Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care

Bailey, James A.; Morton, Alastair James; Jones, James; Chapman, Caroline J.; Oliver, Simon; Morling, Joanne R.; Patel, Heetan; Banerjea, Ayan; Humes, David J.

Abstract

Background: Faecal Immunochemical Testing (FIT) usage for symptomatic patients is increasing, but variations in use by sociodemographics are unknown. We introduced FIT for symptomatic patients in November 2017. Aim: Identify whether demographics, ethnicity or social deprivation affect FIT return in symptomatic patients. Design and Setting: FIT was introduced as a triage tool in Primary Care and was mandated for all colorectal referrals (except rectal bleeding/mass) to secondary care. FIT was used, alongside full blood count and ferritin, to stratify colorectal cancer risk. Method: All referrals November 2017-December 2021 were retrospectively reviewed. Sociodemographic factors affecting FIT return were analysed by multivariate logistic regression. Results: 35,289 patients returned their index FIT (90.7%), 3631 (9.3%) did not. On multivariate analysis, males were less likely to return FIT (OR 1.11, 95%CI 1.03-1.19). Patients over 65 were more likely to return FIT (OR 0.78 for non-return, 95%CI 0.72-0.83). Unreturned FIT was more than doubled in the most compared to the least deprived (OR 2.20, 95%CI 1.99-2.43). Patients from Asian (OR 1.82, 95%CI 1.58-2.10), Black (OR 1.21, 95%CI 0.98-1.49) and Mixed/Other ethnic groups (OR 1.29, 95%CI 1.05-1.59) were more likely to not return FIT compared to White ethnicity. 599 colorectal cancers were detected (1.5%), 561 in those who returned a first FIT request, 38 in those who did not. Conclusion: FIT return in those suspected of having colorectal cancer varies by gender, age, ethnicity, and socioeconomic deprivation. Strategies to mitigate effects on FIT return and colorectal cancer detection should be considered as FIT usage expands.

• Journal Article Type: Article
• Acceptance Date: May 16, 2023
• Online Publication Date: Oct 26, 2023
• Publication Date: Oct 26, 2023
• Deposit Date: Sep 6, 2023
• Publicly Available Date: Sep 12, 2023
• Journal: British Journal of General Practice
• Print ISSN: 0960-1643
• Electronic ISSN: 1478-5242
• Publisher: Royal College of General Practitioners
• Peer Reviewed: Peer Reviewed
• Volume: 73
• Issue: 736
• Pages: e843-e849
• DOI: https://doi.org/10.3399/bjgp.2023.0033
• Keywords: Colorectal Cancer; Faecal Immunochemical Testing; Inequality; Social Deprivation
• Public URL: https://nottingham-repository.worktribe.com/output/24585790
• Publisher URL: https://bjgp.org/content/early/2023/08/31/BJGP.2023.0033