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All Outputs (336)

Supporting early‐career dementia researchers: Identifying support needs and ways forward via a European study (2023)
Journal Article
Dupont, C., Gilissen, J., Dassen, F. C. M., Branco, R. M., Heins, P., Heffernan, E., & Bartels, S. L. (2024). Supporting early‐career dementia researchers: Identifying support needs and ways forward via a European study. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(2), 1321-1333. https://doi.org/10.1002/alz.13530

INTRODUCTION Early-career researchers contribute significantly to dementia research and clinical practice. However, a growing group of early-career dementia researchers (ECDRs) lack appropriate support throughout their careers. Thus, we aim to (i) e... Read More about Supporting early‐career dementia researchers: Identifying support needs and ways forward via a European study.

A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches (2023)
Journal Article
Warrington, S., Ntata, A., Mougin, O., Campbell, J., Torchi, A., Craig, M., …Sotiropoulos, S. N. (2023). A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches. Imaging Neuroscience, 1(2023), 1-27. https://doi.org/10.1162/imag_a_00042

Despite the huge potential of magnetic resonance imaging (MRI) in mapping and exploring the brain, MRI measures can often be limited in their consistency, reproducibility and accuracy which subsequently restricts their quantifiability. Nuisance nonbi... Read More about A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches.

BASIL: A Toolbox for Perfusion Quantification using Arterial Spin Labelling (2023)
Journal Article
Chappell, M. A., Kirk, T. F., Craig, M. S., McConnell, F. A. K., Zhao, M. Y., MacIntosh, B. J., …Woolrich, M. W. (2023). BASIL: A Toolbox for Perfusion Quantification using Arterial Spin Labelling. Imaging Neuroscience, https://doi.org/10.1162/imag_a_00041

Arterial Spin Labelling (ASL) MRI is now an established non-invasive method to quantify cerebral blood flow and is increasingly being used in a variety of neuroimaging applications. With standard ASL acquisition protocols widely available, there is a... Read More about BASIL: A Toolbox for Perfusion Quantification using Arterial Spin Labelling.

Transforming Workplace Learning: Implementing Mental Health First Aid Programmes at Work (2023)
Presentation / Conference Contribution
Dulal-Arthur, T., Siddiqui, M., Vaughan, B., Thomson, L., Bartle, C., Hassard, J., & Blake, H. (2023). Transforming Workplace Learning: Implementing Mental Health First Aid Programmes at Work. In ICERI2023 Proceedings. https://doi.org/10.21125/iceri.2023.1317

Traditional conceptualisations of workplace learning focus on enhancing professional skills and knowledge related to job performance. However, considering the increased prevalence and impact of mental health challenges in the workplace, it is imperat... Read More about Transforming Workplace Learning: Implementing Mental Health First Aid Programmes at Work.

Navigating the Path to Success: Exploring methods to integrate workforce digital training within organisations (2023)
Presentation / Conference Contribution
Siddiqui, M., Dulal-Arthur, T., Vaughan, B., Thomson, L., Bartle, C., Hassard, J., & Blake, H. (2023). Navigating the Path to Success: Exploring methods to integrate workforce digital training within organisations. In ICERI2023 Proceedings. https://doi.org/10.21125/iceri.2023.1183

With the proliferation of e-learning in the workplace, organisations demand new ways to transform the employee's learning experience, maintain engagement with learning and ensure that it is sustained into continuing growth and development. Ensuring t... Read More about Navigating the Path to Success: Exploring methods to integrate workforce digital training within organisations.

Relationship between self-reported listening and communication difficulties and executive function: a protocol for a systematic review and meta-analysis (2023)
Journal Article
Stacey, J. E., Danielsson, H., Heinrich, A., Batinović, L., Holmer, E., Ingo, E., & Henshaw, H. (2023). Relationship between self-reported listening and communication difficulties and executive function: a protocol for a systematic review and meta-analysis. BMJ Open, 13(11), Article e071225. https://doi.org/10.1136/bmjopen-2022-071225

Introduction: Listening and communication difficulties can limit people’s participation in activity and adversely affect their quality of life. Hearing, as well as listening and communication difficulties, can be measured either by using behavioural... Read More about Relationship between self-reported listening and communication difficulties and executive function: a protocol for a systematic review and meta-analysis.

When Hearing Loss Co-occurs with Dementia: Challenges and Opportunities in Diagnosis and Management (2023)
Book Chapter
Broome, E., Burgon, C., Heffernan, E., Dening, T., Calvert, S., Rajasingam, S., & Henshaw, H. (2023). When Hearing Loss Co-occurs with Dementia: Challenges and Opportunities in Diagnosis and Management. In A. Ciorba, & S. Hatzopoulos (Eds.), Updates on Hearing Loss and its Rehabilitation (1-27). InTech. https://doi.org/10.5772/intechopen.1003179

Both dementia and hearing loss are highly prevalent in older adults and often coexist, increasing the complexity of diagnosis and management of both conditions. As the population ages, an increasing number of people will experience both long-term con... Read More about When Hearing Loss Co-occurs with Dementia: Challenges and Opportunities in Diagnosis and Management.

An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs (2023)
Journal Article
Chow, R. T., Whiting, D., Favril, L., Ostinelli, E., Cipriani, A., & Fazel, S. (2023). An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs. Neuroscience and Biobehavioral Reviews, 155, Article 105454. https://doi.org/10.1016/j.neubiorev.2023.105454

Antipsychotic medications are widely prescribed in psychotic illnesses and other mental disorders. Effectiveness is well-established, particularly for reducing symptoms such as delusions and hallucinations, but can be impacted by tolerability. Advers... Read More about An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs.

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data (2023)
Journal Article
Jack, R. H., Joseph, R. M., Hollis, C., Hippisley-Cox, J., Butler, D., Waldram, D., & Coupland, C. (2023). Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data. BMJ Mental Health, 26(1), Article e300855. https://doi.org/10.1136/bmjment-2023-300855

Background There is an increasing demand for mental health services for young people, which may vary across the year. Objective To determine whether there are seasonal patterns in primary care antidepressant prescribing and mental health issues in... Read More about Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data.

Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study (2023)
Journal Article
Prasad, V., Rezel-Potts, E., White, P., Downs, J., Boddy, N., Sayal, K., & Sonuga-Barke, E. (2024). Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study. Archives of Disease in Childhood, 109, Article 46-51. https://doi.org/10.1136/archdischild-2023-325637

Objective: To compare use of healthcare services and reasons for attendance by children and young people (CYP) with attention-deficit/hyperactivity disorder (ADHD) versus non-ADHD controls. Design: Population-based matched case-control study. Setting... Read More about Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study.

A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis. (2023)
Journal Article
Chen, K., Weng, Y., Hosseini, A. A., Dening, T., Zuo, G., & Zhang, Y. (2024). A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis. Neural Networks, 169, 442-452. https://doi.org/10.1016/j.neunet.2023.10.040

Alzheimer’s Disease (AD) is a neurodegenerative disease that commonly occurs in older people. It is characterized by both cognitive and functional impairment. However, as AD has an unclear pathological cause, it can be hard to diagnose with confidenc... Read More about A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis..

Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis (2023)
Journal Article
Gosling, C. J., & Sayal, K. (2023). Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis. Lancet Psychiatry, 10(12), 922-933. https://doi.org/10.1016/S2215-0366%2823%2900272-9

Background: The youngest children in a school class are more likely than the oldest to be diagnosed with ADHD, but this relative age effect is less frequent in older than in younger school-grade children. However, no study has explored the associatio... Read More about Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis.

Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial (2023)
Journal Article
Thomson, L., Hassard, J., Frost, A., Bartle, C., Yarker, J., Munir, F., …Blake, H. (2023). Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial. JMIR Research Protocols, 12, Article e48758. https://doi.org/10.2196/48758

Background: Mental health problems affect 1 in 6 workers annually and are one of the leading causes of sickness absence, with stress, anxiety, and depression being responsible for half of all working days lost in the United Kingdom. Primary intervent... Read More about Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial.

Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage (2023)
Journal Article
Eilertsen, H., Menon, C. S., Law, Z. K., Chen, C., Bath, P. M., Steiner, T., …Al-Shahi Salman, R. (2023). Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage. Cochrane Database of Systematic Reviews, 2023(10), Article CD005951.pub5. https://doi.org/10.1002/14651858.CD005951.pub5

Background Outcome after acute spontaneous (non‐traumatic) intracerebral haemorrhage (ICH) is influenced by haematoma volume. ICH expansion occurs in about 20% of people with acute ICH. Early haemostatic therapy might improve outcome by limiting ICH... Read More about Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage.

Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research (2023)
Journal Article
MacDonald, C., Caimino, C., Burns-O’Connell, G., Hartley, D., Lockwood, J., Sereda, M., …J. Hoare, D. (2023). Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research. Brain Sciences, 13(10), Article 1496. https://doi.org/10.3390/brainsci13101496

Tinnitus (the perception of sound in the absence of any corresponding external source) is highly prevalent and can be distressing. There are unanswered questions about how tinnitus, suicidal thoughts, and suicidal behaviours co-occur and interact. To... Read More about Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research.

Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months (2023)
Journal Article
Nixon, N., Guo, B., Kaylor-Hughes, C., Simpson, S., Garland, A., Dalgleish, T., & Morriss, R. (2024). Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months. Journal of Affective Disorders, 345, 70-77. https://doi.org/10.1016/j.jad.2023.10.105

Background: Despite the known health costs of persistent depression, there is no established service framework for the treatment of this disorder and a lack of long-term outcome data to inform commissioning. To address this gap, we report the long-te... Read More about Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task (2023)
Journal Article
Alfandari, D., Richter, M., Wendt, D., Fiedler, L., & Naylor, G. (2023). Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task. Trends in Hearing, 27, Article 23312165231196520. https://doi.org/10.1177/23312165231196520

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task (2023)
Journal Article
Alfandari, D., Richter, M., Wendt, D., Fiedler, L., & Naylor, G. (2023). Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task. Trends in Hearing, Article 27. https://doi.org/10.1177/23312165231196520

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task.

Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist (2023)
Presentation / Conference Contribution
Christie, H. L., Atefi, G. L., Craven, M. P., Orrell, M., & de Vugt, M. E. (2023, October). Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist. Poster presented at 33rd Alzheimer Europe Conference, Helsinki, Finland

Situation: eHealth interventions are a possible solution for rising dementia care costs and potential negative effects on carers Problem: Few evidence-based eHealth interventions are implemented in practice Solution : Adapt existing implementa... Read More about Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist.