All Outputs (395)

Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial (2023)
Preprint / Working Paper
Khan, K., Hall, C. L., Babbage, C., Dodzo, S., Greenhalgh, C., Lucassen, M., Merry, S., Sayal, K., Sprange, K., Stasiak, K., Tench, C. R., Townsend, E., Stallard, P., & Hollis, C. Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial

Background:

A serious game (SPARX), developed in New Zealand and incorporating cognitive behavioural therapy (CBT) principles, has been shown to help reduce symptoms of depression and anxiety in adolescents with mild to moderate depression. Howev... Read More about Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial.

The effect of unisensory and multisensory information on lexical decision and free recall in young and older adults (2023)
Journal Article
Atkin, C., Stacey, J. E., Roberts, K. L., Allen, H. A., Henshaw, H., & Badham, S. P. (2023). The effect of unisensory and multisensory information on lexical decision and free recall in young and older adults. Scientific Reports, 13, Article 16575. https://doi.org/10.1038/s41598-023-41791-1

Studies using simple low-level stimuli show that multisensory stimuli lead to greater improvements in processing speed for older adults than young adults. However, there is insufficient evidence to explain how these benefits influence performance for... Read More about The effect of unisensory and multisensory information on lexical decision and free recall in young and older adults.

Unified Surface and Volumetric Inference on Functional Imaging Data (2023)
Presentation / Conference Contribution
Kirk, T. F., Craig, M. S., & Chappell, M. A. (2023). Unified Surface and Volumetric Inference on Functional Imaging Data. In J. Duncan, H. Greenspan, A. Madabhushi, P. Mousavi, S. Salcudean, T. Syeda-Mahmood, & R. Taylor (Eds.), Medical Image Computing and Computer Assisted Intervention – MICCAI 2023: 26th International Conference, Vancouver, BC, Canada, October 8–12, 2023, Proceedings, Part VIII (399-408). https://doi.org/10.1007/978-3-031-43993-3_39

Surface-based analysis methods for functional imaging data have been shown to offer substantial benefits for the study of the human cortex, namely in the localisation of functional areas and the establishment of inter-subject correspondence. A new ap... Read More about Unified Surface and Volumetric Inference on Functional Imaging Data.

Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study (2023)
Journal Article
Kai, J., Dutton, B., Vinogradova, Y., Hilken, N., Gupta, J., & Daniels, J. (2023). Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study. Health Technology Assessment, 27(17), https://doi.org/10.3310/jhsw0174

Background: Heavy menstrual bleeding is a common problem that can significantly affect women’s lives until menopause. There is a lack of evidence on longer-term outcomes after seeking health care and treatment for heavy menstrual bleeding. Objectives... Read More about Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study.

The assessment of dysphagia after stroke: state of the art and future directions (2023)
Journal Article
Labeit, B., Michou, E., Hamdy, S., Trapl-Grundschober, M., Suntrup-Krueger, S., Muhle, P., …Dziewas, R. (2023). The assessment of dysphagia after stroke: state of the art and future directions. Lancet Neurology, 22(9), 858-870. https://doi.org/10.1016/S1474-4422%2823%2900153-9

Dysphagia is a major complication following an acute stroke that affects the majority of patients. Clinically, dysphagia after stroke is associated with increased risk of aspiration pneumonia, malnutrition, mortality, and other adverse functional out... Read More about The assessment of dysphagia after stroke: state of the art and future directions.

Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials (2023)
Journal Article
Krishnan, K., Campos, P. B., Nguyen, T. N., Tan, C. W., Chan, S. L., Appleton, J. P., …Bath, P. M. (2023). Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials. Frontiers in Stroke, 2, Article 1256664. https://doi.org/10.3389/fstro.2023.1256664

Acute intracerebral hemorrhage is the most devastating stroke subtype and is associated with significant morbidity and mortality. Poor prognosis is associated with primary brain injury from the presenting hematoma, and despite advances in clinical tr... Read More about Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials.

Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. (2023)
Journal Article
Murray, A. J., Humpston, C. S., Wilson, M., Rogers, J. C., Zia Ul Haq Katshu, M., Liddle, P. F., & Upthegrove, R. (2024). Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. Brain, Behavior, and Immunity, 115, 3-12. https://doi.org/10.1016/j.bbi.2023.09.017

Oxidative stress may contribute to declining course and poor outcomes in psychosis. However, in vivo Magnetic Resonance Spectroscopy studies yield disparate results due to clinical stage, sample demographics, neuroanatomical focus, sample size, and a... Read More about Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis..

