All Outputs (394)

An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs (2023)
Journal Article
Chow, R. T., Whiting, D., Favril, L., Ostinelli, E., Cipriani, A., & Fazel, S. (2023). An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs. Neuroscience and Biobehavioral Reviews, 155, Article 105454. https://doi.org/10.1016/j.neubiorev.2023.105454

Antipsychotic medications are widely prescribed in psychotic illnesses and other mental disorders. Effectiveness is well-established, particularly for reducing symptoms such as delusions and hallucinations, but can be impacted by tolerability. Advers... Read More about An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs.

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data (2023)
Journal Article
Jack, R. H., Joseph, R. M., Hollis, C., Hippisley-Cox, J., Butler, D., Waldram, D., & Coupland, C. (2023). Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data. BMJ Mental Health, 26(1), Article e300855. https://doi.org/10.1136/bmjment-2023-300855

Background There is an increasing demand for mental health services for young people, which may vary across the year.

Objective To determine whether there are seasonal patterns in primary care antidepressant prescribing and mental health issues in... Read More about Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data.

Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study (2023)
Journal Article
Prasad, V., Rezel-Potts, E., White, P., Downs, J., Boddy, N., Sayal, K., & Sonuga-Barke, E. (2024). Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study. Archives of Disease in Childhood, 109, Article 46-51. https://doi.org/10.1136/archdischild-2023-325637

Objective: To compare use of healthcare services and reasons for attendance by children and young people (CYP) with attention-deficit/hyperactivity disorder (ADHD) versus non-ADHD controls. Design: Population-based matched case-control study. Setting... Read More about Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study.

A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis. (2023)
Journal Article
Chen, K., Weng, Y., Hosseini, A. A., Dening, T., Zuo, G., & Zhang, Y. (2024). A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis. Neural Networks, 169, 442-452. https://doi.org/10.1016/j.neunet.2023.10.040

Alzheimer’s Disease (AD) is a neurodegenerative disease that commonly occurs in older people. It is characterized by both cognitive and functional impairment. However, as AD has an unclear pathological cause, it can be hard to diagnose with confidenc... Read More about A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis..

Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis (2023)
Journal Article
Gosling, C. J., & Sayal, K. (2023). Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis. Lancet Psychiatry, 10(12), 922-933. https://doi.org/10.1016/S2215-0366%2823%2900272-9

Background: The youngest children in a school class are more likely than the oldest to be diagnosed with ADHD, but this relative age effect is less frequent in older than in younger school-grade children. However, no study has explored the associatio... Read More about Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis.

Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial (2023)
Journal Article
Thomson, L., Hassard, J., Frost, A., Bartle, C., Yarker, J., Munir, F., …Blake, H. (2023). Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial. JMIR Research Protocols, 12, Article e48758. https://doi.org/10.2196/48758

Background: Mental health problems affect 1 in 6 workers annually and are one of the leading causes of sickness absence, with stress, anxiety, and depression being responsible for half of all working days lost in the United Kingdom. Primary intervent... Read More about Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial.

Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research (2023)
Journal Article
MacDonald, C., Caimino, C., Burns-O’Connell, G., Hartley, D., Lockwood, J., Sereda, M., …J. Hoare, D. (2023). Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research. Brain Sciences, 13(10), Article 1496. https://doi.org/10.3390/brainsci13101496

Tinnitus (the perception of sound in the absence of any corresponding external source) is highly prevalent and can be distressing. There are unanswered questions about how tinnitus, suicidal thoughts, and suicidal behaviours co-occur and interact. To... Read More about Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research.

Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage (2023)
Journal Article
Eilertsen, H., Menon, C. S., Law, Z. K., Chen, C., Bath, P. M., Steiner, T., …Al-Shahi Salman, R. (2023). Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage. Cochrane Database of Systematic Reviews, 2023(10), Article CD005951.pub5. https://doi.org/10.1002/14651858.CD005951.pub5

Background
Outcome after acute spontaneous (non‐traumatic) intracerebral haemorrhage (ICH) is influenced by haematoma volume. ICH expansion occurs in about 20% of people with acute ICH. Early haemostatic therapy might improve outcome by limiting ICH... Read More about Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage.

Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months (2023)
Journal Article
Nixon, N., Guo, B., Kaylor-Hughes, C., Simpson, S., Garland, A., Dalgleish, T., & Morriss, R. (2024). Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months. Journal of Affective Disorders, 345, 70-77. https://doi.org/10.1016/j.jad.2023.10.105

Background: Despite the known health costs of persistent depression, there is no established service framework for the treatment of this disorder and a lack of long-term outcome data to inform commissioning. To address this gap, we report the long-te... Read More about Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task (2023)
Journal Article
Alfandari, D., Richter, M., Wendt, D., Fiedler, L., & Naylor, G. (2023). Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task. Trends in Hearing, Article 27. https://doi.org/10.1177/23312165231196520

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task (2023)
Journal Article
Alfandari, D., Richter, M., Wendt, D., Fiedler, L., & Naylor, G. (2023). Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task. Trends in Hearing, 27, Article 23312165231196520. https://doi.org/10.1177/23312165231196520

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task.

Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist (2023)
Presentation / Conference Contribution
Christie, H. L., Atefi, G. L., Craven, M. P., Orrell, M., & de Vugt, M. E. (2023, October). Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist. Poster presented at 33rd Alzheimer Europe Conference, Helsinki, Finland

Situation: eHealth interventions are a possible solution for rising dementia care costs and potential negative effects on carers

Problem: Few evidence-based eHealth interventions are implemented in practice

Solution :
Adapt existing implementa... Read More about Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist.

Social anxiety is more likely to influence reputation management decisions than autistic traits (2023)
Journal Article
Dubey, I., Groom, M., Tahir, A., & Hamilton, A. (2024). Social anxiety is more likely to influence reputation management decisions than autistic traits. Autism Research, 17(1), 78-88. https://doi.org/10.1002/aur.3040

People manage their social reputation by selectively sharing achievements, thereby shaping the way others think about them. Autistic traits and social anxiety may have opposing impacts on reputation management. This study aimed to identify the influe... Read More about Social anxiety is more likely to influence reputation management decisions than autistic traits.

Understanding and exploring the cost of poor mental health at work for organisations and society (2023)
Book Chapter
Hassard, J., Thomson, L., & Blake, H. (2024). Understanding and exploring the cost of poor mental health at work for organisations and society. In A. Day, & C. L. Cooper (Eds.), The Routledge Companion to Mental Health at Work. Routledge

This chapter explores the cost of mental health at work from an employer and societal perspective. We aim to present and reflect on the available evidence of the economic burden and human cost posed by poor mental health at work. A fuller understandi... Read More about Understanding and exploring the cost of poor mental health at work for organisations and society.

Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review (2023)
Journal Article
Kalvala, J., Chong, L., Chadborn, N., & Ojha, S. (2023). Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review. BMJ Paediatrics Open, 7(1), Article e002066. https://doi.org/10.1136/bmjpo-2023-002066

Background: Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, br... Read More about Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review.

The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills (2023)
Journal Article
Kubota, M., Hadley, L. V., Schäffner, S., Könend, T., Meaneye, J.-A., Moreyf, C. C., …Chevalier, N. (2023). The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills. Developmental Psychology, 59(11), 2002-2020. https://doi.org/10.1037/dev0001626

The current study investigated the effects of metacognitive and executive function (EF) training on childhood EF (inhibition, working memory [WM], cognitive flexibility, and proactive/reactive control) and academic skills (reading, reasoning, and mat... Read More about The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills.

CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism (2023)
Journal Article
Puzniak, R. J., Prabhakaran, G. T., McLean, R. J., Stober, S., Ather, S., Proudlock, F. A., …Hoffmann, M. B. (2023). CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism. Investigative Ophthalmology & Visual Science, 64(13), Article 14. https://doi.org/10.1167/iovs.64.13.14

Purpose: Albinism is a congenital disorder affecting pigmentation levels, structure, and function of the visual system. The identification of anatomical changes typical for people with albinism (PWA), such as optic chiasm malformations, could become... Read More about CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism.

Management standards and burnout among surgeons in the United Kingdom (2023)
Journal Article
Houdmont, J., Hassard, J., Daliya, P., Adiamah, A., Theophilidou, E., Lobo, D., & East Midlands Surgical Academic Network (EMSAN) Burnout Study Group, E. M. S. A. N. (. B. S. G. (2023). Management standards and burnout among surgeons in the United Kingdom. Occupational Medicine, 73(8), 484-491. https://doi.org/10.1093/occmed/kqad102

Background
Burnout arising from chronic work-related stress is endemic among surgeons in the UK. Identification of contributory and modifiable psychosocial work characteristics could inform risk reduction activities.

Aims
We aimed to assess th... Read More about Management standards and burnout among surgeons in the United Kingdom.

Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis (2023)
Journal Article
Bellato, A., Hall, C. L., Groom, M. J., Simonoff, E., Thapar, A., Hollis, C., & Cortese, S. (2024). Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry, 65(6), 845-861. https://doi.org/10.1111/jcpp.13901

Background
Several computerised cognitive tests (e.g. continuous performance test) have been developed to support the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). Here, we appraised the evidence-base underpinning the use o... Read More about Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis.

Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial (2023)
Preprint / Working Paper
Khan, K., Hall, C. L., Babbage, C., Dodzo, S., Greenhalgh, C., Lucassen, M., Merry, S., Sayal, K., Sprange, K., Stasiak, K., Tench, C. R., Townsend, E., Stallard, P., & Hollis, C. Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial

Background:

A serious game (SPARX), developed in New Zealand and incorporating cognitive behavioural therapy (CBT) principles, has been shown to help reduce symptoms of depression and anxiety in adolescents with mild to moderate depression. Howev... Read More about Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial.