (2023)
Journal Article
Tan, A., Remenyte-Prescott, R., Valstar, M., & Sharkey, D. (2024). A modelling approach to studying variations in newborn life support procedure. Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability, 238(4), 777-796. https://doi.org/10.1177/1748006X231173595

Variations in clinical practice are common. However, some variations may cause undesired consequences. Careful consideration of their causes and effects is necessary to assure the quality of healthcare delivery. A modelling approach that could captur... Read More about A modelling approach to studying variations in newborn life support procedure.

Disparities in care and outcomes for primary liver cancer in England during 2008–2018: a cohort study of 8.52 million primary care population using the QResearch database (2023)
Journal Article
Liao, W., Coupland, C. A., Innes, H., Jepsen, P., Matthews, P. C., Campbell, C., …Welberry, C. (2023). Disparities in care and outcomes for primary liver cancer in England during 2008–2018: a cohort study of 8.52 million primary care population using the QResearch database. eClinicalMedicine, 59, Article 101969. https://doi.org/10.1016/j.eclinm.2023.101969

Background: Liver cancer has one of the fastest rising incidence and mortality rates among all cancers in the UK, but it receives little attention. This study aims to understand the disparities in epidemiology and clinical pathways of primary liver c... Read More about Disparities in care and outcomes for primary liver cancer in England during 2008–2018: a cohort study of 8.52 million primary care population using the QResearch database.

Women’s knowledge of and attitudes towards group B streptococcus (GBS) testing in pregnancy: a qualitative study (2023)
Journal Article
Constantinou, G., Ayers, S., Mitchell, E. J., Walker, K. F., Daniels, J., Moore, S., …Downe, S. (2023). Women’s knowledge of and attitudes towards group B streptococcus (GBS) testing in pregnancy: a qualitative study. BMC Pregnancy and Childbirth, 23, Article 339. https://doi.org/10.1186/s12884-023-05651-0

Background: 20–25% pregnant women in the UK carry group B streptococcus (GBS) which, if left undetected, is transmitted from pregnant mothers to their babies during birth in 36% of cases. This transmission leads to early onset GBS infection (EOGBS) i... Read More about Women’s knowledge of and attitudes towards group B streptococcus (GBS) testing in pregnancy: a qualitative study.