Examining the Use of Autonomous Systems for Home Health Support Using a Smart Mirror (2023)
Journal Article
Dowthwaite, L., Reyes Cruz, G., Pena, A. R., Pepper, C., Jäger, N., Barnard, P., …Benford, S. (2023). Examining the Use of Autonomous Systems for Home Health Support Using a Smart Mirror. Healthcare, 11(19), Article 2608. https://doi.org/10.3390/healthcare11192608

The home is becoming a key location for healthcare delivery, including the use of technology driven by autonomous systems (AS) to monitor and support healthcare plans. Using the example of a smart mirror, this paper describes the outcomes of focus gr... Read More about Examining the Use of Autonomous Systems for Home Health Support Using a Smart Mirror.

Tools and methods for evaluating the change to health service delivery due to pandemics or other similar emergencies: A rapid evidence review. (2023)
Journal Article
Keegan, D., Heffernan, E., Clarke, B., Deasy, C., O'Donnell, C., Crowley, P., …Masterson, S. (2024). Tools and methods for evaluating the change to health service delivery due to pandemics or other similar emergencies: A rapid evidence review. Evaluation and Program Planning, 102, Article 102378. https://doi.org/10.1016/j.evalprogplan.2023.102378

The novel coronavirus, SARS-CoV-2 and its associated disease COVID-19, were declared a pandemic in March 2020. Countries developed rapid response activities within their health services to prevent spread of the virus and protect their populations. Ev... Read More about Tools and methods for evaluating the change to health service delivery due to pandemics or other similar emergencies: A rapid evidence review..

Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study (2023)
Journal Article
Iflaifel, M., Hall, C. L., Green, H. R., Willis, A., Rennick-Egglestone, S., Juszczak, E., …Sprange, K. (2023). Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study. BMC Medical Research Methodology, 23(1), Article 211. https://doi.org/10.1186/s12874-023-02032-1

Background: Barriers to mental health research participation are well documented including distrust of services and research; and stigma surrounding mental health. They can contribute to a lack of diversity amongst participants in mental health resea... Read More about Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study.

Police officers' perception of community support for policing: implications for well-being (2023)
Journal Article
Keaton, J., Jennings Black, K., Houdmont, J., Beck, E., Roddy, D., Chambers, J., & Moon, S. (2023). Police officers' perception of community support for policing: implications for well-being. Policing: An International Journal of Police Strategies and Management, 46(5/6), 811-830. https://doi.org/10.1108/PIJPSM-05-2023-0056

Purpose: Community-police relations have gained increasing public attention during the past decade. The purpose of the present study was to better understand the relationship between perceived community support and police officer burnout and engageme... Read More about Police officers' perception of community support for policing: implications for well-being.

Violence risk assessment instruments in forensic psychiatric populations: a systematic review and meta-analysis (2023)
Journal Article
Ogonah, M. G. T., Seyedsalehi, A., Whiting, D., & Fazel, S. (2023). Violence risk assessment instruments in forensic psychiatric populations: a systematic review and meta-analysis. Lancet Psychiatry, 10(10), 780-789. https://doi.org/10.1016/S2215-0366%2823%2900256-0

Although structured tools have been widely used to predict violence risk in specialist mental health settings, there is uncertainty about the extent and quality of evidence of their predictive performance. We aimed to systematically review the predic... Read More about Violence risk assessment instruments in forensic psychiatric populations: a systematic review and meta-analysis.

Remote Recruitment Strategy and Structured E-Parenting Support (STEPS) App: Feasibility and Usability Study (2023)
Journal Article
Kostyrka-Allchorne, K., Chu, P., Ballard, C., Lean, N., French, B., Hedstrom, E., …Sonuga-Barke, E. J. (2023). Remote Recruitment Strategy and Structured E-Parenting Support (STEPS) App: Feasibility and Usability Study. JMIR Pediatrics and Parenting, 6(1), Article e47035. https://doi.org/10.2196/47035

Background: The Structured E-Parenting Support (STEPS) app [1] provides support for parents of children with elevated levels of hyperactivity/impulsivity, inattention, and conduct problems, awaiting clinical assessment by child health services. STEPS... Read More about Remote Recruitment Strategy and Structured E-Parenting Support (STEPS) App: Feasibility and Usability Study.

