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All Outputs (355)

Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach (2024)
Journal Article
Radford, K., Kettlewell, J., das Nair, R., Morriss, R., Holmes, J., Kellezi, B., Timmons, S., Jones, T., Tressider, H., Andrews, I., Bridger, K., Patel, P., Lindley, R., De Dios Perez, B., Statham, A., Jones, T., Hoffman, K., James, M., Kendrick, D., & ROWTATE study team. (in press). Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach. BMJ Open,

Objectives: Major trauma centres save lives but rehabilitation to support return-to-work (RTW) is lacking. This paper describes development of a vocational rehabilitation intervention (the ROWTATE intervention) to support RTW following traumatic inju... Read More about Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach.

Categorising interventions to enhance vaccine uptake or reduce vaccine hesitancy in the United Kingdom: A systematic review and meta-analysis (2024)
Journal Article
Kafadar, A. H., Sabatini, S., Jones, K. A., & Dening, T. (2024). Categorising interventions to enhance vaccine uptake or reduce vaccine hesitancy in the United Kingdom: A systematic review and meta-analysis. Vaccine, https://doi.org/10.1016/j.vaccine.2024.06.059

Background: Vaccination is one of the most important public health interventions to combat infectious disease. However, vaccine hesitancy prevents us reaching the global target of vaccine uptake (e.g., 75 % of influenza vaccination in at-risk groups)... Read More about Categorising interventions to enhance vaccine uptake or reduce vaccine hesitancy in the United Kingdom: A systematic review and meta-analysis.

Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences (2024)
Preprint / Working Paper
Deakin, B., Liddle, E., Rathnaiah, M., Gregory, C., Katshu, M., Wiliams, G., Conen, S., Smallman, R., Koelewijn, L. C., Anton, A., Kumar, J., Gasgoyne, L. E., Chen, C., Nikkheslat, N., Evans, J., Lanz, B., Walters, J., Talbot, P., Palaniyappan, L., Singh, K. D., …Liddle, P. F. Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences

It is widely thought that the onset of psychotic symptoms in schizophrenia may arise from an early neurotoxic phase, possibly related to oxidative stress or inflammation, and a late residual damage phase associated with persistent negative symptoms.... Read More about Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences.

Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire (2024)
Journal Article
McWilliams, D., Georgopoulos, V., Patel, J., Millar, B., Smith, S., & Walsh, D. (2024). Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire. Rheumatology, https://doi.org/10.1093/rheumatology/keae342

Background Neuropathic-like pain, fatigue, cognitive difficulty, catastrophizing, anxiety, sleep disturbance, depression and widespread pain associate with a single factor in people with knee pain. We report the Central Aspects of Pain questionnai... Read More about Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire.

Uses of Linguistic Context in Speech Listening: Does Acquired Hearing Loss Lead to Reduced Engagement of Prediction? (2024)
Journal Article
Fernandez, L. B., Pickering, M. J., Naylor, G., & Hadley, L. V. (2024). Uses of Linguistic Context in Speech Listening: Does Acquired Hearing Loss Lead to Reduced Engagement of Prediction?. Ear and Hearing, https://doi.org/10.1097/AUD.0000000000001515

Research investigating the complex interplay of cognitive mechanisms involved in speech listening for people with hearing loss has been gaining prominence. In particular, linguistic context allows the use of several cognitive mechanisms that are not... Read More about Uses of Linguistic Context in Speech Listening: Does Acquired Hearing Loss Lead to Reduced Engagement of Prediction?.

Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome (2024)
Report
French, B., & Groom, M. (2024). Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome. University of Nottingham

Around 15-20% of the population is neurodivergent. Despite this, access to diagnoses and care for neurodivergent people is problematic and there is inconsistent support across the UK. Research at the University of Nottingham focuses on the impor... Read More about Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome.

Evaluation of factors predicting tinnitus outcomes following cochlear implantation: Protocol for a prospective quasi-experimental study (2024)
Journal Article
Labree, B., Sereda, M., Cullington, H., Johnson, S., Church, P., Dunster, J., & Hoare, D. J. (2024). Evaluation of factors predicting tinnitus outcomes following cochlear implantation: Protocol for a prospective quasi-experimental study. PLoS ONE, 19(6), Article e0302790. https://doi.org/10.1371/journal.pone.0302790

Cochlear implantation is an effective intervention to restore useful aspects of hearing function in adults with severe-to-profound hearing loss. Tinnitus, the perception of sound in the absence of an external source, is common in people with severe-t... Read More about Evaluation of factors predicting tinnitus outcomes following cochlear implantation: Protocol for a prospective quasi-experimental study.

Exploring access to support services for medical students: recommendations for enhancing wellbeing support (2024)
Journal Article
Hawsawi, A. A., Nixon, N., Stewart, E., & Nixon, E. (2024). Exploring access to support services for medical students: recommendations for enhancing wellbeing support. BMC Medical Education, 24, Article 671. https://doi.org/10.1186/s12909-024-05492-1

Background Medical students have reported facing unique challenges in their academic journey that can have a significant impact on their mental health and wellbeing; therefore, their access to support services and wellbeing resources has been deemed... Read More about Exploring access to support services for medical students: recommendations for enhancing wellbeing support.

Sex differences in attention‐deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales (2024)
Journal Article
Martin, J., Langley, K., Cooper, M., Rouquette, O. Y., John, A., Sayal, K., Ford, T., & Thapar, A. (2024). Sex differences in attention‐deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.13987

Background Population-based studies have observed sex biases in the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD). Females are less likely to be diagnosed or prescribed ADHD medication. This study uses national healthcar... Read More about Sex differences in attention‐deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales.

Primary central nervous system lymphomas: EHA-ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up (2024)
Journal Article
Ferreri, A., Illerhaus, G., Doorduijn, J., Auer, D., Bromberg, J., Calimeri, T., Cwynarski, K., Fox, C., Hoang-Xuan, K., Malaise, D., Ponzoni, M., Schorb, E., Soussain, C., Specht, L., Zucca, E., Buske, C., Jerkeman, M., & Dreyling, M. (2024). Primary central nervous system lymphomas: EHA-ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology, 35(6), 491-507. https://doi.org/10.1016/j.annonc.2023.11.010

Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context (2024)
Journal Article
Taher, R., Bhanushali, P., Allan, S., Alvarez-Jimenez, M., Bolton, H., Dennison, L., …Yiend, J. (2024). Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context. BJPsych Open, 10(4), Article e126. https://doi.org/10.1192/bjo.2024.713

Background Digital Mental Health Interventions (DMHIs) that meet the definition of a medical device are regulated by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK. The MHRA uses procedures that were originally developed fo... Read More about Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context.

A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of Well Parent Japan in routine care in Japan: The training and nurturing support for mothers (TRANSFORM) study (2024)
Journal Article
Shimabukuro, S., Oshio, T., Endo, T., Harada, S., Yamashita, Y., Tomoda, A., …Tripp, G. (2024). A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of Well Parent Japan in routine care in Japan: The training and nurturing support for mothers (TRANSFORM) study. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.14007

Background Well Parent Japan (WPJ) is a new hybrid group parent training programme combining sessions to improve mothers' psychological well-being with a culturally adapted version of the New Forest Parenting Programme (NFPP). This study investigate... Read More about A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of Well Parent Japan in routine care in Japan: The training and nurturing support for mothers (TRANSFORM) study.

Pathways between digital activity and depressed mood in adolescence: outlining a developmental model integrating risk, reactivity, resilience and reciprocity (2024)
Journal Article
Sonuga-Barke, E. J., Stoilova, M., Kostyrka-Allchorne, K., Bourgaize, J., Murray, A., Tan, M. P., Hollis, C., Townsend, E., & Livingstone, S. (2024). Pathways between digital activity and depressed mood in adolescence: outlining a developmental model integrating risk, reactivity, resilience and reciprocity. Current Opinion in Behavioral Sciences, 58, Article 101411. https://doi.org/10.1016/j.cobeha.2024.101411

Digital technology use (i.e. digital activity) has been proposed to contribute to a decline in adolescents’ mental health. We present a new model of how risky digital activity may increase depressed mood via reciprocal pathways, cre... Read More about Pathways between digital activity and depressed mood in adolescence: outlining a developmental model integrating risk, reactivity, resilience and reciprocity.

Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review (2024)
Journal Article
Kontou, E., Shokraneh, F., das Nair, R., Quinn, T., Leonardi-Bee, J., Thorpe, N., …Drummond, A. (2024). Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review. F1000Research, 13, 1-15. https://doi.org/10.12688/f1000research.146343.2

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, pu... Read More about Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review.

An alternative theoretical approach to develop a new conception about pain in people with dementia (2024)
Journal Article
Morgner, C., Dening, K. H., Dening, T., & Gibson, B. (2024). An alternative theoretical approach to develop a new conception about pain in people with dementia. Medical Humanities, https://doi.org/10.1136/medhum-2023-012718

The theoretical approach presented in this paper describes a novel experimental-theoretical methodology to conceptualise pain in people with dementia. Existing procedures for assessment of pain rely on subjective self-report using pain questionnaires... Read More about An alternative theoretical approach to develop a new conception about pain in people with dementia.

Dynamical and individualised approach of transcranial ultrasound neuromodulation effects in non-human primates (2024)
Journal Article
Atkinson-Clement, C., Alkhawashki, M., Ross, J., Gatica, M., Zhang, C., Sallet, J., & Kaiser, M. (2024). Dynamical and individualised approach of transcranial ultrasound neuromodulation effects in non-human primates. Scientific Reports, 14, Article 11916. https://doi.org/10.1038/s41598-024-62562-6

Low-frequency transcranial ultrasound stimulation (TUS) allows to alter brain functioning with a high spatial resolution and to reach deep targets. However, the time-course of TUS effects remains largely unknown. We applied TUS on three brain targets... Read More about Dynamical and individualised approach of transcranial ultrasound neuromodulation effects in non-human primates.

The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial (2024)
Journal Article
Hollingworth, M., Woodhouse, L. J., Law, Z. K., Ali, A., Krishnan, K., Dineen, R. A., Christensen, H., England, T. J., Roffe, C., Werring, D., Peters, N., Ciccone, A., Robinson, T., Członkowska, A., Bereczki, D., Egea-Guerrero, J. J., Ozturk, S., Bath, P. M., & Sprigg, N. (2024). The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial. Neurosurgery, https://doi.org/10.1227/neu.0000000000002961

BACKGROUND AND OBJECTIVES: An important proportion of patients with spontaneous intracerebral hemorrhage (ICH) undergo neurosurgical intervention to reduce mass effect from large hematomas and control the complications of bleeding, including hemato... Read More about The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial.

Impact of NICE technology appraisal guidance TA566 on access to cochlear implantation for children using hearing aids in the United Kingdom: a multisite observational study (2024)
Journal Article
Killan, C. F., Hoare, D. J., Hartley, D. E., Church, P., Isherwood, F., Nasim, S., …Kitterick, P. T. (2024). Impact of NICE technology appraisal guidance TA566 on access to cochlear implantation for children using hearing aids in the United Kingdom: a multisite observational study. Archives of Disease in Childhood, 109(8), 690-691. https://doi.org/10.1136/archdischild-2023-326055

The impacts associated with having ADHD: an umbrella review (2024)
Journal Article
French, B., Nalbant, G., Wright, H., Sayal, K., Daley, D., Groom, M. J., …Hall, C. L. (2024). The impacts associated with having ADHD: an umbrella review. Frontiers in Psychiatry, 15, Article 1343314. https://doi.org/10.3389/fpsyt.2024.1343314

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention. These symptoms are significantly impairing and carry additional risks for... Read More about The impacts associated with having ADHD: an umbrella review.