All Outputs (387)

Differences between online trial participants who have used statutory mental health services and who have not: analysis of baseline data from two pragmatic trials of a digital health intervention (2023)
Preprint / Working Paper
Rennick-Egglestone, S., Newby, C., Robinson, C., Yeo, C., Ng, F., Elliott, R. A., Ali, Y., Llewellyn-Beardsley, J., Pomberth, S., Harrison, J., Gavan, S. P., Cuijpers, P., Priebe, S., Hall, C. L., & Slade, M. Differences between online trial participants who have used statutory mental health services and who have not: analysis of baseline data from two pragmatic trials of a digital health intervention

Background:
Digital health interventions have become an established part of mental health service provision internationally. Regulators have positioned the best-practice standard of evidence as an interventional study with a comparator reflective of... Read More about Differences between online trial participants who have used statutory mental health services and who have not: analysis of baseline data from two pragmatic trials of a digital health intervention.

A mixed-methods feasibility case series of a job retention vocational rehabilitation intervention for people with multiple sclerosis (2023)
Journal Article
De Dios Pérez, B., das Nair, R., & Radford, K. (2024). A mixed-methods feasibility case series of a job retention vocational rehabilitation intervention for people with multiple sclerosis. Disability and Rehabilitation, 46(5), 875-886. https://doi.org/10.1080/09638288.2023.2181411

Purpose: To ascertain the feasibility and acceptability of delivering a job retention vocational rehabilitation intervention [MSVR] for people with multiple sclerosis (pwMS) in a community setting. Secondary objectives included determining whether MS... Read More about A mixed-methods feasibility case series of a job retention vocational rehabilitation intervention for people with multiple sclerosis.

Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol (2023)
Presentation / Conference Contribution
Stein, A., Iyer, K., Dux, P., Friehs, M., Riddle, J., Craven, M., …Barlow, K. (2023, February). Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol. Poster presented at 5th International Brain Stimulation Conference, Lisbon, Portugal

Introduction: Traumatic brain injury (TBI) is the most common acquired brain injury (ABI), where 16% of children sustain at least one TBI requiring medical attention, and 25-30% experience chronic problems. Attention and concentration problems are am... Read More about Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol.

Impact of the COVID-19 pandemic on incidence of tics in children and young people: a population-based cohort study (2023)
Journal Article
Jack, R. H., Joseph, R. M., Coupland, C. A., Hall, C. L., & Hollis, C. (2023). Impact of the COVID-19 pandemic on incidence of tics in children and young people: a population-based cohort study. eClinicalMedicine, 57, Article 101857. https://doi.org/10.1016/j.eclinm.2023.101857

Background: Since the onset of the coronavirus (COVID-19) pandemic, clinicians have reported an increase in presentations of sudden and new onset tics particularly affecting teenage girls. This population-based study aimed to describe and compare the... Read More about Impact of the COVID-19 pandemic on incidence of tics in children and young people: a population-based cohort study.

Factors influencing COVID-19 health protective behaviours in Zambian university students with symptoms of low mood (2023)
Journal Article
Ncheka, J. M., Menon, J. A., Davies, E. B., Paul, R., Mwaba, S. O. C., Mudenda, J., …Glazebrook, C. (2023). Factors influencing COVID-19 health protective behaviours in Zambian university students with symptoms of low mood. BMC Public Health, 23(1), Article 336. https://doi.org/10.1186/s12889-023-15073-4

Background
Health protective behaviours are crucial in the prevention of the spread of COVID-19, particularly in university students who typically live and study in large groups. Depression and anxiety are common in students and can impact young peo... Read More about Factors influencing COVID-19 health protective behaviours in Zambian university students with symptoms of low mood.

How people with knee pain understand why their pain changes or remains the same over time: A qualitative study (2023)
Journal Article
Walsh, D. A., Rathbone, J., Akin-Akinyosoye, K., Fernandes, G. S., Valdes, A. M., McWilliams, D. F., …Ferguson, E. (2023). How people with knee pain understand why their pain changes or remains the same over time: A qualitative study. Osteoarthritis and Cartilage Open, 5(2), Article 100345. https://doi.org/10.1016/j.ocarto.2023.100345

Objectives
Guidelines recommend knee osteoarthritis pain management based on biopsychosocial mechanisms. Treatment adherence and effectiveness may be affected if there is a mismatch between patient perspectives and treatment focus. We therefore exam... Read More about How people with knee pain understand why their pain changes or remains the same over time: A qualitative study.

The executive disruption model of tinnitus distress: Model validation in two independent datasets using factor score regression (2023)
Journal Article
Clarke, N. A., Akeroyd, M. A., Henshaw, H., Hall, D. A., Mohamad, W. N. W., & Hoare, D. J. (2023). The executive disruption model of tinnitus distress: Model validation in two independent datasets using factor score regression. Frontiers in Psychology, 14, Article 1006349. https://doi.org/10.3389/fpsyg.2023.1006349

This study presents the executive disruption model (EDM) of tinnitus distress and subsequently validates it statistically using two independent datasets (the Construction Dataset: n = 96 and the Validation Dataset: n = 200). The conceptual EDM was fi... Read More about The executive disruption model of tinnitus distress: Model validation in two independent datasets using factor score regression.

The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline (2023)
Journal Article
Thomas, E. O., Manara, A., Dineen, R. A., Mortimer, A., Aziz, O., Dean, P., …Gardiner, D. (2023). The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline. Anaesthesia, 78(3), 330-336. https://doi.org/10.1111/anae.15950

This multidisciplinary consensus statement was produced following a recommendation by the Faculty of Intensive Care Medicine to develop a UK guideline for ancillary investigation, when one is required, to support the diagnosis of death using neurolog... Read More about The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline.

Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack (2023)
Journal Article
Krishnan, K., Nguyen, T. N., Appleton, J. P., Law, Z. K., Caulfied, M., Cabrera, C. P., …Bath, P. M. (2023). Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack. Stroke: Vascular and Interventional Neurology, 3(3), Article e000576. https://doi.org/10.1161/svin.122.000576

Acute ischemic stroke is a leading cause of death and major disability worldwide. Approximately 50% of ischemic strokes are caused by atherothrombotic occlusion of the cerebral arteries, and antiplatelets are the mainstay of secondary stroke preventa... Read More about Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack.

Inferring the basis of binaural detection with a modified autoencoder (2023)
Journal Article
Smith, S., Sollini, J., & Akeroyd, M. A. (2023). Inferring the basis of binaural detection with a modified autoencoder. Frontiers in Neuroscience, 17, Article 1000079. https://doi.org/10.3389/fnins.2023.1000079

The binaural system utilizes interaural timing cues to improve the detection of auditory signals presented in noise. In humans, the binaural mechanisms underlying this phenomenon cannot be directly measured and hence remain contentious. As an alterna... Read More about Inferring the basis of binaural detection with a modified autoencoder.

Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study (2023)
Journal Article
Tindall, T., Topcu, G., Thomas, S., Bale, C., Evangelou, N., Drummond, A., & das Nair, R. (2023). Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study. Health Expectations, 26(2), 858-868. https://doi.org/10.1111/hex.13711

Background: Diagnosing multiple sclerosis (MS) can be a lengthy process, which can impact psychological wellbeing, condition management, and future engagement with health services. Therefore, providing timely and appropriate emotional support may imp... Read More about Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study.

Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial (2023)
Journal Article
Hollis, C., Hall, C. L., Khan, K., Jones, R., Marston, L., Le Novere, M., …Murphy, T. (2023). Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial. Journal of Child Psychology and Psychiatry, 64(6), 941-951. https://doi.org/10.1111/jcpp.13756

Background: Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 a... Read More about Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial.

Patient and Public Involvement and Engagement for PhD Students (2023)
Preprint / Working Paper
Gladman, J. R. F., Stocks, J., Phillips, B., Horobin, A., Wragg, A., Mundey, M., …Humes, D. (2022). Patient and Public Involvement and Engagement for PhD Students

This paper aims to provide useful advice regarding the development of skills for patient and public involvement and engagement (PPIE) in research. The authors of this paper comprise experienced PhD supervisors and trainers, researchers leading PPIE a... Read More about Patient and Public Involvement and Engagement for PhD Students.

The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controversy (2023)
Journal Article
Dua, H. S., Freitas, R., Mohammed, I., Ting, D. S., & Said, D. G. (2023). The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controversy. Progress in Retinal and Eye Research, 97, Article 101161. https://doi.org/10.1016/j.preteyeres.2022.101161

The pre-Descemet's layer/Dua's layer, also termed the Dua-Fine layer and the pre-posterior limiting lamina layer, lies anterior to the Descemet's membrane in the cornea, is 10 μ m (range 6-16) thick, made predominantly of type I and some type VI coll... Read More about The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controversy.

A Preliminary Psychometric Case Study of the Music in Dementia Assessment Scales: European Portuguese Version (Midas-PT) (2023)
Journal Article
Sousa, L., Moura, B., McDermott, O., & Fernandes, L. (2023). A Preliminary Psychometric Case Study of the Music in Dementia Assessment Scales: European Portuguese Version (Midas-PT). Acta Médica Portuguesa, 36(11), 731-739. https://doi.org/10.20344/amp.18763

Introduction: Music in Dementia Assessment Scales (MiDAS) is a standardized outcome measure aiming to capture the effects of music-based interventions in patients with dementia. It is a unique instrument regarding its specificity, with the potential... Read More about A Preliminary Psychometric Case Study of the Music in Dementia Assessment Scales: European Portuguese Version (Midas-PT).

A comparison of temporal pathways to self-harm in young people compared to adults: A pilot test of the Card Sort Task for Self-harm online using Indicator Wave Analysis (2023)
Journal Article
Lockwood, J., Babbage, C., Bird, K., Thynne, I., Barsky, A., Clarke, D. D., & Townsend, E. (2023). A comparison of temporal pathways to self-harm in young people compared to adults: A pilot test of the Card Sort Task for Self-harm online using Indicator Wave Analysis. Frontiers in Psychiatry, 13, Article 938003. https://doi.org/10.3389/fpsyt.2022.938003

Background: Self-harm is complex, multifaceted, and dynamic, typically starts in adolescence, and is prevalent in young people. A novel research tool (the Card Sort Task for Self-harm; CaTS) offers a systematic approach to understanding this complexi... Read More about A comparison of temporal pathways to self-harm in young people compared to adults: A pilot test of the Card Sort Task for Self-harm online using Indicator Wave Analysis.

Young People’s Trust in Cocreated Web-Based Resources to Promote Mental Health Literacy: Focus Group Study (2023)
Journal Article
Ito-Jaeger, S., Perez Vallejos, E., Logathasan, S., Curran, T., & Crawford, P. (2023). Young People’s Trust in Cocreated Web-Based Resources to Promote Mental Health Literacy: Focus Group Study. JMIR Mental Health, 10, Article e38346. https://doi.org/10.2196/38346

Background:
There is a pressing need to create resources to promote mental health literacy among young people. Digital media is one of the methods that can be used to successfully promote mental health literacy. Although digital mental health resour... Read More about Young People’s Trust in Cocreated Web-Based Resources to Promote Mental Health Literacy: Focus Group Study.

Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects (2023)
Journal Article
Diringer, M., Coliat, P., Mathieu, C., Laurent, N., Mura, C., Banerjee, M., …Detappe, A. (2023). Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects. Small, 19(12), Article 2205961. https://doi.org/10.1002/smll.202205961

Improving the tumor reoxygenation to sensitize the tumor to radiation therapy is a cornerstone in radiation oncology. Here, the pre‐clinical development of a clinically transferable liposomal formulation encapsulating trans sodium crocetinate (NP TSC... Read More about Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects.

Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study (2022)
Journal Article
Labree, B., Hoare, D. J., Fackrell, K., Hall, D. A., Gascoyne, L. E., & Sereda, M. (2022). Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study. Trials, 23(1), Article 1039. https://doi.org/10.1186/s13063-022-07020-2

Background: Tinnitus is the awareness of a sound in the ear or head in the absence of an external source. It affects around 10–15% of people and current treatment options are limited. Experimental treatments include various forms of electrical stimul... Read More about Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study.

Mental health in clinically referred children and young people before and during the Covid-19 pandemic (2022)
Journal Article
Sayal, K., Partlett, C., Bhardwaj, A., Dubicka, B., Marshall, T., Gledhill, J., …Montgomery, A. (2023). Mental health in clinically referred children and young people before and during the Covid-19 pandemic. European Child and Adolescent Psychiatry, 32(12), 2657–2666. https://doi.org/10.1007/s00787-022-02115-2

The Covid-19 pandemic and mitigation approaches, including lockdowns and school closures, are thought to have negatively impacted children and young people’s (CYP) mental health. However, the impact for clinically referred CYP is less clear. We inves... Read More about Mental health in clinically referred children and young people before and during the Covid-19 pandemic.