Application and Extension of the Alcohol Recovery Narratives Conceptual Framework (2023)
Journal Article
Subhani, M., Talat, U., Knight, H., Morling, J. R., Jones, K. A., Aithal, G. P., …Rennick-Egglestone, S. (2023). Application and Extension of the Alcohol Recovery Narratives Conceptual Framework. Qualitative Health Research, 33(13), 1203-1217. https://doi.org/10.1177/10497323231197384

Recovery narratives are personal stories of health problems and recovery. A systematic review proposed a conceptual framework characterising alcohol misuse recovery narratives, consisting of eight principal dimensions, each with types and subtypes. T... Read More about Application and Extension of the Alcohol Recovery Narratives Conceptual Framework.

A systematic review of dentists' psychological wellbeing during the COVID-19 pandemic (2023)
Journal Article
Lefkowitz, B., Houdmont, J., & Knight, A. (2023). A systematic review of dentists' psychological wellbeing during the COVID-19 pandemic. British Dental Journal, https://doi.org/10.1038/s41415-023-6232-8

Background: The COVID-19 pandemic presented significant challenges to healthcare workers worldwide, including the effect on the psychological wellbeing of dentists.

Aims: To evaluate the impact of the early phases of the pandemic on the psychologi... Read More about A systematic review of dentists' psychological wellbeing during the COVID-19 pandemic.

Using intervention mapping to develop evidence-based toolkits that support workers on long-term sick leave and their managers (2023)
Journal Article
Varela-Mato, V., Blake, H., Yarker, J., Godfree, K., Daly, G., Hassard, J., …Munir, F. (2023). Using intervention mapping to develop evidence-based toolkits that support workers on long-term sick leave and their managers. BMC Health Services Research, 23, Article 942. https://doi.org/10.1186/s12913-023-09952-0

Background: Managing long-term sickness absence is challenging in countries where employers and managers have the main responsibility to provide return to work support, particularly for workers with poor mental health. Whilst long-term sick leave and... Read More about Using intervention mapping to develop evidence-based toolkits that support workers on long-term sick leave and their managers.

Effectiveness of Violence Prevention Interventions: Umbrella Review of Research in the General Population (2023)
Journal Article
Fazel, S., Burghart, M., Wolf, A., Whiting, D., & Yu, R. (2024). Effectiveness of Violence Prevention Interventions: Umbrella Review of Research in the General Population. Trauma, Violence, and Abuse, 25(2), 1709-1718. https://doi.org/10.1177/15248380231195880

To address the societal harms of violence, many violence prevention interventions have been developed, tested, and implemented in the general population. These have been reported in systematic reviews and meta-analyses, which have typically focused o... Read More about Effectiveness of Violence Prevention Interventions: Umbrella Review of Research in the General Population.

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., …Adams, E. (2023). Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial. BMJ, 382, Article e074787. https://doi.org/10.1136/bmj-2023-074787

Objective: To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care.

Design: Randomised controlled trial.

Setting: Participant... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): randomised controlled trial.

Device-based interventions that seek to restore bilateral and binaural hearing in adults with single-sided deafness: a conceptual analysis (2023)
Journal Article
Katiri, R., Peters, J. P. M., Fackrell, K., & Hoare, D. J. (2023). Device-based interventions that seek to restore bilateral and binaural hearing in adults with single-sided deafness: a conceptual analysis. Frontiers in Audiology and Otology, 1, Article 1242196. https://doi.org/10.3389/fauot.2023.1242196

Single-sided deafness (SSD) is defined by severe-to-profound sensorineural hearing loss in one ear only. This article outlines the etiologies and associated functional, psychological, social, and other consequences of SSD in adulthood. The available... Read More about Device-based interventions that seek to restore bilateral and binaural hearing in adults with single-sided deafness: a conceptual analysis.

Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., Hoare, Z., Hancox, J., Bajwa, R., Burgon, C., Howe, L., Cowley, A., Bramley, T., Long, A., Lock, J., Tucker, R., Adams, E. J., O’Brien, R., Kearney, F., Kowalewska, K., …Masud, T. (2023). Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial. BMJ, 382, Article e074787. https://doi.org/10.1136/bmj-2023-074787

Objective To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care.

Design Randomised controlled trial.

Setting Participants’... Read More about Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial.