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All Outputs (409)

Pathways between digital activity and depressed mood in adolescence: outlining a developmental model integrating risk, reactivity, resilience and reciprocity (2024)
Journal Article
Sonuga-Barke, E. J., Stoilova, M., Kostyrka-Allchorne, K., Bourgaize, J., Murray, A., Tan, M. P., Hollis, C., Townsend, E., & Livingstone, S. (2024). Pathways between digital activity and depressed mood in adolescence: outlining a developmental model integrating risk, reactivity, resilience and reciprocity. Current Opinion in Behavioral Sciences, 58, Article 101411. https://doi.org/10.1016/j.cobeha.2024.101411

Digital technology use (i.e. digital activity) has been proposed to contribute to a decline in adolescents’ mental health. We present a new model of how risky digital activity may increase depressed mood via reciprocal pathways, cre... Read More about Pathways between digital activity and depressed mood in adolescence: outlining a developmental model integrating risk, reactivity, resilience and reciprocity.

Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review (2024)
Journal Article
Kontou, E., Shokraneh, F., das Nair, R., Quinn, T., Leonardi-Bee, J., Thorpe, N., …Drummond, A. (2024). Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review. F1000Research, 13, 1-15. https://doi.org/10.12688/f1000research.146343.2

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, pu... Read More about Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review.

An alternative theoretical approach to develop a new conception about pain in people with dementia (2024)
Journal Article
Morgner, C., Dening, K. H., Dening, T., & Gibson, B. (2024). An alternative theoretical approach to develop a new conception about pain in people with dementia. Medical Humanities, 50(3), 545-554. https://doi.org/10.1136/medhum-2023-012718

The theoretical approach presented in this paper describes a novel experimental-theoretical methodology to conceptualise pain in people with dementia. Existing procedures for assessment of pain rely on subjective self-report using pain questionnaires... Read More about An alternative theoretical approach to develop a new conception about pain in people with dementia.

The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial (2024)
Journal Article
Hollingworth, M., Woodhouse, L. J., Law, Z. K., Ali, A., Krishnan, K., Dineen, R. A., Christensen, H., England, T. J., Roffe, C., Werring, D., Peters, N., Ciccone, A., Robinson, T., Członkowska, A., Bereczki, D., Egea-Guerrero, J. J., Ozturk, S., Bath, P. M., & Sprigg, N. (2024). The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial. Neurosurgery, 95(3), 605-616. https://doi.org/10.1227/neu.0000000000002961

BACKGROUND AND OBJECTIVES:
An important proportion of patients with spontaneous intracerebral hemorrhage (ICH) undergo neurosurgical intervention to reduce mass effect from large hematomas and control the complications of bleeding, including hemato... Read More about The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial.

Dynamical and individualised approach of transcranial ultrasound neuromodulation effects in non-human primates (2024)
Journal Article
Atkinson-Clement, C., Alkhawashki, M., Ross, J., Gatica, M., Zhang, C., Sallet, J., & Kaiser, M. (2024). Dynamical and individualised approach of transcranial ultrasound neuromodulation effects in non-human primates. Scientific Reports, 14, Article 11916. https://doi.org/10.1038/s41598-024-62562-6

Low-frequency transcranial ultrasound stimulation (TUS) allows to alter brain functioning with a high spatial resolution and to reach deep targets. However, the time-course of TUS effects remains largely unknown. We applied TUS on three brain targets... Read More about Dynamical and individualised approach of transcranial ultrasound neuromodulation effects in non-human primates.

Impact of NICE technology appraisal guidance TA566 on access to cochlear implantation for children using hearing aids in the United Kingdom: a multisite observational study (2024)
Journal Article
Killan, C. F., Hoare, D. J., Hartley, D. E., Church, P., Isherwood, F., Nasim, S., …Kitterick, P. T. (2024). Impact of NICE technology appraisal guidance TA566 on access to cochlear implantation for children using hearing aids in the United Kingdom: a multisite observational study. Archives of Disease in Childhood, 109(8), 690-691. https://doi.org/10.1136/archdischild-2023-326055

The impacts associated with having ADHD: an umbrella review (2024)
Journal Article
French, B., Nalbant, G., Wright, H., Sayal, K., Daley, D., Groom, M. J., …Hall, C. L. (2024). The impacts associated with having ADHD: an umbrella review. Frontiers in Psychiatry, 15, Article 1343314. https://doi.org/10.3389/fpsyt.2024.1343314

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention. These symptoms are significantly impairing and carry additional risks for... Read More about The impacts associated with having ADHD: an umbrella review.

Transgender and gender diverse older people: health, aging and dementia (2024)
Journal Article
Asti, E., Beale, N., Thorne, N., & Dening, T. (2024). Transgender and gender diverse older people: health, aging and dementia. International Journal of Transgender Health, https://doi.org/10.1080/26895269.2024.2355232

Background and Objectives
262,000 people in the UK identify as transgender and gender diverse (TGD), and this population is believed to be growing. As the population is aging, an increase in older TGD people accessing health and social care can be a... Read More about Transgender and gender diverse older people: health, aging and dementia.

Systematic review and meta-analysis:relative age in attention-deficit/ hyperactivity disorder and autism spectrum disorder (2024)
Journal Article
Frisira, E., Holland, J., & Sayal, K. (2024). Systematic review and meta-analysis:relative age in attention-deficit/ hyperactivity disorder and autism spectrum disorder. European Child and Adolescent Psychiatry, https://doi.org/10.1007/s00787-024-02459-x

Youngest students in their class, with birthdates just before the school entry cut-off date, are overrepresented among children receiving an Attention-Deficit/Hyperactivity Disorder (ADHD) diagnosis or medication for this. This is known as the relati... Read More about Systematic review and meta-analysis:relative age in attention-deficit/ hyperactivity disorder and autism spectrum disorder.

Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol (2024)
Journal Article
Chouliara, N., Cameron, T., Ballard-Ridley, S., Fisher, R. J., Kettlewell, J., Kidd, L., …Gordon, A. L. (2024). Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol. Healthcare, 12(10), Article 1027. https://doi.org/10.3390/healthcare12101027

Telerehabilitation (TR) shows promise as a method of remote service delivery, yet there is little guidance to inform implementation in the context of the National Health Service (NHS) in England. This paper presents the protocol for a realist synthes... Read More about Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol.

A Nonrandomized Pilot Implementation Trial of the CLASS PAL (Physically Active Learning) Project (2024)
Journal Article
Routen, A. C., Cale, L., Chalkley, A. E., Clemes, S., Edwardson, C. L., Glazebrook, C., Harrington, D. M., Khunti, K., Pearson, N., Salmon, J., & Sherar, L. B. (2024). A Nonrandomized Pilot Implementation Trial of the CLASS PAL (Physically Active Learning) Project. Translational Journal of the American College of Sports Medicine, 9(2), Article e000261. https://doi.org/10.1249/tjx.0000000000000261

Purpose To determine the a) implementation of CLASS PAL (Physically Active Learning), b) implementation process of CLASS PAL, and c) influence of the inner setting (i.e., school) and individuals (teachers and pupils) on the implementation of CLASS PA... Read More about A Nonrandomized Pilot Implementation Trial of the CLASS PAL (Physically Active Learning) Project.

Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function (2024)
Journal Article
Hashmat, A., Ya, J., Kadir, R., Alwjwaj, M., & Bayraktutan, U. (2024). Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function. Tissue Barriers, Article 2350821. https://doi.org/10.1080/21688370.2024.2350821

Breakdown of blood-brain barrier (BBB) represents a key pathology in hyperglycemia-mediated cerebrovascular damage after an ischemic stroke. As changes in the level and nature of vasoactive agents released by endothelial cells (ECs) may contribute to... Read More about Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function.

The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact (2024)
Journal Article
Kalaria, R., Maestre, G., Mahinrad, S., Acosta, D. M., Akinyemi, R. O., Alladi, S., Allegri, R. F., Arshad, F., Babalola, D. O., Baiyewu, O., Bak, T. H., Bellaj, T., Brodie‐Mends, D. K., Carrillo, M. C., Celestin, K., Damasceno, A., de Silva, R. K., de Silva, R., Djibuti, M., Dreyer, A. J., …Ismail, O. (2024). The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(6), 4290-4314. https://doi.org/10.1002/alz.13836

Two of every three persons living with dementia reside in low‐ and middle‐income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs oc... Read More about The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact.

Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial (2024)
Journal Article
Andrén, P., Sampaio, F., Ringberg, H., Wachtmeister, V., Warnström, M., Isomura, K., Aspvall, K., Lenhard, F., Hall, C. L., Davies, E. B., Murphy, T., Hollis, C., Feldman, I., Bottai, M., Serlachius, E., Andersson, E., Fernández de la Cruz, L., & Mataix-Cols, D. (2024). Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial. JAMA Network Open, 7(5), Article e248468. https://doi.org/10.1001/jamanetworkopen.2024.8468

Importance: Behavior therapy is a recommended intervention for Tourette syndrome (TS) and chronic tic disorder (CTD), but availability is limited and long-term effects are uncertain.

Objective: To investigate the long-term efficacy and cost-effec... Read More about Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial.

Dysphagia after stroke: research advances in treatment interventions (2024)
Journal Article
Labeit, B., Michou, E., Trapl-Grundschober, M., Suntrup-Krueger, S., Muhle, P., Bath, P. M., & Dziewas, R. (2024). Dysphagia after stroke: research advances in treatment interventions. Lancet Neurology, 23(4), 418-428. https://doi.org/10.1016/s1474-4422%2824%2900053-x

After a stroke, most patients have dysphagia, which can lead to aspiration pneumonia, malnutrition, and adverse functional outcomes. Protective interventions aimed at reducing these complications remain the cornerstone of treatment. Dietary adjustmen... Read More about Dysphagia after stroke: research advances in treatment interventions.

More absence, but less impact on business performance. What can we learn from Swedish approaches to managing workplace mental health? (2024)
Report
Wishart, M., Roper, S., Belt, V., Bourke, J., Hassard, J., Blake, H., …Leka, S. (2024). More absence, but less impact on business performance. What can we learn from Swedish approaches to managing workplace mental health?. Enterprise Research Centre

Using employer-level survey data, this report compares how firms in England, Ireland and Sweden are responding to the challenges of workplace mental health. The three countries adopt very different approaches to the funding and provision of healthcar... Read More about More absence, but less impact on business performance. What can we learn from Swedish approaches to managing workplace mental health?.

Age Deficits in Associative Memory Are Not Alleviated by Multisensory Paradigms (2024)
Journal Article
Badham, S. P., Atkin, C., Stacey, J. E., Henshaw, H., Allen, H. A., & Roberts, K. L. (2024). Age Deficits in Associative Memory Are Not Alleviated by Multisensory Paradigms. Journals of Gerontology, Series B, 79(7), Article gbae063. https://doi.org/10.1093/geronb/gbae063

OBJECTIVES: Age deficits in memory are widespread, this affects individuals at a personal level, and investigating memory has been a key focus in cognitive aging research. Age deficits occur in memory for an episode, where information from the enviro... Read More about Age Deficits in Associative Memory Are Not Alleviated by Multisensory Paradigms.

Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives (2024)
Journal Article
Tucker, R., Vickers, R., Adams, E. J., Burgon, C., Lock, J., Goldberg, S. E., …Harwood, R. H. (2024). Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives. Archives of Public Health, 82(1), Article 54. https://doi.org/10.1186/s13690-024-01283-8

Background
Despite several interventions demonstrating benefit to people living with dementia and their caregivers, few have been translated and implemented in routine clinical practice. There is limited evidence of the barriers and facilitators for... Read More about Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives.

Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies (2024)
Journal Article
Lim, A., Ma, H., Johnston, S. C., Singhal, S., Muthusamy, S., Wang, Y., …Phan, T. G. (2024). Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies. Journal of the American Heart Association, 13(9), Article e032471. https://doi.org/10.1161/jaha.123.032471

Background Risk of recurrence after minor ischemic stroke is usually reported with transient ischemic attack. No previous meta‐analysis has focused on minor ischemic stroke alone. The objective was to evaluate the pooled proportion of 90‐day stroke r... Read More about Ninety‐Day Stroke Recurrence in Minor Stroke: Systematic Review and Meta‐Analysis of Trials and Observational Studies.