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Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study (2023)
Journal Article
Holden, M. A., Hawarden, A., Paskins, Z., Roddy, E., Mallen, C. D., Liddle, J., …Jinks, C. (2023). Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study. Musculoskeletal Care, 21(4), 1601-1611. https://doi.org/10.1002/msc.1830

Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic or local anaesthetic alone to advice and education among people with hi... Read More about Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study.

Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study (2023)
Journal Article
Szatkowski, L., Sharkey, D., Budge, H., & Ojha, S. (2023). Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study. eClinicalMedicine, 65, Article 102296. https://doi.org/10.1016/j.eclinm.2023.102296

Background: Preterm infants often require mechanical ventilation (MV), which can be a painful experience. Opioids (such as morphine) are used to provide analgesia, despite conflicting evidence about their impact on the developing brain. We aimed to q... Read More about Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study.

Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care (2023)
Journal Article
Bailey, J. A., Morton, A. J., Jones, J., Chapman, C. J., Oliver, S., Morling, J. R., …Humes, D. J. (2023). Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care. British Journal of General Practice, 73(736), e843-e849. https://doi.org/10.3399/bjgp.2023.0033

Background: Faecal Immunochemical Testing (FIT) usage for symptomatic patients is increasing, but variations in use by sociodemographics are unknown. We introduced FIT for symptomatic patients in November 2017. Aim: Identify whether demographics, eth... Read More about Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care.

Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study (2023)
Journal Article
Thompson, W., Swain, S., Zhao, S. S., Kamps, A., Coupland, C., Kuo, C., …Zhang, W. (2023). Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study. Osteoarthritis and Cartilage Open, 5(4), Article 100414. https://doi.org/10.1016/j.ocarto.2023.100414

Objective To investigate the causal association between Osteoarthritis (OA) and five comorbidities: depression, tiredness, multisite chronic pain, irritable bowel syndrome (IBS) and gout.... Read More about Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study.

Migrants’ living conditions, perceived health needs and implications for the use of antibiotics and antimicrobial resistance in the United Kingdom: a qualitative study (2023)
Journal Article
Nanakali, S. S., Hassan, O., Silva, L., Al-Oraibi, A., Chaloner, J., Gogoi, M., …Nellums, L. B. (2023). Migrants’ living conditions, perceived health needs and implications for the use of antibiotics and antimicrobial resistance in the United Kingdom: a qualitative study. Health Science Reports, 6(10), Article e1655. https://doi.org/10.1002/hsr2.1655

Background and Aims: Antimicrobial resistance (AMR) is among the top public health concerns around the globe. Migrants, especially forced migrants, could be at higher risk of acquiring and transmitting AMR during their journeys or in host countries.... Read More about Migrants’ living conditions, perceived health needs and implications for the use of antibiotics and antimicrobial resistance in the United Kingdom: a qualitative study.

Community-based rehabilitation intervention for people with schizophrenia in Ethiopia (RISE) cluster-randomised controlled trial: An exploratory analysis of impact on food insecurity, underweight, alcohol use disorder and depressive symptoms (2023)
Journal Article
Asher, L., Birhane, R., Weiss, H., Medhin, G., Selamu, M., Patel, V., …Fekadu, A. (2023). Community-based rehabilitation intervention for people with schizophrenia in Ethiopia (RISE) cluster-randomised controlled trial: An exploratory analysis of impact on food insecurity, underweight, alcohol use disorder and depressive symptoms. Cambridge Prisms: Global Mental Health, 10, Article E70. https://doi.org/10.1017/gmh.2023.67

We evaluated the effectiveness of community-based rehabilitation (CBR) in reducing depressive symptoms, alcohol use disorder, food insecurity and underweight in people with schizophrenia. This cluster-randomised controlled trial was conducted in a ru... Read More about Community-based rehabilitation intervention for people with schizophrenia in Ethiopia (RISE) cluster-randomised controlled trial: An exploratory analysis of impact on food insecurity, underweight, alcohol use disorder and depressive symptoms.

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis (2023)
Journal Article
Qureshi, N., Woods, B., Neves de Faria, R., Saramago Goncalves, P., Cox, E., Leonardi Bee, J., …Kai, J. (2023). Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis. Health Technology Assessment, 27(16), https://doi.org/10.3310/CTMD0148

Background Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia. The cascade-testing protocol starts with identifying an index patient with familial hyperc... Read More about Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis.

Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT (2023)
Journal Article
Ridd, M. J., Wells, S., MacNeill, S. J., Sanderson, E., Webb, D., Banks, J., …Santer, M. (2023). Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT. Health Technology Assessment, 27(19), 1-120. https://doi.org/10.3310/gzqw6681

Background: Emollients are recommended for children with eczema (atopic eczema/dermatitis). A lack of head-to-head comparisons of the effectiveness and acceptability of the different types of emollients has resulted in a 'trial and error' approach to... Read More about Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT.

Changes in nutrient composition and gene expression in growing mealworms (Tenebrio molitor) (2023)
Journal Article
Lopez-Viso, C., Castellanos-Uribe, M., May, T., Brameld, J., Salter, A., & Parr, T. (2023). Changes in nutrient composition and gene expression in growing mealworms (Tenebrio molitor). Journal of Insects as Food and Feed, 10(4), 601-610. https://doi.org/10.1163/23524588-20230143

Insects are of high interest as a sustainable source of nutrients to be included in the food production system. The larvae of Tenebrio molitor, commonly known as yellow mealworms (MW), have a high protein content, which means potential applications i... Read More about Changes in nutrient composition and gene expression in growing mealworms (Tenebrio molitor).

Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review (2023)
Journal Article
Kalvala, J., Chong, L., Chadborn, N., & Ojha, S. (2023). Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review. BMJ Paediatrics Open, 7(1), Article e002066. https://doi.org/10.1136/bmjpo-2023-002066

Background: Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, br... Read More about Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review.

Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): a prospective cohort study (2023)
Journal Article
Ingram, J. R., Thomas, K. S., Cannings-John, R., Evans, J., Gibbons, A., Howes, R., …Leighton, P. (2024). Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): a prospective cohort study. British Journal of Dermatology, 190(3), 382-391. https://doi.org/10.1093/bjd/ljad388

Background Hidradenitis suppurativa (HS) is a chronic, painful disease affecting flexures and other skin regions, producing nodules, abscesses and skin tunnels. Laser treatment targeting hair follicles and deroofing of skin tunnels are standard HS in... Read More about Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): a prospective cohort study.

Perceptions and Experiences of Undergraduate Students Regarding Social Media as a Tool for Government COVID-19-Related Messages: A Qualitative Study in Nottingham, UK (2023)
Journal Article
Sandhu, S., Wilson, E., & Chattopadhyay, K. (2023). Perceptions and Experiences of Undergraduate Students Regarding Social Media as a Tool for Government COVID-19-Related Messages: A Qualitative Study in Nottingham, UK. International Journal of Environmental Research and Public Health, 20(20), Article 6903. https://doi.org/10.3390/ijerph20206903

The rise of social media has given way to its use as a form of public health communication. Previous research has shown social media-based interventions to be effective, particularly for university students. Social media was used as a tool for public... Read More about Perceptions and Experiences of Undergraduate Students Regarding Social Media as a Tool for Government COVID-19-Related Messages: A Qualitative Study in Nottingham, UK.

Obesity, metabolic health and clinical outcomes after incident cardiovascular disease: A nationwide population-based cohort study (2023)
Journal Article
Akyea, R. K., Ntaios, G., & Doehner, W. (2023). Obesity, metabolic health and clinical outcomes after incident cardiovascular disease: A nationwide population-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 14(6), 2653-2662. https://doi.org/10.1002/jcsm.13340

Background The association between metabolic syndrome and increased cardiovascular disease (CVD) risk is well-established. However, in patients with incident CVD, the relationship between obesity, metabolic health, and subsequent CVD and mortality o... Read More about Obesity, metabolic health and clinical outcomes after incident cardiovascular disease: A nationwide population-based cohort study.

Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study (2023)
Journal Article
Kai, J., Dutton, B., Vinogradova, Y., Hilken, N., Gupta, J., & Daniels, J. (2023). Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study. Health Technology Assessment, 27(17), https://doi.org/10.3310/jhsw0174

Background: Heavy menstrual bleeding is a common problem that can significantly affect women’s lives until menopause. There is a lack of evidence on longer-term outcomes after seeking health care and treatment for heavy menstrual bleeding. Objectives... Read More about Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study.

Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study (2023)
Journal Article
Bishop, S., Narayanasamy, M. J., Paskins, Z., Corp, N., Bastounis, A., Griffin, J., …Sahota, O. (2023). Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study. BMC Musculoskeletal Disorders, 24, Article 770. https://doi.org/10.1186/s12891-023-06865-1

Background Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly tak... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.

Outcomes after emergency appendicectomy in patients with liver cirrhosis: a population-based cohort study from England (2023)
Journal Article
Adiamah, A., Rashid, A., Crooks, C. J., Hammond, J. S., Jepsen, P., West, J., & Humes, D. J. (2023). Outcomes after emergency appendicectomy in patients with liver cirrhosis: a population-based cohort study from England. Langenbeck's Archives of Surgery, 408, Article 362. https://doi.org/10.1007/s00423-023-03072-3

Introduction The mortality risk after appendicectomy in patients with liver cirrhosis is predicted to be higher than in the general population given the associated risk of perioperative bleeding, infections and liver decompensation. This population-... Read More about Outcomes after emergency appendicectomy in patients with liver cirrhosis: a population-based cohort study from England.

A population-based study exploring phenotypic clusters and clinical outcomes in stroke using unsupervised machine learning approach (2023)
Journal Article
Akyea, R. K., Ntaios, G., Kontopantelis, E., Georgiopoulos, G., Soria, D., Asselbergs, F. W., …Qureshi, N. (2023). A population-based study exploring phenotypic clusters and clinical outcomes in stroke using unsupervised machine learning approach. PLOS Digital Health, 2(9), Article e0000334. https://doi.org/10.1371/journal.pdig.0000334

Individuals developing stroke have varying clinical characteristics, demographic, and biochemical profiles. This heterogeneity in phenotypic characteristics can impact on cardiovascular disease (CVD) morbidity and mortality outcomes. This study uses... Read More about A population-based study exploring phenotypic clusters and clinical outcomes in stroke using unsupervised machine learning approach.

Application and Extension of the Alcohol Recovery Narratives Conceptual Framework (2023)
Journal Article
Subhani, M., Talat, U., Knight, H., Morling, J. R., Jones, K. A., Aithal, G. P., …Rennick-Egglestone, S. (2023). Application and Extension of the Alcohol Recovery Narratives Conceptual Framework. Qualitative Health Research, 33(13), 1203-1217. https://doi.org/10.1177/10497323231197384

Recovery narratives are personal stories of health problems and recovery. A systematic review proposed a conceptual framework characterising alcohol misuse recovery narratives, consisting of eight principal dimensions, each with types and subtypes. T... Read More about Application and Extension of the Alcohol Recovery Narratives Conceptual Framework.

Developing evidence-based patient-focused learning materials to support health behaviour change for people living with psoriatic arthritis (2023)
Journal Article
Hailey, L., Howells, L., Bundy, C., Kirtley, S., Martin, S., O'Sullivan, D., …Coates, L. C. (2023). Developing evidence-based patient-focused learning materials to support health behaviour change for people living with psoriatic arthritis. RMD Open, 9(3), Article e003190. https://doi.org/10.1136/rmdopen-2023-003190

Objectives: In psoriatic arthritis (PsA), self-management is important for patient function and quality of life. Behaviour change can be difficult, patients could benefit from high-quality support to initiate change. Our aim was to codesign the proje... Read More about Developing evidence-based patient-focused learning materials to support health behaviour change for people living with psoriatic arthritis.